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G. Weitsman · SciRah

Researcher profile · Semantic Scholar

G. Weitsman

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G. Weitsman — researcher profile on SciRah

h-index: 24
Works: 73
Citations: 1,743

Most-cited papers

HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers
Bob T. Li, Flavia Michelini, S. Misale, E. Cocco +45 more
2020Cancer Discovery241 citations Open access
Semantic Scholar
Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer
Jessica J. Tao, P. Castel, N. Radosevic-Robin, Moshe Elkabets +22 more
2014Science Signaling160 citations Open access
Semantic Scholar
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation
J. Monypenny, H. Milewicz, F. Flores-Borja, G. Weitsman +22 more
2026Cell Reports124 citations
Semantic Scholar
Co-operation between Raf-1 and Akt pathways for the inhibition of RASSF1A-MST2-triggered apoptosis
D. Romano, D. Matallanas, G. Weitsman, C. Preisinger +2 more
2010Cancer Research106 citations Open access
Semantic Scholar
Estrogen Receptor-α Phosphorylated at Ser118 Is Present at the Promoters of Estrogen-Regulated Genes and Is Not Altered Due to HER-2 Overexpression
G. Weitsman, Lin Li, G. Skliris, J. Davie +6 more
200685 citations Open access
Semantic Scholar
Ado-trastuzumab emtansine in patients with HER2 amplified salivary gland cancers (SGCs): Results from a phase II basket trial.
Bob T. Li, R. Shen, M. Offin, Darren J. Buonocore +16 more
2019Journal of Clinical Oncology70 citations
Semantic Scholar
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface
J. Claus, G. Patel, Flavia Autore, A. Colomba +16 more
2018eLife62 citations Open access
Semantic Scholar
Assessment of multiple different estrogen receptor-β antibodies for their ability to immunoprecipitate under chromatin immunoprecipitation conditions
G. Weitsman, G. Skliris, K. Ung, B. Peng +3 more
2006Breast Cancer Research and Treatment60 citations
Semantic Scholar
How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology.
G. Fruhwirth, Luis P. Fernandes, G. Weitsman, G. Patel +12 more
2011ChemPhysChem55 citations
Semantic Scholar
Vitamin D enhances caspase‐dependent and ‐independent TNFα‐induced breast cancer cell death: The role of reactive oxygen species and mitochondria
G. Weitsman, A. Ravid, U. Liberman, R. Koren
2003International Journal of Cancer52 citations Open access
Semantic Scholar
From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-α kinase activity
T. Niault, I. Sobczak, Katrin Meissl, G. Weitsman +10 more
2009Journal of Cell Biology50 citations Open access
Semantic Scholar
Vitamin D Enhances Caspase‐Dependent and Independent TNF‐Induced Breast Cancer Cell Death
G. Weitsman, A. Ravid, U. Liberman, Ruth Koren
2003Annals of the New York Academy of Sciences49 citations
Semantic Scholar
Effect of Phosphorylation on EGFR Dimer Stability Probed by Single-Molecule Dynamics and FRET/FLIM
O. Coban, Laura C Zanetti-Dominguez, D. Matthews, Daniel J. Rolfe +13 more
2015Biophysical Journal46 citations Open access
Semantic Scholar
Vitamin D sensitizes breast cancer cells to the action of H2O2: mitochondria as a convergence point in the death pathway.
G. Weitsman, R. Koren, Efrat Zuck, C. Rotem +2 more
2005Free Radical Biology & Medicine46 citations
Semantic Scholar
Time-Domain Microfluidic Fluorescence Lifetime Flow Cytometry for High-Throughput Förster Resonance Energy Transfer Screening
J. Nedbal, Viput Visitkul, Elena Ortiz-Zapater, G. Weitsman +4 more
2014Cytometry Part A43 citations Open access
Semantic Scholar
Potential role of estrogen receptor α (ERα) phosphorylated at Serine118 in human breast cancer in vivo
