Researcher profile · Semantic Scholar

N. Khan

h-index: 15
Works: 34
Citations: 986

Most-cited papers

Mechanistic Investigation of Bone Marrow Suppression Associated with Palbociclib and its Differentiation from Cytotoxic Chemotherapies
Wen-Yue Hu, Tae Sung, B. Jessen, S. Thibault +3 more
2015Clinical Cancer Research160 citations Open access
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Cyclooxygenase-2 in human pathological disease.
A. Koki, N. Khan, B. M. Woerner, A. Dannenberg +6 more
2002Advances in Experimental Medicine and Biology136 citations
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Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing
Z. Radi, N. Khan
2005Inflammation Research117 citations
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Effects of cyclooxygenase inhibition on the gastrointestinal tract.
Z. Radi, N. Khan
2006Experimental and Toxicological Pathology108 citations
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Myocarditis in Cynomolgus Monkeys Following Treatment with Immune Checkpoint Inhibitors
Chang-Hua Ji, Marc D. Roy, J. Golas, A. Vitsky +11 more
2019Clinical Cancer Research96 citations Open access
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Liver Microvascular Injury and Thrombocytopenia of Antibody–Calicheamicin Conjugates in Cynomolgus Monkeys—Mechanism and Monitoring
M. Guffroy, Hadi Falahatpisheh, Kathleen E. Biddle, J. Kreeger +13 more
2016Clinical Cancer Research53 citations Open access
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Enzalutamide and Apalutamide: In vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model.
Chang-Hua Ji, M. Guha, X. Zhu, Jessica Whritenour +8 more
2019Chemical Research in Toxicology48 citations
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Pathophysiology of Cyclooxygenases in Cardiovascular Homeostasis
R. Sellers, Z. Radi, N. Khan
2010Veterinary Pathology-Supplement35 citations Open access
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Microphysiological systems in early stage drug development: Perspectives on current applications and future impact.
A. Kopec, R. Yokokawa, N. Khan, I. Horii +13 more
2021Journal of Toxicological Sciences33 citations Open access
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Comparative juvenile safety testing of new therapeutic candidates: relevance of laboratory animal data to children.
Tim Anderson, N. Khan, M. Tassinari, M. Hurtt
2009Journal of Toxicological Sciences30 citations Open access
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Characterization, Biomarkers, and Reversibility of a Monoclonal Antibody-induced Immune Complex Disease in Cynomolgus Monkeys (Macaca fascicularis)
J. Heyen, J. Rojko, M. Evans, Tom P. Brown +9 more
2014Toxicologic pathology (Print)28 citations
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Biology and postnatal development of organ systems of cynomolgus monkeys (Macaca fascicularis)
Xian-Tang Li, Rosemary Santos, Jan Bernal, Ding-Zhou Li +2 more
2022Journal of medical primatology22 citations Open access
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CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats
A. Sacaan, S. Thibault, Miyoun Hong, N. G. Kondegowda +12 more
2017Molecular Cancer Research20 citations Open access
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Age‐ and sex‐related changes in body weights and clinical pathology analytes in cynomolgus monkeys (Macaca Fascicularis) of Mauritius origin
Xian-Tang Li, Ding-Zhou Li, Kathleen E. Biddle, S. Portugal +4 more
2022Veterinary clinical pathology18 citations Open access
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Safety biomarker applications in drug development.
S. Schomaker, S. Ramaiah, N. Khan, J. Burkhardt
2019Journal of Toxicological Sciences17 citations Open access
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Skin wound healing in the SKH‐1 female mouse following inducible nitric oxide synthase inhibition
R. R. Bell, R. Dunstan, N. Khan
2007British Journal of Dermatology15 citations
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EXPRESSION OF CYCLOOXYGENASE (COX) -1 AND COX-2 IN HUMAN INVASIVE TRANSITIONAL CELL CARCINOMA OF THE URINARY BLADDER
Sulma I. Mohammed, R. Foster, N. Khan, A. Koki +2 more
19999 citations
