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R. Vonderheide · SciRah

Researcher profile · Semantic Scholar

R. Vonderheide

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R. Vonderheide — researcher profile on SciRah

h-index: 94
Works: 374
Citations: 42K

Most-cited papers

Challenges and Opportunities for Pancreatic Cancer Immunotherapy
Adham S. Bear, R. Vonderheide, M. O'Hara
2020Cancer Cell574 citations Open access
Semantic Scholar
Ferroptosis of tumor neutrophils causes immune suppression in cancer
Rina Kim, Ayumi Hashimoto, N. Markosyan, V. Tyurin +19 more
2022Nature509 citations Open access
Semantic Scholar
CD40 Agonist Antibodies in Cancer Immunotherapy.
R. Vonderheide
2020Annual Review of Medicine478 citations Open access
Semantic Scholar
CD8+ T cells contribute to survival in COVID-19 patients with hematologic cancers
Erin Bange, N. Han, P. Wileyto, Justin Y. Kim +56 more
2021Nature Medicine423 citations Open access
Semantic Scholar
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
Lacey J. Padrón, Deena M. Maurer, M. O'Hara, E. O'Reilly +33 more
2022Nature Medicine325 citations Open access
Semantic Scholar
Efficacy of a small molecule inhibitor of KrasG12D in immunocompetent models of pancreatic cancer
Samantha B. Kemp, Noah Cheng, N. Markosyan, Rina Sor +19 more
2022Cancer Discovery252 citations Open access
Semantic Scholar
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Urszula N. Wasko, Jing-Jing Jiang, Tanner C. Dalton, Álvaro Curiel-García +62 more
2024Nature183 citations Open access
Semantic Scholar
Phase II Study of Maintenance Rucaparib in Patients With Platinum-Sensitive Advanced Pancreatic Cancer and a Pathogenic Germline or Somatic Variant in BRCA1, BRCA2, or PALB2
K. Reiss, R. Mick, M. O'Hara, U. Teitelbaum +13 more
2021Journal of Clinical Oncology172 citations
Semantic Scholar
Neoadjuvant selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cance
Katelyn T. Byrne, Courtney B. Betts, R. Mick, S. Sivagnanam +25 more
2021Clinical Cancer Research155 citations Open access
Semantic Scholar
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40
Fan Yang, Zhen-Qiang He, Hao Duan, Duo Zhang +14 more
2021Nature Communications142 citations Open access
Semantic Scholar
Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome
Shannon M. Liudahl, Courtney B. Betts, S. Sivagnanam, V. Morales-Oyarvide +26 more
2021Cancer Discovery140 citations Open access
Semantic Scholar
Ferroptosis of immune cells in the tumor microenvironment.
Rina Kim, Devon Taylor, R. Vonderheide, D. Gabrilovich
2023TIPS - Trends in Pharmacological Sciences132 citations Open access
Semantic Scholar
Evaluation of Cyclophosphamide/GVAX Pancreas Followed by Listeria-mesothelin (CRS-207) With or Without Nivolumab in Patients with Pancreatic Cancer
T. Tsujikawa, T. Crocenzi, J. Durham, E. Sugar +17 more
2020Clinical Cancer Research128 citations Open access
Semantic Scholar
Epigenetic and transcriptional control of the epidermal growth factor receptor (EGFR) regulates the tumor immune microenvironment in pancreatic cancer
Jin-Yang Li, Salina Yuan, Robert J. Norgard, Fangxue Yan +10 more
2020Cancer Discovery117 citations Open access
Semantic Scholar
The Cancer Surfaceome Atlas integrates genomic, functional and drug response data to identify actionable targets
Zhongyi Hu, Jiao Yuan, Meixiao Long, Jun-Jie Jiang +11 more
2021Nature Cancer112 citations Open access
Semantic Scholar
A Randomized Phase Ib/II Study of Niraparib plus Nivolumab or Ipilimumab in Patients with Platinum-Sensitive Advanced Pancreatic Cancer
K. Reiss, R. Mick, U. Teitelbaum, M. O'Hara +9 more
2022The Lancet Oncology101 citations Open access
Semantic Scholar
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
Adham S. Bear, Tatiana Blanchard, Joseph Cesare, M. Ford +15 more
2021Nature Communications99 citations Open access
Semantic Scholar
Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma
P. Shah, Alexander C. Huang, Xiao-Wei Xu, R. Orlowski +21 more
