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J. Barrett · SciRah

Researcher profile · Semantic Scholar

J. Barrett

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J. Barrett — researcher profile on SciRah

h-index: 38
Works: 185
Citations: 5,093

Most-cited papers

Busulfan in infants to adult hematopoietic cell transplant recipients: A population pharmacokinetic model for initial and Bayesian dose personalization
J. McCune, Meagan J. Bemer, J. Barrett, K. Baker +2 more
2013Clinical Cancer Research139 citations Open access
Semantic Scholar
Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients: a population pharmacokinetic analysis
Xiao-Cong Zuo, C. Ng, J. Barrett, Ai-Jing Luo +15 more
2013Pharmacogenetics & Genomics136 citations
Semantic Scholar
A Report from the Pediatric Formulations Task Force: Perspectives on the State of Child-Friendly Oral Dosage Forms
A. Zajicek, M. Fossler, J. Barrett, Jeffrey H. Worthington +9 more
2013AAPS Journal121 citations Open access
Semantic Scholar
Innovative clinical trial design for pediatric therapeutics
M. Laughon, D. Benjamin, E. Capparelli, G. Kearns +6 more
2011Expert Review of Clinical Pharmacology117 citations Open access
Semantic Scholar
A Workflow Example of PBPK Modeling to Support Pediatric Research and Development: Case Study with Lorazepam
A. Maharaj, J. Barrett, A. Edginton
2013AAPS Journal109 citations Open access
Semantic Scholar
Application of Physiologically Based Pharmacokinetic Modeling to Predict Acetaminophen Metabolism and Pharmacokinetics in Children
Xi-Ling Jiang, P. Zhao, J. Barrett, L. Lesko +1 more
2013CPT: Pharmacometrics & Systems Pharmacology108 citations Open access
Semantic Scholar
Drug Dosing in Obese Children: A Systematic Review of Current Pharmacokinetic Data
Margreet W. Harskamp-van Ginkel, Kevin D. Hill, Kristian C. D. Becker, D. Testoni +7 more
2015JAMA pediatrics101 citations Open access
Semantic Scholar
Fluconazole Loading Dose Pharmacokinetics and Safety in Infants
Lauren E. Piper, P. B. Smith, C. Hornik, I. Cheifetz +6 more
2011The Pediatric Infectious Disease Journal98 citations Open access
Semantic Scholar
Safety, dosing, and pharmaceutical quality for studies that evaluate medicinal products (including biological products) in neonates
R. Ward, Daniel Benjamin, J. Barrett, K. Allegaert +3 more
2017Pediatric Research97 citations Open access
Semantic Scholar
History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications
K. Azer, C. Kaddi, J. Barrett, Jane P. F. Bai +9 more
2021Frontiers in Physiology74 citations Open access
Semantic Scholar
Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia.
Karen A. Urtishak, Alena Y. Z. Edwards, Li-San Wang, Amanda R. Hudome +19 more
2013Blood66 citations Open access
Semantic Scholar
Increased Bioavailability of 11‐Keto‐β‐Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures
C. Skarke, Karina Kuczka, L. Tausch, O. Werz +5 more
2012Journal of clinical pharmacology54 citations
Semantic Scholar
Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents.
A. van Rongen, J. Vaughns, G. Moorthy, J. Barrett +2 more
2015British Journal of Clinical Pharmacology50 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO
K. Watt, M. Cohen-Wolkowiez, J. Barrett, M. Sevestre +3 more
2018CPT: Pharmacometrics & Systems Pharmacology42 citations Open access
Semantic Scholar
Fluconazole Population Pharmacokinetics and Dosing for Prevention and Treatment of Invasive Candidiasis in Children Supported with Extracorporeal Membrane Oxygenation
K. Watt, Daniel Gonzalez, D. Benjamin, K. Brouwer +4 more
2015Antimicrobial Agents and Chemotherapy39 citations Open access
Semantic Scholar
Challenges and Opportunities in the Development of Medical Therapies for Pediatric Populations and the Role of Extrapolation
J. Barrett, R. Bishai, C. Bucci-Rechtweg, A. Cheung +8 more
