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C. Francastel · SciRah

Researcher profile · Semantic Scholar

C. Francastel

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C. Francastel — researcher profile on SciRah

h-index: 32
Works: 79
Citations: 4,130

Most-cited papers

Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locus.
D. Schübeler, C. Francastel, D. Cimbora, A. Reik +2 more
2000Genes & Development336 citations Open access
Semantic Scholar
Nuclear compartmentalization and gene activity
C. Francastel, D. Schübeler, David I. K. Martin, M. Groudine
2000Nature reviews. Molecular cell biology297 citations
Semantic Scholar
A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.
C. Francastel, Mark C. Walters, M. Groudine, David I. K. Martin
1999Cell263 citations Open access
Semantic Scholar
Accumulation of small murine minor satellite transcripts leads to impaired centromeric architecture and function.
H. Bouzinba-Ségard, A. Guais, C. Francastel
2006Proceedings of the National Academy of Sciences of the United States of America229 citations Open access
Semantic Scholar
Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics
M. Brand, J. Ranish, Nicolas T. Kummer, Joan Hamilton +6 more
2004Nature Structural &Molecular Biology227 citations
Semantic Scholar
Mutations in CDCA7 and HELLS cause Immunodeficiency- Centromeric Instability-Facial Anomalies Syndrome
P. E. Thijssen, Y. Ito, G. Grillo, Jun Wang +25 more
2015Nature Communications183 citations Open access
Semantic Scholar
Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
E. Aref-Eshghi, J. Kerkhof, V. Pedro, Groupe di France +65 more
2021American Journal of Human Genetics172 citations Open access
Semantic Scholar
Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
E. Aref-Eshghi, J. Kerkhof, V. Pedro, M. Barat-Houari +64 more
2020American Journal of Human Genetics155 citations Open access
Semantic Scholar
Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation
F. Hubé, Guillaume Velasco, J. Rollin, D. Furling +1 more
2010Nucleic Acids Res.151 citations Open access
Semantic Scholar
Non-coding murine centromeric transcripts associate with and potentiate Aurora B kinase
Federica Ferri, H. Bouzinba-Ségard, Guillaume Velasco, F. Hubé +1 more
2009Nucleic Acids Research150 citations Open access
Semantic Scholar
Nuclear relocation of a transactivator subunit precedes target gene activation
C. Francastel, W. Magis, M. Groudine
2001Proceedings of the National Academy of Sciences of the United States of America148 citations Open access
Semantic Scholar
Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues
Guillaume Velasco, F. Hubé, J. Rollin, Damien Neuillet +5 more
2010Proceedings of the National Academy of Sciences of the United States of America141 citations Open access
Semantic Scholar
Long-Distance Control of Origin Choice and Replication Timing in the Human β-Globin Locus Are Independent of the Locus Control Region
D. Cimbora, D. Schübeler, A. Reik, Joan Hamilton +3 more
2000Molecular and Cellular Biology120 citations Open access
Semantic Scholar
Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids
S. Sagie, Shir Toubiana, Stella R. Hartono, Hagar Katzir +6 more
2017Nature Communications107 citations Open access
Semantic Scholar
When one is better than two: RNA with dual functions.
D. Ulveling, C. Francastel, F. Hubé
2011Biochimie102 citations Open access
Semantic Scholar
CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome
Motoko Unoki, H. Funabiki, Guillaume Velasco, C. Francastel +1 more
2018Journal of Clinical Investigation88 citations Open access
Semantic Scholar
Corrigendum: Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome
P. E. Thijssen, Y. Ito, G. Grillo, Jun Wang +25 more
2016Nature Communications86 citations Open access
Semantic Scholar
Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state
Guillaume Velasco, G. Grillo, N. Touleimat, Laure Ferry +6 more
2018Human Molecular Genetics73 citations
Semantic Scholar
Mammalian Introns: When the Junk Generates Molecular Diversity
F. Hubé, C. Francastel
2015International Journal of Molecular Sciences63 citations Open access
Semantic Scholar
Maintenance of DNA methylation: Dnmt3b joins the dance
E. Walton, C. Francastel, Guillaume Velasco
2011Epigenetics60 citations Open access
Semantic Scholar
MafG Sumoylation Is Required for Active Transcriptional Repression
H. Motohashi, F. Katsuoka, Chika Miyoshi, Y. Uchimura +4 more
2006Molecular and Cellular Biology60 citations
Semantic Scholar
Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients
Hirohisa Nitta, M. Unoki, K. Ichiyanagi, T. Kosho +7 more
2013Journal of Human Genetics57 citations
Semantic Scholar
CENP-A chromatin disassembly in stressed and senescent murine cells
Sabrine Hedouin, G. Grillo, Ivana Ivkovic, Guillaume Velasco +1 more
2017Scientific Reports56 citations Open access
Semantic Scholar
Genetic, Cellular and Clinical Features of ICF Syndrome: a French National Survey
D. Sterlin, Guillaume Velasco, D. Moshous, F. Touzot +5 more
2016Journal of Clinical Immunology55 citations
Semantic Scholar
Coding and Non-coding RNAs, the Frontier Has Never Been So Blurred
