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Sara A. Byron · SciRah

Researcher profile · Semantic Scholar

Sara A. Byron

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Sara A. Byron — researcher profile on SciRah

h-index: 25
Works: 99
Citations: 3,041

Most-cited papers

Translating RNA sequencing into clinical diagnostics: opportunities and challenges
Sara A. Byron, K. Van Keuren-Jensen, D. Engelthaler, J. Carpten +1 more
2016Nature reviews genetics708 citations Open access
Semantic Scholar
Brivanib Alaninate, a Dual Inhibitor of Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Tyrosine Kinases, Induces Growth Inhibition in Mouse Models of Human Hepatocellular Carcinoma
H. Huynh, Van Chanh Ngo, J. Fargnoli, M. Ayers +9 more
2008Clinical Cancer Research214 citations Open access
Semantic Scholar
Toward precision medicine in glioblastoma: the promise and the challenges.
M. Prados, Sara A. Byron, N. Tran, J. Phillips +16 more
2015Neuro-Oncology208 citations Open access
Semantic Scholar
FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features
Sara A. Byron, M. Gartside, M. Powell, C. Wellens +4 more
2012PLoS ONE178 citations Open access
Semantic Scholar
Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation.
Sara A. Byron, M. Gartside, C. Wellens, M. A. Mallon +4 more
2008Cancer Research154 citations
Semantic Scholar
The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
Sara A. Byron, Huai-Bin Chen, Andreas Wortmann, D. Loch +6 more
2013Neoplasia135 citations Open access
Semantic Scholar
Loss-of-Function Fibroblast Growth Factor Receptor-2 Mutations in Melanoma
M. Gartside, Huai-Bin Chen, O. Ibrahimi, Sara A. Byron +16 more
2009Molecular Cancer Research132 citations Open access
Semantic Scholar
Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells
Sara A. Byron, K. B. Horwitz, J. Richer, C. Lange +2 more
2006British Journal of Cancer127 citations Open access
Semantic Scholar
A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium
S. Mueller, P. Jain, W. Liang, L. Kilburn +24 more
2019International Journal of Cancer108 citations Open access
Semantic Scholar
Enrichment of PI3K-AKT–mTOR Pathway Activation in Hepatic Metastases from Breast Cancer
M. Pierobon, Corinne Ramos, Shukmei Wong, K. A. Hodge +20 more
2017Clinical Cancer Research84 citations Open access
Semantic Scholar
FGFR2 as a molecular target in endometrial cancer.
Sara A. Byron, P. Pollock
2009Future Oncology68 citations
Semantic Scholar
Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma
Sara A. Byron, N. Tran, R. Halperin, J. Phillips +22 more
2017Clinical Cancer Research64 citations Open access
Semantic Scholar
XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts
N. Doudican, Sara A. Byron, P. Pollock, S. Orlow
2013Anti-Cancer Drugs54 citations Open access
Semantic Scholar
Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix
J. Kalinina, Sara A. Byron, H. Makarenkova, S. Olsen +9 more
2009Molecular and Cellular Biology52 citations Open access
Semantic Scholar
Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer
K. K. Budhraja, B. McDonald, M. D. Stephens, T. Contente-Cuomo +18 more
2023Science Translational Medicine50 citations Open access
Semantic Scholar
Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status
Sara A. Byron, D. Loch, C. Wellens, Andreas Wortmann +4 more
2012Molecular Cancer48 citations Open access
Semantic Scholar
FGFR2 mutations are rare across histologic subtypes of ovarian cancer.
Sara A. Byron, M. Gartside, C. Wellens, P. Goodfellow +3 more
2010Gynecologic Oncology47 citations Open access
Semantic Scholar
Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003
C. Kline, P. Jain, L. Kilburn, E. Bonner +24 more
2022Clinical Cancer Research45 citations Open access
Semantic Scholar
Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis
N. Dizman, Y. Lyou, N. Salgia, P. Bergerot +6 more
2020Journal for ImmunoTherapy of Cancer45 citations Open access
Semantic Scholar
Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer
Sara A. Byron, Elizabeth Min, Tanya S. Thal, G. Hostetter +5 more
2012PLoS ONE45 citations Open access
Semantic Scholar
FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study
Y. Jeske, Shamshad Ali, Sara A. Byron, Feng Gao +12 more
2017Gynecologic Oncology42 citations Open access
Semantic Scholar
A method to reduce ancestry related germline false positives in tumor only somatic variant calling
R. Halperin, J. Carpten, Zarko Manojlovic, Jessica Aldrich +14 more
2017BMC Medical Genomics40 citations Open access
Semantic Scholar
Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas
M. Berens, A. Sood, J. Barnholtz-Sloan, John F. Graf +24 more
2019PLoS ONE31 citations Open access
Semantic Scholar
Fibroblast Growth Factor Receptor Inhibition Synergizes With Paclitaxel and Doxorubicin in Endometrial Cancer Cells
Sara A. Byron, D. Loch, P. Pollock
2012International Journal of Gynecologic Cancer28 citations Open access
Semantic Scholar
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases
H. Babiker, Sara A. Byron, W. Hendricks, W. Elmquist +19 more
2018Investigational new drugs26 citations Open access
Semantic Scholar
The N 550 K / H Mutations in FGFR 2 Confer Differential Resistance to PD 173074 , Dovitinib , and Ponatinib ATP-Competitive Inhibitors 1