2018Clinical pharmacology and therapy37 citations
Semantic Scholar
Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology and Pharmacology
C. Kaddi, Bradley Niesner, R. Baek, P. Jasper +12 more
2018CPT: Pharmacometrics & Systems Pharmacology37 citations Open access
Semantic Scholar
Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia
Karen A. Urtishak, Li-San Wang, B. Culjkovic-Kraljacic, J. Davenport +21 more
2018Oncogene37 citations Open access
Semantic Scholar
Evaluating Performance of a Decision Support System to Improve Methotrexate Pharmacotherapy in Children and Young Adults with Cancer
Erin Dombrowsky, B. Jayaraman, M. Narayan, J. Barrett
2011Therapeutic Drug Monitoring37 citations Open access
Semantic Scholar
Reduction of soluble CD163, substance P, programmed death 1 and inflammatory markers: phase 1B trial of aprepitant in HIV-1-infected adults
P. Tebas, S. Spitsin, J. Barrett, F. Tuluc +8 more
2015AIDS (London)35 citations Open access
Semantic Scholar
Use of Modeling and Simulation in the Design and Conduct of Pediatric Clinical Trials and the Optimization of Individualized Dosing Regimens
C. Stockmann, J. Barrett, J. Roberts, Catherine M Sherwin
2015CPT: Pharmacometrics & Systems Pharmacology35 citations Open access
Semantic Scholar
Effect of CYP3A5*3 polymorphism on pharmacokinetic drug interaction between tacrolimus and amlodipine.
Xiao-Cong Zuo, Ya-Nan Zhou, Bi-Kui Zhang, Guo-ping Yang +15 more
2013Drug Metabolism and Pharmacokinetics35 citations
Semantic Scholar
Strategic Biomarkers for Drug Development in Treating Rare Diseases and Diseases in Neonates and Infants
Jane P. F. Bai, J. Barrett, G. Burckart, B. Meibohm +2 more
2013AAPS Journal32 citations Open access
Semantic Scholar
Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults
A. van Rongen, M. J. Brill, J. Vaughns, Pyry A. J. Välitalo +5 more
2017Clinical Pharmacokinetics31 citations Open access
Semantic Scholar
Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach
J. M. Brussee, Hui-Xin Yu, E. Krekels, Semra Palić +5 more
2018Pharmaceutical Research30 citations Open access
Semantic Scholar
Development of Drug Therapies for Newborns and Children
Y. Mulugeta, A. Zajicek, J. Barrett, H. Sachs +3 more
2017The Pediatric clinics of North America30 citations Open access
Semantic Scholar
Identifying Novel Phenotypes of Vulnerability and Resistance to Activity-Based Anorexia in Adolescent Female Rats
Nicole C. Barbarich-Marsteller, M. Underwood, R. Foltin, M. Myers +3 more
2013International Journal of Eating Disorders29 citations Open access
Semantic Scholar
Diagnosing malabsorption with systemic lipid profiling: pharmacokinetics of pentadecanoic acid and triheptadecanoic acid following oral administration in healthy subjects and subjects with cystic fibrosis
V. Stallings, J. Mondick, J. Schall, J. Barrett +2 more
2013International journal of clinical pharmacology and therapeutics28 citations Open access
Semantic Scholar
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat
R. Abrams, C. Kaddi, Mengdi Tao, R. Leiser +12 more
2020CPT: Pharmacometrics & Systems Pharmacology26 citations Open access
Semantic Scholar
Challenges and Opportunities With Oncology Drug Development in China
G. Bajaj, M. Gupta, Hwei-gene Heidi Wang, J. Barrett +4 more
2019Clinical pharmacology and therapy25 citations
Semantic Scholar
A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adults
P. Tebas, F. Tuluc, J. Barrett, Wayne Wagner +5 more
2011PLoS ONE25 citations Open access
Semantic Scholar
Adjuvant therapies for HIV-associated neurocognitive disorders
J. McGuire, J. Barrett, H. Vezina, S. Spitsin +1 more
2014Annals of Clinical and Translational Neurology22 citations Open access
Semantic Scholar
Risk Assessment of Drug Interaction Potential and Concomitant Dosing Pattern on Targeted Toxicities in Pediatric Cancer Patients
