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R. Oostendorp · SciRah

Researcher profile · Semantic Scholar

R. Oostendorp

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R. Oostendorp — researcher profile on SciRah

h-index: 11
Works: 20
Citations: 1,312

Most-cited papers

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
L. Niedernhofer, George A. Garinis, A. Raams, A. Lalai +14 more
2006Nature685 citations
Semantic Scholar
The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib
R. Oostendorp, T. Buckle, J. Beijnen, O. van Tellingen +1 more
2009Investigational new drugs158 citations
Semantic Scholar
The biological and clinical role of drug transporters at the intestinal barrier.
R. Oostendorp, J. Beijnen, J. Schellens
2009Cancer Treatment Reviews128 citations
Semantic Scholar
Coadministration of Ritonavir Strongly Enhances the Apparent Oral Bioavailability of Docetaxel in Patients with Solid Tumors
R. Oostendorp, A. Huitema, H. Rosing, R. Jansen +4 more
2009Clinical Cancer Research74 citations Open access
Semantic Scholar
Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.
R. Oostendorp, J. Beijnen, J. Schellens, O. van Tellingen
2007Biomedical chromotography53 citations
Semantic Scholar
Organic Anion-Transporting Polypeptide 1B1 Mediates Transport of Gimatecan and BNP1350 and Can Be Inhibited by Several Classic ATP-Binding Cassette (ABC) B1 and/or ABCG2 Inhibitors
R. Oostendorp, E. van de Steeg, Cornelia M. M. van der Kruijssen, J. Beijnen +3 more
2009Drug Metabolism And Disposition49 citations
Semantic Scholar
In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2
S. Marchetti, R. Oostendorp, D. Pluim, M. V. Van Eijndhoven +6 more
2007Molecular Cancer Therapeutics36 citations
Semantic Scholar
Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.
S. Koolen, R. Oostendorp, J. Beijnen, J. Schellens +1 more
2010British Journal of Clinical Pharmacology31 citations Open access
Semantic Scholar
Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice
R. Oostendorp, T. Buckle, G. Lambert, J. Garrigue +3 more
2010Investigational new drugs27 citations Open access
Semantic Scholar
Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors
R. Oostendorp, P. Witteveen, B. Schwartz, L. Vainchtein +6 more
2010Investigational new drugs25 citations
Semantic Scholar
Targeting cellular adhesion molecules, chemokines and chemokine receptors in rheumatoid arthritis
J. Haringman, R. Oostendorp, P. Tak
2005Expert Opinion on Emerging Drugs23 citations
Semantic Scholar
Is rectal administration an alternative route for imatinib?
N. V. van Erp, R. Oostendorp, H. Guchelaar, J. Schellens +1 more
2007Cancer Chemotherapy and Pharmacology8 citations Open access
Semantic Scholar
The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylate
R. Oostendorp, S. Marchetti, J. Beijnen, R. Mazzanti +1 more
2007Cancer Chemotherapy and Pharmacology7 citations
Semantic Scholar
Bioequivalence study of a new oral topotecan formulation, relative to the current topotecan formulation, in patients with advanced solid tumors.
R. Oostendorp, J. Loftiss, S. Goel, D. Smith +11 more
2009International journal of clinical pharmacology and therapeutics5 citations
Semantic Scholar
Phase I and pharmacological study of orally administered indibulin in advanced solid tumors
R. Oostendorp, P. Witteveen, Brian Schwartz, J. Beijnen +2 more
20072 citations
Semantic Scholar
OATP1B1 mediates transport of gimatecan and BNP1350 and can be inhibited by several classical ABCB1 and/or ABCG2 inhibitors
R. Oostendorp, E. van de Steeg, Cornelia M. M. van der Kruijssen, J. Beijnen +3 more
20081 citations
Semantic Scholar
Preclinical and clinical pharmacology of oral anticancer drugs
R. Oostendorp
20090 citations
Semantic Scholar
The Role of ABC Transporters at the Intestinal Barrier
R. Oostendorp, J. Beijnen, J. Schellens
20090 citations
Semantic Scholar
Determination of the bioequivalence of a new oral topotecan formulation relative to the current formulation in patients with advanced solid tumors
R. Oostendorp, J. Loftiss, S. Goel, Deborah A. Smith +11 more
20080 citations
Semantic Scholar
ABC- transporter studies of Gimatecan (7-t-butoxyiminomethylcamptothecin) in comparison to topotecan
S. Marchetti, R. Oostendorp, D. Pluim, O. van Tellingen +5 more
20060 citations
Semantic Scholar

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J. Beijnen×16
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J. Beijnen — researcher profile on SciRah
J. Schellens×15
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O. van Tellingen×5
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H. Rosing×4
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P. Witteveen×4

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S. Marchetti×3

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T. Buckle — researcher profile on SciRah

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A. Huitema — researcher profile on SciRah

E. van de Steeg×2

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E. van de Steeg — researcher profile on SciRah