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T. Fu · SciRah

Researcher profile · Semantic Scholar

T. Fu

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T. Fu — researcher profile on SciRah

h-index: 24
Works: 81
Citations: 3,493

Most-cited papers

Gasdermin D pore structure reveals preferential release of mature interleukin-1
S. Xia, Zhi-Bin Zhang, V. Magupalli, J. Pablo +9 more
2021Nature568 citations Open access
Semantic Scholar
Global modeling of secondary organic aerosol formation from aromatic hydrocarbons: high- vs. low-yield pathways
D. Henze, J. H. Seinfeld, N. L. Ng, Jesse H. Kroll +3 more
2007404 citations Open access
Semantic Scholar
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
Yu-Ru Lee, Ming Chen, Jonathan D. Lee, Jinfang Zhang +23 more
2019Science309 citations Open access
Semantic Scholar
Phase Separation Drives RNA Virus-Induced Activation of the NLRP6 Inflammasome
Chen Shen, Run-Zhi Li, R. Negro, Jie-Wei Cheng +10 more
2021Cell205 citations Open access
Semantic Scholar
Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death Inducing Signaling Complex
T. Fu, Yang Li, A. Lu, Zongli Li +9 more
2016Molecules and Cells175 citations Open access
Semantic Scholar
Molecular basis of caspase-1 polymerization and its inhibition by a novel capping mechanism
A. Lu, Yang Li, F. Schmidt, Q. Yin +6 more
2016Nature Structural &Molecular Biology171 citations Open access
Semantic Scholar
Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor
Q. Fu, T. Fu, Anthony C. Cruz, Prabuddha Sengupta +5 more
2016Molecules and Cells171 citations Open access
Semantic Scholar
Structures and gating mechanism of human TRPM2
Long-Fei Wang, T. Fu, Yi-Ming Zhou, S. Xia +2 more
2018Science161 citations Open access
Semantic Scholar
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold
P. Fontana, Ying Dong, X. Pi, Alexander B. Tong +5 more
2022Science159 citations Open access
Semantic Scholar
Structures of a complete human V-ATPase reveal mechanisms of its assembly
Long-Fei Wang, Di Wu, C. Robinson, Hao Wu +1 more
2020Molecules and Cells151 citations Open access
Semantic Scholar
INAUGURAL ARTICLE by a Recently Elected Academy Member:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1
Yang Li, T. Fu, A. Lu, K. Witt +3 more
2018140 citations Open access
Semantic Scholar
Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling
L. Pan, T. Fu, Wen-Yi Zhao, Linlin Zhao +9 more
2019Cell134 citations Open access
Semantic Scholar
Structural Biology of Innate Immunity
Q. Yin, T. Fu, Ji-Xi Li, Hao Wu
2015Annual Review of Immunology124 citations Open access
Semantic Scholar
Molecular mechanism for NLRP6 inflammasome assembly and activation
Chen Shen, A. Lu, Wen-Jun Xie, J. Ruan +4 more
2019Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Abstract B122: Molecular mechanism of V(D)J recombination from synaptic RAG1-RAG2 complex structures
H. Ru, M. Chambers, T. Fu, Alexander B. Tong +2 more
2016110 citations
Semantic Scholar
Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion
Setu M. Vora, P. Fontana, T. Mao, V. Léger +8 more
2021bioRxiv101 citations Open access
Semantic Scholar
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair
Pengda Liu, Wenjian Gan, Siyuan Su, Arthur V. Hauenstein +6 more
2018Science Signaling92 citations Open access
Semantic Scholar
Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures
H. Ru, M. Chambers, T. Fu, Alexander B. Tong +2 more
2015Cell88 citations Open access
Semantic Scholar
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes
L. R. Hollingsworth, L. David, Yang Li, A. R. Griswold +7 more
2021Nature Communications69 citations Open access
Semantic Scholar
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism
Ming Shi, Long-Fei Wang, P. Fontana, Setu M. Vora +4 more
2020bioRxiv68 citations Open access
Semantic Scholar
Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of its Self-association to DED/DED Interactions
A. Lu, V. Kabaleeswaran, T. Fu, V. Magupalli +1 more
2014Journal of Molecular Biology58 citations Open access
Semantic Scholar
Targeted delivery of RNAi to cancer cells using RNA-ligand displaying exosome
N. Uddin, Daniel W. Binzel, Dan Shu, T. Fu +1 more
2022Acta Pharmaceutica Sinica B56 citations Open access
Semantic Scholar
Higher-order assemblies in immune signaling: supramolecular complexes and phase separation
S. Xia, Zhen-Hang Chen, Chen Shen, T. Fu
2021Protein & Cell47 citations Open access
Semantic Scholar
Mechanism of ubiquitin transfer promoted by TRAF6
