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Z. W. Lai · SciRah

Researcher profile · Semantic Scholar

Z. W. Lai

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Z. W. Lai — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 1,804

Most-cited papers

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
Manuele Piccolis, L. Bond, M. Kampmann, P. Pulimeno +12 more
2019Molecules and Cells247 citations Open access
Semantic Scholar
Lipid droplet assembly factor-1 and seipin form a lipid droplet assembly complex
Jeeyun Chung, Xudong Wu, Talley J. Lambert, Z. W. Lai +2 more
2019Developmental Cell205 citations Open access
Semantic Scholar
Cryo–electron microscopy structure of the lipid droplet–formation protein seipin
X. Sui, H. Arlt, Kelly P. Brock, Z. W. Lai +5 more
2018bioRxiv181 citations Open access
Semantic Scholar
Emerging techniques in proteomics for probing nano-bio interactions.
Z. W. Lai, Yan Yan, F. Caruso, E. Nice
2012ACS Nano108 citations Open access
Semantic Scholar
Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice
N. Gluchowski, Katlyn R. Gabriel, Chandramohan Chitraju, R. Bronson +6 more
2019Hepatology106 citations Open access
Semantic Scholar
Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
N. Mejhert, Leena Kuruvilla, Katlyn R. Gabriel, Shane D. Elliott +8 more
2020Molecules and Cells105 citations Open access
Semantic Scholar
Identification of two pathways mediating protein targeting from ER to lipid droplets
Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet +6 more
2021bioRxiv94 citations Open access
Semantic Scholar
The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Jeeyun Chung, Joongkyu Park, Z. W. Lai, Talley J. Lambert +4 more
2021bioRxiv71 citations Open access
Semantic Scholar
MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
Vaishnavi V. Phadnis, J. Snider, Venkateshwari Varadharajan, Iyappan Ramachandiran +17 more
2023Cell Reports59 citations Open access
Semantic Scholar
Protein amino-terminal modifications and proteomic approaches for N-terminal profiling.
Z. W. Lai, Agnese Petrera, O. Schilling
2015Current Opinion in Chemical Biology57 citations
Semantic Scholar
The emerging role of the peptidome in biomarker discovery and degradome profiling
Z. W. Lai, Agnese Petrera, O. Schilling
2015Biological chemistry49 citations
Semantic Scholar
Angiotensin-converting enzyme 2 ectodomain shedding cleavage-site identification: determinants and constraints.
Z. W. Lai, Iresha Hanchapola, D. Steer, A. I. Smith
2011Biochemistry46 citations
Semantic Scholar
Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration
Constance S. V. Petit, Jane Lee, Sebastian Boland, Sharan Swarup +11 more
2020Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
Christina Jayson, H. Arlt, Alexander W. Fischer, Z. W. Lai +2 more
2018Molecular Biology of the Cell38 citations Open access
Semantic Scholar
Particles on the move: intracellular trafficking and asymmetric mitotic partitioning of nanoporous polymer particles.
Yan Yan, Z. W. Lai, R. Goode, Ji-Wei Cui +4 more
2013ACS Nano38 citations Open access
Semantic Scholar
The Identification of a Calmodulin-Binding Domain within the Cytoplasmic Tail of Angiotensin-Converting Enzyme-2
Z. W. Lai, R. Lew, M. Yarski, F. Mu +2 more
2009Endocrinology38 citations Open access
Semantic Scholar
Enrichment of protein N‐termini by charge reversal of internal peptides
Z. W. Lai, Alejandro Gomez-Auli, Eva J. Keller, Bettina Mayer +2 more
2015Proteomics29 citations
Semantic Scholar
Glycocapture‐based proteomics for secretome analysis
Z. W. Lai, Edouard C. Nice, O. Schilling
2013Proteomics28 citations
Semantic Scholar
Comprehensive Proteomic Analysis of Nitrogen-Starved Mycobacterium smegmatis Δpup Reveals the Impact of Pupylation on Nitrogen Stress Response.
Giuseppina Fascellaro, Agnese Petrera, Z. W. Lai, Paolo Nanni +6 more
2016Journal of Proteome Research25 citations Open access
Semantic Scholar
Carboxyterminal protein processing in health and disease: key actors and emerging technologies.
Agnese Petrera, Z. W. Lai, O. Schilling
2014Journal of Proteome Research25 citations
Semantic Scholar
FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice
Alisha V. Ling, Mary E. Gearing, I. Semova, Dong-Ju Shin +3 more