2023Cancer Research Communications77 citations Open access
Semantic Scholar
T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancers
K. Schratz, Diane A. Flasch, Christine C. Atik, Z. Cosner +10 more
2023Cancer Cell52 citations Open access
Semantic Scholar
Tumor-Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer
R. Vonderheide, Adham S. Bear
2020Frontiers in Immunology47 citations Open access
Semantic Scholar
CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer
Erin Bange, N. Han, Paul Wileyto, Justin Y. Kim +55 more
2021Research Square41 citations Open access
Semantic Scholar
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors
R. Vonderheide, K. Kraynyak, A. Shields, A. McRee +13 more
2021Journal for ImmunoTherapy of Cancer40 citations Open access
Semantic Scholar
Rates of COVID-19–Related Outcomes in Cancer Compared With Noncancer Patients
Lova Sun, Sanjna L. Surya, Anh Le, Heena Desai +12 more
2021JNCI Cancer Spectrum36 citations Open access
Semantic Scholar
Reconsidering dexamethasone for anti-emesis when combining chemotherapy and immunotherapy.
T. Janowitz, Sam O. Kleeman, R. Vonderheide
2021The Oncologist35 citations Open access
Semantic Scholar
Systematic illumination of druggable genes in cancer genomes
Jun-Jie Jiang, Jiao Yuan, Zhongyi Hu, Youyou Zhang +11 more
2022Cell Reports34 citations Open access
Semantic Scholar
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
Il-Kyu Kim, Mark S. Diamond, Salina Yuan, Samantha B. Kemp +13 more
2024Nature Communications33 citations Open access
Semantic Scholar
Cancer vaccines
John T. Schiller, D. R. Lowy, Ian H. Frazer, O. Finn +10 more
2022Cancer Cell28 citations Open access
Semantic Scholar
Site-dependent immune escape due to impaired dendritic cell cross-priming
Mark S. Diamond, Jeffrey H. Lin, R. Vonderheide
2021Cancer immunology research27 citations Open access
Semantic Scholar
Immune vulnerabilities of mutant KRAS in pancreatic cancer
Noah Cheng, R. Vonderheide
2023Trends in Cancer26 citations Open access
Semantic Scholar
Gemcitabine (Gem) and nab-paclitaxel (NP) ± nivolumab (nivo) ± CD40 agonistic monoclonal antibody APX005M (sotigalimab), in patients (Pts) with untreated metastatic pancreatic adenocarcinoma (mPDAC): Phase (Ph) 2 final results.
M. O'Hara, E. O'Reilly, R. Wolff, Z. Wainberg +16 more
202122 citations
Semantic Scholar
Advancing Cancer Interception.
S. Domchek, R. Vonderheide
2024Cancer Discovery20 citations Open access
Semantic Scholar
A stratified phase I dose escalation trial of hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma: long-term follow-up and final outcomes
A. Maity, R. Mick, R. Rengan, T. Mitchell +8 more
2021Oncoimmunology20 citations Open access
Semantic Scholar
Circulating KRAS G12D but not G12V is associated with survival in metastatic pancreatic ductal adenocarcinoma
Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long +38 more
2024Nature Communications18 citations Open access
Semantic Scholar
Phase I trial of autologous cMET-directed CAR-t cells administered intravenously in patients with melanoma & breast carcinoma.
P. Shah, Alexander C. Huang, Xiao-Wei Xu, Paul J. L. Zhang +16 more
202018 citations
Semantic Scholar
Machine learning links T-cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer
Katie E. Blise, S. Sivagnanam, Courtney B. Betts, K. Betre +10 more
2024Cancer immunology research16 citations Open access
Semantic Scholar
PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer
A. Kraya, Kara N. Maxwell, Monika A. Eiva, B. Wubbenhorst +7 more
2022JCO Precision Oncology14 citations Open access
Semantic Scholar
Pivotal roles for cancer cell–intrinsic mPGES-1 and autocrine EP4 signaling in suppressing antitumor immunity
N. Markosyan, Ilkyu Kim, C. Arora, Liz Quinones-Ware +13 more
2024JCI Insight13 citations Open access
Semantic Scholar
Accrual of Black participants to cancer clinical trials following a five-year prospective initiative of community outreach and engagement.