T. Fu, Chen Shen, Qiu-Bai Li, Pengfei Zhang +1 more
2018Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175
Wang Zheng, Chen Shen, Long-Fei Wang, S. Rawson +8 more
2022Science Advances44 citations Open access
Semantic Scholar
Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy
L. Yin, G. Masuyer, Si-Cai Zhang, Jie Zhang +7 more
2020PLoS Biology24 citations Open access
Semantic Scholar
INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling
P. Luong, M. Hedl, Jie Yan, Tao Zuo +8 more
2018eLife21 citations Open access
Semantic Scholar
Crystal structures of cobalamin-independent methionine synthase (MetE) from Streptococcus mutans: a dynamic zinc-inversion model.
T. Fu, J. Almqvist, Yu-He Liang, Lan-Fen Li +2 more
2011Journal of Molecular Biology17 citations
Semantic Scholar
Mechanism of TRPM2 channel gating revealed by cryo-EM
S. Xia, Long-Fei Wang, T. Fu, Hao Wu
2019The FEBS Journal16 citations Open access
Semantic Scholar
Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining
Longfei Wang, Di Wu, C. Robinson, T. Fu
2022Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis
Cheng-Yong Wu, Dong-Mei Tang, Jie Cheng, Daojun Hu +7 more
2021Nucleic Acids Research11 citations Open access
Semantic Scholar
Structural basis for the autoinhibition of the C-terminal kinase domain of human RSK1.
Dan Li, T. Fu, J. Nan, Cong Liu +2 more
2012Acta Crystallographica Section D: Biological Crystallography11 citations
Semantic Scholar
Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer
Anthony D. Rish, Zhang-Fei Shen, Zhen-Hang Chen, Nan Zhang +2 more
2022bioRxiv8 citations Open access
Semantic Scholar
The structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification.
T. Fu, Xiang Liu, Lan-Fen Li, Xiao-Dong Su
2010Acta Crystallographica. Section F : Structural Biology and Crystallization Communications8 citations Open access
Semantic Scholar
Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes
L. R. Hollingsworth, L. David, Yang Li, A. R. Griswold +6 more
2020bioRxiv5 citations Open access
Semantic Scholar
Inflammation NODs to Antagonists of RIP2-XIAP Interaction
S. Xia, T. Fu, Hao Wu
2018Molecules and Cells4 citations Open access
Semantic Scholar
Purification and cryoelectron microscopy structure determination of human V-ATPase
Long-Fei Wang, Zhen-Hang Chen, Hao Wu, T. Fu
2021STAR Protocols2 citations Open access
Semantic Scholar
Insights into gasdermin pore formation from the structure of a pre‐pore
S. Xia, J. Ruan, T. Fu, Hao Wu
2019The FASEB Journal1 citations
Semantic Scholar
Protein preparation, crystallization and preliminary X-ray analysis of the C-terminal domain of human RSK1 serine/threonine protein kinase.
T. Fu, Dan Li, J. Nan, Lan-Fen Li +2 more
2007Acta Crystallographica. Section F : Structural Biology and Crystallization Communications1 citations Open access
Semantic Scholar
Preparation, crystallization and preliminary X-ray analysis of the methionine synthase (MetE) from Streptococcus mutans.
T. Fu, Xiao-Yan Zhang, Lan-Fen Li, Yu-He Liang +1 more
2006Acta Crystallographica. Section F : Structural Biology and Crystallization Communications1 citations Open access
Semantic Scholar
CRISPR-Cas has a new juggling act: interplay between nuclease and protease
Anthony D. Rish, T. Fu
2023Nature Structural & Molecular Biology0 citations Open access
Semantic Scholar
Structure of membrane protein with ions
C. Shen, T. Fu, L.-F. Wang, S. Rawson +1 more
20210 citations
Semantic Scholar
Structure of a trans-membrane protein
C. Shen, T. Fu, L.-F. Wang, S. Rawson +1 more
20210 citations
Semantic Scholar
Plasmodium falciparum vacuolar pyrophosphatase 1 for ring stage development and its transition to trophozoite
Omobukola Solebo, Li-Qin Ling, Jing Zhou, T. Fu +1 more
2021bioRxiv0 citations Open access
Semantic Scholar
Structure of an Apo membrane protein
C. Shen, T. Fu, L.-F. Wang, S. Rawson +1 more
20210 citations
Semantic Scholar
Human V-ATPase in state 3 with SidK and ADP
L. Wang, H. Wu, T. Fu
20200 citations
Semantic Scholar
Cryo-EM structure of the NLRP1-CARD filament
L. R. Hollingsworth, L. David, Y. Li, H. Sharif +3 more
20200 citations
Semantic Scholar
Human V-ATPase in state 1 with SidK and ADP
L. Wang, H. Wu, T. Fu
20200 citations
Semantic Scholar
The Vo region of human V-ATPase in state 1 (focused refinement)
L. Wang, H. Wu, T. Fu
20200 citations
Semantic Scholar
Cryo-EM structure of CARD8-CARD filament
L. R. Hollingsworth, L. David, Y. Li, H. Sharif +3 more
20200 citations
Semantic Scholar

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