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L. Agnelli · SciRah

Researcher profile · Semantic Scholar

L. Agnelli

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L. Agnelli — researcher profile on SciRah

h-index: 49
Works: 197
Citations: 5,884

Most-cited papers

RESCUE OF HIPPO CO-ACTIVATOR YAP1 TRIGGERS DNA DAMAGE-INDUCED APOPTOSIS IN HEMATOLOGICAL CANCERS
F. Cottini, T. Hideshima, Chun-Xiao Xu, M. Sattler +17 more
2014Nature Medicine290 citations Open access
Semantic Scholar
Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity
N. Amodio, Maria Angelica Stamato, G. Juli, E. Morelli +14 more
2018Leukemia239 citations Open access
Semantic Scholar
Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
F. Morabito, L. Mosca, G. Cutrona, L. Agnelli +26 more
2013Clinical Cancer Research174 citations
Semantic Scholar
Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.
M. Bolzoni, M. Chiu, F. Accardi, R. Vescovini +21 more
2016Blood165 citations Open access
Semantic Scholar
Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts.
Irene Scarfò, E. Pellegrino, Elisabetta Mereu, I. Kwee +21 more
2016Blood106 citations
Semantic Scholar
Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction
P. Storti, M. Bolzoni, G. Donofrio, I. Airoldi +16 more
2013Leukemia104 citations
Semantic Scholar
Revealing the impact of structural variants in multiple myeloma
E. Rustad, V. Yellapantula, D. Głodzik, K. Maclachlan +23 more
2020Blood Cancer Discovery97 citations Open access
Semantic Scholar
Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma
E. Taiana, V. Favasuli, D. Ronchetti, K. Todoerti +17 more
2019Leukemia96 citations Open access
Semantic Scholar
Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
M. Lionetti, P. Musto, M. D. Di Martino, S. Fabris +22 more
2013Clinical Cancer Research96 citations Open access
Semantic Scholar
Lenalidomide and low-dose dexamethasone for newly diagnosed primary plasma cell leukemia
P. Musto, V. Simeon, M. Martorelli, Maria Teresa Petrucci +26 more
2014Leukemia94 citations Open access
Semantic Scholar
Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia
D. Ronchetti, L. Mosca, G. Cutrona, Giacomo Tuana +15 more
2013BMC Medical Genomics94 citations Open access
Semantic Scholar
Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma
D. Ronchetti, L. Agnelli, E. Taiana, S. Galletti +5 more
2016OncoTarget91 citations Open access
Semantic Scholar
miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma
E. Minna, Paola Romeo, M. Dugo, L. De Cecco +8 more
2016OncoTarget84 citations Open access
Semantic Scholar
Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules.
M. Bolzoni, P. Storti, S. Bonomini, K. Todoerti +6 more
2013Experimental Hematology79 citations Open access
Semantic Scholar
Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation
M. Lionetti, Marzia Barbieri, K. Todoerti, L. Agnelli +12 more
2015OncoTarget77 citations Open access
Semantic Scholar
Genome‐wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles
L. Mosca, P. Musto, K. Todoerti, Marzia Barbieri +22 more
2013American journal of hematology/oncology73 citations Open access
Semantic Scholar
Long Non-Coding RNAs in Multiple Myeloma
Lucia Nobili, D. Ronchetti, L. Agnelli, E. Taiana +2 more
2018Genes58 citations Open access
Semantic Scholar
lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome
D. Ronchetti, M. Manzoni, L. Agnelli, C. Vinci +18 more
2016Blood Cancer Journal56 citations Open access
Semantic Scholar
High‐throughput sequencing for the identification of NOTCH1 mutations in early stage chronic lymphocytic leukaemia: biological and clinical implications
M. Lionetti, S. Fabris, G. Cutrona, L. Agnelli +18 more
2014British Journal of Haematology56 citations Open access
Semantic Scholar
microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters
M. Negrini, G. Cutrona, Cristian Bassi, S. Fabris +20 more
2014Clinical Cancer Research56 citations Open access
Semantic Scholar
Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
K. Todoerti, L. Agnelli, S. Fabris, M. Lionetti +20 more
2013Clinical Cancer Research55 citations Open access
Semantic Scholar
Improved risk stratification in myeloma using a microRNA‐based classifier
Ping Wu, L. Agnelli, B. Walker, K. Todoerti +10 more
2013British Journal of Haematology55 citations
Semantic Scholar
Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells
M. Bolzoni, G. Donofrio, P. Storti, D. Guasco +13 more
2013Leukemia53 citations Open access
Semantic Scholar
Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma
M. D. Di Martino, P. Guzzi, D. Caracciolo, L. Agnelli +6 more
2015OncoTarget50 citations Open access
Semantic Scholar
Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia
M. Hoxha, S. Fabris, L. Agnelli, V. Bollati +9 more
2014Genes, Chromosomes and Cancer50 citations
Semantic Scholar
A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias
M. Lionetti, Marzia Barbieri, K. Todoerti, L. Agnelli +9 more
2015OncoTarget48 citations Open access
Semantic Scholar