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Lesions and Identification of Crystalline Precipitates of Glycoprotein IIb-IIIa Antagonists in the Rat Kidney
S. Levin, R. Friedman, E. Cortez, J. Hribar +4 more
1999Toxicologic pathology (Print)9 citations Open access
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Comparative Expression and Distribution of c-fos, Estrogen Receptorα (ERα), and p38α in the Uterus of Rats, Monkeys, and Humans
Z. Radi, N. Khan
20067 citations Open access
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Obstructive Protein Cast Nephropathy in Cynomolgus Monkeys Treated with Small Organic Molecules
R. E. Guzmán, K. Datta, N. Khan
2008Veterinary Pathology-Supplement6 citations
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Expression of COX-1, COX-2, iNOS and p38 in Human Brain with Stroke Lesions
Z. Radi, N. Khan
20085 citations Open access
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Comparative Analyses of Poly(ADP-Ribose) Polymerase Inhibitors
M. Guha, Z. Sobol, Mathew P. Martin, M. Hemkens +6 more
2022International journal of toxicology3 citations
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Comparative expression and distribution of c-fos, estrogen receptoralpha (eralpha), and p38alpha in the uterus of rats, monkeys, and humans.
Z. Radi, N. Khan
2006Toxicologic pathology (Print)3 citations
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Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury.
Payal Rana, Sanaa Khan, Seda Arat, D. Potter +1 more
2022Chemical Research in Toxicology2 citations
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Development challenges for carcinogenicity risk assessments of topical drugs.
B. Hollingshead, N. Khan, M. Schuler, Z. Radi
2022Journal of Toxicological Sciences2 citations
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Non-clinical combination toxicology studies: strategy, examples and future perspective.
A. Sacaan, Satoko Nonaka Hashida, N. Khan
2020Journal of Toxicological Sciences2 citations Open access
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Pathophysiology and human cancer risk assessment of pharmaceutical-induced thymoma in carcinogenicity studies.
Z. Radi, N. Khan
2023Toxicology and Applied Pharmacology1 citations
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Enzalutamide (ENZA) and apalutamide (APA) In vitro chemical reactivity studies and activity in a mouse drug allergy model (MDAM)
M. Guha, Chang-Hua Ji, X. Zhu, Jessica Whritenour +8 more
2019Annals of Oncology1 citations Open access
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Safety assessment of central nervous system tumors in 2-year rat carcinogenicity studies
A. Sacaan, S. Thibault, N. Khan
20190 citations
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Abstract 4597: A novel immuno-oncology approach: targeting cell-surface mesothelin with a fusion construct containing human granzyme B
Lawrence Cheung, Rasheed Tijani, N. Khan, Claire Thuning-Roberson +1 more
20170 citations
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Abstract LB-202: Liver microvascular injury and thrombocytopenia of antibody-calicheamicin conjugates: mechanism and monitoring
M. Guffroy, Hadi Falahatpisheh, Kathleen E. Biddle, J. Kreeger +12 more
20160 citations
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Evaluation of the Effects of Subchronic Oral Administration of n-Butyl Maleate in Sprague-Dawley Rats
R. R. Bell, Todd N Merriman, W. Vogel, J. M. Phillips +1 more
2007Journal of Toxicology and Environmental Health, Part A0 citations
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Characterization of cyclooxygenase-2 in human pathological disease
A. Koki, N. Khan, B. M. Woerner, A. Dannenberg +5 more
19990 citations
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Title: Mechanistic Investigation of Bone Marrow Suppression Associated with Palbociclib and Its Differentiation from Cytotoxic Chemotherapies Running Title: Mechanism of Palbociclib-induced Bone Marrow Suppression Statement of Translational Relevance
Wen Hu, Tae Sung, Bart A. Jessen, S. Thibault +4 more
0 citations
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Tae Sung

×3

A. Koki×3

Chang-Hua Ji×3

A. Vitsky×3

M. Guffroy×3

Kathleen E. Biddle×3

M. Guha×3

J. Burkhardt×3