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T. Ludden · SciRah

Researcher profile · Semantic Scholar

T. Ludden

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T. Ludden — researcher profile on SciRah

h-index: 32
Works: 155
Citations: 4,199

Most-cited papers

Likelihood based approaches to handling data below the quantification limit using NONMEM VI
Jae Eun Ahn, M. Karlsson, A. Dunne, T. Ludden
2008Journal of Pharmacokinetics and Pharmacodynamics353 citations
Semantic Scholar
Population pharmacokinetics/dynamics.
L. Sheiner, T. Ludden
1992Annual Review of Pharmacology and Toxicology325 citations
Semantic Scholar
Comparison of the Akaike Information Criterion, the Schwarz criterion and the F test as guides to model selection
T. Ludden, S. L. Beal, L. Sheiner
1994Journal of pharmacokinetics and biopharmaceutics271 citations
Semantic Scholar
Opportunities for Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
C. Peck, W. H. Barr, L. Benet, J. Collins +16 more
1992Clinical pharmacology and therapy181 citations
Semantic Scholar
Population Pharmacokinetic Analysis of Anidulafungin, an Echinocandin Antifungal
J. Dowell, W. Knebel, T. Ludden, M. Stogniew +2 more
2004Journal of clinical pharmacology165 citations
Semantic Scholar
Pharmacokinetic Model of Ascorbic Acid in Healthy Male Volunteers During Depletion and Repletion
J. Graumlich, T. Ludden, C. Conry-Cantilena, Louis R. Jr Cantilena +2 more
1997Pharmaceutical Research158 citations
Semantic Scholar
Population Pharmacokinetic Modeling: The Importance of Informative Graphics
E. Ette, T. Ludden
1995Pharmaceutical Research155 citations
Semantic Scholar
Pharmacokinetic Interactions of the Macrolide Antibiotics
T. Ludden
1985Clinical Pharmacokinetics139 citations
Semantic Scholar
Population pharmacokinetic meta-analysis with efavirenz.
J. Barrett, A. S. Joshi, M. Chai, T. Ludden +2 more
2002International journal of clinical pharmacology and therapeutics99 citations
Semantic Scholar
Effect of erythromycin on carbamazepine kinetics
Yan-Yang Wong, T. Ludden, Rodney D. Bell
1983Clinical pharmacology and therapy81 citations
Semantic Scholar
Are Bioequivalence Studies of Levothyroxine Sodium Formulations in Euthyroid Volunteers Reliable?
V. Blakesley, W. Awni, C. Locke, T. Ludden +2 more
2004Thyroid79 citations
Semantic Scholar
Population Pharmacokinetic–Pharmacodynamic Modeling of Filgrastim (r-metHuG-CSF) in Healthy Volunteers
Bing Wang, T. Ludden, Ellen N. Cheung, G. Schwab +1 more
2001Journal of Pharmacokinetics and Pharmacodynamics61 citations
Semantic Scholar
Population pharmacokinetics of racemic warfarin in adult patients
D. Mungall, T. Ludden, J. Marshall, D. Hawkins +2 more
1985Journal of pharmacokinetics and biopharmaceutics58 citations
Semantic Scholar
Opportunities for Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
C. Peck, W. H. Barr, L. Benet, J. Collins +16 more
1992Pharmaceutical Research57 citations
Semantic Scholar
Population Pharmacokinetic Modelling of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Patients with Haemophilia B
Lei Diao, Shuang-Lian Li, T. Ludden, J. Gobburu +2 more
2014Clinical Pharmacokinetics50 citations Open access
Semantic Scholar
Balanced Designs in Longitudinal Population Pharmacokinetic Studies
E. Ette, He Sun, T. Ludden
1998Journal of clinical pharmacology47 citations
Semantic Scholar
Ocular penetration and pharmacokinetics of topical fluconazole.
Richard W. Yee, Christine J. C. Cheng, Swaminathan Meenakshi, T. Ludden +2 more
