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Yaakov Benenson · SciRah

Researcher profile · Semantic Scholar

Yaakov Benenson

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Yaakov Benenson — researcher profile on SciRah

h-index: 26
Works: 75
Citations: 4,719

Most-cited papers

An autonomous molecular computer for logical control of gene expression
Yaakov Benenson, Binyamin Gil, Uri Ben-Dor, R. Adar +1 more
2004Nature812 citations Open access
Semantic Scholar
Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells
Zhen Xie, Liliana Wroblewska, Laura Prochazka, Ron Weiss +1 more
2011Science732 citations
Semantic Scholar
A universal RNAi-based logic evaluator that operates in mammalian cells
Keller Rinaudo, Leonidas Bleris, Rohan Maddamsetti, Sairam Subramanian +2 more
2007Nature Biotechnology476 citations
Semantic Scholar
Programmable and autonomous computing machine made of biomolecules
Yaakov Benenson, Tamar Paz-Elizur, R. Adar, E. Keinan +2 more
2001Nature428 citations Open access
Semantic Scholar
Biomolecular computing systems: principles, progress and potential
Yaakov Benenson
2012Nature reviews genetics356 citations
Semantic Scholar
DNA molecule provides a computing machine with both data and fuel
Yaakov Benenson, R. Adar, Tamar Paz-Elizur, Z. Livneh +1 more
2003Proceedings of the National Academy of Sciences of the United States of America250 citations Open access
Semantic Scholar
Biocomputers: from test tubes to live cells
Yaakov Benenson
2009Molecular Biosystems147 citations Open access
Semantic Scholar
Rationally-designed logic integration of regulatory signals in mammalian cells
M. Leisner, Leonidas Bleris, J. Lohmueller, Zhen Xie +1 more
2010Nature Nanotechnology120 citations Open access
Semantic Scholar
Molecular Systems Biology Peer Review Process File Synthetic Incoherent Feed-forward Circuits Show Adaptation to the Amount of Their Genetic Template. Transaction Report
Leonidas Bleris, Zhen Xie, David N. Glass, Asa Adadey +2 more
118 citations
Semantic Scholar
Stochastic computing with biomolecular automata
R. Adar, Yaakov Benenson, Gregory Linshiz, Amit Rosner +2 more
2004Proc. Natl. Acad. Sci. USA103 citations Open access
Semantic Scholar
Synthetic control systems for high performance gene expression in mammalian cells
G. Lillacci, Yaakov Benenson, M. Khammash
2018Nucleic Acids Research97 citations Open access
Semantic Scholar
Bringing DNA computers to life
E. Shapiro, Yaakov Benenson
200692 citations
Semantic Scholar
RNA computers in live cells: results and prospects
Yaakov Benenson
2009Current Opinion in Biotechnology78 citations Open access
Semantic Scholar
Logic integration of mRNA signals by an RNAi-based molecular computer
Zhen Xie, S. Liu, Leonidas Bleris, Yaakov Benenson
2010Nucleic Acids Research61 citations Open access
Semantic Scholar
Large-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping
Simone Hollerer, Laetitia Papaxanthos, Anja C. Gumpinger, K. Fischer +4 more
2020Nature Communications60 citations Open access
Semantic Scholar
Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template
Leonidas Bleris, Zhen Xie, David J. Glass, Asa Adadey +2 more
2011Molecular Systems Biology56 citations Open access
Semantic Scholar
Digital switching in a biosensor circuit via programmable timing of gene availability
Nicolas Lapique, Yaakov Benenson
2014Nature Chemical Biology46 citations Open access
Semantic Scholar
Transplantation of prokaryotic two-component signaling pathways into mammalian cells
Jonathan J. Hansen, Erik Mailand, K. Swaminathan, J. Schreiber +2 more
2014Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Automated Design of Synthetic Cell Classifier Circuits Using a Two-Step Optimization Strategy.
P. Mohammadi, N. Beerenwinkel, Yaakov Benenson
2017Cell Systems45 citations Open access
Semantic Scholar
Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells
Bartolomeo Angelici, Erik Mailand, B. Haefliger, Yaakov Benenson
2016Cell Reports45 citations Open access
Semantic Scholar
Highly modular bow-tie gene circuits with programmable dynamic behavior
Laura Prochazka, Bartolomeo Angelici, Benjamin Häfliger, Yaakov Benenson
2014Nature Communications44 citations Open access
Semantic Scholar
Catalytic mechanism of Kdo8P synthase: transient kinetic studies and evaluation of a putative reaction intermediate.
P. Liang, J. Lewis, Karen S. Anderson, Amnon Kohen +3 more
1998Biochemistry39 citations
Semantic Scholar
Synthetic biology with RNA: progress report.
Yaakov Benenson
2012Current Opinion in Chemical Biology35 citations
Semantic Scholar
Artificial signaling in mammalian cells enabled by prokaryotic two-component system
Alain Mazé, Yaakov Benenson
2019Nature Chemical Biology34 citations Open access
Semantic Scholar
Rapid hierarchical assembly of medium-size DNA cassettes
