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Daniel W. Kulp · SciRah

Researcher profile · Semantic Scholar

Daniel W. Kulp

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Daniel W. Kulp — researcher profile on SciRah

h-index: 40
Works: 91
Citations: 7,897

Most-cited papers

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
J. Jardine, Daniel W. Kulp, C. Havenar-Daughton, A. Sarkar +18 more
2016Science446 citations Open access
Semantic Scholar
Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
J. Jardine, T. Ota, D. Sok, M. Pauthner +14 more
2015Science420 citations Open access
Semantic Scholar
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
Kimberly M. Cirelli, D. Carnathan, B. Nogal, Jacob T. Martin +30 more
2018bioRxiv405 citations Open access
Semantic Scholar
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
J. Steichen, Daniel W. Kulp, T. Tokatlian, A. Escolano +25 more
2016Immunity395 citations Open access
Semantic Scholar
Salt Bridges: Geometrically Specific, Designable Interactions
Jason E. Donald, Daniel W. Kulp, W. DeGrado
2011Proteins: Structure, Function, and Bioinformatics383 citations Open access
Semantic Scholar
Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens
R. Abbott, J. Lee, Sergey Menis, Patrick D. Skog +9 more
2017Immunity324 citations Open access
Semantic Scholar
Sequential Immunization Elicits Broadly Neutralizing anti-HIV-1 Antibodies in Ig Knock-in Mice
A. Escolano, J. Steichen, P. Dosenovic, Daniel W. Kulp +18 more
2016Cell318 citations Open access
Semantic Scholar
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches
M. Pauthner, C. Havenar-Daughton, D. Sok, Joseph P. Nkolola +33 more
2017Immunity302 citations Open access
Semantic Scholar
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
T. Tokatlian, Benjamin J. Read, Christopher A. Jones, Daniel W. Kulp +12 more
2018Science281 citations Open access
Semantic Scholar
Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knock-In Mice
P. Dosenovic, L. von Boehmer, A. Escolano, J. Jardine +20 more
2015Cell279 citations Open access
Semantic Scholar
Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies
Bryan S. Briney, D. Sok, J. Jardine, Daniel W. Kulp +23 more
2016Cell270 citations Open access
Semantic Scholar
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
J. Steichen, Ying-Cing Lin, C. Havenar-Daughton, Simone Pecetta +27 more
2019Science249 citations Open access
Semantic Scholar
Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies
L. McCoy, M. V. van Gils, G. Ozorowski, Terrence Messmer +15 more
2016Cell Reports243 citations Open access
Semantic Scholar
Engineered immunogen binding to alum adjuvant enhances humoral immunity
Tyson J. Moyer, Y. Kato, Wuhbet D. Abraham, Jason Y. H. Chang +18 more
2020Nature Medicine240 citations Open access
Semantic Scholar
Global site-specific N-glycosylation analysis of HIV envelope glycoprotein
Liwei Cao, J. Diedrich, Daniel W. Kulp, M. Pauthner +15 more
2017Nature Communications214 citations Open access
Semantic Scholar
Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV
D. Sok, K. Doores, Bryan S. Briney, Khoa Le +11 more
2014Science Translational Medicine194 citations Open access
Semantic Scholar
Generalized Fragment Picking in Rosetta: Design, Protocols and Applications
D. Gront, Daniel W. Kulp, R. Vernon, C. Strauss +1 more
2011PLoS ONE189 citations Open access
Semantic Scholar
Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination
Archana V. Boopathy, Anasuya Mandal, Daniel W. Kulp, Sergey Menis +9 more
2019Proceedings of the National Academy of Sciences of the United States of America175 citations Open access
Semantic Scholar
Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice
D. Sok, Bryan S. Briney, J. Jardine, Daniel W. Kulp +15 more
2016Science172 citations Open access
Semantic Scholar
Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers
M. Pauthner, Joseph P. Nkolola, C. Havenar-Daughton, B. Murrell +27 more
2019Immunity159 citations Open access
Semantic Scholar
Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site
E. Crooks, T. Tong, B. Chakrabarti, K. Narayan +22 more
2015PLoS Pathogens158 citations Open access
Semantic Scholar
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding
Daniel W. Kulp, J. Steichen, M. Pauthner, Xiao-Zhen Hu +17 more
2017Nature Communications142 citations Open access
Semantic Scholar
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen
C. Havenar-Daughton, A. Sarkar, Daniel W. Kulp, Laura Toy +19 more
2018Science Translational Medicine133 citations Open access
Semantic Scholar
Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies
Laura K. Pritchard, D. Spencer, L. Royle, Camille Bonomelli +13 more
2015Nature Communications131 citations Open access
Semantic Scholar
Design of a switchable eliminase
I. Korendovych, Daniel W. Kulp, Yibing Wu, Hong Cheng +2 more
2011Proceedings of the National Academy of Sciences of the United States of America119 citations Open access
Semantic Scholar
Advances in structure-based vaccine design