1997Cornea47 citations
Semantic Scholar
Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development.
C. Peck, W. H. Barr, L. Benet, J. Collins +16 more
1992Journal of clinical pharmacology44 citations
Semantic Scholar
Pharmacokinetics of Quinidine in Male Patients
C. Verme, T. Ludden, W. A. Clementi, S. Harris
1992Clinical Pharmacokinetics38 citations
Semantic Scholar
Randomized concentration‐controlled trials: Motivations, use, and limitations
H. Kraiczi, T. Jang, T. Ludden, C. Peck
2003Clinical pharmacology and therapy37 citations
Semantic Scholar
Nitrite/thiosulfate treated acute cyanide poisoning: estimated kinetics after antidote.
A. Hall, W. H. Doutré, T. Ludden, K. Kulig +1 more
1987Journal of Toxicology Clinical Toxicology36 citations
Semantic Scholar
Pharmacokinetic study of fludarabine phosphate (NSC 312887)
M. Hersh, J. Kuhn, J. Phillips, G. Clark +2 more
1986Cancer Chemotherapy and Pharmacology36 citations
Semantic Scholar
Population pharmacokinetics of recombinant factor VIII Fc fusion protein
Ivan Nestorov, S. Neelakantan, T. Ludden, Shuang-Lian Li +2 more
2015Clinical pharmacology in drug development34 citations
Semantic Scholar
The pharmacokinetics of pentane, a by-product of lipid peroxidation.
S. Allerheiligen, T. Ludden, R. F. Burk
1987Drug Metabolism And Disposition34 citations
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of Sotalol in Pediatric Patients with Supraventricular or Ventricular Tachyarrhythmia
Jun Shi, T. Ludden, A. Melikian, M. Gastonguay +1 more
2001Journal of Pharmacokinetics and Pharmacodynamics33 citations
Semantic Scholar
Estimation of Population Pharmacokinetic Parameters in the Presence of Non-compliance
S. Mu, T. Ludden
2003Journal of Pharmacokinetics and Pharmacodynamics32 citations
Semantic Scholar
Comparison of Single and Multiple Dose Pharmacokinetics Using Clinical Bioequivalence Data and Monte Carlo Simulations
A. El-Tahtawy, A. Jackson, T. Ludden
1994Pharmaceutical Research32 citations
Semantic Scholar
Clinical Utility of a Bayesian Dosing Program for Phenytoin
M. Privitera, R. Homan, T. Ludden, C. C. Peck +1 more
1989Therapeutic Drug Monitoring32 citations
Semantic Scholar
Population Pharmacokinetic Modeling of Subcutaneously Administered Etanercept in Patients with Psoriasis
I. Nestorov, R. Zitnik, T. Ludden
2004Journal of Pharmacokinetics and Pharmacodynamics30 citations
Semantic Scholar
Effect of food on blood hydralazine levels and response in hypertension
Alexander M. M. Shepherd, N. A. Irvine, T. Ludden
1984Clinical pharmacology and therapy27 citations
Semantic Scholar
Predicting Phenytoin Dosages Using Bayesian Feedback: A Comparison with Other Methods
G. Yuen, Jerry W. Taylor, T. Ludden, Martin J. Murphy
1983Therapeutic Drug Monitoring27 citations
Semantic Scholar
Population Pharmacokinetics of the Active Metabolite of Leflunomide in Pediatric Subjects with Polyarticular Course Juvenile Rheumatoid Arthritis
Jun Shi, S. J. Kovacs, Yaning Wang, T. Ludden +1 more
2005Journal of Pharmacokinetics and Pharmacodynamics26 citations
Semantic Scholar
Computer‐Assisted Drug Assay Interpretation Based on Bayesian Estimation of Individual Pharmacokinetics: Application to Lidocaine
S. Vožeh, R. Hillman, M. Wandell, T. Ludden +1 more
1985Therapeutic Drug Monitoring26 citations
Semantic Scholar
Bioequivalence: Individual and Population Compartmental Modeling Compared to the Noncompartmental Approach
