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S. Rana · SciRah

Researcher profile · Semantic Scholar

S. Rana

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S. Rana — researcher profile on SciRah

h-index: 11
Works: 14
Citations: 422

Most-cited papers

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.
N. Tewari-Singh, S. Rana, Mallikarjuna Gu, Arttatrana Pal +3 more
2009Toxicological Sciences83 citations Open access
Semantic Scholar
Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
S. Wenglowsky, Linjing Ren, K. Ahrendt, Ellen R. Laird +34 more
2011ACS Medicinal Chemistry Letters59 citations Open access
Semantic Scholar
ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models.
R. Woessner, B. Tunquist, C. Lemieux, E. Chlipala +7 more
2009Anticancer Research55 citations
Semantic Scholar
Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher species.
Kevin W. Hunt, A. Cook, R. Watts, Christopher T. Clark +22 more
2013Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system.
Allen A. Thomas, Kevin W. Hunt, M. Volgraf, R. Watts +23 more
2014Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor
P. Lee, M. WallaceEli, A. Marlow, Tammie C. Yeh +10 more
201030 citations
Semantic Scholar
Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability.
E. Hicken, Fredrik P. Marmsater, Mark C. Munson, S. Schlachter +17 more
2014ACS Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
S. Wenglowsky, Linjing Ren, J. Grina, Joshua D. Hansen +13 more
2014Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors.
Allen A. Thomas, Kevin W. Hunt, B. Newhouse, R. Watts +20 more
2014Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase.
Linjing Ren, K. Ahrendt, J. Grina, Ellen R. Laird +14 more
2012Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.
M. Volgraf, Lina Chan, Malcolm P. Huestis, Hans E. Purkey +10 more
2014Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Abstract 2514: ARRY-162, A Potent and Selective MEK 1/2 Inhibitor, Shows Enhanced Efficacy in Combination with Other Targeted Kinase Inhibitors and with Chemotherapy
R. Woessner, S. Winski, S. Rana, Deborah H. Anderson +2 more
20108 citations
Semantic Scholar
Abstract 2550: Combination of the KSP inhibitor ARRY-520 with bortezomib causes sustained tumor regressions and significantly increased time to regrowth in bortezomib sensitive and resistant models of multiple myeloma
R. Woessner, B. Tunquist, D. Walker, S. Rana +2 more
20116 citations
Semantic Scholar
Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma.
R. Woessner, B. Tunquist, April A Cox, S. Rana +2 more
20095 citations
Semantic Scholar

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