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L. Schaefer · SciRah

Researcher profile · Semantic Scholar

L. Schaefer

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L. Schaefer — researcher profile on SciRah

h-index: 67
Works: 198
Citations: 22K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
R. Iozzo, L. Schaefer
2015Matrix Biology1,090 citations Open access
Semantic Scholar
Complexity of Danger: The Diverse Nature of Damage-associated Molecular Patterns*
L. Schaefer
2014Journal of Biological Chemistry550 citations Open access
Semantic Scholar
Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis.
H. Anders, L. Schaefer
2014Journal of the American Society of Nephrology313 citations Open access
Semantic Scholar
Targeting renal fibrosis: Mechanisms and drug delivery systems
M. Nastase, Jinyang Zeng-Brouwers, M. Wygrecka, L. Schaefer
2017Advanced Drug Delivery Reviews280 citations
Semantic Scholar
Decorin causes autophagy in endothelial cells via Peg3
S. Buraschi, T. Neill, A. Goyal, Chiara Poluzzi +5 more
2013Proceedings of the National Academy of Sciences of the United States of America195 citations Open access
Semantic Scholar
Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity
C. Frevert, Jessica Felgenhauer, M. Wygrecka, M. Nastase +1 more
2018Journal of Histochemistry and Cytochemistry163 citations Open access
Semantic Scholar
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine
A. Theocharis, S. Skandalis, T. Neill, H. Multhaupt +12 more
2015Biochimica et Biophysica Acta150 citations Open access
Semantic Scholar
Proteoglycan neofunctions: Regulation of inflammation and autophagy in cancer biology
L. Schaefer, Claudia Tredup, Maria A. Gubbiotti, R. Iozzo
2016The FEBS Journal148 citations Open access
Semantic Scholar
Decorin as a multivalent therapeutic agent against cancer
T. Neill, L. Schaefer, R. Iozzo
2015Advanced Drug Delivery Reviews136 citations Open access
Semantic Scholar
EphA2 is a functional receptor for the growth factor progranulin
T. Neill, S. Buraschi, A. Goyal, Catherine Sharpe +4 more
2016Journal of Cell Biology127 citations Open access
Semantic Scholar
Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
K. Moreth, Helena Frey, M. Hubo, Jinyang Zeng-Brouwers +6 more
2014Matrix Biology127 citations Open access
Semantic Scholar
Extracellular Matrix Remodeling in Chronic Liver Disease
Cristina Ortiz, R. Schierwagen, L. Schaefer, S. Klein +2 more
2021Current Tissue Microenvironment Reports122 citations Open access
Semantic Scholar
When Place Matters: Shuttling of Enolase-1 Across Cellular Compartments
M. Didiasova, L. Schaefer, M. Wygrecka
2019Front. Cell Dev. Biol.121 citations Open access
Semantic Scholar
Decoding the matrix: Instructive roles of proteoglycan receptors
T. Neill, L. Schaefer, R. Iozzo
2015Biochemistry120 citations Open access
Semantic Scholar
Endostatin and endorepellin: a common route of action for similar angiostatic cancer avengers
Chiara Poluzzi, R. Iozzo, L. Schaefer
2015Advanced Drug Delivery Reviews119 citations Open access
Semantic Scholar
Instructive roles of extracellular matrix on autophagy.
T. Neill, L. Schaefer, R. Iozzo
2014American Journal of Pathology108 citations Open access
Semantic Scholar
Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
Chiara Poluzzi, M. Nastase, Jinyang Zeng-Brouwers, Heiko Roedig +16 more
2019Kidney International106 citations Open access
Semantic Scholar
Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
A. Goyal, T. Neill, R. Owens, L. Schaefer +1 more
2014Matrix Biology88 citations Open access
Semantic Scholar
Soluble biglycan as a biomarker of inflammatory renal diseases
L. T. Hsieh, M. Nastase, Jinyang Zeng-Brouwers, R. Iozzo +1 more
2014International Journal of Biochemistry and Cell Biology85 citations Open access
Semantic Scholar
Biglycan is a new high-affinity ligand for CD14 in macrophages.
Heiko Roedig, M. Nastase, Helena Frey, K. Moreth +7 more
2019Matrix Biology80 citations
Semantic Scholar
Advances in Toll-like receptor biology: Modes of activation by diverse stimuli
C. Bryant, N. Gay, S. Heymans, S. Sacre +2 more
2015Critical reviews in biochemistry and molecular biology79 citations Open access
Semantic Scholar
Targeting GLI Transcription Factors in Cancer
M. Didiasova, L. Schaefer, M. Wygrecka
2018Molecules75 citations Open access
Semantic Scholar
Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy
Maria A. Gubbiotti, T. Neill, Helena Frey, L. Schaefer +1 more
2015Matrix Biology74 citations Open access
Semantic Scholar
Factor XII in coagulation, inflammation and beyond.