J. Barrett, D. Patel, Erin Dombrowsky, G. Bajaj +1 more
2013AAPS Journal22 citations Open access
Semantic Scholar
A Sensitive and Selective Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitative Analysis of Efavirenz in Human Plasma
P. Srivastava, G. Moorthy, R. Gross, J. Barrett
2013PLoS ONE21 citations Open access
Semantic Scholar
Prescribing habits and caregiver satisfaction with resources for dosing children: Rationale for more informative dosing guidance
J. Barrett, M. Narayan, D. Patel, A. Zuppa +1 more
2011BMC Pediatrics19 citations Open access
Semantic Scholar
Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV
J. Barrett, S. Spitsin, G. Moorthy, Kyle Barrett +6 more
2016Journal of Translational Medicine18 citations Open access
Semantic Scholar
ABCB1 polymorphism and gender affect the pharmacokinetics of amlodipine in Chinese patients with essential hypertension: a population analysis.
Xiao-Cong Zuo, Wen-Li Zhang, Hong Yuan, J. Barrett +7 more
2014Drug Metabolism and Pharmacokinetics18 citations
Semantic Scholar
A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics
Jeffrey E. Ming, R. Abrams, D. Bartlett, Mengdi Tao +15 more
2017Gene Regulation and Systems Biology17 citations Open access
Semantic Scholar
A hemodynamic model to guide blood pressure control during deliberate hypotension with sodium nitroprusside in children
J. Barrett, S. Hirankarn, N. Holford, G. Hammer +7 more
2015Frontiers in Pharmacology16 citations Open access
Semantic Scholar
Practical Considerations for Dose Selection in Pediatric Patients to Ensure Target Exposure Requirements
A. Barbour, M. Fossler, J. Barrett
2014AAPS Journal16 citations Open access
Semantic Scholar
Predictors of Arterial Blood Pressure Control During Deliberate Hypotension with Sodium Nitroprusside in Children
D. Spielberg, J. Barrett, G. Hammer, D. Drover +3 more
2014Anesthesia and Analgesia16 citations Open access
Semantic Scholar
Model‐Informed Pediatric Drug Development: Application of Pharmacometrics to Define the Right Dose for Children
A. Vinks, J. Barrett
2021Journal of clinical pharmacology15 citations
Semantic Scholar
Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators
Sean T. McQuade, R. Abrams, J. Barrett, B. Piccoli +1 more
2017Gene Regulation and Systems Biology15 citations Open access
Semantic Scholar
A time to keep and a time to cast away categories of tumor response.
M. Maitland, R. Bies, J. Barrett
2011Journal of Clinical Oncology15 citations
Semantic Scholar
Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults.
S. Spitsin, P. Tebas, J. Barrett, V. Pappa +4 more
2017JCI Insight14 citations Open access
Semantic Scholar
Leveraging Big Data in Pediatric Development Programs: Proceedings From the 2016 American College of Clinical Pharmacology Annual Meeting Symposium
Lily Yeruk Mulugeta, Lynne Yao, D. Mould, Brian R. Jacobs +4 more
2018Clinical pharmacology and therapy13 citations
Semantic Scholar
Quantitative system pharmacology as a legitimate approach to examine extrapolation strategies used to support pediatric drug development
K. Azer, J. Barrett
2022CPT: Pharmacometrics & Systems Pharmacology12 citations Open access
Semantic Scholar
Status Toward the Implementation of Precision Dosing in Children
J. Barrett, Ryan Barrett, A. Vinks
2021Journal of clinical pharmacology12 citations
Semantic Scholar
Evaluation of sodium nitroprusside for controlled hypotension in children during surgery
D. Drover, G. Hammer, J. Barrett, C. Cohane +3 more
2015Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Population Pharmacokinetics of Pentobarbital in Neonates, Infants and Children Following Open Heart Surgery
A. Zuppa, S. Nicolson, J. Barrett, M. Gastonguay
2011Jornal de Pediatria12 citations Open access
Semantic Scholar

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