Carmen E. Guerra, Vicki Sallée, W. Hwang, B. Bryant +7 more
202113 citations
Semantic Scholar
A Pilot Study of Galunisertib Plus Stereotactic Body Radiotherapy in Patients with Advanced Hepatocellular Carcinoma
K. Reiss, Max M. Wattenberg, N. Damjanov, Elizabeth Prechtel Dunphy +13 more
2020Molecular Cancer Therapeutics13 citations Open access
Semantic Scholar
Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer
Katie E. Blise, S. Sivagnanam, Courtney B. Betts, K. Betre +10 more
2023bioRxiv10 citations Open access
Semantic Scholar
Rates of COVID-19-related Outcomes in Cancer compared to non-Cancer Patients
Lova Sun, Sanjna L. Surya, Anh Le, Heena Desai +12 more
2020medRxiv10 citations Open access
Semantic Scholar
Combining Radiation with Immunotherapy: The University of Pennsylvania Experience.
Leo Y. Luo, M. O'Hara, T. Mitchell, R. Vonderheide +3 more
2020Seminars in Radiation Oncology9 citations
Semantic Scholar
Right to Try Requests and Oncologists' Gatekeeping Obligations.
Holly Fernandez Lynch, A. Sarpatwari, R. Vonderheide, Patricia J. Zettler
2020Journal of Clinical Oncology9 citations Open access
Semantic Scholar
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma
Urszula N. Wasko, Jing-Jing Jiang, Álvaro Curiel-García, Yingyun Wang +43 more
2023bioRxiv7 citations Open access
Semantic Scholar
Feasibility and utility of synthetic control arms derived from real-world data to support clinical development.
Jaclyn P Lyman, A. Doucette, Binbin Zheng-Lin, Christopher R. Cabanski +10 more
2022Journal of Clinical Oncology6 citations
Semantic Scholar
Clinical and translational results from a phase 1 trial of gemcitabine/nab-paclitaxel with nivolumab/ipilimumab or hydroxychloroquine/ipilimumab in untreated metastatic pancreatic adenocarcinoma
Eileen M. O'Reilly, Christopher R. Cabanski, Jaclyn P Lyman, Z. Wainberg +19 more
2026Journal for ImmunoTherapy of Cancer5 citations Open access
Semantic Scholar
Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Urszula N. Wasko, Jing-Jing Jiang, Tanner C. Dalton, Álvaro Curiel-García +62 more
2024Nature4 citations
Semantic Scholar
Cancer vaccines are back, revitalized.
R. Vonderheide
2023i Medicina4 citations Open access
Semantic Scholar
A unique window of opportunity for practical reform of cancer clinical trials
D. Vogl, Vicki Sallée, M. Hendricks, Colleen Redlinger Tabery +5 more
2021Cancer4 citations Open access
Semantic Scholar
Alternatives to Perpetual Chemotherapy for Metastatic Pancreatic Cancer
K. Reiss, R. Vonderheide
2021Clinical Cancer Research4 citations
Semantic Scholar

Frequent co-authors

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M. O'Hara×8
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M. O'Hara — researcher profile on SciRah
E. Wherry×7
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E. Wherry — researcher profile on SciRah
R. Mick×7
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R. Mick — researcher profile on SciRah
Alexander C. Huang×6
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Alexander C. Huang — researcher profile on SciRah

Kara N. Maxwell

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Kara N. Maxwell — researcher profile on SciRah

Jaclyn P Lyman×5

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Jaclyn P Lyman — researcher profile on SciRah

Christopher R. Cabanski×5

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Christopher R. Cabanski — researcher profile on SciRah

Katelyn T. Byrne×5

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Katelyn T. Byrne — researcher profile on SciRah

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K. Reiss — researcher profile on SciRah

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S. Domchek — researcher profile on SciRah

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L. Coussens — researcher profile on SciRah

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Erin Bange — researcher profile on SciRah