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P. Silvera · SciRah

Researcher profile · Semantic Scholar

P. Silvera

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P. Silvera — researcher profile on SciRah

h-index: 32
Works: 60
Citations: 3,567

Most-cited papers

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
S. Agnandji, A. Huttner, M. Zinser, P. Njuguna +54 more
2015New England Journal of Medicine421 citations Open access
Semantic Scholar
The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial
A. Huttner, Julie-Anne Dayer, S. Yerly, C. Combescure +18 more
2015Lancet. Infectious Diseases (Print)269 citations Open access
Semantic Scholar
Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques
A. Gallimore, M. Cranage, N. Cook, N. Almond +8 more
1995Nature Genetics203 citations Open access
Semantic Scholar
Control of SIV rebound through structured treatment interruptions during early infection.
F. Lori, M. Lewis, Jian-Qing Xu, G. Varga +8 more
2000Science194 citations
Semantic Scholar
Subunit Recombinant Vaccine Protects against Monkeypox1
Jean-Michel Héraud, Y. Edghill-Smith, V. Ayala, Irene Kalisz +17 more
2006Journal of Immunology138 citations Open access
Semantic Scholar
Rapid protection in a monkeypox model by a single injection of a replication-deficient vaccinia virus
P. Earl, Jeffrey L. Americo, L. Wyatt, Ondraya Espenshade +8 more
2008Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
Semantic Scholar
Interleukin-15 Increases Effector Memory CD8+ T Cells and NK Cells in Simian Immunodeficiency Virus-Infected Macaques
Yvonne M. Mueller, C. Petrovas, Paul M. Bojczuk, I. Dimitriou +7 more
2005Journal of Virology128 citations Open access
Semantic Scholar
Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge.
L. Hirao, R. Draghia-Akli, J. Prigge, Maria Yang +10 more
2011Journal of Infectious Diseases106 citations Open access
Semantic Scholar
Vaccination of Macaques with Long-Standing SIVmac251 Infection Lowers the Viral Set Point After Cessation of Antiretroviral Therapy1
E. Tryniszewska, J. Nacsa, Mark G. Lewis, P. Silvera +8 more
2002Journal of Immunology106 citations Open access
Semantic Scholar
Treatment with the Smallpox Antiviral Tecovirimat (ST-246) Alone or in Combination with ACAM2000 Vaccination Is Effective as a Postsymptomatic Therapy for Monkeypox Virus Infection
Aklile Berhanu, J. Prigge, P. Silvera, Kady M. Honeychurch +2 more
2015Antimicrobial Agents and Chemotherapy97 citations Open access
Semantic Scholar
A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge
G. Buchman, M. E. Cohen, Yuhong Xiao, N. Richardson-Harman +6 more
2010Vaccine95 citations Open access
Semantic Scholar
Co-administration of Tecovirimat and ACAM2000™ in Non-human Primates: Effect of Tecovirimat Treatment on ACAM2000 Immunogenicity and Efficacy Versus Lethal Monkeypox Virus Challenge.
Andrew T. Russo, Aklile Berhanu, C. Bigger, J. Prigge +3 more
2019Vaccine90 citations Open access
Semantic Scholar
Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid
J. Boyer, T. Robinson, Michele A. Kutzler, G. Vansant +14 more
2007Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Immunization with class I human histocompatibility leukocyte antigen can protect macaques against challenge infection with SIVmac‐32H
W. Chan, Angela Rodgers, C. Grief, N. Almond +7 more
1995AIDS (London)82 citations
Semantic Scholar
Outcome of Simian-Human Immunodeficiency Virus Strain 89.6p Challenge following Vaccination of Rhesus Macaques with Human Immunodeficiency Virus Tat Protein
P. Silvera, M. Richardson, J. Greenhouse, J. Yalley-Ogunro +6 more
2002Journal of Virology78 citations Open access
Semantic Scholar
Production and of monoclonal antibodies to simian immunodeficiency virus envelope glycoproteins.
K. Kent, Linda R. Gritz, G. Stallard, Martin P. Cranage +5 more
1991AIDS (London)76 citations
Semantic Scholar
Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial
M. ElSherif, Catherine Brown, D. MacKinnon-Cameron, Li Li +17 more
2017Canadian Medical Association Journal75 citations Open access
