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S. Pugh · SciRah

Researcher profile · Semantic Scholar

S. Pugh

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S. Pugh — researcher profile on SciRah

h-index: 14
Works: 47
Citations: 1,159

Most-cited papers

Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial.
J. Primrose, S. Falk, M. Finch-Jones, J. Valle +17 more
2014The Lancet Oncology422 citations Open access
Semantic Scholar
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trial
J. Bridgewater, S. Pugh, T. Maishman, Z. Eminton +18 more
2020The Lancet Oncology216 citations Open access
Semantic Scholar
The diagnostic accuracy of a single CEA blood test in detecting colorectal cancer recurrence: Results from the FACS trial
Bethany Shinkins, B. Nicholson, J. Primrose, R. Perera +3 more
2017PLoS ONE75 citations Open access
Semantic Scholar
Site and Stage of Colorectal Cancer Influence the Likelihood and Distribution of Disease Recurrence and Postrecurrence Survival: Data From the FACS Randomized Controlled Trial
S. Pugh, B. Shinkins, A. Fuller, J. Mellor +2 more
2016Annals of Surgery70 citations
Semantic Scholar
A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent.
D. Mant, A. Gray, S. Pugh, H. Campbell +9 more
2017Health Technology Assessment56 citations Open access
Semantic Scholar
Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: a post-hoc analysis of the New EPOC trial
S. Pugh, Raphaële Thiébaut, J. Bridgewater, M. Grisoni +7 more
2017OncoTarget53 citations Open access
Semantic Scholar
Circulating tumour DNA as a biomarker in resectable and irresectable stage IV colorectal cancer; a systematic review and meta-analysis.
Robert P. Jones, S. Pugh, J. Graham, J. Primrose +1 more
2021European Journal of Cancer52 citations Open access
Semantic Scholar
What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up? A systematic review and secondary analysis of a randomised controlled trial.
B. Shinkins, B. Nicholson, T. James, I. Pathiraja +4 more
2017Health Technology Assessment32 citations Open access
Semantic Scholar
Integrated Clinical-Molecular Classification of Colorectal Liver Metastases: A Biomarker Analysis of the Phase 3 New EPOC Randomized Clinical Trial.
R. Katipally, C. Martinez, S. Pugh, J. Bridgewater +7 more
2023JAMA Oncology28 citations Open access
Semantic Scholar
Long non-coding RNAs within the tumour microenvironment and their role in tumour-stroma cross-talk.
Filippo Del Vecchio, Gui H. Lee, Joamir Hawezi, R. Bhome +9 more
2018Cancer Letters25 citations Open access
Semantic Scholar
T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases
S. Pugh, R. Harrison, J. Primrose, S. Khakoo
2014BMC Cancer25 citations Open access
Semantic Scholar
Population-based observational study of acute pancreatitis in southern England.
A. Mirnezami, B. Knight, Brendan Moran, F. Noble +9 more
2019Annals of the Royal College of Surgeons of England22 citations Open access
Semantic Scholar
Laparoscopic versus open resections in the posterosuperior liver segments within an enhanced recovery programme (ORANGE Segments): study protocol for a multicentre randomised controlled trial
C. Kuemmerli, R. Fichtinger, A. Moekotte, L. Aldrighetti +21 more
2022Trials15 citations Open access
Semantic Scholar
Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study
S. Pugh, M. Bowers, A. Ball, S. Falk +19 more
2016British Journal of Cancer15 citations Open access
Semantic Scholar
Perioperative chemotherapy with or without cetuximab in patients (pts) with resectable colorectal liver metastasis (CRLM): Mature analysis of overall survival (OS) in the New EPOC randomised controlled trial
J. Bridgewater, S. Pugh, Amy Whitehead, L. Stanton +15 more
20177 citations Open access
Semantic Scholar
Cetuximab Is Contraindicated in the Perioperative Treatment of Colorectal Liver Metastases.
J. Primrose, D. Cunningham, O. Garden, T. Maughan +10 more
2015Journal of Clinical Oncology7 citations Open access
Semantic Scholar
A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy
L. Spurr, C. Martinez, R. Katipally, Soumya C. Iyer +11 more
2022npj Precision Oncology6 citations Open access
Semantic Scholar
Scheduled use of CEA and CT follow-up to detect recurrence of colorectal cancer: 6-12 year results from the FACS randomised controlled trial
S. Pugh, D. Mant, B. Shinkins, J. Mellor +2 more
20166 citations Open access
Semantic Scholar
Development and validation of a model to predict outcomes of colon cancer surveillance
J. Rose, Laura Homa, C. Kong, G. Cooper +8 more
2019Cancer Causes and Control4 citations
Semantic Scholar
EGFR ligand expression levels and detriment from cetuximab in patients with operable liver metastases from colorectal cancer
S. Pugh, J. Bridgewater, J. Primrose
20164 citations Open access
Semantic Scholar
Mir-31-3p as a predictive biomarker of cetuximab effects in a post hoc analysis of new EPOC phase III trial.
P. Laurent-Puig, J. Bridgewater, J. Primrose, S. Pugh +11 more
20144 citations
Semantic Scholar
