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P. Perera · SciRah

Researcher profile · Semantic Scholar

P. Perera

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P. Perera — researcher profile on SciRah

h-index: 28
Works: 63
Citations: 4,339

Most-cited papers

TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages
Vladimir Toshchakov, Bryan W. Jones, P. Perera, K. Thomas +7 more
2002Nature Immunology713 citations
Semantic Scholar
CD11b/CD18 Acts in Concert with CD14 and Toll-Like Receptor (TLR) 4 to Elicit Full Lipopolysaccharide and Taxol-Inducible Gene Expression1 2 3
P. Perera, T. Mayadas, O. Takeuchi, S. Akira +3 more
2001Journal of Immunology435 citations Open access
Semantic Scholar
TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.
Vladimir Toshchakov, Bryan W. Jones, P. Perera, K. Thomas +7 more
2002Nature Immunology363 citations
Semantic Scholar
CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or taxol.
P. Perera, S. Vogel, G. Detore, A. Haziot +1 more
1997Journal of Immunology247 citations Open access
Semantic Scholar
The role of Interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use
P. Perera, J. Lichy, T. Waldmann, L. Perera
2011Microbes and infection244 citations Open access
Semantic Scholar
Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosphorylation in murine macrophages.
C. Manthey, M. Brandes, P. Perera, S. N. Vogel
1992Journal of Immunology191 citations
Semantic Scholar
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis
Z. Roberts, Nadège Goutagny, P. Perera, H. Kato +9 more
2007Journal of Experimental Medicine165 citations Open access
Semantic Scholar
Taxol provides a second signal for murine macrophage tumoricidal activity.
C. Manthey, P. Perera, C. Salkowski, S. N. Vogel
1994Journal of Immunology150 citations
Semantic Scholar
Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation.
S. Vogel, Dabney K. Johnson, P. Perera, A. Medvedev +3 more
1999Journal of Immunology146 citations
Semantic Scholar
Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes
S. Yokoyama, Nobumasa Watanabe, N. Sato, P. Perera +6 more
2009Proceedings of the National Academy of Sciences of the United States of America136 citations Open access
Semantic Scholar
Endotoxin-induced early gene expression in C3H/HeJ (Lpsd) macrophages.
C. Manthey, P. Perera, B. Henricson, Thomas A. Hamilton +2 more
1994Journal of Immunology134 citations
Semantic Scholar
CD14-mediated translocation of nuclear factor-kappa B induced by lipopolysaccharide does not require tyrosine kinase activity.
R. Delude, M. J. Fenton, R. Savedra, P. Perera +3 more
1994Journal of Biological Chemistry114 citations
Semantic Scholar
Dissociation of lipopolysaccharide (LPS)-inducible gene expression in murine macrophages pretreated with smooth LPS versus monophosphoryl lipid A
Beth E. Henricson, C. L. Manthey, P. Perera, T. Hamilton +1 more
1993Infection and Immunity105 citations Open access
Semantic Scholar
Paclitaxel (Taxol)-induced NF-kappaB translocation in murine macrophages
P. Perera, N. Qureshi, S. Vogel
1996Infection and Immunity86 citations Open access
Semantic Scholar
Chimeric Antigen Receptor Modified T cells That Target Chemokine Receptor CCR4 as a Therapeutic Modality for T-cell Malignancies
L. Perera, Mei-Li Zhang, M. Nakagawa, M. Petrus +4 more
2017American journal of hematology/oncology85 citations Open access
Semantic Scholar
The Proteasome as a Lipopolysaccharide-Binding Protein in Macrophages: Differential Effects of Proteasome Inhibition on Lipopolysaccharide-Induced Signaling Events 1
N. Qureshi, P. Perera, Jing Shen, Guo-Chi Zhang +4 more
2003Journal of Immunology83 citations Open access
Semantic Scholar
Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression.
