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D. Weiner · SciRah

Researcher profile · Semantic Scholar

D. Weiner

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D. Weiner — researcher profile on SciRah

h-index: 79
Works: 546
Citations: 24K

Most-cited papers

DNA vaccines: prime time is now
E. Gary, D. Weiner
2020Current Opinion in Immunology168 citations Open access
Semantic Scholar
Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy
R. Somasundaram, Thomas Connelly, R. Choi, Hyeree Choi +53 more
2021Nature Communications159 citations Open access
Semantic Scholar
Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers.
P. Tebas, K. Kraynyak, Ami Patel, J. Maslow +17 more
2019Journal of Infectious Diseases96 citations
Semantic Scholar
A Synthetic DNA, multi-neoantigen vaccine drives predominately MHC class I CD8+ T-cell responses, impacting tumor challenge
Elizabeth K. Duperret, A. Perales-Puchalt, R. Stoltz, G. H. Hiranjith +5 more
2019Cancer immunology research95 citations Open access
Semantic Scholar
COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions
Opeyemi S Adeniji, L. Giron, M. Purwar, Netanel Zilberstein +12 more
2021mBio77 citations Open access
Semantic Scholar
In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies
Ami Patel, M. Bah, D. Weiner
2020BioDrugs68 citations Open access
Semantic Scholar
Intradermal-delivered DNA vaccine provides anamnestic protection in a rhesus macaque SARS-CoV-2 challenge model
Ami Patel, Jewell N. Walters, E. Reuschel, K. Schultheis +36 more
2020bioRxiv62 citations Open access
Semantic Scholar
SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients
Susanne N. Walker, Neethu Chokkalingam, E. Reuschel, M. Purwar +14 more
2020Journal of Clinical Microbiology57 citations Open access
Semantic Scholar
Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection
H. Daniell, Smruti K Nair, N. Esmaeili, G. Wakade +22 more
2021Molecular Therapy53 citations Open access
Semantic Scholar
Durability of response to VGX-3100 treatment of HPV16/18 positive cervical HSIL
P. Bhuyan, M. Dallas, K. Kraynyak, Timothy A. Herring +5 more
2020Human Vaccines & Immunotherapeutics53 citations Open access
Semantic Scholar
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne N. Walker +19 more
2020Advancement of science51 citations Open access
Semantic Scholar
Protective immunity by an engineered DNA vaccine for Mayaro virus
Hyeree Choi, S. Kudchodkar, E. Reuschel, Kanika Asija +13 more
2019PLoS Neglected Tropical Diseases47 citations Open access
Semantic Scholar
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus
Rianne N. Esquivel, Ami Patel, S. Kudchodkar, Daniel H. Park +20 more
2019Molecular Therapy47 citations Open access
Semantic Scholar
INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants
V. Andrade, A. Christensen-Quick, J. Agnes, J. Tur +20 more
2021npj Vaccines46 citations Open access
Semantic Scholar
Robust antibody and cellular responses induced by DNA-only vaccination for HIV.
S. De Rosa, S. Edupuganti, Yun-Da Huang, Xue Han +23 more
2020JCI Insight41 citations Open access
Semantic Scholar
In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity.
Megan C. Wise, Ziyang Xu, Edgar Tello-Ruiz, Charles Beck +18 more
2019Journal of Clinical Investigation41 citations Open access
Semantic Scholar
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors
R. Vonderheide, K. Kraynyak, A. Shields, A. McRee +13 more
2021Journal for ImmunoTherapy of Cancer40 citations Open access
Semantic Scholar
Establishment of a pig influenza challenge model for evaluation of monoclonal antibody delivery platforms
Adam Mcnee, Trevor R. F. Smith, B. Holzer, Becky Clark +22 more
2020Journal of Immunology39 citations Open access
Semantic Scholar
DNA-encoded bispecific T cell engagers and antibodies present long-term antitumor activity.
A. Perales-Puchalt, Elizabeth K. Duperret, Xue Yang, Patricia Hernández +8 more
2019JCI Insight39 citations Open access
Semantic Scholar
Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases
Ziyang Xu, Ami Patel, Nicholas J. Tursi, Xi-Zhou Zhu +3 more
2020Frontiers in Medical Technology36 citations Open access
Semantic Scholar
CHEMICAL and STRUCTURAL APPROACHES to RATIONAL DRUG DESIGN
D. Weiner, W. V. Williams
202030 citations
Semantic Scholar
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2
Elizabeth M. Parzych, Jianqiu Du, A. Ali, K. Schultheis +28 more
2022Nature Communications27 citations Open access
Semantic Scholar
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection
K. M. Konrath, K. Liaw, Yuan-Han Wu, Xi-Zhou Zhu +25 more
2022Cell Reports27 citations Open access
Semantic Scholar
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo
E. Gary, Nicholas J. Tursi, B. Warner, Elizabeth M. Parzych +11 more
2022Cell Reports Medicine25 citations Open access
Semantic Scholar
Immune Therapy Targeting E6/E7 Oncogenes of Human Papillomavirus Type 6 (HPV-6) Reduces or Eliminates the Need for Surgical Intervention in the Treatment of HPV-6 Associated Recurrent Respiratory Papillomatosis
C. Aggarwal, R. Cohen, M. Morrow, K. Kraynyak +14 more
2020Vaccines25 citations Open access
Semantic Scholar
Intradermal Synthetic DNA Vaccination Generates Leishmania-Specific T Cells in the Skin and Protection against Leishmania major