L. Murphy, G. Weitsman, G. Skliris, E. M. Teh +8 more
200639 citations
Semantic Scholar
A Multi-Functional Imaging Approach to High-Content Protein Interaction Screening
D. Matthews, G. Fruhwirth, G. Weitsman, L. Carlin +7 more
2012PLoS ONE38 citations Open access
Semantic Scholar
HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status
G. Weitsman, P. Barber, Lan K. Nguyen, K. Lawler +12 more
2016OncoTarget34 citations Open access
Semantic Scholar
c-Met PET Imaging Detects Early-Stage Locoregional Recurrence of Basal-Like Breast Cancer
Appitha Arulappu, M. Battle, M. Eisenblaetter, G. McRobbie +10 more
2016Journal of Nuclear Medicine33 citations Open access
Semantic Scholar
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
J. Vicencio, R. Evans, R. Green, Z. An +36 more
2022Cell Death and Disease31 citations Open access
Semantic Scholar
Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha
G. Weitsman, Wineeta K. Weebadda, K. Ung, L. Murphy
2009Breast Cancer Research and Treatment27 citations
Semantic Scholar
MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition
Elena Ortiz-Zapater, Richard W. Lee, W. Owen, G. Weitsman +7 more
2017PLoS ONE26 citations Open access
Semantic Scholar
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells
Albert Bosch-Vilaró, B. Jacobs, V. Pomella, L. A. Asbagh +10 more
2016OncoTarget25 citations Open access
Semantic Scholar
Potential role of estrogen receptor alpha (ERalpha) phosphorylated at Serine118 in human breast cancer in vivo.
L. Murphy, G. Weitsman, G. Skliris, E. M. Teh +8 more
2006Journal of Steroid Biochemistry and Molecular Biology25 citations
Semantic Scholar
Shortwave Infrared Imaging Enables High-Contrast Fluorescence-Guided Surgery in Neuroblastoma
Laura Privitera, Dale J. Waterhouse, Alessandra Preziosi, I. Paraboschi +15 more
2023Cancer Research22 citations Open access
Semantic Scholar
Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor
G. Weitsman, Nick Mitchell, R. Evans, A. Cheung +19 more
2017Oncogene21 citations Open access
Semantic Scholar
Calcitriol sensitizes colon cancer cells to H2O2-induced cytotoxicity while inhibiting caspase activation.
R. Koren, Shiri Wacksberg, G. Weitsman, A. Ravid
2006Journal of Steroid Biochemistry and Molecular Biology16 citations
Semantic Scholar
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer
D. Propper, Fangfei Gao, M. Saunders, D. Sarker +12 more
2022British Journal of Cancer13 citations Open access
Semantic Scholar
HER2-HER3 Heterodimer Quantification by FRET-FLIM and Patient Subclass Analysis of the COIN Colorectal Trial
P. Barber, G. Weitsman, K. Lawler, James E. Barrett +14 more
2019Journal of the National Cancer Institute13 citations Open access
Semantic Scholar
Steady-State Acceptor Fluorescence Anisotropy Imaging under Evanescent Excitation for Visualisation of FRET at the Plasma Membrane
V. Devauges, D. Matthews, J. Aluko, J. Nedbal +7 more
2014PLoS ONE13 citations Open access
Semantic Scholar
Imaging tumour heterogeneity of the consequences of a PKCα–substrate interaction in breast cancer patients
G. Weitsman, K. Lawler, M. Kelleher, James E. Barrett +17 more
2014Biochemical Society Transactions12 citations Open access
Semantic Scholar
Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors
Robin Bofinger, G. Weitsman, R. Evans, M. Glaser +8 more
2021Nanoscale10 citations Open access
Semantic Scholar
A small molecule inhibitor of HER3: a proof-of-concept study
A. Colomba, M. Fitzek, R. George, G. Weitsman +13 more
2020Biochemical Journal10 citations Open access
Semantic Scholar
The Gray Institute open microscopes applied to radiobiology and protein interaction studies
