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E. Youngman · SciRah

Researcher profile · Semantic Scholar

E. Youngman

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E. Youngman — researcher profile on SciRah

h-index: 16
Works: 30
Citations: 7,040

Most-cited papers

Functional profiling of the Saccharomyces cerevisiae genome
G. Giaever, A. Chu, L. Ni, C. Connelly +69 more
2002Nature4,427 citations Open access
Semantic Scholar
Distinct Argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline
Wei-Feng Gu, M. Shirayama, D. Conte, Jessica J. Vasale +15 more
2009Molecules and Cells526 citations Open access
Semantic Scholar
C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts
Heng-Chi Lee, Wei-Feng Gu, M. Shirayama, E. Youngman +2 more
2012Cell365 citations Open access
Semantic Scholar
The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release.
E. Youngman, Julie L. Brunelle, Anna B. Kochaniak, R. Green
2004Cell327 citations Open access
Semantic Scholar
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.
E. Duh, Hoseong S. Yang, I. Suzuma, M. Miyagi +14 more
2002Investigative Ophthalmology and Visual Science322 citations
Semantic Scholar
Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway
Jessica J. Vasale, Wei-Feng Gu, Caroline Thivierge, Pedro J. Batista +5 more
2010Proceedings of the National Academy of Sciences of the United States of America214 citations Open access
Semantic Scholar
CapSeq and CIP-TAP map 5′ ends of Pol II transcripts and reveal capped-small RNAs as C. elegans piRNA precursors
Wei-Feng Gu, Heng-Chi Lee, Daniel A. Chaves, E. Youngman +3 more
2012Cell213 citations Open access
Semantic Scholar
A core nucleosome surface crucial for transcriptional silencing
Jeong-Hyun Park, M. Cosgrove, E. Youngman, C. Wolberger +1 more
2002Nature Genetics144 citations
Semantic Scholar
The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity.
Julie L. Brunelle, E. Youngman, D. Sharma, R. Green
2006RNA: A publication of the RNA Society100 citations Open access
Semantic Scholar
Peptide release on the ribosome: mechanism and implications for translational control.
E. Youngman, M. E. McDonald, R. Green
2008Annual Review of Microbiology96 citations
Semantic Scholar
Affinity purification of in vivo-assembled ribosomes for in vitro biochemical analysis.
E. Youngman, R. Green
2005Methods84 citations
Semantic Scholar
Stop codon recognition by release factors induces structural rearrangement of the ribosomal decoding center that is productive for peptide release.
E. Youngman, Shan L. He, L. J. Nikstad, R. Green
2007Molecules and Cells75 citations Open access
Semantic Scholar
From early lessons to new frontiers: the worm as a treasure trove of small RNA biology
E. Youngman, Julie M. Claycomb
2014Frontiers in Genetics63 citations Open access
Semantic Scholar
Peptide release on the ribosome depends critically on the 2' OH of the peptidyl-tRNA substrate.
Julie L. Brunelle, J. Shaw, E. Youngman, R. Green
2008RNA: A publication of the RNA Society49 citations Open access
Semantic Scholar
Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors.
E. Youngman, Luisa Cochella, Julie L. Brunelle, S. He +1 more
2006Cold Spring Harbor Symposia on Quantitative Biology17 citations Open access
Semantic Scholar
Ribosomal translocation: LepA does it backwards.
E. Youngman, R. Green
2007Current Biology16 citations Open access
Semantic Scholar
Abstract 2460: Development of a highly-sensitive RT-qPCR assay for the detection and quantitation of siRNAs to further understand their role in mRNA quality control in Caenorhabditis elegans
J. Castellani, E. Youngman
2023Journal of Biological Chemistry0 citations Open access
Semantic Scholar
A genetic screen for proteins involved in Non‐Stop mRNA decay in C. elegans
Michelle Diamandi, Catherine M. Brennan, E. Youngman
2022The FASEB Journal0 citations
Semantic Scholar
Genetic dissection of endogenous siRNA involvement in the nonstop decay pathway in C. elegans
Evana Mortezavi, G. L. Wong, E. Youngman
2019The FASEB Journal0 citations
Semantic Scholar
Endogenous siRNAs are required for a learned pathogen avoidance behavior in Caenorhabditis elegans
Yazmine Manzanet, Nicholas A. Salerno, E. Youngman
2019The FASEB Journal0 citations
Semantic Scholar
Quantifying Downstream Regulatory Output as a Way to Understand the Biogenesis Pathways of Endogenous siRNAs in C. elegans
L. Izzo, E. Youngman
2017The FASEB Journal0 citations
Semantic Scholar
Investigating the Heritability of a Learned Pathogen Avoidance Behavior in Caenorhabditis elegans
Laura E. Meissner, Gabriella A. Manilla, Taylor G. Brown, E. Youngman
2017The FASEB Journal0 citations
Semantic Scholar
Nonstop Decay in C. elegans: Examination of a Possible Role for Small Noncoding RNAs
E. Youngman
2017The FASEB Journal0 citations
Semantic Scholar
Regulation of wago‐1: An Examination of the Regulatory Architecture that Governs Argonaute Protein Expression in Caenorhabditis elegans
Erin A. Rosenberg, E. Youngman
2016The FASEB Journal0 citations
Semantic Scholar
Nonstop Decay in C. elegans: Examination of a Possible Role for Endogenous siRNAs
E. Youngman, Wei-Feng Gu, C. Mello
2016The FASEB Journal0 citations
Semantic Scholar
perhaps the system could accelerate evolutionary change if it operated at heterozygous loci to silence one allele, thereby allowing phenotypic expression of recessive genes. Future studies are needed to determine whether a similar system exists in other phyla and species.
C. Schubert, E. Youngman, D. Conte, A. Ashe +6 more
20120 citations
Semantic Scholar
A mechanistic study of peptide bond formation and peptide release on the ribosome
E. Youngman
20070 citations
Semantic Scholar
Whither Arctic Sea Ice? - An Earth Exploration Toolbook chapter on the climate's canary in a coal mine
W. Meier, E. Youngman, L. Dahlman
20070 citations
Semantic Scholar
Corrigendum to “Affinity purification of in vivo-assembled ribosomes for in vitro biochemical analysis” [Methods 36 (2005) 305–312]
E. Youngman, R. Green
20060 citations
Semantic Scholar
Molecular dissection of ribosome function in two active sites
R. Green, Julie L. Brunelle, Luisa Cochella, Silke Dorner +3 more
20060 citations
Semantic Scholar

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