Semantic Scholar
Smallpox vaccine safety is dependent on T cells and not B cells.
S. Gordon, V. Cecchinato, V. Andresen, Jean-Michel Héraud +13 more
2011Journal of Infectious Diseases74 citations Open access
Semantic Scholar
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study
A. Huttner, S. Agnandji, C. Combescure, J. Fernandes +41 more
2018Lancet. Infectious Diseases (Print)71 citations Open access
Semantic Scholar
Molecular Smallpox Vaccine Delivered by Alphavirus Replicons Elicits Protective Immunity in Mice and Non-human Primates
J. Hooper, Anthony M Ferro, J. Golden, P. Silvera +8 more
2009Vaccine71 citations Open access
Semantic Scholar
Mechanisms of protection induced by attenuated simian immunodeficiency virus. I. Protection cannot be transferred with immune serum.
N. Almond, J. Rose, R. Sangster, P. Silvera +3 more
1997Journal of General Virology70 citations Open access
Semantic Scholar
Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial
S. Agnandji, J. Fernandes, Emmanuel B. Bache, Régis M. Obiang Mba +23 more
2017PLoS Medicine63 citations Open access
Semantic Scholar
Passive Immunization of Cynomolgus Macaques with Immune Sera or a Pool of Neutralizing Monoclonal Antibodies Failed to Protect Against Challenge with SIVmac251
K. Kent, P. Kitchin, K. Mills, M. Page +9 more
1994AIDS Research and Human Retroviruses62 citations
Semantic Scholar
Mechanisms of protection induced by attenuated simian immunodeficiency virus.
R. Stebbings, N. Almond, E. Stott, N. Berry +8 more
2002Virology58 citations Open access
Semantic Scholar
DNA/MVA HIV-1/AIDS vaccine elicits long-lived vaccinia virus-specific immunity and confers protection against a lethal monkeypox challenge
P. Nigam, P. Earl, Jeffrey L. Americo, Sunita Sharma +7 more
2007Virology55 citations Open access
Semantic Scholar
Evaluation of a candidate human immunodeficiency virus type 1 (HIV-1) vaccine in macaques: effect of vaccination with HIV-1 gp120 on subsequent challenge with heterologous simian immunodeficiency virus-HIV-1 chimeric virus.
E. Stott, N. Almond, K. Kent, B. Walker +11 more
1998Journal of General Virology51 citations Open access
Semantic Scholar
Patterns of Gene Expression in Peripheral Blood Mononuclear Cells of Rhesus Macaques Infected with SIVmac251 and Exhibiting Differential Rates of Disease Progression
M. Vahey, M. Nau, Michele L. Taubman, J. Yalley-Ogunro +2 more
2003AIDS Research and Human Retroviruses43 citations
Semantic Scholar
Mechanisms of Protection Induced by Attenuated Simian Immunodeficiency Virus II. Lymphocyte Depletion Does Not Abrogate Protection
R. Stebbings, J. Stott, N. Almond, R. Hull +9 more
1998AIDS Research and Human Retroviruses40 citations
Semantic Scholar
DNA Encoding an HIV-1 Gag/Human Lysosome-Associated Membrane Protein-1 Chimera Elicits a Broad Cellular and Humoral Immune Response in Rhesus Macaques
P. Chikhlikar, L. B. de Arruda, M. Maciel, P. Silvera +3 more
2006PLoS ONE38 citations Open access
Semantic Scholar
Protection against SIV infection in macaques by immunization with inactivated virus from the BK28 molecular clone, but not with BK28-derived recombinant env and gag proteins.
K. Mills, M. Page, W. Chan, P. Kitchin +6 more
1992Journal of medical primatology36 citations
Semantic Scholar
The development of PCR based assays for the detection and differentiation of simian immunodeficiency virus in vivo.
J. Rose, P. Silvera, B. Flanagan, P. Kitchin +1 more
1995Journal of Virological Methods35 citations
Semantic Scholar
Protection of Rhesus Monkeys against Infection with Minimally Pathogenic Simian-Human Immunodeficiency Virus: Correlations with Neutralizing Antibodies and Cytotoxic T Cells
G. Quinnan, Xiao-Fang Yu, Mark G. Lewis, Peng-Fei Zhang +10 more
2005Journal of Virology34 citations Open access
Semantic Scholar
Vaccine-induced CD4+ T cells against the simian immunodeficiency virus gag protein. Epitope specificity and relevance to protective immunity.
K. Mills, A. Barnard, M. Williams, M. Page +6 more
1991Journal of Immunology32 citations Open access
Semantic Scholar
Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease.
P. McKenna, M. Koser, Kevin R. Carlson, D. Montefiori +7 more
2007Journal of Infectious Diseases30 citations
Semantic Scholar
The use of the polymerase chain reaction for the detection of Simian immunodeficiency virus in experimentally infected macaques.
P. Kitchin, Neil Almond, Z. Szotyori, C. Fromholc +6 more
1990Journal of Virological Methods30 citations
Semantic Scholar
Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques
K. Denzler, T. Babas, Amy Rippeon, Trung P. Huynh +4 more
2011Vaccine29 citations Open access
Semantic Scholar
Protection of Rabbits and Immunodeficient Mice against Lethal Poxvirus Infections by Human Monoclonal Antibodies
Lindsay Crickard, T. Babas, S. Seth, P. Silvera +2 more
2012PLoS ONE28 citations Open access
Semantic Scholar
Fine Analysis of Humoral Antibody Response to Envelope Glycoprotein of SIV in Infected and Vaccinated Macaques
P. Silvera, B. Flanagan, K. Kent, E. Rud +6 more
1994AIDS Research and Human Retroviruses26 citations
Semantic Scholar
Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys
Rafal Zieliński, J. Smedley, P. Perera, P. Silvera +3 more
2010Vaccine25 citations Open access
Semantic Scholar
A Therapeutic SIV DNA Vaccine Elicits T-Cell Immune Responses, but No Sustained Control of Viremia in SIVmac239-Infected Rhesus Macaques
J. ZurMegede, Brigitte E. Sanders-Beer, P. Silvera, Dawn Golightly +11 more
2008AIDS Research and Human Retroviruses23 citations Open access
Semantic Scholar
Mechanisms of protection induced by live attenuated simian immunodeficiency virus
P. Silvera, A. Wade-Evans, E. Rud, R. Hull +4 more
2001Journal of medical primatology22 citations
Semantic Scholar
Comparison of DNA Vaccines Producing HIV-1 Gag and LAMP/gag Chimera In Rhesus Macaques Reveals Antigen-specific T Cell Responses With Distinct Phenotypes
A. Valentin, P. Chikhlikar, V. Patel, M. Rosati +7 more
2009Vaccine20 citations Open access
Semantic Scholar
Immunogenicity of HIV-1 IIIB and SHIV 89.6P Tat and Tat Toxoids in Rhesus Macaques: Induction of Humoral and Cellular Immune Responses
M. Richardson, Jyotika Mirchandani, P. Silvera, Emmanuel G. Régulier +9 more
2002DNA and Cell Biology20 citations
Semantic Scholar
Effect of PMPA and PMEA on the Kinetics of Viral Load in Simian Immunodeficiency Virus-Infected Macaques
P. Silvera, P. Rácz, K. Rácz, N. Bischofberger +5 more
2000AIDS Research and Human Retroviruses19 citations
Semantic Scholar
Vaccination with gp120-depleted HIV-1 plus immunostimulatory CpG oligodeoxynucleotides in incomplete Freund's adjuvant stimulates cellular and humoral immunity in rhesus macaques.
P. Silvera, J. Savary, Virginia Livingston, Jessica White +5 more
2004Vaccine13 citations
Semantic Scholar
T-Cell Receptor Excision Circles (TREC) in SHIV 89.6p and SIVmac251 Models of HIV-1 Infection
M. Richardson, A. Sverstiuk, P. Silvera, J. Greenhouse +5 more
2004DNA and Cell Biology13 citations
Semantic Scholar
Immunisation of macaques with SIV env recombinants: specificity of T cell and antibody responses and evaluation of protective efficacy.
K. Mills, M. Page, P. Kitchin, L. Chan +6 more
1993Journal of medical primatology12 citations
Semantic Scholar
High Attenuation and Immunogenicity of a Simian Immunodeficiency Virus Expressing a Proteolysis-resistant Inhibitor of NF-κB*
I. Quinto, Antimina Puca, J. Greenhouse, P. Silvera +9 more
2004Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Specific Proliferative T Cell Responses and Antibodies Elicited by Vaccination with Simian Immunodeficiency Virus Nef Do Not Confer Protection against Virus Challenge
Alison M. Wade-Evans, Jim Stott, Tomáš Hanke, R. Stebbings +11 more
2001AIDS Research and Human Retroviruses7 citations
Semantic Scholar
Investigating the Contribution of Drug-Metabolizing Enzymes in Drug-Drug Interactions of Dapivirine and Miconazole
G. Valicherla, Phillip W. Graebing, Junmei Zhang, R. Zheng +3 more
2021Pharmaceutics6 citations Open access
Semantic Scholar

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