P. Barber, Idc Tullis, M. Rowley, C. Martins +7 more
2014Biomedical optics10 citations
Semantic Scholar
The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas
Jinhai Deng, Teng Pan, Dan Wang, Yourae Hong +27 more
2024EMBO Molecular Medicine9 citations Open access
Semantic Scholar
HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models
Valentí Gómez, M. Galazi, G. Weitsman, J. Monypenny +11 more
2022Molecular Cancer Therapeutics9 citations Open access
Semantic Scholar
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation
J. Monypenny, H. Milewicz, F. Flores-Borja, G. Weitsman +22 more
2018Cell Reports9 citations Open access
Semantic Scholar
The role of p38 MAP kinase in the synergistic cytotoxic action of calcitriol and TNF-alpha in human breast cancer cells.
G. Weitsman, A. Ravid, U. Liberman, R. Koren
2004Journal of Steroid Biochemistry and Molecular Biology8 citations
Semantic Scholar
Integrating imaging, exosome and protein network rewiring information to track early tumour evolution of resistance mechanisms
F. Wong, O. Coban, G. Weitsman, T. Ng
20176 citations Open access
Semantic Scholar
HER 2-HER 3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER 2 IHC status
G. Weitsman, P. Barber, Lan K. Nguyen, K. Lawler +13 more
20166 citations
Semantic Scholar
COMBINING PROTEIN INTERACTION AND GENE PROFILING METHODS FOR PREDICTING LAPATINIB RESPONSE
G. Patel, K. Lawler, G. Weitsman, G. Fruhwirth +6 more
20116 citations
Semantic Scholar
P1.13-43 Molecular and Imaging Predictors of Response to Ado-Trastuzumab Emtansine in Patients with HER2 Mutant Lung Cancers: An Exploratory Phase 2 Trial
Bob T. Li, M. Offin, T. Hembrough, F. Cecchi +15 more
2018Journal of Thoracic Oncology4 citations Open access
Semantic Scholar
RNF144A shapes the hierarchy of cytokine signaling to provide protective immunity against influenza
B. Afzali, S. Kim, E. West, E. Nova-Lamperti +17 more
2019bioRxiv3 citations Open access
Semantic Scholar
T6 MET targeted therapy in Lung adenocarcinoma: Does ‘Resistant’ EGFR make a MET-responsive dimer?
Richard W. Lee, Elena Ortiz-Zapater, G. Weitsman, G. Fruhwirth +3 more
20153 citations Open access
Semantic Scholar
TLR9 Downregulation in Breast Cancer: Its Role in Tumor Immunity, Inflammatory Response, and Cellular Senescence
Emily Sible, G. Weitsman, Salome Amouyal, G. Roblot +12 more
2025Journal of Innate Immunity2 citations Open access
Semantic Scholar
Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development
P. Barber, R. Mustapha, Fabian Flores-Borja, Giovanna Alfano +18 more
2021medRxiv2 citations Open access
Semantic Scholar
RUNIMC: An R-based package for imaging mass cytometry data analysis and pipeline validation
L. Dolcetti, P. Barber, G. Weitsman, S. Thavaraj +6 more
2021bioRxiv2 citations Open access
Semantic Scholar
The use of exosome and immune profiling to analyze a phase 2 study on the addition of patritumab or placebo to cetuximab and a platinum agent for recurrent / metastatic head and neck cancer (R/M HNSCC) patients.
T. Ng, F. Flores-Borja, G. Alfano, P. Barber +8 more
20182 citations
Semantic Scholar
The Impact of TLR9 Expression Loss on Breast Cancer Tumor Cells
Emily Sible, G. Weitsman, Salome Amoyal, G. Roblot +11 more
2024bioRxiv1 citations Open access
Semantic Scholar
Small molecule PD-L1 inhibitor modulates expression of PD-L1 on the cell surface – a potential mechanism of blocking interaction with PD-1
G. Weitsman, Nuo-En J. Chan, J. Nedbal, P. Barber +7 more
2022European Journal of Cancer1 citations Open access
Semantic Scholar

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