Jonathan L. Schmid-Burgk, Zhen Xie, Stefan Frank, Sebastian Virreira Winter +4 more
2012Nucleic Acids Research29 citations Open access
Semantic Scholar
Synthetic gene circuits and cellular decision-making in human pluripotent stem cells
Laura Prochazka, Yaakov Benenson, P. Zandstra
201727 citations Open access
Semantic Scholar
Model‐guided combinatorial optimization of complex synthetic gene networks
J. Schreiber, Meret Arter, Nicolas Lapique, B. Haefliger +1 more
2016Molecular Systems Biology25 citations Open access
Semantic Scholar
Precision multidimensional assay for high-throughput microRNA drug discovery
B. Haefliger, Laura Prochazka, Bartolomeo Angelici, Yaakov Benenson
2016Nature Communications24 citations Open access
Semantic Scholar
Biocomputing: DNA computes a square root.
Yaakov Benenson
2011Nature Nanotechnology23 citations
Semantic Scholar
Molecular Computing Machines
Yaakov Benenson, E. Shapiro
200421 citations
Semantic Scholar
An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice
Bartolomeo Angelici, Linling Shen, J. Schreiber, A. Abraham +1 more
2021Science Translational Medicine19 citations Open access
Semantic Scholar
Genetic programs can be compressed and autonomously decompressed in live cells
Nicolas Lapique, Yaakov Benenson
2017Nature Nanotechnology17 citations Open access
Semantic Scholar
Tapping the computing power of biological molecules gives rise to tiny machines that can speak directly to living cells.
E. Shapiro, Yaakov Benenson
2006Scientific American17 citations
Semantic Scholar
Preparation and Characterization of Gel Propellants and Simulants
S. Rahimi, D. Hasan, A. Peretz, Yaakov Benenson +1 more
200117 citations
Semantic Scholar
Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells
Laura Prochazka, Y. Michaels, Charles Lau, Ross D. Jones +9 more
2022Molecular Systems Biology15 citations Open access
Semantic Scholar
Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells.
Jiten Doshi, K. Willis, A. Madurga, Christoph Stelzer +1 more
2020Cell Reports15 citations Open access
Semantic Scholar
Reverse Engineering Validation using a Benchmark Synthetic Gene Circuit in Human Cells
Taek Kang, Jacob T. White, Zhen Xie, Yaakov Benenson +2 more
2013ACS Synthetic Biology15 citations Open access
Semantic Scholar
Catalytic mechanism of KDO8P synthase: synthesis and evaluation of a putative reaction intermediate
F. D'Souza, Yaakov Benenson, T. Baasov
199715 citations
Semantic Scholar
A self-assembling amphiphilic peptide nanoparticle for the efficient entrapment of DNA cargoes up to 100 nucleotides in length.
Shabnam Tarvirdipour, Cora-Ann Schoenenberger, Yaakov Benenson, C. Palivan
2020Soft Matter14 citations Open access
Semantic Scholar
A Workflow for In Vivo Evaluation of Candidate Inputs and Outputs for Cell Classifier Gene Circuits.
Margaux Dastor, J. Schreiber, Laura Prochazka, Bartolomeo Angelici +5 more
2017ACS Synthetic Biology13 citations
Semantic Scholar
Synthetic biology of cell signaling
Jonathan J. Hansen, Yaakov Benenson
2016Natural Computing13 citations
Semantic Scholar
MicroRNA circuits for transcriptional logic.
M. Leisner, Leonidas Bleris, J. Lohmueller, Zhen Xie +1 more
2012Methods in molecular biology12 citations
Semantic Scholar
Synthetic gene circuits that selectively target RAS-driven cancers
Gabriel Senn, Leon Nissen, Yaakov Benenson
2025bioRxiv11 citations Open access
Semantic Scholar
A self-assembling peptidic platform to boost the cellular uptake and nuclear delivery of oligonucleotides.
Shabnam Tarvirdipour, Michal Skowicki, Cora-Ann Schoenenberger, L. Kapinos +3 more
2022Biomaterials Science10 citations Open access
Semantic Scholar
Multi-input biocomputer gene circuits for therapeutic application
J. Jaekel, David Schweingruber, Vasileios Cheras, Jiten Doshi +1 more
2021Current Opinion in Systems Biology10 citations
Semantic Scholar
1-(Dihydroxyphosphynyl)vinyl phosphate: The phosphonate analogue of phosphoenolpyruvate is a pH-dependent substrate of Kdo8P synthase
Yaakov Benenson, V. Belakhov, T. Baasov
19968 citations
Semantic Scholar
Recombinatorial Logic
Yaakov Benenson
2013Science5 citations
Semantic Scholar
Rational design and construction of multi-copy biomanufacturing islands in mammalian cells
R. Altamura, Jiten Doshi, Yaakov Benenson
2021Nucleic Acids Research4 citations Open access
Semantic Scholar
Targeted apoptotic immune modulator for the treatment of metastatic EGFR-positive solid tumors
Derrick Broka, Shoshana Klein, Alexei Shir, Babette Schade +25 more
2025Proceedings of the National Academy of Sciences of the United States of America3 citations Open access
Semantic Scholar
Complexity from Simple Building Blocks: Engineering Large-scale Information-processing Networks from Molecules.
Yaakov Benenson
2016Chimia (Basel)3 citations Open access
Semantic Scholar

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