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J. Ingle · SciRah

Researcher profile · Semantic Scholar

J. Ingle

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J. Ingle — researcher profile on SciRah

h-index: 89
Works: 434
Citations: 57K

Most-cited papers

Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials
B. Asselain, W. Barlow, J. Bartlett, J. Bergh +106 more
2018The Lancet Oncology930 citations Open access
Semantic Scholar
Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer
P. Francis, O. Pagani, G. Fleming, B. Walley +32 more
2018New England Journal of Medicine582 citations Open access
Semantic Scholar
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials
R. Gray, Rosie Bradley, J. Braybrooke, Zu-Lian Liu +162 more
2019The Lancet328 citations Open access
Semantic Scholar
A comprehensive analysis of breast cancer microbiota and host gene expression
Kevin J. Thompson, J. Ingle, Xiao-Jia Tang, N. Chia +14 more
2017PLoS ONE165 citations Open access
Semantic Scholar
Impact of Histopathology, Tumor-Infiltrating Lymphocytes and Adjuvant Chemotherapy on Prognosis of Triple-Negative Breast Cancer
R. Leon-Ferre, M. Polley, Heshan Liu, J. Gilbert +14 more
2017Breast Cancer Research and Treatment104 citations Open access
Semantic Scholar
Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.
K. Visvanathan, MaryJo S Fackler, Zhe Zhang, Z. Lopez-Bujanda +14 more
2017Journal of Clinical Oncology102 citations Open access
Semantic Scholar
BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study
P. Fasching, S. Loibl, Chun-Ling Hu, S. Hart +23 more
2018Journal of Clinical Oncology100 citations Open access
Semantic Scholar
Metaplastic breast cancer has a poor response to neoadjuvant systemic therapy
Z. Al-Hilli, G. Choong, M. Keeney, D. Visscher +3 more
2019Breast Cancer Research and Treatment85 citations Open access
Semantic Scholar
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
A. Leontovich, M. Jalalirad, J. Salisbury, L. Mills +19 more
2018Breast Cancer Research78 citations Open access
Semantic Scholar
Phase III randomized trial of bisphosphonates as adjuvant therapy in breast cancer: S0307.
J. Gralow, W. Barlow, A. Paterson, Jie-Ling Miao +19 more
2019Journal of the National Cancer Institute72 citations Open access
Semantic Scholar
First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer.
M. Goetz, V. Suman, J. Reid, D. Northfelt +22 more
2017Journal of Clinical Oncology71 citations Open access
Semantic Scholar
Association Between 21-Gene Assay Recurrence Score and Locoregional Recurrence Rates in Patients With Node-Positive Breast Cancer.
W. Woodward, W. Barlow, R. Jagsi, T. Buchholz +14 more
2020JAMA Oncology68 citations Open access
Semantic Scholar
Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients
N. Norton, Bahaaeldin Youssef, D. Hillman, A. Nassar +17 more
2020npj Breast Cancer63 citations Open access
Semantic Scholar
Evaluation of Alisertib Alone or Combined With Fulvestrant in Patients With Endocrine-Resistant Advanced Breast Cancer
Tufia C. Haddad, V. Suman, Antonino B. D’Assoro, Jodi M. Carter +19 more
2023JAMA Oncology61 citations Open access
Semantic Scholar
Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance
M. Jalalirad, Tufia C. Haddad, J. Salisbury, D. Radisky +17 more
2021Oncogene60 citations Open access
Semantic Scholar
Adjuvant Endocrine Therapy in Premenopausal Breast Cancer: 12-Year Results From SOFT
P. Francis, G. Fleming, I. Láng, E. Ciruelos +23 more
2022Journal of Clinical Oncology59 citations Open access
Semantic Scholar
Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study
Jia Yu, B. Qin, A. Moyer, J. Sinnwell +26 more
2017Breast Cancer Research55 citations Open access
Semantic Scholar
ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis
Jordan M. Reese, Elizabeth S. Bruinsma, A. W. Nelson, I. Chernukhin +9 more
2018Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
Genomic characterisation of hormone receptor-positive breast cancer arising in very young women
S. Luen, G. Viale, S. Nik-Zainal, P. Savas +34 more
2023Annals of Oncology52 citations Open access
Semantic Scholar
Characteristics and Spatially Defined Immune (micro)landscapes of Early-stage PD-L1–positive Triple-negative Breast Cancer
Jodi M. Carter, M. Polley, R. Leon-Ferre, J. Sinnwell +13 more
2021Clinical Cancer Research51 citations Open access
Semantic Scholar
Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer
Jodi M. Carter, S. Chumsri, D. Hinerfeld, Yao-Hua Ma +22 more
2023Nature Communications45 citations Open access
Semantic Scholar
Ketamine and Ketamine Metabolites as Novel Estrogen Receptor Ligands: Induction of Cytochrome P450 and AMPA Glutamate Receptor Gene Expression
Ming-Fen Ho, Cristina Correia, J. Ingle, R. Kaddurah-Daouk +3 more
2018Biochemical Pharmacology45 citations Open access
Semantic Scholar
The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1
J. Cairns, J. Ingle, K. Kalari, L. Shepherd +4 more
2019Breast Cancer Research42 citations Open access
Semantic Scholar
Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response
Kevin J. Thompson, R. Leon-Ferre, J. Sinnwell, D. Zahrieh +16 more
2022NAR Cancer39 citations Open access
Semantic Scholar
ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer
Jordan M. Reese, Elizabeth S. Bruinsma, D. Monroe, V. Negron +4 more
2017OncoTarget39 citations Open access
Semantic Scholar
Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues.