A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma
D. Ronchetti, L. Agnelli, A. Pietrelli, K. Todoerti +3 more
2018Scientific Reports44 citations Open access
Semantic Scholar
Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients
Enrica Calura, A. Bisognin, M. Manzoni, K. Todoerti +10 more
2015OncoTarget43 citations Open access
Semantic Scholar
IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts
M. Bolzoni, D. Ronchetti, P. Storti, G. Donofrio +17 more
2017Haematologica40 citations Open access
Semantic Scholar
Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo
P. Storti, V. Marchica, I. Airoldi, G. Donofrio +18 more
2016Leukemia37 citations
Semantic Scholar
B‐cell receptor configuration and adverse cytogenetics are associated with autoimmune hemolytic anemia in chronic lymphocytic leukemia
Francesco Maura, C. Visco, Erika Falisi, G. Reda +18 more
2012American journal of hematology/oncology34 citations Open access
Semantic Scholar
Long non-coding RNA NEAT1 shows high expression unrelated to molecular features and clinical outcome in multiple myeloma
E. Taiana, D. Ronchetti, V. Favasuli, K. Todoerti +5 more
2018Haematologica33 citations Open access
Semantic Scholar
Chromosome 2p gain in monoclonal B‐cell lymphocytosis and in early stage chronic lymphocytic leukemia
S. Fabris, L. Mosca, G. Cutrona, M. Lionetti +28 more
2013American journal of hematology/oncology28 citations Open access
Semantic Scholar
Molecular profiling of multiple myeloma: from gene expression analysis to next-generation sequencing
L. Agnelli, P. Tassone, A. Neri
2013Expert Opinion on Biological Therapy28 citations
Semantic Scholar
Molecular Tumor Board as a Clinical Tool for Converting Molecular Data Into Real-World Patient Care
A. Vingiani, L. Agnelli, M. Duca, D. Lorenzini +29 more
2023JCO Precision Oncology26 citations Open access
Semantic Scholar
Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia
Francesco Maura, G. Cutrona, L. Mosca, S. Matis +21 more
2015Leukemia and Lymphoma25 citations
Semantic Scholar
Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine
V. Simeon, K. Todoerti, F. La Rocca, A. Caivano +7 more
2015International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
PEOPLE (NTC03447678), a phase II trial to test pembrolizumab as first-line treatment in patients with advanced NSCLC with PD-L1 <50%: a multiomics analysis
Giuseppe Lo Russo, A. Prelaj, J. Dolezal, T. Beninato +32 more
2023Journal for ImmunoTherapy of Cancer22 citations Open access
Semantic Scholar
In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma
D. Ronchetti, M. Manzoni, K. Todoerti, A. Neri +1 more
2016Genes20 citations Open access
Semantic Scholar
Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach
M. Colombo, D. Bagnara, D. Reverberi, S. Matis +14 more
2020Molecular Medicine19 citations Open access
Semantic Scholar
ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC)
Lorenzo Ferrando, A. Vingiani, A. Garuti, C. Vernieri +15 more
2023PLoS Genetics16 citations Open access
Semantic Scholar
Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma
F. Maura, L. Agnelli, D. Leongamornlert, N. Bolli +20 more
2019American journal of hematology/oncology16 citations Open access
Semantic Scholar
Insulin Growth Factor 1 Receptor Expression Is Associated with NOTCH1 Mutation, Trisomy 12 and Aggressive Clinical Course in Chronic Lymphocytic Leukaemia
Francesco Maura, L. Mosca, S. Fabris, G. Cutrona +19 more
2015PLoS ONE15 citations Open access
Semantic Scholar
NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome
D. Ronchetti, V. Favasuli, P. Monti, G. Cutrona +15 more
2020Non-Coding RNA14 citations Open access
Semantic Scholar
Targeted resequencing of FECH locus reveals that a novel deep intronic pathogenic variant and eQTLs may cause erythropoietic protoporphyria (EPP) through a methylation-dependent mechanism
M. Chiara, Ilaria Primon, L. Tarantini, L. Agnelli +4 more
2019Genetics in Medicine13 citations Open access
Semantic Scholar
Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia
D. Ronchetti, Giacomo Tuana, A. Rinaldi, L. Agnelli +12 more
2014Genes, Chromosomes and Cancer13 citations
Semantic Scholar
Expression Pattern and Biological Significance of the lncRNA ST3GAL6-AS1 in Multiple Myeloma
D. Ronchetti, K. Todoerti, C. Vinci, V. Favasuli +10 more
2020Cancers12 citations Open access
Semantic Scholar
The transcriptomic profile of CD138+ cells from patients with early progression from smoldering to active multiple myeloma remains substantially unchanged
P. Storti, L. Agnelli, Benedetta Dalla Palma, K. Todoerti +11 more
2019Haematologica12 citations Open access
Semantic Scholar
The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs.
D. Soncini, S. Orecchioni, Samantha Ruberti, P. Minetto +21 more
2019Haematologica11 citations Open access
Semantic Scholar
Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing
L. Agnelli, A. Bisognin, K. Todoerti, M. Manzoni +6 more
2019Blood Cancer Journal11 citations Open access
Semantic Scholar

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