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K. Thijssen · SciRah

Researcher profile · Semantic Scholar

K. Thijssen

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K. Thijssen — researcher profile on SciRah

h-index: 19
Works: 35
Citations: 4,548

Most-cited papers

On the role of RNA amplification in dsRNA-triggered gene silencing.
T. Sijen, J. Fleenor, F. Simmer, K. Thijssen +4 more
2001Cell1,391 citations Open access
Semantic Scholar
Secondary siRNAs Result from Unprimed RNA Synthesis and Form a Distinct Class
T. Sijen, F. Steiner, K. Thijssen, R. Plasterk
2007Science453 citations
Semantic Scholar
C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging
T. V. van Ham, K. Thijssen, R. Breitling, R. Hofstra +2 more
2008PLoS Genetics371 citations Open access
Semantic Scholar
The complete family of genes encoding G proteins of Caenorhabditis elegans
G. Jansen, K. Thijssen, P. Werner, M. van der Horst +2 more
1999Nature Genetics320 citations
Semantic Scholar
Reverse genetics by chemical mutagenesis in Caenorhabditis elegans
G. Jansen, Esther Hazendonk, K. Thijssen, R. Plasterk
1997Nature Genetics286 citations
Semantic Scholar
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi.
J. Pothof, G. van Haaften, K. Thijssen, Ravi S. Kamath +4 more
2003Genes & Development239 citations Open access
Semantic Scholar
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation
A. T. van der Goot, Wentao Zhu, Rafael P. Vázquez-Manrique, Renée I. Seinstra +12 more
2012Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans.
Nadine L. Vastenhouw, Sylvia E. J. Fischer, V. Robert, K. Thijssen +4 more
2003Current Biology200 citations Open access
Semantic Scholar
PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans.
M. Tijsterman, Kristy L. Okihara, K. Thijssen, R. Plasterk
2002Current Biology180 citations Open access
Semantic Scholar
Single nucleotide polymorphisms in wild isolates of Caenorhabditis elegans.
Romke Koch, H. V. Van Luenen, M. van der Horst, K. Thijssen +1 more
2000Genome Research165 citations Open access
Semantic Scholar
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
T. V. van Ham, Mats A. Holmberg, A. T. van der Goot, E. Teuling +12 more
2010Cell147 citations
Semantic Scholar
Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans
F. Steiner, Suzanne W. Hoogstrate, Kristy L. Okihara, K. Thijssen +3 more
2007Nature Structural &Molecular Biology109 citations
Semantic Scholar
SUMOylation promotes protective responses to DNA‐protein crosslinks
Nikoline Borgermann, Leena Ackermann, P. Schwertman, I. Hendriks +5 more
2019EMBO Journal105 citations Open access
Semantic Scholar
C-elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
T. V. van Ham, K. Thijssen, R. Breitling, R. Hofstra +2 more
2017105 citations
Semantic Scholar
Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation
M. van Sluis, Qing Yu, Melanie van der Woude, Camila Gonzalo-Hansen +22 more
2024Nature Cell Biology49 citations Open access
Semantic Scholar
DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals
H. Lans, Jm Lindvall, K. Thijssen, Ae Karambelas +6 more
2013Cell Death and Differentiation43 citations Open access
Semantic Scholar
Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features
M. Sabatella, A. Theil, C. Ribeiro-Silva, J. Slyskova +4 more
2018Nucleic Acids Research35 citations Open access
Semantic Scholar
Tissue-Specific DNA Repair Activity of ERCC-1/XPF-1.
M. Sabatella, K. Thijssen, Carlota Davó-Martínez, W. Vermeulen +1 more
2021Cell Reports33 citations Open access
Semantic Scholar
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
Michele Perni, A. T. van der Goot, Ryan Limbocker, T. V. van Ham +25 more
2021Frontiers in Cell and Developmental Biology24 citations Open access
Semantic Scholar
functional conservation of C. elegans-modifiers of polyglutamine aggregation
E. Teuling, A. Bourgonje, Sven Veenje, K. Thijssen +7 more
201119 citations
Semantic Scholar
Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues
Melanie van der Woude, Carlota Davó-Martínez, K. Thijssen, W. Vermeulen +1 more
2023Nucleic Acids Research12 citations Open access
Semantic Scholar
C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair
K. Thijssen, Melanie van der Woude, Carlota Davó-Martínez, D. Dekkers +4 more
2021Communications Biology12 citations Open access
Semantic Scholar
Modifiers of mutant huntingtin aggregation
E. Teuling, A. Bourgonje, Sven Veenje, K. Thijssen +4 more
2011PLOS Currents12 citations Open access
Semantic Scholar
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure
Alba Muniesa-Vargas, Carlota Davó-Martínez, C. Ribeiro-Silva, Melanie van der Woude +10 more
2024Nature Communications10 citations Open access
Semantic Scholar
A30 Identification of MOAG-4/SERF as a regulator of age related proteotoxicity
R. Burggraaff, T. V. van Ham, Mats A. Holmberg, A. T. van der Goot +12 more
2010Journal of Neurology Neurosurgery & Psychiatry6 citations
Semantic Scholar
RNA polymerase II processing facilitates DNA repair and prevents DNA damage-induced neuronal and developmental failure
Melanie van der Woude, K. Thijssen, M. Sabatella, J. Marteijn +2 more
2025bioRxiv3 citations Open access
Semantic Scholar
Recruitment and release of XPG during NER is controlled by pre- and post-incision factors and EXO1.
Alba Muniesa-Vargas, C. Ribeiro-Silva, Carlota Davó-Martínez, A. Raams +9 more
2026Journal of Cell Biology2 citations
Semantic Scholar
The heterotrimeric G protein genes of Caenorhabditis elegans.
G. Jansen, K. Thijssen, P. Werner, M. van der Horst +2 more
2000Ernst Schering Research Foundation workshop1 citations
Semantic Scholar
Helicase-deficient TFIIH causes severe disease features via persistent DNA excision without damage removal
David Häckes, A. Theil, Geunhee Kim, Youngmin Kim +11 more
2026bioRxiv0 citations Open access
Semantic Scholar
Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1
Alba Muniesa-Vargas, C. Ribeiro-Silva, Bart Geverts, Carlota Davó-Martínez +8 more
2024bioRxiv0 citations Open access
Semantic Scholar
Recovery of protein synthesis to measure transcription-coupled DNA repair in living cells and tissues
Melanie van der Woude, Carlota Davó-Martínez, K. Thijssen, W. Vermeulen +1 more
2023bioRxiv0 citations Open access
Semantic Scholar
Retraction
T. Sijen, F. Steiner, K. Thijssen, R. Plasterk
2020Science0 citations
Semantic Scholar
2.314 Identification of modifiers of alpha-synuclein inclusion in a C. elegans model by genome-wide RNAi
T. V. van Ham, K. Thijssen, R. Breitling, R. Hofstra +2 more
20070 citations
Semantic Scholar
RNA Interference in Caenorhabditis elegans : Mechanism and Application
in-Titia Sijen, Jamie Fleenor, F. Simmer, K. Thijssen +3 more
0 citations
Semantic Scholar

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