Lumena Louis, M. Clark, Megan C. Wise, Nelson D. Glennie +5 more
2019Infection and Immunity25 citations Open access
Semantic Scholar
Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection
Elizabeth M. Parzych, S. Gulati, Bo Zheng, M. Bah +9 more
2021mBio24 citations Open access
Semantic Scholar
A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus
Hyeree Choi, S. Kudchodkar, Michelle Ho, E. Reuschel +10 more
2020PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
IFNL3-adjuvanted HCV DNA vaccine reduces regulatory T-cell frequency and increases virus-specific T-cell responses.
J. Han, P. Sung, Seon-Hui Hong, Hoyoung Lee +10 more
2020Journal of Hepatology24 citations
Semantic Scholar
A DNA-launched nanoparticle vaccine elicits CD8+ T-cell immunity to promote in vivo tumor control
Ziyang Xu, Neethu Chokkalingam, Edgar Tello-Ruiz, Megan C. Wise +9 more
2020Cancer immunology research24 citations Open access
Semantic Scholar
Multivalent in vivo delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape
Daniel H. Park, K. Liaw, Pratik S. Bhojnagarwala, Xi-Zhou Zhu +11 more
2023Molecular Therapy: Oncolytics23 citations Open access
Semantic Scholar
Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
Opeyemi S Adeniji, L. Kuri-Cervantes, Chen-Fei Yu, Ziyang Xu +13 more
2021PLoS Pathogens23 citations Open access
Semantic Scholar
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens
E. Gary, B. Warner, Elizabeth M. Parzych, B. Griffin +23 more
2021iScience22 citations Open access
Semantic Scholar
Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model
Ami Patel, Jewell N. Walters, E. Reuschel, K. Schultheis +38 more
2021Cell Reports Medicine22 citations Open access
Semantic Scholar
Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP® DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults
S. Edupuganti, S. De Rosa, M. Elizaga, Yi-Wen Lu +20 more
2020Vaccines22 citations Open access
Semantic Scholar
In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme
Pratik S. Bhojnagarwala, Ryan P. O'Connell, Daniel H. Park, K. Liaw +6 more
2022Molecular Therapy: Oncolytics19 citations Open access
Semantic Scholar
Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations
Ziyang Xu, Neethu Chokkalingam, Edgar Tello-Ruiz, Susanne N. Walker +2 more
2020iScience19 citations Open access
Semantic Scholar
A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy
D. Bordoloi, Pratik S. Bhojnagarwala, A. Perales-Puchalt, Abhijeet J. Kulkarni +7 more
2022JCI Insight17 citations Open access
Semantic Scholar
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2
Pratima Saini, Opeyemi S Adeniji, D. Bordoloi, Jennifer D. Kinslow +15 more
2023mBio16 citations Open access
Semantic Scholar
Multivalent DNA Vaccines as a Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses
Jingjing Jiang, S. Ramos, Preeti Bangalore, Dustin Elwood +13 more
2021Viruses16 citations Open access
Semantic Scholar
A synthetic DNA vaccine targeting multiple neoantigens induced robust, T cell immunity and controls growth of heterogenous, multi-focal lung and ovarian tumors in mice
Pratik S. Bhojnagarwala, A. Perales-Puchalt, Neil Cooch, N. Sardesai +1 more
202116 citations Open access
Semantic Scholar
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates
Jewell N. Walters, Blake Schouest, Ami Patel, E. Reuschel +20 more
2021bioRxiv15 citations Open access
Semantic Scholar
INO-5401 and INO-9012 delivered intramuscularly (IM) with electroporation (EP) in combination with cemiplimab (REGN2810) in newly diagnosed glioblastoma (GBM): Interim results.
D. Reardon, S. Brem, A. Desai, S. Bagley +16 more
202014 citations
Semantic Scholar
Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus
Ami Patel, E. Reuschel, Ziyang Xu, F. Zaidi +19 more
2021JCI Insight13 citations Open access
Semantic Scholar
Simplifying checkpoint inhibitor delivery through in vivo generation of synthetic DNA-encoded monoclonal antibodies (DMAbs)
A. Perales-Puchalt, Elizabeth K. Duperret, K. Muthumani, D. Weiner
2019OncoTarget13 citations Open access
Semantic Scholar
Gene-encoded nanoparticle vaccine platforms for in vivo assembly of multimeric antigen to promote adaptive immunity
Nicholas J. Tursi, Ziyang Xu, Daniel W. Kulp, D. Weiner
2023Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology12 citations Open access
Semantic Scholar
Immunotherapy of prostate cancer using novel synthetic DNA vaccines targeting multiple tumor antigens
D. Bordoloi, Peng Xiao, Hyeree Choi, Michelle Ho +7 more
2021Genes & cancer12 citations Open access
Semantic Scholar
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge
E. Gary, Nicholas J. Tursi, B. Warner, Gina Cuismano +19 more
2023Frontiers in Immunology11 citations Open access
Semantic Scholar
Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection
J. Jacobson, D. Zahrieh, C. Strand, M. Cruz-Correa +16 more
2022Cancer Prevention Research11 citations Open access
Semantic Scholar
Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine
Ghiabe H. Guibinga, B. Sahay, Heather Brown, Neil Cooch +12 more
2020Human Vaccines & Immunotherapeutics11 citations Open access
Semantic Scholar

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