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S. Mackessy · SciRah

Researcher profile · Semantic Scholar

S. Mackessy

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S. Mackessy — researcher profile on SciRah

h-index: 53
Works: 211
Citations: 8,150

Most-cited papers

The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes
D. Schield, D. Card, Nicole R. Hales, B. Perry +12 more
2019Genome Research153 citations Open access
Semantic Scholar
De novo designed proteins neutralize lethal snake venom toxins
Susana Vázquez Torres, M. Bénard-Valle, S. Mackessy, Stefanie K. Menzies +29 more
2025Nature107 citations Open access
Semantic Scholar
Molecular Adaptations for Sensing and Securing Prey and Insight into Amniote Genome Diversity from the Garter Snake Genome
B. Perry, D. Card, J. McGlothlin, Giulia I. M. Pasquesi +28 more
2018Genome Biology and Evolution90 citations Open access
Semantic Scholar
Colubrid Venom Composition: An -Omics Perspective
I. Junqueira-de-Azevedo, P. Campos, A. T. Ching, S. Mackessy
2016Toxins87 citations Open access
Semantic Scholar
Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom
C. Modahl, Mrinalini, Seth Frietze, S. Mackessy
2018Proceedings of the Royal Society of London. Biological Sciences86 citations Open access
Semantic Scholar
De novo designed proteins neutralize lethal snake venom toxins
Susana Vázquez Torres, M. Valle, S. Mackessy, Stefanie K. Menzies +29 more
2024Research Square77 citations Open access
Semantic Scholar
Proteomic analysis reveals geographic variation in venom composition of Russell’s Viper in the Indian subcontinent: implications for clinical manifestations post-envenomation and antivenom treatment
B. Kalita, S. Mackessy, A. Mukherjee
2018Espert Review of Proteomics76 citations
Semantic Scholar
Evidence for divergent patterns of local selection driving venom variation in Mojave Rattlesnakes (Crotalus scutulatus)
Jason L. Strickland, Cara F. Smith, A. Mason, D. Schield +13 more
2018Scientific Reports65 citations Open access
Semantic Scholar
Transcriptomics-guided bottom-up and top-down venomics of neonate and adult specimens of the arboreal rear-fanged Brown Treesnake, Boiga irregularis, from Guam.
D. Pla, D. Petráš, Anthony J. Saviola, C. Modahl +7 more
2018Journal of Proteomics56 citations Open access
Semantic Scholar
Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake
Cara F. Smith, Zachary L. Nikolakis, Kathleen N. Ivey, B. Perry +7 more
2023BMC Biology54 citations Open access
Semantic Scholar
Convergent evolution of toxin resistance in animals
J. van Thiel, M. Khan, R. Wouters, Richard J. Harris +7 more
2022Biological Reviews of The Cambridge Philosophical Society51 citations Open access
Semantic Scholar
Snake recombination landscapes are concentrated in functional regions despite PRDM9.
D. Schield, G. M. Pasquesi, B. Perry, Richard H. Adams +6 more
2020Molecular biology and evolution47 citations
Semantic Scholar
The disintegrin tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells.
Anthony J. Saviola, P. D. Burns, A. Mukherjee, S. Mackessy
2016International Journal of Biological Macromolecules47 citations
Semantic Scholar
Cryptic genetic diversity, population structure, and gene flow in the Mojave rattlesnake (Crotalus scutulatus).
D. Schield, Richard H. Adams, D. Card, Andrew B. Corbin +16 more
2018Molecular Phylogenetics and Evolution46 citations
Semantic Scholar
Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus)
S. Mackessy, Jamie Leroy, E. Mociño-Deloya, K. Setser +2 more
2018Toxins46 citations Open access
Semantic Scholar
Transcriptome-facilitated proteomic characterization of rear-fanged snake venoms reveal abundant metalloproteinases with enhanced activity.
C. Modahl, Seth Frietze, S. Mackessy