2018Endocrinology24 citations Open access
Semantic Scholar
A Systematic Protein Turnover Map for Decoding Protein Degradation
Romain Christiano, H. Arlt, Sonja Kabatnik, N. Mejhert +3 more
2020bioRxiv23 citations Open access
Semantic Scholar
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Nicolas W. Wieder, Juliana Coraor Fried, Choah Kim, Eriene-Heidi Sidhom +34 more
2023Cell Metabolism22 citations Open access
Semantic Scholar
Quantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines
J. Weißer, Z. W. Lai, P. Bronsert, M. Kuehs +9 more
2015BMC Genomics22 citations Open access
Semantic Scholar
Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity *
Zhihuan Li, Z. W. Lai, Romain Christiano, Felipe Gazos-Lopes +2 more
2018Molecular & Cellular Proteomics21 citations Open access
Semantic Scholar
Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) as a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini*
Z. W. Lai, J. Weißer, Lars Nilse, F. Costa +6 more
2016Molecular & Cellular Proteomics19 citations Open access
Semantic Scholar
Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis
Maren N. Stillger, Chia-Yi Chen, Z. W. Lai, Mujia Li +5 more
2022bioRxiv13 citations Open access
Semantic Scholar
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Nicolas W. Wieder, Juliana Coraor Fried, Choah Kim, Eriene-Heidi Sidhom +34 more
2023bioRxiv12 citations Open access
Semantic Scholar
Fitm2 is required for ER homeostasis and normal function of murine liver
L. Bond, Ayon Ibrahim, Z. W. Lai, R. Walzem +4 more
2023Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets
Michelle S. Giedt, Jonathon M. Thomalla, Roger P. White, Matthew R. Johnson +3 more
2023Development11 citations Open access
Semantic Scholar
Membrane proteomics: the development of diagnostics based on protein shedding.
Z. W. Lai, D. Steer, A. Smith
2009Current opinion in molecular therapeutics (Print)11 citations
Semantic Scholar
Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets
Michelle S. Giedt, Jonathon M. Thomalla, Matthew R. Johnson, Z. W. Lai +2 more
2021bioRxiv10 citations Open access
Semantic Scholar
Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses
Z. W. Lai, L. Bolm, H. Fuellgraf, M. Biniossek +10 more
2016BMC Cancer10 citations Open access
Semantic Scholar
Identification of Protease Cleavage Sites by Charge-Based Enrichment of Protein N-Termini.
Z. W. Lai, O. Schilling
2017Methods in molecular biology3 citations
Semantic Scholar
Limited and Degradative Proteolysis in the Context of Posttranslational Regulatory Networks: Current Technical and Conceptional Advances
S. Tholen, M. Koczorowska, Z. W. Lai, Joern Dengjel +1 more
20133 citations
Semantic Scholar
Lipid droplet assembly factor-1 and seipin form a lipid droplet assembly complex
Jeeyun Chung, Xudong Wu, Talley J. Lambert, Z. W. Lai +3 more
20201 citations
Semantic Scholar
The Prognostic Impact of the Carcinoembryonic Antigen in Ampullary Cancer - A Retrospective Single Center Study
H. Fuellgraf, O. Schilling, Z. W. Lai, B. Kulemann +8 more
2017Journal of Cancer1 citations Open access
Semantic Scholar
Quenched fluorescent peptide substrates : Tools for the discovery of novel biomarkers
Z. W. Lai, Iresha Hanchapola, A. Smith
20081 citations
Semantic Scholar
Fitm2 is required for ER homeostasis and normal function of murine liver
L. Bond, Ayon Ibrahim, Z. W. Lai, Rosemary L. Walzem +4 more
2022bioRxiv0 citations Open access
Semantic Scholar
Lipid droplets regulate actin remodeling via prostaglandin signaling during Drosophila 1 oogenesis 2 3
Michelle S. Giedt, Jonathon M. Thomalla, Matthew R. Johnson, Z. W. Lai +1 more
20210 citations
Semantic Scholar
Global Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity
Zhihuan Li, Z. W. Lai, Romain Christiano, Felipe Gazos-Lopes +3 more
20180 citations
Semantic Scholar
System-Wide Profiling of Protein Amino Termini from Formalin-Fixed, Paraffin-Embedded Tissue Specimens for the Identification of Novel Substrates.
Z. W. Lai, O. Schilling
2017Methods in molecular biology0 citations
Semantic Scholar
Quantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines
J. Weißer, Z. W. Lai, P. Bronsert, M. Kuehs +9 more
2015BMC Genomics0 citations Open access
Semantic Scholar

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