N. Bhat, P. Perera, J. Carboni, J. Blanco +3 more
1999Journal of Immunology72 citations Open access
Semantic Scholar
Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice
Leo L. M. Poon, Y. H. Connie Leung, J. Nicholls, P. Perera +5 more
2009Journal of Immunology64 citations Open access
Semantic Scholar
Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease
S. Yokoyama, P. Perera, T. Waldmann, T. Hiroi +1 more
2012Journal of Clinical Immunology63 citations Open access
Semantic Scholar
Defective ceramide response in C3H/HeJ (Lpsd) macrophages.
S. Barber, P. Perera, S. N. Vogel
1995Journal of Immunology62 citations
Semantic Scholar
Effect of gram-negative endotoxin on levels of serum corticosterone, TNF alpha, circulating blood cells, and the survival of rats.
G. Feuerstein, J. Hallenbeck, B. Vanatta, R. Rabinovici +2 more
1990Circulatory shock60 citations
Semantic Scholar
Signal integration in lipopolysaccharide (LPS)-stimulated murine macrophages
S. Vogel, M. Hirschfeld, P. Perera
2001Journal of Endotoxin Research53 citations
Semantic Scholar
Activation of LPS-inducible genes by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid in primary murine macrophages. Dissection of signaling pathways leading to gene induction and tyrosine phosphorylation.
P. Perera, S. Barber, Lai-Ming Ching, S. N. Vogel
1994Journal of Immunology48 citations
Semantic Scholar
Construction of a BALB/c congenic mouse, C.C3H-Lpsd, that expresses the Lpsd allele: analysis of chromosome 4 markers surrounding the Lps gene
S. N. Vogel, J. Wax, P. Perera, C. Padlan +2 more
1994Infection and Immunity46 citations Open access
Semantic Scholar
TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-beta-dependent signaling in TLR4-mediated responses.
Vladimir Toshchakov, Bryan W. Jones, A. Lentschat, Aristóbolo M. Silva +9 more
2003Journal of Endotoxin Research43 citations
Semantic Scholar
Toxoplasma gondii soluble antigen induces a subset of lipopolysaccharide-inducible genes and tyrosine phosphoproteins in peritoneal macrophages
Zhen-Ying Li, C. L. Manthey, P. Perera, A. Sher +1 more
1994Infection and Immunity39 citations Open access
Semantic Scholar
Rhodopseudomonas sphaeroides lipid A derivatives block in vitro induction of tumor necrosis factor and endotoxin tolerance by smooth lipopolysaccharide and monophosphoryl lipid A
B. Henricson, P. Perera, N. Qureshi, K. Takayama +1 more
1992Infection and Immunity35 citations Open access
Semantic Scholar
Protective effect of BN 50739, a new platelet-activating factor antagonist, in endotoxin-treated rabbits.
Tian-Li Yue, M. Farhat, Reuven Rabinovici, P. Perera +2 more
1990Journal of Pharmacology and Experimental Therapeutics33 citations
Semantic Scholar
Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities
T. Merkel, P. Perera, Vanessa K Kelly, A. Verma +4 more
2010Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys
Rafal Zieliński, J. Smedley, P. Perera, P. Silvera +3 more
2010Vaccine25 citations Open access
Semantic Scholar
Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist.
P. Perera, J. Lichy, J. Mastropaolo, R. Rosse +1 more
2008European Neuropsychopharmacology25 citations
Semantic Scholar
Lipopolysaccharide and Its Analog Antagonists Display Differential Serum Factor Dependencies for Induction of Cytokine Genes in Murine Macrophages
P. Perera, N. Qureshi, W. Christ, P. Stütz +1 more
1998Infection and Immunity24 citations Open access
Semantic Scholar
Modulation of lipopolysaccharide-induced macrophage gene expression by Rhodobacter sphaeroides lipid A and SDZ 880.431
C. Manthey, P. Perera, N. Qureshi, P. Stutz +2 more
1993Infection and Immunity23 citations Open access
Semantic Scholar