2018Journal of Proteomics46 citations
Semantic Scholar
Insight into the roles of selection in speciation from genomic patterns of divergence and introgression in secondary contact in venomous rattlesnakes
D. Schield, Richard H. Adams, D. Card, B. Perry +9 more
2017Ecology and Evolution46 citations Open access
Semantic Scholar
The roles of balancing selection and recombination in the evolution of rattlesnake venom
D. Schield, B. Perry, Richard H. Adams, M. Holding +8 more
2022Nature Ecology & Evolution44 citations Open access
Semantic Scholar
Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities
C. Modahl, S. Mackessy
2019Frontiers in Ecology and Evolution41 citations Open access
Semantic Scholar
Allopatric divergence and secondary contact with gene flow: a recurring theme in rattlesnake speciation
D. Schield, B. Perry, Richard H. Adams, D. Card +8 more
2019Biological Journal of the Linnean Society35 citations Open access
Semantic Scholar
Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution
C. Modahl, S. Mackessy
2016PLoS Neglected Tropical Diseases35 citations Open access
Semantic Scholar
Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites
Shirin Ahmadi, Nick J. Burlet, M. Bénard-Valle, Alid Guadarrama-Martínez +29 more
2025Nature34 citations Open access
Semantic Scholar
Evaluation of cytotoxic activities of snake venoms toward breast (MCF-7) and skin cancer (A-375) cell lines
M. Bradshaw, Anthony J. Saviola, Elizabeth Fesler, S. Mackessy
2016Cytotechnology (Dordrecht)33 citations Open access
Semantic Scholar
Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways
B. Perry, Siddharth S. Gopalan, G. M. Pasquesi, D. Schield +8 more
2022Genome Research32 citations Open access
Semantic Scholar
Venom phenotypes of the Rock Rattlesnake (Crotalus lepidus) and the Ridge‐nosed Rattlesnake (Crotalus willardi) from México and the United States
Anthony J. Saviola, Anthony J Gandara, R. Bryson, S. Mackessy
2017Toxicon30 citations
Semantic Scholar
Venom production and secretion in reptiles.
S. Mackessy
2022Journal of Experimental Biology27 citations Open access
Semantic Scholar
Venom Composition in a Phenotypically Variable Pit Viper ( Trimeresurus insularis) across the Lesser Sunda Archipelago.
B. Jones, Anthony J. Saviola, Sean B. Reilly, Alexander L. Stubbs +5 more
2019Journal of Proteome Research27 citations Open access
Semantic Scholar
Structural and functional characterization of complex formation between two Kunitz-type serine protease inhibitors from Russell's Viper venom.
A. Mukherjee, Sumita Dutta, B. Kalita, D. Jha +2 more
2016Biochimie26 citations
Semantic Scholar
Prevention and improvement of clinical management of snakebite in Southern Asian countries: A proposed road map.
A. Mukherjee, S. Mackessy
2021Toxicon24 citations
Semantic Scholar
Physiological demands and signaling associated with snake venom production and storage illustrated by transcriptional analyses of venom glands
B. Perry, D. Schield, Aundrea K. Westfall, S. Mackessy +1 more
2020Scientific Reports23 citations Open access
Semantic Scholar
Proteomic Deep Mining the Venom of the Red-Headed Krait, Bungarus flaviceps
A. Chapeaurouge, A. Silva, P. Carvalho, Ryan J. R. McCleary +4 more
2018Toxins23 citations Open access
Semantic Scholar
Integration of transcriptomic and proteomic approaches for snake venom profiling
C. Modahl, Anthony J. Saviola, S. Mackessy
2021Espert Review of Proteomics21 citations Open access
Semantic Scholar
Cellular mechanism of resistance of human colorectal adenocarcinoma cells against apoptosis-induction by Russell's Viper venom l-amino acid oxidase (Rusvinoxidase).
A. Mukherjee, Anthony J. Saviola, S. Mackessy
2018Biochimie21 citations
Semantic Scholar
Interspecific and intraspecific venom enzymatic variation among cobras (Naja sp. and Ophiophagus hannah).