OC-055 What is the true incidence of metachronous colorectal liver metastases? evidence from the UK FACS (follow-up after colorectal surgery) trial (ISRCTN: 41458548)
S. Pugh, A. Fuller, P. Rose, R. Perera-Salazar +4 more
2012Gut3 citations Open access
Semantic Scholar
543PMIR-31-3P IS A PREDICTIVE BIOMARKER OF CETUXIMAB EFFECTS IN A POST-HOC ANALYSIS IN THE NEW EPOC STUDY.
P. Laurent-Puig, John A. Bridgewater, J. Primrose, S. Pugh +12 more
2014Annals of Oncology2 citations Open access
Semantic Scholar
The follow-up after colorectal cancer surgery trial: randomised trial of follow-up after colorectal cancer surgery and outcome following recurrence
S. Pugh, A. Fuller, R. Perera, S. George +2 more
20142 citations
Semantic Scholar
Analysis of progression-free survival in the new EPOC study in an "all wild-type" population.
J. Bridgewater, S. Pugh, K. Moutasim, G. Thomas +15 more
20142 citations
Semantic Scholar
Analysis of primary and acquired resistance to cetuximab from multiomic data in the New EPOC trial.
S. Pugh, E. Domingo, S. Richman, P. Dunne +7 more
2023Journal of Clinical Oncology1 citations Open access
Semantic Scholar
Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study.
J. Primrose, S. Pugh, G. Thomas, M. Ellis +2 more
2021Health Technology Assessment1 citations Open access
Semantic Scholar
Hepatic metastases resection after cetuximab: are we missing something? - Authors' reply.
S. Pugh, J. Bridgewater, J. Primrose
2020The Lancet Oncology1 citations
Semantic Scholar
Association between density of tumor infiltrating lymphocytes and disease-free survival (DFS) in patients with resected stage I-III colorectal cancer in the FACS randomized trial.
S. Pugh, K. Moutasim, N. Jenkins, B. Shinkins +3 more
20181 citations
Semantic Scholar
T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases
S. Pugh, R. Harrison, J. Primrose, S. Khakoo
2014BMC Cancer1 citations Open access
Semantic Scholar
The National Library of Wales on Flickr Commons
S. Pugh
20111 citations
Semantic Scholar
The impact of COVID-19 on clinical cancer care: An individual-patient level analysis.
Lynsey M. Drewett, S. Pugh, R. Kieran, B. Nair +16 more
20210 citations
Semantic Scholar
Chromosomal instability mediates immune exclusion and response to cytotoxic chemotherapy in colorectal liver metastases
C. Martinez, L. Spurr, Soumya C. Iyer, S. Pugh +10 more
2021bioRxiv0 citations Open access
Semantic Scholar
Surgical quality and the impact of liver resection on outcome in the new EPOC study
S. Pugh, J. Bridgewater, M. Finch-Jones, M. Rees +14 more
20170 citations
Semantic Scholar
Main study: methods
B. Shinkins, B. Nicholson, T. James, I. Pathiraja +4 more
20170 citations
Semantic Scholar
Main study: results
B. Shinkins, B. Nicholson, T. James, I. Pathiraja +4 more
20170 citations
Semantic Scholar
Main study: aim and objectives
B. Shinkins, B. Nicholson, T. James, I. Pathiraja +4 more
20170 citations
Semantic Scholar
Abstract 1488: Altered skeletal muscle mitochondrial function and redox biology with chemotherapy and exercise in a colorectal cancer mouse model
M. West, A. Roman, R. Astin, S. Pugh +11 more
20170 citations
Semantic Scholar
Prognostic utility of the presence of extramural vascular invasion in stage II and III colorectal cancer: Data from the FACS randomised controlled trial.
S. Pugh, D. Mant, N. Jenkins, A. Mirnezami +4 more
20160 citations
Semantic Scholar
Chapter-15 A Review of Recent Randomised Controlled Trials in Surgery
S. Pugh, N. Jenkins
20150 citations
Semantic Scholar
Association between c-Met expression, miR-31-3p expression and progression free survival in the New EPOC study
S. Pugh, J. Bridgewater, K. Moutasim, G. Thomas +16 more
20150 citations
Semantic Scholar
Use of FLIM histology-based HER2-HER3 heterodimer quantification and a Bayesian latent class proportional hazards model to predict cetuximab response in the COIN and new EPOC trials.
T. Ng, G. Weitsman, P. Barber, K. Lawler +12 more
20150 citations
Semantic Scholar
PTH-280 Follow up after colorectal cancer: time to revise the guidance?
K. Pearson, S. Pugh, G. Branagan, J. Primrose
20150 citations
Semantic Scholar
Patterns of progression, treatment of progressive disease, and postprogression survival in the new EPOC study.
S. Pugh, A. Ball, M. Bowers, S. Falk +16 more
20140 citations Open access
Semantic Scholar
542PANALYSIS OF PROGRESSION FREE SURVIVAL IN THE NEW EPOC STUDY IN AN ALL RAS WILD-TYPE POPULATION.
John A. Bridgewater, S. Pugh, K. Moutasim, G. Thomas +16 more
2014Annals of Oncology0 citations Open access
Semantic Scholar
Experience of delivering intra-operative radiotherapy in a DGH
S. Pugh, A. Shetty, V. Hall, S. Raj +2 more
20130 citations
Semantic Scholar
What is the incidence of resectable recurrence after surgery for primary colorectal cancer? Evidence from the UK FACS (Follow-up After Colorectal Surgery) trial
S. Pugh, A. Fuller, R. Perera-Salazar, D. Mant +1 more
20120 citations
Semantic Scholar

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