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D. Matallanas · SciRah

Researcher profile · Semantic Scholar

D. Matallanas

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D. Matallanas — researcher profile on SciRah

h-index: 35
Works: 103
Citations: 3,881

Most-cited papers

Raf family kinases: old dogs have learned new tricks.
D. Matallanas, M. Birtwistle, D. Romano, A. Zebisch +3 more
2011Genes & cancer396 citations Open access
Semantic Scholar
Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis.
Lorenzo Rinaldi, Debayan Datta, Judit Serrat, L. Morey +8 more
2016Cell Stem Cell193 citations Open access
Semantic Scholar
Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling
D. Romano, Lan K. Nguyen, D. Matallanas, M. Halasz +3 more
2014Nature Cell Biology148 citations
Semantic Scholar
Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
D. Matallanas, D. Romano, F. Al-Mulla, E. O'Neill +8 more
2011Molecules and Cells136 citations Open access
Semantic Scholar
Distinct Utilization of Effectors and Biological Outcomes Resulting from Site-Specific Ras Activation: Ras Functions in Lipid Rafts and Golgi Complex Are Dispensable for Proliferation and Transformation
D. Matallanas, Victoria Sanz-Moreno, I. Arozarena, F. Calvo +4 more
2006Molecular and Cellular Biology129 citations Open access
Semantic Scholar
Differences on the Inhibitory Specificities of H-Ras, K-Ras, and N-Ras (N17) Dominant Negative Mutants Are Related to Their Membrane Microlocalization*
D. Matallanas, I. Arozarena, M. Berciano, D. Aaronson +3 more
2003Journal of Biological Chemistry120 citations Open access
Semantic Scholar
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function
Congshan Sun, Vanessa De Mello, Abdalla D. Mohamed, H. P. Ortuste Quiroga +9 more
2017Stem Cells116 citations Open access
Semantic Scholar
Co-operation between Raf-1 and Akt pathways for the inhibition of RASSF1A-MST2-triggered apoptosis
D. Romano, D. Matallanas, G. Weitsman, C. Preisinger +2 more
2010Cancer Research106 citations Open access
Semantic Scholar
Activation of H-Ras in the Endoplasmic Reticulum by the RasGRF Family Guanine Nucleotide Exchange Factors
I. Arozarena, D. Matallanas, M. Berciano, Victoria Sanz-Moreno +5 more
2004Molecular and Cellular Biology104 citations Open access
Semantic Scholar
RASSF2 associates with and stabilises the proapoptotic kinase MST2
W. Cooper, L. Hesson, D. Matallanas, A. Dallol +4 more
2009Oncogene90 citations Open access
Semantic Scholar
RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73
Angelos Papaspyropoulos, Leanne Bradley, Asmita Thapa, C. Leung +20 more
2018Nature Communications89 citations Open access
Semantic Scholar
The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways
F. Lock, N. Underhill-Day, Thomas L. Dunwell, D. Matallanas +11 more
2010Oncogene87 citations Open access
Semantic Scholar
The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair
Emma Fallahi, Niamh A. O’Driscoll, D. Matallanas
2016Genes78 citations Open access
Semantic Scholar
VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
N. Figeac, Abdalla D. Mohamed, Congshan Sun, M. Schönfelder +14 more
2019Journal of Cell Science77 citations Open access
Semantic Scholar
HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.
Jennifer M. Farrell, C. Kelly, Jens Rauch, K. Kida +9 more
2014Journal of Proteome Research75 citations Open access
Semantic Scholar
Signalling by protein phosphatases and drug development: a systems-centred view
Leann Nguyen, D. Matallanas, D. Croucher, A. von Kriegsheim +1 more
2012The FEBS Journal68 citations Open access
Semantic Scholar
Dissecting RAF inhibitor resistance by structure-based modeling reveals ways to overcome oncogenic RAS signaling
Oleksii S. Rukhlenko, Fahimeh Khorsand, A. Krstic, Jan Rožanc +12 more
2018Cell Systems67 citations Open access
Semantic Scholar
Subcellular Localization Determines the Protective Effects of Activated ERK2 against Distinct Apoptogenic Stimuli in Myeloid Leukemia Cells*
Nuria Ajenjo, Estela Cañón, I. Sánchez-Pérez, D. Matallanas +3 more
2004Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Mammalian sterile 20-like kinases in tumor suppression: an emerging pathway.
E. O'Neill, D. Matallanas, W. Kolch
2005Cancer Research62 citations Open access
Semantic Scholar
The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells.
D. Fey, D. Matallanas, Jens Rauch, Oleksii S. Rukhlenko +1 more
2016Seminars in Cell and Developmental Biology60 citations Open access
Semantic Scholar
RASSF1A Tumour Suppressor: Target the Network for Effective Cancer Therapy
Lucía García-Gutiérrez, Stephanie McKenna, W. Kolch, D. Matallanas
2020Cancers58 citations Open access
Semantic Scholar
The Ins and Outs of RAS Effector Complexes
C. Kiel, D. Matallanas, W. Kolch
2021Biomolecules52 citations Open access
Semantic Scholar
The Rho Family GTPase Cdc42 Regulates the Activation of Ras/MAP Kinase by the Exchange Factor Ras-GRF*
I. Arozarena, D. Aaronson, D. Matallanas, Victoria Sanz +7 more
2000Journal of Biological Chemistry47 citations Open access
Semantic Scholar
A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events
Colm J. Ryan, S. Kennedy, I. Bajrami, D. Matallanas +1 more
2017bioRxiv44 citations Open access
Semantic Scholar
Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway*
