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F. Markland · SciRah

Researcher profile · Semantic Scholar

F. Markland

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F. Markland — researcher profile on SciRah

h-index: 37
Works: 130
Citations: 4,855

Most-cited papers

Snake venoms and the hemostatic system.
F. Markland
1998Toxicon647 citations
Semantic Scholar
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia.
Agustin Garcia, H. Hirte, G. Fleming, Dong-Yun Yang +11 more
2008Journal of Clinical Oncology576 citations
Semantic Scholar
Snake venom metalloproteinases.
F. Markland, S. Swenson
2013Toxicon353 citations
Semantic Scholar
Snake venom fibrin(ogen)olytic enzymes.
S. Swenson, F. Markland
2005Toxicon262 citations
Semantic Scholar
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment.
Dezheng Dong, Bryce Ko, P. Baumeister, S. Swenson +6 more
2005Cancer Research151 citations Open access
Semantic Scholar
Contortrostatin, a snake venom disintegrin, inhibits beta 1 integrin-mediated human metastatic melanoma cell adhesion and blocks experimental metastasis.
M. Trikha, Y. D. de Clerck, F. Markland
1994Cancer Research140 citations
Semantic Scholar
Snake Venom Fibrinogenolytic and Fibrinolytic Enzymes: An Updated Inventory
F. Markland
1998Thrombosis and Haemostasis113 citations
Semantic Scholar
Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression.
S. Swenson, Fritz K. Costa, R. Minea, R. Sherwin +4 more
2004Molecular Cancer Therapeutics104 citations Open access
Semantic Scholar
Hemostasis and animal venoms
H. Pirkle, F. Markland
198886 citations
Semantic Scholar
Inventory of α- and β-Fibrinogenases from Snake Venoms
F. Markland
1991Thrombosis and Haemostasis85 citations
Semantic Scholar
A Novel Snake Venom Disintegrin That Inhibits Human Ovarian Cancer Dissemination and Angiogenesis in an Orthotopic Nude Mouse Model
F. Markland, Kate Shieh, Qing Zhou, V. Golubkov +3 more
2001Pathophysiology of Haemostasis and Thrombosis80 citations Open access
Semantic Scholar
Anti-angiogenesis and RGD-containing snake venom disintegrins.
S. Swenson, Swapnika Ramu, F. Markland
2007Current pharmaceutical design79 citations
Semantic Scholar
Structure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 Å resolution
N. Moiseeva, R. Bau, S. Swenson, F. Markland +3 more
2008Acta Crystallographica Section D: Biological Crystallography70 citations Open access
Semantic Scholar
Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake (Agkistrodon contortrix contortrix).
Alex L. Guan, A. Retzios, G. Henderson, F. Markland
1991Archives of Biochemistry and Biophysics69 citations
Semantic Scholar
Purification and characterization of platelet aggregation inhibitors from snake venoms.
M. Trikha, W. Rote, P. J. Manley, B. Lucchesi +1 more
1994Thrombosis Research66 citations Open access
Semantic Scholar
Contortrostatin, a dimeric disintegrin from Agkistrodon contortrix contortrix, inhibits angiogenesis
Qing Zhou, M. Nakada, C. Arnold, Kate Shieh +1 more
2004Angiogenesis61 citations
Semantic Scholar
Contortrostatin, a dimeric disintegrin from Agkistrodon contortrix contortrix, inhibits breast cancer progression.
Q. Zhou, R. Sherwin, C. Parrish, V. Richters +3 more
2000Breast Cancer Research and Treatment55 citations
Semantic Scholar
Contortrostatin, a Snake Venom Disintegrin with Anti-Angiogenic and Anti-Tumor Activity
S. Swenson, Fritz K. Costa, W. Ernst, G. Fujii +1 more
2006Pathophysiology of Haemostasis and Thrombosis54 citations
Semantic Scholar
Anti-Angiogenic Activity of Contortrostatin, a Disintegrin from Agkistrodon Contortrix Contortrix Snake Venom
V. Golubkov, D. Hawes, F. Markland
2004Angiogenesis53 citations
Semantic Scholar
Contortrostatin, a dimeric disintegrin from contortrix contortrix, inhibits breast cancer progression
Qing Zhou, R. Sherwin, C. Parrish, V. Richters +3 more
2000Breast Cancer Research and Treatment52 citations
Semantic Scholar
Thrombolytic effects of recombinant fibrolase or APSAC in a canine model of carotid artery thrombosis.
F. Markland, G. Friedrichs, Shawn R. Pewitt, B. Lucchesi
1994Circulation52 citations Open access
Semantic Scholar
Defibrinogenating enzymes. Discussion
W. Bell, F. Markland
199746 citations
Semantic Scholar
Development of a chimeric recombinant disintegrin as a cost-effective anticancer agent with promising translational potential
R. Minea, Corey M. Helchowski, B. Rubino, Kyle Brodmann +2 more
2011Toxicon44 citations Open access
Semantic Scholar
Vicrostatin – An Anti-Invasive Multi-Integrin Targeting Chimeric Disintegrin with Tumor Anti-Angiogenic and Pro-Apoptotic Activities
R. Minea, Corey M. Helchowski, Samuel J. Zidovetzki, Fritz K. Costa +2 more
2010PLoS ONE41 citations Open access
Semantic Scholar
Development of a Novel Recombinant Disintegrin, Contortrostatin, as an Effective Anti-Tumor and Anti-Angiogenic Agent
R. Minea, S. Swenson, Fritz K. Costa, Thomas C. Chen +1 more
