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Tyler Izatt · SciRah

Researcher profile · Semantic Scholar

Tyler Izatt

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Tyler Izatt — researcher profile on SciRah

h-index: 15
Works: 43
Citations: 19K

Most-cited papers

A global reference for human genetic variation
Taras K. Oleksyk, Adam Gonçalo R. David M. Richard M. Gonçalo R. David R. Auton Abecasis Altshuler Durbin Abecasis Bentley C, Adam Gonçalo R. Auton Abecasis, Adam Auton +496 more
2015Nature17K citations Open access
Semantic Scholar
Germline Mutations in HOXB13 and Prostate-Cancer Risk
C. Ewing, Anna M. Ray, Ethan M. Lange, K. Zuhlke +21 more
2012New England Journal of Medicine658 citations Open access
Semantic Scholar
Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma
M. Borad, Mia D. Champion, J. Egan, W. Liang +45 more
2014PLoS Genetics336 citations Open access
Semantic Scholar
Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities
David W. Craig, J. O'Shaughnessy, J. Kiefer, Jessica Aldrich +24 more
2012Molecular Cancer Therapeutics217 citations
Semantic Scholar
Personalized treatment of Sézary syndrome by targeting a novel CTLA4:CD28 fusion
A. Sekulic, W. Liang, Waibhav Tembe, Tyler Izatt +12 more
2014Molecular Genetics & Genomic Medicine85 citations Open access
Semantic Scholar
Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing
W. Liang, David W. Craig, J. Carpten, M. Borad +25 more
2012PLoS ONE75 citations Open access
Semantic Scholar
Extramedullary Myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease
J. Egan, K. Kortuem, Ahmet A. Kurdoglu, Tyler Izatt +10 more
2013British Journal of Haematology57 citations Open access
Semantic Scholar
Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis
N. Dizman, Y. Lyou, N. Salgia, P. Bergerot +6 more
2020Journal for ImmunoTherapy of Cancer45 citations Open access
Semantic Scholar
Paired Tumor and Normal Whole Genome Sequencing of Metastatic Olfactory Neuroblastoma
G. Weiss, W. Liang, Tyler Izatt, Shilpi Arora +13 more
2012PLoS ONE39 citations Open access
Semantic Scholar
A Pilot Study Using Next-Generation Sequencing in Advanced Cancers: Feasibility and Challenges
G. Weiss, W. Liang, M. Demeure, J. Kiefer +14 more
2013PLoS ONE38 citations Open access
Semantic Scholar
Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers
M. Borad, J. Egan, Rachel M. Condjella, W. Liang +33 more
2016Scientific Reports30 citations Open access
Semantic Scholar
Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer
Vijayalakshmi Shanmugam, R. Ramanathan, Nicole A. Lavender, Shripad A. Sinari +13 more
2014BMC Medical Genomics21 citations Open access
Semantic Scholar
Simultaneous Characterization of Somatic Events and HPV-18 Integration in a Metastatic Cervical Carcinoma Patient Using DNA and RNA Sequencing
Winnie S. Liang, Jessica Aldrich, S. Nasser, Ahmet A. Kurdoglu +16 more
2014International Journal of Gynecologic Cancer19 citations Open access
Semantic Scholar
Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability
M. Demeure, David W. Craig, Shripad A. Sinari, Tracy M. Moses +14 more
2012Genome Medicine17 citations Open access
Semantic Scholar
Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
Sara A. Byron, W. Hendricks, A. Nagulapally, J. Kraveka +35 more
2021Cancer Research15 citations Open access
Semantic Scholar
An Integrated Framework for Reporting Clinically Relevant Biomarkers from Paired Tumor/Normal Genomic and Transcriptomic Sequencing Data In Support of Clinical Trials in Personalized Medicine
S. Nasser, Ahmet A. Kurdolgu, Tyler Izatt, Jessica Aldrich +13 more
2014Pacific Symposium on Biocomputing15 citations
Semantic Scholar
Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial
G. Sholler, Genevieve Bergendahl, Elizabeth C Lewis, J. Kraveka +27 more
2024Genome Medicine14 citations Open access
Semantic Scholar
Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.
S. Sakthikumar, Manisha Warrier, Derick Whitley, Salvatore J. Facista +28 more
2023Veterinary and Comparative Oncology13 citations Open access
Semantic Scholar
A novel FBXO28 frameshift mutation in a child with developmental delay, dysmorphic features, and intractable epilepsy: A second gene that may contribute to the 1q41‐q42 deletion phenotype
Chris Balak, N. Belnap, K. Ramsey, S. Joss +18 more
2018American Journal of Medical Genetics. Part A12 citations
Semantic Scholar
Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial
P. LoRusso, A. Sekulic, J. Sosman, W. Liang +43 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib
A. Bryce, M. Borad, J. Egan, Rachel M. Condjella +32 more
2016Clinical Genitourinary Cancer3 citations Open access
Semantic Scholar
Abstract 4493: Germline findings in targeted tumor sequencing using matched normal DNA
Subha Krishnan, G. Basu, Laura Gonzalez-Malerva, Thomas E. Royce +16 more
20163 citations
Semantic Scholar
ARID1A alterations in gastrointestinal cancers as therapeutic opportunities.
G. Basu, T. White, J. LoBello, Kevin R Lau +15 more