J. Vaqué, J. Navascués, Y. Shiio, M. Laiho +5 more
2005Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Proteomics and phosphoproteomics for the mapping of cellular signalling networks
C. Preisinger, A. von Kriegsheim, D. Matallanas, W. Kolch
2008Proteomics43 citations
Semantic Scholar
Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia
A. Zebisch, A. Wölfler, I. Fried, O. Wolf +14 more
2012Leukemia42 citations Open access
Semantic Scholar
An Integrated Global Analysis of Compartmentalized HRAS Signaling.
T. Santra, A. Herrero, Javier Rodríguez, A. von Kriegsheim +10 more
2019Cell Reports40 citations Open access
Semantic Scholar
Nanoparticles Can Wrap Epithelial Cell Membranes and Relocate Them Across the Epithelial Cell Layer
I. Urbančič, Maja Garvas, B. Kokot, Hana Majaron +12 more
2018Nano letters (Print)39 citations Open access
Semantic Scholar
RAN GTPase is a RASSF1A effector involved in controlling microtubule organization.
A. Dallol, L. Hesson, D. Matallanas, W. Cooper +4 more
2009Current Biology39 citations Open access
Semantic Scholar
A Hippo in the ointment: MST signalling beyond the fly
D. Matallanas, D. Romano, Garth Hamilton, W. Kolch +1 more
2008Cell Cycle39 citations Open access
Semantic Scholar
RASSF1A Elicits Apoptosis through an MST2 Pathway Directing Proapoptotic Transcription by the p73 Tumor Suppressor Protein
D. Matallanas, David Romano, Karen S. Y. Yee, Katrin Meissl +6 more
2007Molecules and Cells39 citations Open access
Semantic Scholar
BAX and SMAC regulate bistable properties of the apoptotic caspase system
Stephanie McKenna, Lucía García-Gutiérrez, D. Matallanas, D. Fey
2019Scientific Reports36 citations Open access
Semantic Scholar
New druggable targets in the Ras pathway?
D. Matallanas, P. Crespo
2010Current opinion in molecular therapeutics (Print)35 citations
Semantic Scholar
Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1
M. J. Caloca, J. L. Zugaza, D. Matallanas, P. Crespo +1 more
2003EMBO Journal35 citations Open access
Semantic Scholar
One Hippo and many masters: differential regulation of the Hippo pathway in cancer.
D. Romano, D. Matallanas, Dennie T. Frederick, K. Flaherty +1 more
2014Biochemical Society Transactions34 citations
Semantic Scholar
Maintenance of Cdc42 GDP-bound State by Rho-GDI Inhibits MAP Kinase Activation by the Exchange Factor Ras-GRF
I. Arozarena, D. Matallanas, P. Crespo
2001Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis
Zivile Useckaite, Mark P. Ward, A. Trappe, Rebecca Reilly +13 more
2020Thorax32 citations Open access
Semantic Scholar
The Differential Effects of Wild-Type and Mutated K-Ras on MST2 Signaling Are Determined by K-Ras Activation Kinetics
D. Romano, H. Maccario, Carolanne Doherty, N. Quinn +2 more
2013Molecular and Cellular Biology32 citations Open access
Semantic Scholar
Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling device
Lan K. Nguyen, D. Matallanas, D. Romano, B. Kholodenko +1 more
2015Cell Cycle26 citations Open access
Semantic Scholar
Hidden Targets in RAF Signalling Pathways to Block Oncogenic RAS Signalling
A. Nolan, Nourhan Aboud, W. Kolch, D. Matallanas
2021Genes25 citations Open access
Semantic Scholar
Accurate prediction of kinase-substrate networks using knowledge graphs
V. Nováček, Gavin McGauran, D. Matallanas, Adrián Vallejo Blanco +11 more
2019bioRxiv25 citations Open access
Semantic Scholar
Genes expression profiling of alveolar macrophages exposed to non-functionalized, anionic and cationic multi-walled carbon nanotubes shows three different mechanisms of toxicity
Sara Nahle, H. Cassidy, Mélanie M Leroux, Reuben Mercier +6 more
2020Journal of Nanobiotechnology24 citations Open access
Semantic Scholar
Protein and lipid homeostasis altered in rat macrophages after exposure to metallic oxide nanoparticles
Zahra Doumandji, Ramia Safar, Mélanie Lovera-Leroux, Sara Nahle +5 more
2019Cell Biology and Toxicology24 citations Open access
Semantic Scholar
BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer
Sarah-Kim Shields, E. Conroy, T. O'grady, A. McGoldrick +13 more
2018OncoTarget24 citations Open access
Semantic Scholar
A microfluidic dual gradient generator for conducting cell-based drug combination assays.
D. Kilinc, J. Schwab, Stefano Rampini, Oshoke W. Ikpekha +7 more
2016Integrative Biology24 citations Open access
Semantic Scholar
Inhaled multi-walled carbon nanotubes differently modulate global gene and protein expression in rat lungs
Carole Seidel, V. Zhernovkov, H. Cassidy, B. Kholodenko +3 more
2020Nanotoxicology22 citations Open access
Semantic Scholar
The spatiotemporal regulation of RAS signalling.
A. Herrero, D. Matallanas, W. Kolch
2016Biochemical Society Transactions21 citations Open access
Semantic Scholar
IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway
N. Quinn, Lucía García-Gutiérrez, Carolanne Doherty, A. von Kriegsheim +3 more
2021Cells20 citations Open access
Semantic Scholar
Increased Virulence of Bloodstream Over Peripheral Isolates of P. aeruginosa Identified Through Post-transcriptional Regulation of Virulence Factors
Caitríona Hickey, B. Schaible, Scott V. Nguyen, Daniel Hurley +8 more
2018Frontiers in Cellular and Infection Microbiology19 citations Open access
Semantic Scholar

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