M. Didiasova, L. Wujak, L. Schaefer, M. Wygrecka
2018Cellular Signalling73 citations
Semantic Scholar
Analysis of Cell Type-Specific Effects of MicroRNA-92a Provides Novel Insights Into Target Regulation and Mechanism of Action
Eva-Maria Rogg, W. Abplanalp, Corinne Bischof, D. John +8 more
2018Circulation71 citations
Semantic Scholar
Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis
G. Kwapiszewska, A. Gungl, J. Wilhelm, L. Marsh +15 more
2018European Respiratory Journal67 citations Open access
Semantic Scholar
Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology
M. Nastase, R. Iozzo, L. Schaefer
2014Biochimica et Biophysica Acta67 citations Open access
Semantic Scholar
The Role of Decorin and Biglycan Signaling in Tumorigenesis
Valentina Diehl, L. Huber, J. Trebicka, M. Wygrecka +2 more
2021Frontiers in Oncology64 citations Open access
Semantic Scholar
Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy
Heiko Roedig, M. Nastase, M. Wygrecka, L. Schaefer
2019The FEBS Journal62 citations Open access
Semantic Scholar
Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney.
M. Nastase, Jinyang Zeng-Brouwers, Janet Beckmann, Claudia Tredup +4 more
2017Matrix Biology62 citations
Semantic Scholar
Oncosuppressive functions of decorin
T. Neill, L. Schaefer, R. Iozzo
2015Molecular & Cellular Oncology61 citations Open access
Semantic Scholar
Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis
L. T. Hsieh, Helena Frey, M. Nastase, Claudia Tredup +8 more
2015Matrix Biology55 citations Open access
Semantic Scholar
Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19
M. Wygrecka, A. Birnhuber, B. Seeliger, Laura Michalick +21 more
2021Blood Advances54 citations Open access
Semantic Scholar
Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation
J. Barallobre-Barreiro, S. Gupta, A. Zoccarato, Rika Kitazume-Taneike +22 more
2016Circulation52 citations Open access
Semantic Scholar
Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload.
Nadine Beetz, Carolin Rommel, T. Schnick, E. Neumann +12 more
2016Journal of Molecular and Cellular Cardiology52 citations
Semantic Scholar
Decorin differentially modulates the activity of insulin receptor isoform A ligands
A. Morcavallo, S. Buraschi, Shi‐qiong Xu, A. Belfiore +3 more
2014Matrix Biology52 citations Open access
Semantic Scholar
Unilateral dampening of Bmp activity by nodal generates cardiac left-right asymmetry.
J. Veerkamp, Franziska Rudolph, Z. Cseresnyés, Florian Priller +4 more
2013Developmental Cell52 citations Open access
Semantic Scholar
Danger matrix molecules orchestrate CD14/CD44 signaling in cancer development.
Heiko Roedig, R. Damiescu, Jinyang Zeng-Brouwers, Ivan Kutija +3 more
2020Seminars in Cancer Biology51 citations
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury
M. Wygrecka, D. Kosanovic, L. Wujak, K. Reppe +18 more
2017American Journal of Respiratory and Critical Care Medicine47 citations Open access
Semantic Scholar
Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism
Dominik Stammler, T. Eigenbrod, S. Menz, J. Frick +13 more
2015Journal of Immunology46 citations Open access
Semantic Scholar
Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo
S. Fuchs, L. T. Hsieh, W. Saarberg, C. Erdelmeier +4 more
2015Journal of Cellular and Molecular Medicine46 citations Open access
Semantic Scholar
Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases
Jinyang Zeng-Brouwers, Sony Pandey, J. Trebicka, M. Wygrecka +1 more
2020Journal of Histochemistry and Cytochemistry45 citations Open access
Semantic Scholar
Coagulation factor XII regulates inflammatory responses in human lungs
Rosanna Hess, L. Wujak, C. Hesse, K. Sewald +12 more
2017Thrombosis and Haemostasis45 citations Open access
Semantic Scholar
Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores.
J. Schnieder, Argen Mamazhakypov, A. Birnhuber, J. Wilhelm +8 more
2019Matrix Biology44 citations
Semantic Scholar
WW and C2 domain–containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway
A. Hermann, Dirk Oliver Wennmann, Sascha Gromnitza, Maria Edeling +7 more
2018Hepatology44 citations Open access
Semantic Scholar
LRP1: A chameleon receptor of lung inflammation and repair.
L. Wujak, J. Schnieder, L. Schaefer, M. Wygrecka
2017Matrix Biology44 citations
Semantic Scholar
Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis.
M. Grandoch, Christina Kohlmorgen, A. Melchior-Becker, Kathrin Feldmann +15 more
2016Arteriosclerosis, Thrombosis and Vascular Biology44 citations
Semantic Scholar

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