F. Hubé, C. Francastel
2018Frontiers in Genetics50 citations Open access
Semantic Scholar
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing
Sole Gatto, M. Gagliardi, Monica Franzese, S. Leppert +9 more
2017Nucleic Acids Research50 citations Open access
Semantic Scholar
BRCA1 prevents R-loop-associated centromeric instability
C. Racca, S. Britton, Sabrine Hedouin, C. Francastel +2 more
2021Cell Death and Disease48 citations Open access
Semantic Scholar
Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells
M. Tosolini, V. Brochard, P. Adenot, M. Chebrout +6 more
2018Scientific Reports42 citations Open access
Semantic Scholar
Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases
E. Walton, C. Francastel, Guillaume Velasco
2014Biology38 citations Open access
Semantic Scholar
Lymphoid-affiliated genes are associated with active histone modifications in human hematopoietic stem cells.
J. Maes, Marta Maleszewska, C. Guillemin, F. Pflumio +6 more
2008Blood38 citations
Semantic Scholar
Genetics meets DNA methylation in rare diseases
Guillaume Velasco, C. Francastel
2019Clinical Genetics35 citations
Semantic Scholar
CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats
Motoko Unoki, J. Sharif, Yuichiro Saito, Guillaume Velasco +3 more
2020Scientific Reports33 citations Open access
Semantic Scholar
Subtelomeric methylation distinguishes between subtypes of Immunodeficiency, Centromeric instability and Facial anomalies syndrome
Shir Toubiana, Guillaume Velasco, Adi Chityat, A. Kaindl +4 more
2018Human Molecular Genetics32 citations
Semantic Scholar
Identification of potentially new bifunctional RNA based on genome-wide data-mining of alternative splicing events.
D. Ulveling, C. Francastel, F. Hubé
2011Biochimie31 citations Open access
Semantic Scholar
Short intron-derived ncRNAs
F. Hubé, D. Ulveling, A. Sureau, S. Forveille +1 more
2017Nucleic Acids Research30 citations Open access
Semantic Scholar
NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity
C. Francastel, V. Poindessous-Jazat, Y. Augery-Bourget, J. Robert-Lézénès
1997Leukemia30 citations Open access
Semantic Scholar
Germline genes hypomethylation and expression define a molecular signature in peripheral blood of ICF patients: implications for diagnosis and etiology
Guillaume Velasco, E. Walton, D. Sterlin, Sabrine Hedouin +7 more
2014Orphanet Journal of Rare Diseases28 citations Open access
Semantic Scholar
DNA methylation influences human centromere positioning and function
Catalina Salinas-Luypaert, Danilo Dubocanin, R. Lee, Lorena Andrade Ruiz +18 more
2025Nature Genetics27 citations Open access
Semantic Scholar
DNA methylation in satellite repeats disorders.
C. Francastel, F. Magdinier
2019Essays in Biochemistry26 citations
Semantic Scholar
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
Andrea Scelfo, V. Barra, Nezar Abdennur, G. Spracklin +15 more
2024Journal of Cell Biology25 citations Open access
Semantic Scholar
Upregulation of CD9 expression during TPA treatment of K562 cells
F. Le Naour, C. Francastel, Michel Prenant, O. Lantz +2 more
1997Leukemia24 citations Open access
Semantic Scholar
Antisense c-jun overcomes a differentiation block in a murine erythroleukemia cell line.
C. Francastel, R. Groisman, C. Pfarr, J. Robert-Lézénès
1994Oncogene19 citations
Semantic Scholar
Preferential association of irreversibly silenced E2F-target genes with pericentromeric heterochromatin in differentiated muscle cells
Valentina Guasconi, L. Pritchard, Lauriane Fritsch, L. Mesner +3 more
2010Epigenetics18 citations Open access
Semantic Scholar
Chromatin Modifications in Hematopoietic Multipotent and Committed Progenitors Are Independent of Gene Subnuclear Positioning Relative to Repressive Compartments
C. Guillemin, Marta Maleszewska, A. Guais, J. Maes +5 more
2009Stem Cells16 citations
Semantic Scholar
c-Jun inhibits NF-E2 transcriptional activity in association with p18/maf in Friend erythroleukemia cells
C. Francastel, Y. Augery-Bourget, M. Prenant, Mark C. Walters +2 more
1997Oncogene14 citations
Semantic Scholar
Interplay between Histone and DNA Methylation Seen through Comparative Methylomes in Rare Mendelian Disorders
Guillaume Velasco, D. Ulveling, S. Rondeau, Pauline Marzin +3 more
2021International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Transcriptional regulation of the human CD9 gene: characterization of the 5'-flanking region.
F. Le Naour, M. Prenant, C. Francastel, Eric Rubinstein +2 more
1996Oncogene12 citations
Semantic Scholar
Co-induction of c-fos and junB during the latent period preceding commitment of Friend erythroleukemia cells to differentiation.
C. Francastel, Z. Mazouzi, J. Robert-Lézénès
1992Leukemia10 citations
Semantic Scholar
A new method for the identification of thousands of circular RNAs
Baptiste Bogard, C. Francastel, F. Hubé
20189 citations Open access
Semantic Scholar
Regulation of telomeric function by DNA methylation differs between humans and mice.
Shir Toubiana, Gal Larom, Riham Smoom, Robert J. Duszynski +4 more
2020Human Molecular Genetics7 citations
Semantic Scholar

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