Daniel W. Kulp, W. Schief
2013Current Opinion in Virology105 citations Open access
Semantic Scholar
Altering the O2-Dependent Reactivity of de novo Due Ferri Proteins
A. Reig, M. M. Pires, Rae Ana Snyder, Yibing Wu +7 more
2012Nature Chemistry104 citations Open access
Semantic Scholar
Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation
Brian C. Smith, Eric S. Underbakke, Daniel W. Kulp, W. Schief +1 more
2013Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Small-molecule inhibitors of integrin α2β1 that prevent pathological thrombus formation via an allosteric mechanism
Meredith W. Miller, Sandeep Basra, Daniel W. Kulp, P. Billings +7 more
2009Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Consensus motif for integrin transmembrane helix association
B. Berger, Daniel W. Kulp, Lisa M. Span, Jessica L. DeGrado +4 more
2009Proceedings of the National Academy of Sciences of the United States of America83 citations Open access
Semantic Scholar
Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes
T. Tokatlian, Daniel W. Kulp, Andrew A. Mutafyan, Christopher A. Jones +9 more
2018Scientific Reports82 citations Open access
Semantic Scholar
The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions
Shao-Qing Zhang, Daniel W. Kulp, Chaim A. Schramm, M. Mravic +2 more
2015Structure81 citations Open access
Semantic Scholar
Intradermal-delivered DNA vaccine provides anamnestic protection in a rhesus macaque SARS-CoV-2 challenge model
Ami Patel, Jewell N. Walters, E. Reuschel, K. Schultheis +36 more
2020bioRxiv62 citations Open access
Semantic Scholar
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice
C. Cottrell, Xiao-Zhen Hu, J. Lee, Patrick D. Skog +33 more
2024Science Translational Medicine60 citations
Semantic Scholar
SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients
Susanne N. Walker, Neethu Chokkalingam, E. Reuschel, M. Purwar +14 more
2020Journal of Clinical Microbiology57 citations Open access
Semantic Scholar
Conformational and quantitative characterization of oritavancin-peptidoglycan complexes in whole cells of Staphylococcus aureus by in vivo 13C and 15N labeling.
Lynette Cegelski, Dirk Steuber, A. Mehta, Daniel W. Kulp +2 more
2006Journal of Molecular Biology53 citations
Semantic Scholar
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne N. Walker +19 more
2020Advancement of science51 citations Open access
Semantic Scholar
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
T. Schiffner, Ivy Phung, Rashmi Ray, A. Irimia +71 more
2024Nature Immunology49 citations Open access
Semantic Scholar
Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein
J. Bates, Christopher J. Keefer, J. Slaughter, Daniel W. Kulp +2 more
2014Virology47 citations Open access
Semantic Scholar
In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity.
Megan C. Wise, Ziyang Xu, Edgar Tello-Ruiz, Charles Beck +18 more
2019Journal of Clinical Investigation41 citations Open access
Semantic Scholar
Experimental and computational evaluation of forces directing the association of transmembrane helices.
Yao Zhang, Daniel W. Kulp, J. D. Lear, W. DeGrado
2009Journal of the American Chemical Society41 citations
Semantic Scholar
Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases
Ziyang Xu, Ami Patel, Nicholas J. Tursi, Xi-Zhou Zhu +3 more
2020Frontiers in Medical Technology36 citations Open access
Semantic Scholar
Effects of Partially Dismantling the CD4 Binding Site Glycan Fence of HIV-1 Envelope Glycoprotein Trimers on Neutralizing Antibody Induction
E. Crooks, K. Osawa, T. Tong, S. Grimley +6 more
2017Virology32 citations Open access
Semantic Scholar
Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design
Jared Adolf-Bryfogle, Jason W. Labonte, J. C. Kraft, M. Shapovalov +9 more
2021bioRxiv31 citations Open access
Semantic Scholar
Structural informatics, modeling and design with an open-source Molecular Software Library (MSL)
Daniel W. Kulp, S. Subramaniam, Jason E. Donald, B. Hannigan +3 more
2012Journal of Computational Chemistry31 citations Open access
Semantic Scholar
Erratum: Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins
A. Reig, M. M. Pires, Rae Ana Snyder, Yibing Wu +7 more
201230 citations Open access
Semantic Scholar
Protein engineering and particulate display of B-cell epitopes to facilitate development of novel vaccines.
Ziyang Xu, Daniel W. Kulp
2019Current Opinion in Immunology28 citations
Semantic Scholar
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2
Elizabeth M. Parzych, Jianqiu Du, A. Ali, K. Schultheis +28 more
2022Nature Communications27 citations Open access
Semantic Scholar
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection
K. M. Konrath, K. Liaw, Yuan-Han Wu, Xi-Zhou Zhu +25 more
2022Cell Reports27 citations Open access
Semantic Scholar
Multiple Approaches Converge on the Structure of the Integrin αIIb/β3 Transmembrane Heterodimer
Douglas G. Metcalf, Daniel W. Kulp, J. Bennett, W. DeGrado
2009Journal of Molecular Biology26 citations Open access
Semantic Scholar

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