H. Pentikis, James D. Henderson, Nhan L. Tran, T. Ludden
1996Pharmaceutical Research25 citations
Semantic Scholar
Evaluation of Bioequivalence of Highly Variable Drugs Using Monte Carlo Simulations. I. Estimation of Rate of Absorption for Single and Multiple Dose Trials Using Cmax
A. El-Tahtawy, A. Jackson, T. Ludden
1995Pharmaceutical Research25 citations
Semantic Scholar
Metabolism of ethane and pentane to carbon dioxide by the rat.
M. Daugherty, T. Ludden, R. F. Burk
1988Drug Metabolism And Disposition21 citations
Semantic Scholar
Disposition of phenytoin in critically ill trauma patients.
Bradley A. Boucher, John H. Rodman, T. C. Fabian, G. Cupit +3 more
1987Clinical Pharmacist21 citations
Semantic Scholar
On the recording of sample times and parameter estimation from repeated measures pharmacokinetic data
He Sun, E. Ette, T. Ludden
1996Journal of pharmacokinetics and biopharmaceutics20 citations
Semantic Scholar
Pharmacokinetics of high dose melphalan
M. Hersh, T. Ludden, J. Kuhn, William A. Iii Knight
1983Investigational new drugs19 citations
Semantic Scholar
Evaluation of a Bayesian Regression Program for Predicting Warfarin Response
D. Boyle, T. Ludden, B. Carter, A. J. Becker +1 more
1989Therapeutic Drug Monitoring18 citations
Semantic Scholar
Evaluation of theophylline pharmacokinetics in a pediatric population using mixed effects models
M. Driscoll, T. Ludden, D. Casto, L. C. Littlefield
1989Journal of pharmacokinetics and biopharmaceutics17 citations
Semantic Scholar
Absolute bioavailability and dose proportionality of betaxolol in normal healthy subjects.
T. Ludden, D. Boyle, D. Gieseker, G. Kennedy +3 more
1988Journal of Pharmacy and Science17 citations
Semantic Scholar
Effect of oral dose size on hydralazine kinetics and vasodepressor response
Alexander M. M. Shepherd, N. A. Irvine, T. Ludden, Min-Shung Lin +1 more
1984Clinical pharmacology and therapy17 citations
Semantic Scholar
Determination of hydralazine in human whole blood.
T. Ludden, L. K. Ludden, K. E. Wade, S. Allerheiligen
1983Journal of Pharmacy and Science17 citations
Semantic Scholar
Nonlinear Mixed Effects Modeling of Single Dose and Multiple Dose Data for an Immediate Release (IR) and a Controlled Release (CR) Dosage Form of Alprazolam
M. Hossain, E. Wright, R. Baweja, T. Ludden +1 more
1997Pharmaceutical Research16 citations
Semantic Scholar
Bioavailability of controlled release carbamazepine estimated by mixed effect modelling
R. Miller, T. Ludden
2004European Journal of Clinical Pharmacology15 citations
Semantic Scholar
Sensitivity Analysis of the Effect of Bioavailability or Dosage Form Content on Mean Steady State Phenytoin Concentration
T. Ludden, S. Allerheiligen, T. Browne, J. Koup
1991Therapeutic Drug Monitoring15 citations
Semantic Scholar
Bayesian regression analysis of non-steady-state phenytoin concentrations: evaluation of predictive performance.
T. Killilea, R. Coleman, T. Ludden, C. Peck +1 more
1989Therapeutic Drug Monitoring15 citations
Semantic Scholar
Modeling the Exposure‐Response Relationship of Etanercept in the Treatment of Patients With Chronic Moderate to Severe Plaque Psoriasis
M. Hutmacher, I. Nestorov, T. Ludden, R. Zitnik +1 more
2007Journal of clinical pharmacology14 citations
Semantic Scholar
Ignorability and Parameter Estimation in Longitudinal Pharmacokinetic Studies
E. Ette, He Sun, T. Ludden
1998Journal of clinical pharmacology13 citations
Semantic Scholar

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