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R. Schierwagen · SciRah

Researcher profile · Semantic Scholar

R. Schierwagen

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R. Schierwagen — researcher profile on SciRah

h-index: 38
Works: 219
Citations: 5,106

Most-cited papers

Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
K. Schneider, A. Mohs, Wenfang Gui, Eric J. C. Gálvez +18 more
2022Nature Communications206 citations Open access
Semantic Scholar
Extracellular Matrix Remodeling in Chronic Liver Disease
Cristina Ortiz, R. Schierwagen, L. Schaefer, S. Klein +2 more
2021Current Tissue Microenvironment Reports122 citations Open access
Semantic Scholar
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations
Suguru Nishijima, E. Stankevič, O. Aasmets, T. Schmidt +30 more
2024bioRxiv117 citations Open access
Semantic Scholar
A Consensus Statement on establishing causality, therapeutic applications and the use of preclinical models in microbiome research
A. Metwaly, Aïcha Kriaa, Zahra Hassani, Federica Carraturo +50 more
2025Nature reviews: Gastroenterology & hepatology104 citations Open access
Semantic Scholar
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
Sofia Monteiro, J. Grandt, F. Uschner, N. Kimer +17 more
2020Gut85 citations Open access
Semantic Scholar
State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus.
Julie Rodriguez, Zahra Hassani, Carolina Alves Costa Silva, Fay Betsou +12 more
2024The Lancet Microbe56 citations Open access
Semantic Scholar
Dynamic human liver proteome atlas reveals functional insights into disease pathways
Matthias Mann, L. Niu, P. Geyer, Rajat Gupta +9 more
2022bioRxiv52 citations Open access
Semantic Scholar
Colon Cancer Microbiome Landscaping: Differences in Right- and Left-Sided Colon Cancer and a Tumor Microbiome-Ileal Microbiome Association
B. Kneis, S. Wirtz, K. Weber, Axel Denz +12 more
2023International Journal of Molecular Sciences42 citations Open access
Semantic Scholar
Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial
T. Kronborg, R. Schierwagen, Kajetan Trošt, Qian Gao +10 more
2023Hepatology Communications35 citations Open access
Semantic Scholar
Soluble TIM3 and Its Ligands Galectin-9 and CEACAM1 Are in Disequilibrium During Alcohol-Related Liver Disease and Promote Impairment of Anti-bacterial Immunity
A. Riva, E. Palma, Dhruti Devshi, D. Corrigall +22 more
2021Frontiers in Physiology28 citations Open access
Semantic Scholar
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure
Delia Blaya, Elisa Pose, M. Coll, J. Lozano +12 more
2021JHEP Reports27 citations Open access
Semantic Scholar
Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure
Tao Lin, Shan-Shan Wang, S. Munker, Kyounghwa Jung +29 more
2021Hepatology26 citations Open access
Semantic Scholar
Microbiome testing in Europe: navigating analytical, ethical and regulatory challenges
Julie Rodriguez, Magali Cordaillat-Simmons, N. Badalato, Bernard Berger +58 more
2024Microbiome25 citations Open access
Semantic Scholar
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis
Sandra Torres, M. Brol, F. Magdaleno, R. Schierwagen +15 more
2021Frontiers in Molecular Biosciences24 citations Open access
Semantic Scholar
Myostatin is associated with the presence and development of acute-on-chronic liver failure
A. Ruiz-Margáin, A. Pohlmann, Silke Lanzerath, M. Langheinrich +11 more
2023JHEP Reports21 citations Open access
Semantic Scholar
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
S. Torres, Cristina Ortiz, Nadine Bachtler, W. Gu +18 more
2022Hepatology21 citations Open access
Semantic Scholar
Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1
Cristina Ortiz, S. Klein, W. Reul, F. Magdaleno +21 more
2021Cell Reports19 citations Open access
Semantic Scholar
Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure.
R. Schierwagen, W. Gu, A. Brieger, B. Brüne +29 more
2023American Journal of Physiology - Cell Physiology18 citations Open access
Semantic Scholar
Beta-blockers in patients with liver cirrhosis: Pragmatism or perfection?
T. Sauerbruch, M. Hennenberg, J. Trebicka, R. Schierwagen
2023Frontiers in Medicine16 citations Open access
Semantic Scholar
Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis
Núria Pell, E. García-Pras, Javier Gallego, Salvador Naranjo-Suárez +16 more
2021Molecular Metabolism15 citations Open access
Semantic Scholar
Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes
M. Keller, S. Nishijima, Daniel Podlesny, Chan Yeong Kim +31 more
2025bioRxiv14 citations Open access
Semantic Scholar
Gene score to quantify systemic inflammation in patients with acutely decompensated cirrhosis
J. Trebicka, F. Aguilar, Alberto Queiroz Farias, J. Lozano +52 more
2025Gut14 citations Open access
Semantic Scholar
Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
Sandra Torres, Zeinab Abdullah, M. Brol, C. Hellerbrand +13 more
2020International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells
Nadine Bachtler, Sandra Torres, Cristina Ortiz, R. Schierwagen +10 more
2023PLoS ONE13 citations Open access
Semantic Scholar
The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial
J. K. Hansen, M. Israelsen, S. Nishijima, S. Stinson +31 more
2025Nature Communications12 citations Open access
Semantic Scholar
Terlipressin therapy is associated with increased risk of colonisation with multidrug‐resistant bacteria in patients with decompensated cirrhosis
M. Mücke, María Hernández-Tejero, Wenyi Gu, M. Kuhn +28 more
2024Alimentary Pharmacology and Therapeutics11 citations Open access
Semantic Scholar
Fecal Cytolysin does not predict disease severity in acutely decompensated cirrhosis and acute-on-chronic liver failure
P. Hartmann, S. Lang, R. Schierwagen, S. Klein +3 more
2023Hepatobiliary & Pancreatic Diseases International11 citations Open access
Semantic Scholar
Hepatocellular Cancer Surveillance in Patients with Advanced Chronic Liver Disease.
Wenyi Gu, V. de Lédinghen, C. Aubé, A. Krag +42 more
2024NEJM Evidence10 citations Open access
Semantic Scholar
Soluble urokinase plasminogen activator receptor levels predict survival in patients with portal hypertension undergoing TIPS
S. Loosen, Fabian Benz, R. Mohr, P. Reuken +20 more
2024JHEP Reports7 citations Open access
Semantic Scholar
Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
Carla Cremonese, R. Schierwagen, F. Uschner, Sandra Torres +11 more
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Regulation of uridine diphosphate-glucuronosyltransferase 1A expression by miRNA-214-5p and miRNA-486-3p.
Stefan Paulusch, S. Kalthoff, Steffen Landerer, C. Jansen +4 more
2021Epigenomics6 citations
Semantic Scholar
Lactococcus A phages predict ACLF while Enterococcus B phages predict bacterial infection in decompensated cirrhosis
Lore Van Espen, M. Brol, Lila Close, R. Schierwagen +14 more
2025JHEP Reports5 citations Open access
Semantic Scholar
Stage of fibrosis is not a predictive determinant of weight loss in patients undergoing bariatric surgery.
M. Brol, Uta Drebber, Xiao-Jie Yu, R. Schierwagen +8 more
2024Surgery for Obesity and Related Diseases4 citations Open access
Semantic Scholar
Role of circulating angiogenin levels in portal hypertension and TIPS
Alexander Queck, F. Uschner, P. Ferstl, M. Schulz +9 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Metabolic Signatures of Acinetobacter baumannii and Klebsiella pneumoniae Infections in Acute-on-chronic Liver Failure
Camilla Cadoli, Sania Arif, W. Ballhorn, A. Brieger +16 more
2025Cellular and Molecular Gastroenterology and Hepatology3 citations Open access
Semantic Scholar