A Multi-valent Vaccinia Virus-based Tuberculosis Vaccine Molecularly Adjuvanted with Interleukin-15 Induces Robust Immune Responses in Mice
P. Perera, S. Derrick, Kristopher Kolibab, Fumiki Momoi +4 more
2009Vaccine22 citations Open access
Semantic Scholar
CD14 dependent and independent signaling pathways in murine macrophages from normal and CD14 "knockout" (CD14KO) mice stimulated with LPS or taxol.
S. Vogel, P. Perera, G. Detore, N. Bhat +3 more
1998Progress in clinical and biological research21 citations
Semantic Scholar
Induction of early gene expression in murine macrophages by synthetic lipid A analogs with differing endotoxic potentials
P. Perera, C. Manthey, P. Stütz, J. Hildebrandt +1 more
1993Infection and Immunity20 citations Open access
Semantic Scholar
The serine/threonine phosphatase inhibitor, calyculin A, inhibits and dissociates macrophage responses to lipopolysaccharide.
S. Barber, P. Perera, R. McNally, S. N. Vogel
1995Journal of Immunology19 citations
Semantic Scholar
SHORT COMMUNICATION: Use of Serum‐Free, Compositionally Defined Medium for Analysis of Macrophage Differentiation In Vitro
S. N. Vogel, P. Perera, M. Hogan, Jeannine A. Majde
1988Journal of Leukocyte Biology16 citations
Semantic Scholar
Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection
T. Merkel, P. Perera, Gloria M Lee, A. Verma +4 more
2013Human Vaccines & Immunotherapeutics14 citations Open access
Semantic Scholar
TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-β-dependent signaling in TLR4-mediated responses
Vladimir Toshchakov, Bryan W. Jones, A. Lentschat, Aristóbolo M. Silva +9 more
200314 citations
Semantic Scholar
Janus Kinase Inhibitor Tofacitinib Shows Potent Efficacy in a Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS)
S. Yokoyama, P. Perera, S. Terawaki, Nobumasa Watanabe +4 more
2015Journal of Clinical Immunology11 citations Open access
Semantic Scholar
Detection and analysis of the 80‐kd lipopolysaccharide receptor in macrophages derived from Lpsn and Lpsd mice
P. Perera, Tai-Ying Chen, D. Morrison, S. N. Vogel
1992Journal of Leukocyte Biology11 citations
Semantic Scholar
LPS-inducible responses in severe combined immunodeficiency (SCID) mice
L. Falk, R. McNally, P. Perera, J. Kenny +1 more
199510 citations
Semantic Scholar
Dissection of LPS-induced signaling pathways in murine macrophages using LPS analogs, LPS mimetics, and agents unrelated to LPS.
S. Vogel, C. Manthey, P. Perera, Z.-Y. Li +1 more
1995Progress in clinical and biological research10 citations
Semantic Scholar
CD14-mediated Translocation of Nuclear Factor-& Induced by Lipopolysaccharide Does Not Require Tyrosine Kinase Activity*
Russell, DeludeSOllli, Matthew, J. +8 more
20019 citations
Semantic Scholar
Examination of macrophage cell surface antigen regulation by rIFN-γ and IFN-α/β utilizing digital imaging by a novel laser detection system. Anchored cell analysis station (ACAS) 470
M. Hogan, P. Perera, S. Vogel
19897 citations
Semantic Scholar
Inhibition of LPS-mediated cell activation in vitro and in vivo by gangliosides.
J. Mond, Kim Witherspoon, Robert K. Yu, P. Perera +1 more
1994Circulatory shock6 citations
Semantic Scholar
Noncoding-RNA-Based Therapeutics with an Emphasis on Prostatic Carcinoma—Progress and Challenges
V. Nava, P. Perera, Nirbhay Kumar, Maneesh Jain
2022Vaccines3 citations Open access
Semantic Scholar
Analysis of structure activity relationships for LPS-mimetic activities of taxane analogs in murine macrophages
P. Perera, J. Kadow, C. Fairchild, Kathy A. Johnston +1 more
19992 citations
Semantic Scholar
Identification of CD18 as a novel Taxol binding/signaling protein in murine macrophage membranes
S. Vogel, N. Bhat, J. Carboni, T. Mayadas +3 more
19992 citations Open access
Semantic Scholar

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