C. Modahl, A. Roointan, J. Rogers, Katelyn Currier +1 more
2020Comparative biochemistry and physiology. Toxicology & pharmacology : CBP17 citations
Semantic Scholar
Venom composition of adult Western Diamondback Rattlesnakes (Crotalus atrox) maintained under controlled diet and environmental conditions shows only minor changes.
C. J. Rex, S. Mackessy
2019Toxicon17 citations
Semantic Scholar
Unveiling toxicological aspects of venom from the Aesculapian False Coral Snake Erythrolamprus aesculapii.
M. Sánchez, G. Teibler, J. Sciani, M. G. Casafús +3 more
2019Toxicon16 citations Open access
Semantic Scholar
Multi-species comparisons of snakes identify coordinated signalling networks underlying post-feeding intestinal regeneration
B. Perry, A. Andrew, A. H. Mostafa Kamal, D. Card +7 more
2019Proceedings of the Royal Society B16 citations Open access
Semantic Scholar
Evidence that genomic incompatibilities and other multilocus processes impact hybrid fitness in a rattlesnake hybrid zone
Zachary L. Nikolakis, D. Schield, Aundrea K. Westfall, B. Perry +10 more
2022Evolution; international journal of organic evolution14 citations
Semantic Scholar
Venomics of the central American lyre snake Trimorphodon quadruplex (Colubridae: Smith, 1941) from Costa Rica.
S. Mackessy, W. Bryan, Cara F. Smith, Keira Lopez +5 more
2020Journal of Proteomics13 citations Open access
Semantic Scholar
Assessment of the potential toxicological hazard of the Green Parrot Snake (Leptophis ahaetulla marginatus): Characterization of its venom and venom‐delivery system
M. Sánchez, G. Teibler, C. A. Lopez, S. Mackessy +1 more
2018Toxicon13 citations Open access
Semantic Scholar
Single-Cell Heterogeneity in Snake Venom Expression Is Hardwired by Co-Option of Regulators from Progressively Activated Pathways
Aundrea K. Westfall, Siddharth S. Gopalan, B. Perry, Richard H. Adams +3 more
2023Genome Biology and Evolution12 citations Open access
Semantic Scholar
A plethora of rodents: Rattlesnake predators generate unanticipated patterns of venom resistance in a grassland ecosystem
N. Balchan, Cara F. Smith, S. Mackessy
2023Toxicon: X10 citations Open access
Semantic Scholar
Purification of PaTx-II from the Venom of the Australian King Brown Snake and Characterization of Its Antimicrobial and Wound Healing Activities
R. Samy, S. Mackessy, A. Jeyasankar, Mano Ranjana Ponraj +6 more
2023International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Origins, genomic structure and copy number variation of snake venom myotoxins.
Siddharth S. Gopalan, B. Perry, D. Schield, Cara F. Smith +2 more
2022Toxicon10 citations Open access
Semantic Scholar
Evolution of Resistance to Toxins in Prey
T. McCabe, S. Mackessy
201610 citations
Semantic Scholar
Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling
Cara F. Smith, C. Modahl, David Ceja Galindo, Keira Y Larson +12 more
2023bioRxiv9 citations Open access
Semantic Scholar
Feasibility of detecting snake envenomation biomarkers from dried blood spots
Cara F. Smith, N. Brandehoff, L. Pepin, M. McCabe +5 more
2023Analytical Science Advances9 citations Open access
Semantic Scholar
Venoms of New World Vinesnakes (Oxybelis aeneus and O. fulgidus).
W. Heyborne, S. Mackessy
2020Toxicon9 citations
Semantic Scholar
DNA barcodes from snake venom: a broadly applicable method for extraction of DNA from snake venoms.
Cara F. Smith, Mitchell E. McGlaughlin, S. Mackessy
2018BioTechniques9 citations Open access
Semantic Scholar
Distinct regulatory networks control toxin gene expression in elapid and viperid snakes
C. Modahl, Summer Xia Han, J. van Thiel, Candida Vaz +5 more
2024BMC Genomics8 citations Open access
Semantic Scholar

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