Higher prevalence of cytomegalovirus and Epstein–Barr virus in acute-on-chronic liver failure
K. Thiyagarajah, Jannik Sonnenberg, Esra Görgülü, Pia Lembeck +26 more
2025JHEP Reports3 citations Open access
Semantic Scholar
Multidisciplinary Delphi consensus statement on minimal standards for clinical metadata and end points in microbiome studies.
R. Schierwagen, Federica Carraturo, Anandhi Iyappan, M. Brol +16 more
2026Nature reviews: Gastroenterology & hepatology2 citations Open access
Semantic Scholar
Posttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation
Eulàlia Belloc, V. Calderone, Salvador Naranjo-Suárez, Lidia Mateo +15 more
2026Science Advances2 citations Open access
Semantic Scholar
Comparative analysis of SEC61A1 mutant R236C in two patient-derived cellular platforms
Matthias Weiand, V. Sandfort, O. Nadzemova, R. Schierwagen +5 more
2024Scientific Reports2 citations Open access
Semantic Scholar
Association between endotoxemia and blood no in the portal circulation of cirrhotic patients: results of a pilot study
S. Bartimoccia, M. Praktiknjo, C. Nocella, R. Schierwagen +12 more
2024Internal and Emergency Medicine2 citations
Semantic Scholar
CRISPR/Cas9-mediated gene correction of Wilson disease H1069Q point mutation in patient-specific induced pluripotent stem cells.
V. Iwan, O. Nadzemova, Matthias Weiand, A. Zibert +5 more
2026Gene Therapy1 citations Open access
Semantic Scholar
Single-cell RNA sequencing of peripheral blood mononuclear cells in patients with acutely decompensated cirrhosis reveals a specific monocyte subset associated with an increased risk of progression to ACLF
Theresa H. Wirtz, S. Palomino-Echeverria, Maike R. Pollmanns, E. Huergo +30 more
2025medRxiv1 citations Open access
Semantic Scholar
WED-548 Rifaximin-alpha acts through increased abundance of Lactobacillus spp. in murine models of chronic liver disease
M. Brol, C. Alvarez-Silva, R. Schierwagen, F. Uschner +3 more
2024Journal of Hepatology1 citations
Semantic Scholar
Molecular determinants of SEC61A1 mutant R236C in two patient-derived cellular platforms
Matthias Weiand, V. Sandfort, O. Nadzemova, R. Schierwagen +4 more
2023bioRxiv1 citations Open access
Semantic Scholar
New Rat Model of Advanced Non-Alcoholic-Steatohepatitis-Cirrhosis Developing Acute-on-Chronic-Liver failure
Nico Kraus, M. Moeslein, R. Schierwagen, Cristina Ortiz +12 more
2022Zeitschrift für Gastroenterologie - German Journal of Gastroenterology1 citations
Semantic Scholar
New Rat Model of Cholestatic Liver Cirrhosis Developing Acute-on-Chronic-Liver failure
Nico Kraus, M. Moeslein, R. Schierwagen, Cristina Ortiz +12 more
2022Zeitschrift für Gastroenterologie - German Journal of Gastroenterology1 citations
Semantic Scholar
Cohort study evaluating predictors of therapeutic success after sleeve gastrectomy or Roux-en-Y gastric bypass
J. Grandt, Johannes Chang, A. Türler, C. Jansen +7 more
2021Annals of Laparoscopic and Endoscopic Surgery1 citations Open access
Semantic Scholar
SAT-329-YI ACLF metabolic markers can identity or exclude bacterial infections in acutely decompensated cirrhosis
F. Holz, Sania Arif, W. Gu, M. Praktiknjo +19 more
2026Journal of Hepatology0 citations
Semantic Scholar
Pathologische Komplettremission und Mikrobiom – longitudinale Signaturen beim Rektumkarzinom unter neoadjuvanter Therapie
J. Höhn, J. Jentzsch, S. Wirtz, M. Brunner +10 more
2026Zeitschrift für Gastroenterologie - German Journal of Gastroenterology0 citations
Semantic Scholar
SAT-458-YI Beneficial impact of consequent non-selective beta-blocker intake on patient outcomes in all stages of chronic liver disease
Josune Cabello Calleja, C. Junot, Florence A. Castelli, Céline Chollet +11 more
2026Journal of Hepatology0 citations
Semantic Scholar

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