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Jessica Aldrich · SciRah

Researcher profile · Semantic Scholar

Jessica Aldrich

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Jessica Aldrich — researcher profile on SciRah

h-index: 19
Works: 63
Citations: 1,723

Most-cited papers

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma
M. Borad, Mia D. Champion, J. Egan, W. Liang +45 more
2014PLoS Genetics336 citations Open access
Semantic Scholar
Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities
David W. Craig, J. O'Shaughnessy, J. Kiefer, Jessica Aldrich +24 more
2012Molecular Cancer Therapeutics217 citations
Semantic Scholar
Alzheimer’s disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes
Shobana Sekar, Jacquelyn McDonald, Lori Cuyugan, Jessica Aldrich +8 more
2014Neurobiology of Aging189 citations Open access
Semantic Scholar
Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2
Heather L. Gardner, K. Sivaprakasam, N. Briones, V. Zismann +17 more
2019Communications Biology99 citations Open access
Semantic Scholar
Enrichment of PI3K-AKT–mTOR Pathway Activation in Hepatic Metastases from Breast Cancer
M. Pierobon, Corinne Ramos, Shukmei Wong, K. A. Hodge +20 more
2017Clinical Cancer Research84 citations Open access
Semantic Scholar
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes
Sheri Skerget, Daniel A. Peñaherrera, A. Chari, Sundar Jagannath +124 more
2024Nature Genetics82 citations Open access
Semantic Scholar
Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases
Zarko Manojlovic, Austin W. Christofferson, W. Liang, Jessica Aldrich +10 more
2017PLoS Genetics76 citations Open access
Semantic Scholar
Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing
W. Liang, David W. Craig, J. Carpten, M. Borad +25 more
2012PLoS ONE75 citations Open access
Semantic Scholar
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis
W. Hendricks, V. Zismann, K. Sivaprakasam, C. Legendre +23 more
2018PLoS Genetics61 citations Open access
Semantic Scholar
Extramedullary Myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease
J. Egan, K. Kortuem, Ahmet A. Kurdoglu, Tyler Izatt +10 more
2013British Journal of Haematology57 citations Open access
Semantic Scholar
Interim Analysis Of The Mmrf Commpass Trial, a Longitudinal Study In Multiple Myeloma Relating Clinical Outcomes To Genomic and Immunophenotypic Profiles
David W. Craig, W. Liang, Y. Venkata, Ahmet A. Kurdoglu +15 more
201346 citations
Semantic Scholar
A method to reduce ancestry related germline false positives in tumor only somatic variant calling
R. Halperin, J. Carpten, Zarko Manojlovic, Jessica Aldrich +14 more
2017BMC Medical Genomics40 citations Open access
Semantic Scholar
A Pilot Study Using Next-Generation Sequencing in Advanced Cancers: Feasibility and Challenges
G. Weiss, W. Liang, M. Demeure, J. Kiefer +14 more
2013PLoS ONE38 citations Open access
Semantic Scholar
Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers
M. Borad, J. Egan, Rachel M. Condjella, W. Liang +33 more
2016Scientific Reports30 citations Open access
Semantic Scholar
Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra®
T. White, S. Szelinger, J. LoBello, A. King +10 more
2021OncoTarget26 citations Open access
Semantic Scholar
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases
H. Babiker, Sara A. Byron, W. Hendricks, W. Elmquist +19 more
2018Investigational new drugs26 citations Open access
Semantic Scholar
Case report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies
Leah Zhrebker, Irene Cherni, Lara M. Gross, M. Hinshelwood +8 more
2017BMC Cancer26 citations Open access
Semantic Scholar
Long insert whole genome sequencing for copy number variant and translocation detection