2006Pathophysiology of Haemostasis and Thrombosis41 citations
Semantic Scholar
Contortrostatin, a Homodimeric Disintegrin, Binds to Integrin αvβ5
Qing Zhou, M. Nakada, P. Brooks, S. Swenson +4 more
200041 citations
Semantic Scholar
Thrombin-like snake venom serine proteinases.
D. J. Phillips, S. Swenson, F. Markland, S. Mackessy
200939 citations
Semantic Scholar
Contortrostatin, a snake venom disintegrin, induces αvβ3‐mediated tyrosine phosphorylation of CAS and FAK in tumor cells
M. Ritter, Qing Zhou, F. Markland
200039 citations
Semantic Scholar
Snake venoms. Discussion
F. Markland, W. Bell
199735 citations
Semantic Scholar
Fibrolase: Trials and Tribulations
F. Markland, S. Swenson
2010Toxins31 citations Open access
Semantic Scholar
Functional Effect of Contortrostatin, a Snake Venom Disintegrin, on Human Glioma Cell Invasion In Vitro
S. Schmitmeier, F. Markland, M. Ritter, D. Sawcer +1 more
2003Cell Communication & Adhesion31 citations Open access
Semantic Scholar
Chemical surface modification of parylene C for enhanced protein immobilization and cell proliferation.
Changhong Zhang, M. Thompson, F. Markland, S. Swenson
2011Acta Biomaterialia30 citations
Semantic Scholar
Anti-invasive effect of contortrostatin, a snake venom disintegrin, and TNF-alpha on malignant glioma cells.
S. Schmitmeier, F. Markland, Thomas C. Chen
2000Anticancer Research27 citations
Semantic Scholar
Integrin Agonists as Adjuvants in Chemotherapy for Melanoma
M. Schwartz, K. McRoberts, Matthew Coyner, K. Andarawewa +6 more
2008Clinical Cancer Research25 citations Open access
Semantic Scholar
Preclinical studies of a novel snake venom-derived recombinant disintegrin with antitumor activity: A review.
A. Schönthal, S. Swenson, Thomas C. Chen, F. Markland
2020Biochemical Pharmacology24 citations Open access
Semantic Scholar
Toxins and Hemostasis
R. Kini, K. J. Clemetson, F. Markland, M. McLane +1 more
201120 citations
Semantic Scholar
Contortrostatin, a homodimeric disintegrin, binds to integrin alphavbeta5.
Q. Zhou, M. Nakada, P. Brooks, S. Swenson +4 more
2000Biochemical and Biophysical Research Communications - BBRC20 citations
Semantic Scholar
Proteolytic cleavage of the beta1 subunit of platelet alpha2beta1 integrin by the metalloproteinase jararhagin compromises collagen-stimulated phosphorylation of pp72.
A. Kamiguti, F. Markland, Q. Zhou, G. Laing +2 more
1997Journal of Biological Chemistry20 citations
Semantic Scholar
Contortrostatin, a Homodimeric Disintegrin, Actively Disrupts Focal Adhesion and Cytoskeletal Structure and Inhibits Cell Motility Through a Novel Mechanism
M. Ritter, Qing Zhou, F. Markland
2001Cell Communication & Adhesion19 citations Open access
Semantic Scholar
Multimeric Disintegrin Protein Polymer Fusions That Target Tumor Vasculature
S. M. Janib, Joshua A Gustafson, R. Minea, S. Swenson +8 more
2014Biomacromolecules17 citations Open access
Semantic Scholar
The role of contortrostatin, a snake venom disintegrin, in the inhibition of tumor progression and prolongation of survival in a rodent glioma model.
P. Pyrko, Wei-Jun Wang, F. Markland, S. Swenson +3 more
2005Journal of Neurosurgery17 citations
Semantic Scholar
Contortrostatin, a snake venom disintegrin, induces alphavbeta3-mediated tyrosine phosphorylation of CAS and FAK in tumor cells.
M. Ritter, Q. Zhou, F. Markland
2000Journal of Cellular Biochemistry16 citations
Semantic Scholar
Contortrostatin, a Homodimeric Disintegrin Isolated from Snake Venom Inhibits Herpes Simplex Virus Entry and Cell Fusion
Stephen Hubbard, Samiksha Choudhary, E. Maus, Deepak Shukla +3 more
2012Antiviral Therapy15 citations
Semantic Scholar
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice
S. Swenson, R. Minea, Cao Duc Tuan, T. Thein +2 more
2018Molecules14 citations Open access
Semantic Scholar
Reversal of Thienopyridine-Induced Platelet Dysfunction Following Desmopressin Administration
Michael Levine, S. Swenson, T. McCormick, S. Henderson +2 more
2012Journal of Medical Toxicology14 citations Open access
Semantic Scholar
Resolution of Isoforms of Natural and Recombinant Fibrinolytic Snake Venom Enzyme Using High Performance Capillary Electrophoresis
F. Markland, S. Morris, J. Deschamps, K. B. Ward
199314 citations
Semantic Scholar
Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells.
V. Golubkov, Agustin Garcia, F. Markland
2005Anticancer Research13 citations
Semantic Scholar
Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the x-ray structure of adamalysin II and atrolysin C
M. Bolger, S. Swenson, F. Markland
2001AAPS PharmSci12 citations Open access
Semantic Scholar
Snake Venom Disintegrin: An Effective Inhibitor of Breast Cancer Growth and Dissemination
F. Markland, Qing Zhou
199911 citations
Semantic Scholar
Nomenclature of Exogenous Hemostatic Factors
D. Aronson, K. Brinkhous, A. Henschen, S. Iwanaga +6 more
1991Thrombosis and Haemostasis11 citations
Semantic Scholar

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