J. Hawse, Jodi M. Carter, K. Aspros, Elizabeth S. Bruinsma +6 more
2019Breast Cancer Research and Treatment38 citations Open access
Semantic Scholar
Risk factors for bisphosphonate-associated osteonecrosis of the jaw in the prospective randomized trial of adjuvant bisphosphonates for early-stage breast cancer (SWOG 0307)
D. Kizub, Jie-Ling Miao, M. Schubert, A. Paterson +7 more
2020Supportive Care in Cancer35 citations Open access
Semantic Scholar
A clinical calculator to predict disease outcomes in women with triple-negative breast cancer
M. Polley, R. Leon-Ferre, S. Leung, A. Cheng +16 more
2021Breast Cancer Research and Treatment33 citations Open access
Semantic Scholar
Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial
H. Richardson, V. Ho, R. Pasquet, Ravinder J. Singh +4 more
2020Menopause32 citations Open access
Semantic Scholar
Phase I trial to evaluate the addition of alisertib to fulvestrant in women with endocrine-resistant, ER+ metastatic breast cancer
Tufia C. Haddad, Antonino B. D’Assoro, V. Suman, M. Opyrchal +4 more
2017Breast Cancer Research and Treatment31 citations Open access
Semantic Scholar
Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor α
J. Ingle, J. Cairns, V. Suman, L. Shepherd +20 more
2020Clinical Cancer Research30 citations Open access
Semantic Scholar
Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action
J. Cairns, J. Ingle, Tanda M. Dudenkov, K. Kalari +13 more
2020JCI Insight30 citations Open access
Semantic Scholar
SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1
J. Cairns, J. Ingle, L. Wickerham, R. Weinshilboum +2 more
2017PLoS Genetics26 citations Open access
Semantic Scholar
SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway
Tanda M. Dudenkov, J. Ingle, A. Buzdar, M. Robson +15 more
2017Breast Cancer Research and Treatment26 citations Open access
Semantic Scholar
Effects of Celecoxib and Low-dose Aspirin on Outcomes in Adjuvant Aromatase Inhibitor–Treated Patients: CCTG MA.27
K. Strasser-Weippl, M. Higgins, J. W. Chapman, J. Ingle +12 more
2018Journal of the National Cancer Institute25 citations Open access
Semantic Scholar
Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells
M. Opyrchal, Małgorzata Gil, J. Salisbury, M. Goetz +10 more
2017OncoTarget24 citations Open access
Semantic Scholar
Pharmacological targeting of androgen receptor elicits context-specific effects in estrogen receptor-positive breast cancer
Lixuan Wei, Huan-Yao Gao, Jia Yu, Huan Zhang +10 more
2022Cancer Research23 citations Open access
Semantic Scholar
A randomized trial (MA.17R) of extending adjuvant letrozole for 5 years after completing an initial 5 years of aromatase inhibitor therapy alone or preceded by tamoxifen in postmenopausal women with early-stage breast cancer.
P. Goss, J. Ingle, K. Pritchard, N. Robert +16 more
201623 citations
Semantic Scholar
Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer
S. Jayaraman, X. Hou, M. Kuffel, V. Suman +18 more
2020Breast Cancer Research22 citations Open access
Semantic Scholar
Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27
P. Niravath, Bing-Shu E. Chen, J. Chapman, S. Agarwal +12 more
2017Clinical Breast Cancer20 citations Open access
Semantic Scholar
Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM.
M. Goetz, V. Suman, Yusuke Nakamura, K. Kiyotani +2 more
2019Journal of Clinical Oncology19 citations Open access
Semantic Scholar
Quality of Life From Canadian Cancer Trials Group MA.17R: A Randomized Trial of Extending Adjuvant Letrozole to 10 Years.
J. Lemieux, M. Brundage, W. Parulekar, P. Goss +9 more
2018Journal of Clinical Oncology19 citations Open access
Semantic Scholar
TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88–Dependent Nuclear Factor-κB Activation: Single-Nucleotide Polymorphism– and Selective Estrogen Receptor Modulator–Dependent Modification of Inflammation and Immune Response
Ming-Fen Ho, J. Ingle, T. Bongartz, K. Kalari +6 more
2017Molecular Pharmacology18 citations Open access
Semantic Scholar
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer
K. Aspros, Jodi M. Carter, T. Hoskin, V. Suman +23 more
2022npj Breast Cancer15 citations Open access
Semantic Scholar
Patient Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY)
J. Boughey, V. Suman, Jia Yu, K. Santo +16 more
2021Clinical Cancer Research15 citations Open access
Semantic Scholar
Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial.
K. Visvanathan, L. Cope, M. Fackler, M. Considine +16 more
2022Clinical Cancer Research14 citations Open access
Semantic Scholar
Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction between SLC38A7 and ALPPL2
Tanda M. Dudenkov, Duan Liu, J. Cairns, Sandhya Devarajan +17 more
2019Clinical pharmacology and therapy14 citations Open access
Semantic Scholar
PANOPLY: Omics-guided drug prioritization method tailored to an individual patient
K. Kalari, J. Sinnwell, Kevin J. Thompson, Xiao-Jia Tang +9 more
2017bioRxiv14 citations Open access
Semantic Scholar
Development and characterization of novel endoxifen-resistant breast cancer cell lines highlight numerous differences from tamoxifen-resistant models
Calley J. Jones, M. Subramaniam, M. Emch, Elizabeth S. Bruinsma +3 more
2021Molecular Cancer Research9 citations Open access
Semantic Scholar
Anastrozole regulates fatty acid synthase in breast cancer
J. Cairns, J. Ingle, K. Kalari, M. Goetz +5 more
2021Molecular Cancer Therapeutics8 citations Open access
Semantic Scholar

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