W. Liang, Jessica Aldrich, W. Tembe, Ahmet A. Kurdoglu +7 more
2013Nucleic Acids Research25 citations Open access
Semantic Scholar
Interim Analysis of the Mmrf Commpass Trial: Identification of Novel Rearrangements Potentially Associated with Disease Initiation and Progression
S. Lonial, V. Yellapantula, W. Liang, Ahmet A. Kurdoglu +19 more
201420 citations Open access
Semantic Scholar
Simultaneous Characterization of Somatic Events and HPV-18 Integration in a Metastatic Cervical Carcinoma Patient Using DNA and RNA Sequencing
Winnie S. Liang, Jessica Aldrich, S. Nasser, Ahmet A. Kurdoglu +16 more
2014International Journal of Gynecologic Cancer19 citations Open access
Semantic Scholar
Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability
M. Demeure, David W. Craig, Shripad A. Sinari, Tracy M. Moses +14 more
2012Genome Medicine17 citations Open access
Semantic Scholar
Genomic Basis of Multiple Myeloma Subtypes from the MMRF CoMMpass Study
Sheri Skerget, Daniel A. Peñaherrera, A. Chari, S. Jagannath +54 more
2021medRxiv16 citations Open access
Semantic Scholar
An Integrated Framework for Reporting Clinically Relevant Biomarkers from Paired Tumor/Normal Genomic and Transcriptomic Sequencing Data In Support of Clinical Trials in Personalized Medicine
S. Nasser, Ahmet A. Kurdolgu, Tyler Izatt, Jessica Aldrich +13 more
2014Pacific Symposium on Biocomputing15 citations
Semantic Scholar
Molecular Predictors of Outcome and Drug Response in Multiple Myeloma: An Interim Analysis of the Mmrf CoMMpass Study
J. Keats, G. Speyer, Austin W. Christofferson, C. Legendre +26 more
201613 citations
Semantic Scholar
Multi‐omic molecular profiling guide’s efficacious treatment selection in refractory metastatic breast cancer: a prospective phase II clinical trial
M. Pierobon, N. Robert, D. Northfelt, M. Jahanzeb +21 more
2021Molecular Oncology12 citations Open access
Semantic Scholar
FGFR3 Mutations Are an Adverse Prognostic Factor in Patients with t(4;14)(p16;q32) Multiple Myeloma: An Mmrf Commpass Analysis
Brooks A. Benard, Austin W. Christofferson, C. Legendre, Jessica Aldrich +6 more
201710 citations
Semantic Scholar
Abstract CT325: Combination of the PARP inhibitor veliparib (ABT888) with irinotecan in patients with triple negative breast cancer: Preliminary activity and signature of response
P. LoRusso, S. Tolaney, Shukmei Wong, R. Parchment +15 more
20159 citations
Semantic Scholar
A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy
Glen J. Weiss, S. Byron, Jessica Aldrich, A. Sangal +5 more
2017PLoS ONE8 citations Open access
Semantic Scholar
Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry
E. Jiagge, P. Ulintz, Shukmei Wong, S. Mcdermott +23 more
2021Breast Cancer Research and Treatment7 citations
Semantic Scholar
Comprehensive Identification of Fusion Transcripts in Multiple Myeloma: An Mmrf Commpass Analysis
S. Nasser, Austin W. Christofferson, C. Legendre, Jessica Aldrich +6 more
20175 citations
Semantic Scholar
Interim Analysis of the MMRF CoMMpass Study: Comprehensive Characterization of Multiple Myeloma Patients at Diagnosis Reveals Distinct Molecular Subtypes and Clinical Outcomes
J. Keats, G. Speyer, Austin W. Christofferson, Kristi Stephenson +31 more
20155 citations
Semantic Scholar
Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial
P. LoRusso, A. Sekulic, J. Sosman, W. Liang +43 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Multi-omic profiling of metastatic lesions to guide treatment selection: The Side Out 2 trial experience.
M. Pierobon, N. Robert, D. Northfelt, M. Jahanzeb +16 more
20184 citations
Semantic Scholar
S3-5: Next Generation Sequencing Reveals Co-Activating Events in the MAPK and P13K/AKT Pathways in Metastatic Triple Negative Breast Cancers.