Sara A. Byron, Huai-Bin Chen, Andreas Wortmann, D. Loch +6 more
201324 citations
Semantic Scholar
Progesterone Receptor-B Regulation of Insulin-Like Growth Factor–Stimulated Cell Migration in Breast Cancer Cells via Insulin Receptor Substrate-2
Y. Ibrahim, Sara A. Byron, Xiao-Jiang Cui, Adrian V. Lee +1 more
2008Molecular Cancer Research21 citations Open access
Semantic Scholar
Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer
L. Packer, Samantha J. Stehbens, V. Bonazzi, J. Gunter +5 more
2019Molecular Oncology20 citations Open access
Semantic Scholar
Correction: FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features
Sara A. Byron, M. Gartside, M. Powell, C. Wellens +4 more
2012PLoS ONE20 citations Open access
Semantic Scholar
Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression
M. Blomquist, S. Ensign, F. D'Angelo, J. Phillips +15 more
2020Neuro-Oncology Advances18 citations Open access
Semantic Scholar
Identification of therapeutic targets in chordoma through comprehensive genomic and transcriptomic analyses
W. Liang, C. Dardis, A. Helland, Shobana Sekar +5 more
2018Cold Spring Harbor molecular case studies18 citations Open access
Semantic Scholar
Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples
R. Halperin, W. Liang, Sidharth Kulkarni, Erica E. Tassone +10 more
2019Frontiers in Oncology16 citations Open access
Semantic Scholar
Potential therapeutic strategies to interrupt insulin-like growth factor signaling in breast cancer.
Sara A. Byron, D. Yee
2003Seminars in Oncology16 citations
Semantic Scholar
Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
Sara A. Byron, W. Hendricks, A. Nagulapally, J. Kraveka +35 more
2021Cancer Research15 citations Open access
Semantic Scholar
An Integrated Framework for Reporting Clinically Relevant Biomarkers from Paired Tumor/Normal Genomic and Transcriptomic Sequencing Data In Support of Clinical Trials in Personalized Medicine
S. Nasser, Ahmet A. Kurdolgu, Tyler Izatt, Jessica Aldrich +13 more
2014Pacific Symposium on Biocomputing15 citations
Semantic Scholar
Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial
G. Sholler, Genevieve Bergendahl, Elizabeth C Lewis, J. Kraveka +27 more
2024Genome Medicine14 citations Open access
Semantic Scholar
Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma
A. Noll, Carrie Myers, M. Biery, Michael Meechan +17 more
2023Neoplasia14 citations Open access
Semantic Scholar
Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.
S. Sakthikumar, Manisha Warrier, Derick Whitley, Salvatore J. Facista +28 more
2023Veterinary and Comparative Oncology13 citations Open access
Semantic Scholar
Genomics-Enabled Precision Medicine for Cancer.
A. Roos, Sara A. Byron
2019Cancer treatment and research13 citations
Semantic Scholar
Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer
M. Becker, Y. Ibrahim, A. Oh, D. Fagan +7 more
2016PLoS ONE13 citations Open access
Semantic Scholar
Genomic and Transcriptomic Predictors of Response from Stereotactic Body Radiation Therapy in Patients with Oligoprogressive Renal Cell Carcinoma.
Z. Zengin, Ameish Govindarajan, N. Salgia, N. Sayegh +24 more
2023European Urology Oncology9 citations
Semantic Scholar
Analysis of fragment ends in plasma DNA from patients with cancer
Karan K. Budhraja, B. McDonald, M. D. Stephens, Tania Contente-Cuomo +18 more
2021medRxiv8 citations Open access
Semantic Scholar
Association of intra-tumoral microbiome and response to immune checkpoint inhibitors (ICIs) in patients with metastatic renal cell carcinoma (mRCC).
L. Meza, Yongwook Choi, A. Govindarajan, N. Dizman +15 more
2022Journal of Clinical Oncology5 citations
Semantic Scholar
Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.
S. Sakthikumar, Salvatore J. Facista, Derick Whitley, Sara A. Byron +8 more
2023Veterinary and Comparative Oncology4 citations Open access
Semantic Scholar
A pilot study of genomic‐guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high‐risk neuroblastoma
J. Kraveka, Elizabeth C Lewis, Genevieve Bergendahl, W. Ferguson +20 more
2022Cancer Reports4 citations Open access
Semantic Scholar
Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial
P. LoRusso, A. Sekulic, J. Sosman, W. Liang +43 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Precision medicine in recurrent glioblastoma: A feasibility trial conducted by the Ivy Foundation Early Phase Clinical Trials Consortium.
M. Prados, J. Kuhn, H. Colman, T. Cloughesy +15 more
20164 citations
Semantic Scholar
Interrogating the Human Diplome: Computational Methods, Emerging Applications, and Challenges.
Agnes P. Chan, Yongwook Choi, Aditya Rangan, Guang-Fa Zhang +7 more
2023Methods in molecular biology3 citations
Semantic Scholar
BM-15TARGETING MEK IS A NOVEL AND EFFECTIVE TREATMENT STRATEGY OF LUNG CNS METASTASIS
Kyle N. Johnson, G. Gooden, P. Gonzalez, M. Sepúlveda +9 more
20143 citations Open access
Semantic Scholar
Genomic and transcriptomic correlates of clinical benefit from immunotherapy and targeted therapy among patients with metastatic renal cell carcinoma (mRCC).
N. Salgia, N. Dizman, Y. Lyou, P. Bergerot +4 more
2020Journal of Clinical Oncology2 citations
Semantic Scholar

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