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A. Sapetschnig · SciRah

Researcher profile · Semantic Scholar

A. Sapetschnig

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A. Sapetschnig — researcher profile on SciRah

h-index: 18
Works: 29
Citations: 2,787

Most-cited papers

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans
A. Ashe, A. Sapetschnig, Eva-Maria Weick, Jacinth Mitchell +11 more
2012Cell748 citations Open access
Semantic Scholar
Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to suppress Tc3 Transposon Mobility in the Caenorhabditis elegans germline
P. Das, Marloes P. Bagijn, Leonard D. Goldstein, J. Woolford +11 more
2008Molecules and Cells423 citations Open access
Semantic Scholar
Function, targets and evolution of Caenorhabditis elegans piRNAs
Marloes P. Bagijn, Leonard D. Goldstein, A. Sapetschnig, Eva-Maria Weick +4 more
2012Science375 citations Open access
Semantic Scholar
Transcription factor Sp3 is silenced through SUMO modification by PIAS1
A. Sapetschnig, Grigore Rischitor, H. Braun, A. Doll +3 more
2002EMBO Journal291 citations Open access
Semantic Scholar
Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen.
Bastian Stielow, A. Sapetschnig, Imme Krüger, Natascha Kunert +3 more
2008Molecules and Cells120 citations Open access
Semantic Scholar
Complexity of Translationally Controlled Transcription Factor Sp3 Isoform Expression*
A. Sapetschnig, F. Koch, Grigore Rischitor, Trientje Mennenga +1 more
2004Journal of Biological Chemistry117 citations Open access
Semantic Scholar
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress
Alicia N McMurchy, Przemysław A. Stempor, Tessa Gaarenstroom, Brian Wysolmerski +8 more
2017bioRxiv115 citations Open access
Semantic Scholar
Tertiary siRNAs Mediate Paramutation in C. elegans
A. Sapetschnig, P. Sarkies, N. Lehrbach, E. Miska
2015PLoS Genetics113 citations Open access
Semantic Scholar
Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of Caenorhabditis elegans
L. Kamminga, J. V. van Wolfswinkel, M. J. Luteijn, Lucas J. T. Kaaij +5 more
2012PLoS Genetics110 citations Open access
Semantic Scholar
SUMO‐modified Sp3 represses transcription by provoking local heterochromatic gene silencing
Bastian Stielow, A. Sapetschnig, Christina Wink, Imme Krüger +1 more
2008EMBO Reports103 citations Open access
Semantic Scholar
E2F and Sp1/Sp3 Synergize but Are Not Sufficient to Activate the MYCN Gene in Neuroblastomas*
Christoph Kramps, V. Strieder, A. Sapetschnig, G. Suske +1 more
2004Journal of Biological Chemistry50 citations Open access
Semantic Scholar
A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly
Eyal Maori, I. C. Navarro, H. Boncristiani, D. Seilly +7 more
2019Molecules and Cells48 citations Open access
Semantic Scholar
STC-15, an oral small molecule inhibitor of the RNA methyltransferase METTL3, inhibits tumour growth through activation of anti-cancer immune responses associated with increased interferon signalling, and synergises with T cell checkpoint blockade
Y. Ofir-Rosenfeld, L. Vasiliauskaitė, C. Saunders, A. Sapetschnig +6 more
2022European Journal of Cancer30 citations Open access
Semantic Scholar
Pharmacological Inhibition of the RNA m6a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia
K. Tzelepis, E. De Braekeleer, E. Yankova, Justyna Rak +13 more
2019Blood25 citations Open access
Semantic Scholar
Transcription factor Sp 3 is silenced through SUMO modi ® cation by PIAS 1
A. Sapetschnig, Grigore Rischitor, H. Braun, A. Doll +3 more
24 citations
Semantic Scholar
DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans
Kin M. Suen, F. Braukmann, R. Butler, D. Bensaddek +8 more
2020Nature Communications23 citations Open access
Semantic Scholar
Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNA interference screen
G. Suske, Bastian Stielow, A. Sapetschnig, Imme Krüger +1 more
200820 citations
Semantic Scholar
RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell type
R. Medhi, Jonathan Price, G. Furlan, Beronia Gorges +2 more
2021bioRxiv18 citations Open access
Semantic Scholar
Correction: A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress
Alicia N McMurchy, Przemysław A. Stempor, Tessa Gaarenstroom, Brian Wysolmerski +8 more
2017eLife9 citations Open access
Semantic Scholar
Getting a Grip on piRNA Cluster Transcription
A. Sapetschnig, E. Miska
2014Cell7 citations Open access
Semantic Scholar
High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape
Mohab Helmy, Jin U. Li, Xinyu F. Yan, Rachel K. Meade +29 more
2025Cell Genomics4 citations Open access
Semantic Scholar
1373 STC-15, an oral small molecule inhibitor of the RNA methyltransferase METTL3, inhibits tumour growth through activation of anti-cancer immune responses and synergises with immune checkpoint blockade
Yaara Ofir -Rosenfeld, Oliver Rausch, Jerry McMahon, L. Vasiliauskaitė +7 more
2022Regular and Young Investigator Award Abstracts4 citations Open access
Semantic Scholar
Abstract B126: A small molecule inhibitor of the RNA m6A writer METTL3 inhibits the development of acute myeloid leukemia (AML) in vivo
M. Albertella, W. Blackaby, R. Fosbeary, A. Hendrick +7 more
2019New Molecular Targets3 citations
Semantic Scholar
Direct interaction of PIWI and DEPS-1 is essential for piRNA function and condensate ultrastructure in Caenorhabditis elegans
Kin M. Suen, F. Braukmann, R. Butler, D. Bensaddek +7 more
2019bioRxiv2 citations Open access
Semantic Scholar
The mouse pangenome reveals the structural complexity of the murine protein-coding landscape
Mohab Helmy, Jin U. Li, Xinyu F. Yan, Rachel K. Meade +29 more
2025bioRxiv1 citations Open access
Semantic Scholar
SUMO-modified transcription factors repress transcription by provoking local heterochromatic gene silencing
Bastian Stielow, A. Sapetschnig, Christina Wink, G. Suske
20081 citations
Semantic Scholar
Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer
H. Santos‐Rosa, Jonathan L. Price, Georgia Tsagkogeorga, A. Sapetschnig +8 more
2025bioRxiv0 citations Open access
Semantic Scholar
ThegenerationofpiRNAsfromlongprimarytranscriptsrequiresspecializedfactorsthatdistinguish theseprecursorsfromcanonicalRNApolymeraseIItranscripts.Mohnetal.andZhangetal.provide evidence that in Drosophila melanogaster noncanonical transcription coupled with splicing inhibition differentiates piRNA prec
A. Sapetschnig, E. Miska
20140 citations
Semantic Scholar
perhaps the system could accelerate evolutionary change if it operated at heterozygous loci to silence one allele, thereby allowing phenotypic expression of recessive genes. Future studies are needed to determine whether a similar system exists in other phyla and species.
C. Schubert, E. Youngman, D. Conte, A. Ashe +6 more
20120 citations
Semantic Scholar

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Marloes P. Bagijn×4
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