J. O'Shaughnessy, David W. Craig, J. Kiefer, Shripad A. Sinari +17 more
20114 citations
Semantic Scholar
A Molecular Analysis of Cereblon-Related Immunomodulatory Drug Resistance in Commpass Multiple Myeloma Patients
Sheri Skerget, Brooks A. Benard, Austin W. Christofferson, C. Legendre +7 more
20173 citations
Semantic Scholar
Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib
A. Bryce, M. Borad, J. Egan, Rachel M. Condjella +32 more
2016Clinical Genitourinary Cancer3 citations Open access
Semantic Scholar
Abstract 4493: Germline findings in targeted tumor sequencing using matched normal DNA
Subha Krishnan, G. Basu, Laura Gonzalez-Malerva, Thomas E. Royce +16 more
20163 citations
Semantic Scholar
Unsupervised Clustering of DNA Copy Number Profiles Identifies a High-Risk Subtype of Hyperdiploid Multiple Myeloma: An Mmrf Commpass Analysis
Austin W. Christofferson, Sheri Skerget, Jessica Aldrich, C. Legendre +6 more
2019Blood2 citations Open access
Semantic Scholar
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine melanoma by integrated comparative genomic analysis
W. Hendricks, V. Zismann, K. Sivaprakasam, C. Legendre +22 more
2017bioRxiv2 citations Open access
Semantic Scholar
Abstract 45: Detection of focal somatic copy number variants in whole genome, whole exome, and targeted next-generation sequencing data of tumor/normal pairs
Jessica Aldrich, J. Keats, W. Liang, J. Carpten +1 more
20162 citations
Semantic Scholar
ARID1A alterations in gastrointestinal cancers as therapeutic opportunities.
G. Basu, T. White, J. LoBello, Kevin R Lau +15 more
20162 citations
Semantic Scholar
Alterations in the cell cycle checkpoint pathway in breast cancer.
G. Basu, T. White, J. LoBello, Ahmet A. Kurdoglu +12 more
2015Journal of Clinical Oncology2 citations
Semantic Scholar
Abstract LB-59: Distinct pathways differentiate the CD44+ mesenchymal-like from the ALDH+ epithelial-like phenotype of triple negative breast cancer stem cells
E. Jiagge, Shukmei Wong, T. Luthur, S. Mcdermott +10 more
20142 citations
Semantic Scholar
Analysis of Sequential Patient Samples from the Mmrf Commpass Study Identifies a High Risk Progression Phenotype
Sheri Skerget, Daniel A. Peñaherrera, Jessica Aldrich, S. Nasser +11 more
2018Blood1 citations Open access
Semantic Scholar
Case report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies
Leah Zhrebker, Irene Cherni, Lara M. Gross, M. Hinshelwood +8 more
2017BMC Cancer1 citations Open access
Semantic Scholar
Abstract 5271: Optimization and detection of focal somatic copy number variants in whole genome, whole exome and panel sequencing for tumor/normal matched pairs and tumor only analysis
Jessica Aldrich, J. Keats, Austin W. Christofferson, W. Liang +3 more
20161 citations
Semantic Scholar
Abstract CT112: Implementation of CLIA enabled integrated whole genome (WGS)/exome (WES)/transcriptome (RNAseq) next-gen sequencing to identify therapeutically relevant targets in advanced cancer patients
M. Borad, J. Egan, Mia D. Champion, K. Hunt +11 more
20151 citations
Semantic Scholar
Author Correction: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes
Sheri Skerget, Daniel A. Peñaherrera, A. Chari, Sundar Jagannath +124 more
2025Nature Genetics0 citations Open access
Semantic Scholar
159 Xerna tumor microenvironment subtypes as a biomarker in lung cancer patients
M. Landers, Patrick Eimerman, Steve Mastrian, T. White +15 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Author response for "Multi‐omic molecular profiling guide’s efficacious treatment selection in refractory metastatic breast cancer: a prospective phase II clinical trial"
M. Pierobon, N. Robert, D. Northfelt, M. Jahanzeb +21 more
20210 citations Open access
Semantic Scholar

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