20162 citations
Semantic Scholar
Alterations in the cell cycle checkpoint pathway in breast cancer.
G. Basu, T. White, J. LoBello, Ahmet A. Kurdoglu +12 more
2015Journal of Clinical Oncology2 citations
Semantic Scholar
Abstract A006: Increased germline mutational burden in individuals of African ancestry: Implications for interpretation of tumor mutation burden
Janith Don, Sara A. Byron, Guang-Fa Zhang, Tyler Izatt +7 more
2023Cancer Epidemiology, Biomarkers & Prevention1 citations
Semantic Scholar
Abstract 3679: Paired tumor and normal whole genome and transcriptome sequencing of transitional cell carcinoma of the upper urinary tract
Irene Cherni, David W. Craig, Lori Phillips, W. Liang +10 more
20121 citations
Semantic Scholar
Abstract 2495: Rapid clinical diagnostic classification and risk stratification in acute myelogenous leukemia (AML) using whole genome sequencing (WGS)
Wayne M. Jepsen, J. Keats, S. Byron, Cherie Wesley +14 more
2026Cancer Research0 citations
Semantic Scholar
PA-240 Impact of Clinical Whole Genome Sequencing in Immunotherapy-Exposed Patients
Jonathan J. Keats, Murali Janakiram, S. Goldsmith, M. Rosenzweig +20 more
2026Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
PA-381 Rapid Clinical Whole-Genome Sequencing Provides Real-Time Risk Stratification and Immunotherapy Selection in Multiple Myeloma
Wayne M. Jepsen, Tracey White, Cherie Wesley, Bryce Turner +18 more
2026Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
ALTseqTM, a rapid (< 48 hours) whole genome sequencing clinical test for Acute Myeloid Leukemia (AML)
Wayne M. Jepsen, J. Keats, Sara Byron, Cherie Wesley +14 more
2025Blood0 citations
Semantic Scholar
Abstract C039: Influence of patient ancestry on homologous recombination repair deficiency in cancer
Sara A. Byron, Guang-Fa Zhang, Kimber Slater, Jiaming Zhang +8 more
2023Cancer Epidemiology, Biomarkers & Prevention0 citations
Semantic Scholar
Abstract CT089: Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial
Giselle L. Saulner Sholler, J. Kraveka, Genevieve Bergendahl, Elizabeth C Lewis +26 more
2023Cancer Research0 citations
Semantic Scholar
Integrated whole-exome and transcriptome analysis of 250 treatment-refractory or relapsed (R/R) childhood solid tumors.
Sara A. Byron, W. Hendricks, A. Nagulapally, K. Dykema +15 more
2021Journal of Clinical Oncology0 citations
Semantic Scholar
Table of Contents, Volume 176A, Number 7, July 2018
AmbroiseWonkam KattaM Girisha, andMaximilianMuenke, Chris Balak, N. Belnap +47 more
2018American Journal of Medical Genetics. Part A0 citations Open access
Semantic Scholar
Abstract PR06: Precision medicine for newly diagnosed and refractory/recurrent pediatric cancer patients: Lessons learned from “N=1” studies
Troy A. McEachron, Keri B. Zabokrtsky, A. Sassoon, S. Nasser +5 more
20160 citations
Semantic Scholar
The value of sequencing germline DNA for accurate determination of somatic mutations in large-panel next-generation-sequencing-based tumor testing.
T. McDaniel, T. White, Ahmet A. Kurdoglu, J. LoBello +7 more
20150 citations
Semantic Scholar
A study of real-time CLIA-enabled whole genome tumor sequencing: Results for testicular cancer and sarcomatoid RCC.
A. Bryce, M. Borad, Rachel M. Condjella, J. Egan +15 more
20140 citations
Semantic Scholar
Abstract 2023: Whole exome and RNA sequencing reveals genetic alterations in DNA damage and homologous recombination pathways in triple negative breast cancer.
Shukmei Wong, J. O'Shaughnessy, P. LoRusso, Jessica Aldrich +16 more
20130 citations
Semantic Scholar
Abstract 5104: Identification of key tumorigenic pathways in pancreatic adenocarcinoma patients using massively parallel DNA and RNA sequencing
W. Liang, David W. Craig, J. Carpten, M. Borad +20 more
20120 citations
Semantic Scholar
Abstract 5072: Genome sequencing of metastatic colorectal carcinomas to identify potential targets for therapy in patients
Viji Shanmugam, R. Ramanathan, Shripad A. Sinari, M. Chadha +11 more
20120 citations
Semantic Scholar
Abstract 5068: Identification of key tumorigenic pathways in never-smoker lung adenocarcinoma using massively parallel DNA and RNA sequencing and methylation profiling
T. Whitsett, Irene Cherni, L. Inge, B. Salhia +20 more
20120 citations
Semantic Scholar
Abstract A43: Identification of key tumorigenic pathways in never-smoker lung adenocarcinoma patients using massively parallel DNA and RNA sequencing
T. Whitsett, Shripad A. Sinari, Kelly W. Sheff, P.-Y. Cheung +21 more
2012Clinical Cancer Research0 citations
Semantic Scholar
Abstract A183: Whole-genome sequencing to find potential targets for therapy in patients with refractory K-ras mutated metastatic colorectal cancer.
R. Ramanathan, Viji Shanmugam, Shripad A. Sinari, M. Chadha +10 more
20110 citations
Semantic Scholar

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David W. Craig — researcher profile on SciRah
J. Carpten×28
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Ahmet A. Kurdoglu×22
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