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P. Mazur · SciRah

Researcher profile · Semantic Scholar

P. Mazur

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P. Mazur — researcher profile on SciRah

h-index: 34
Works: 66
Citations: 5,165

Most-cited papers

EGF Receptor is Required for KRAS-induced Pancreatic Tumorigenesis
Christine M. Ardito, B. Grüner, Kenneth K. Takeuchi, Clara Lubeseder-Martellato +22 more
2012Cancer Cell521 citations Open access
Semantic Scholar
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
P. Mazur, A. Herner, S. Mello, M. Wirth +28 more
2015Nature Medicine374 citations Open access
Semantic Scholar
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
P. Mazur, N. Reynoird, P. Khatri, P. Jansen +13 more
2014Nature362 citations Open access
Semantic Scholar
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
N. Jahchan, J. Dudley, P. Mazur, Natasha M. Flores +13 more
2013Cancer Discovery343 citations Open access
Semantic Scholar
Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice
F. Geisler, F. Nagl, P. Mazur, Marcel Lee +5 more
2008Hepatology225 citations Open access
Semantic Scholar
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
P. Viatour, U. Ehmer, L. Saddic, C. Dorrell +11 more
2011Journal of Experimental Medicine219 citations Open access
Semantic Scholar
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma
P. Mazur, H. Einwächter, Marcel Lee, B. Sipos +8 more
2010Proceedings of the National Academy of Sciences of the United States of America210 citations Open access
Semantic Scholar
Neat1 is a p53-inducible lincRNA essential for transformation suppression
S. Mello, Carolyn S. Sinow, Nitin Raj, P. Mazur +10 more
2017Genes & Development202 citations Open access
Semantic Scholar
IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors
K. Jameson, P. Mazur, A. Zehnder, Jia-Jing Zhang +3 more
2013Nature Medicine198 citations Open access
Semantic Scholar
Evolution of Immune and Stromal Cell States and Ecotypes during Gastric Adenocarcinoma Progression
Rui-Ping Wang, Shumei Song, Jiang-Jiang Qin, Katsuhiro Yoshimura +35 more
2023Cancer Cell179 citations Open access
Semantic Scholar
METTL13 methylation of eEF1A increases translational output to promote tumorigenesis
Shuo Liu, Simone Hausmann, Scott M. Carlson, M. E. Fuentes +21 more
2019Cell171 citations Open access
Semantic Scholar
Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria
T. Jagielski, J. van Ingen, Nalin Rastogi, J. Dziadek +2 more
2014BioMed Research International165 citations Open access
Semantic Scholar
Notch signaling is required for exocrine regeneration after acute pancreatitis.
J. Siveke, Clara Lubeseder-Martellato, Marcel Lee, P. Mazur +3 more
2008Gastroenterology163 citations Open access
Semantic Scholar
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
A. Vallejo, N. Perurena, E. Guruceaga, P. Mazur +19 more
2017Nature Communications150 citations Open access
Semantic Scholar
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma
Ron Chen, P. Khatri, P. Mazur, M. Polin +8 more
2014Cancer Research146 citations Open access
Semantic Scholar
Early requirement of Rac1 in a mouse model of pancreatic cancer.
I. Heid, Clara Lubeseder-Martellato, B. Sipos, P. Mazur +3 more
2011Gastroenterology138 citations Open access
Semantic Scholar
Elevated NSD3 Histone Methylation Activity Drives Squamous Cell Lung Cancer
G. Yuan, Natasha M. Flores, Simone Hausmann, Shane M. Lofgren +18 more
2021Nature136 citations Open access
Semantic Scholar
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues
M. Aichler, C. Seiler, Monica Tost, J. Siveke +11 more
2012Journal of Pathology126 citations
Semantic Scholar
Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology
P. Mazur, J. Siveke
2011Gut117 citations
Semantic Scholar
Conditional ablation of Notch signaling in pancreatic development
H. Nakhai, J. Siveke, Bettina Klein, L. Mendoza-Torres +6 more
2008Development87 citations Open access
Semantic Scholar
NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
Deepanwita Sengupta, Liyong Zeng, Yu-Mei Li, Simone Hausmann +18 more
2021Molecules and Cells83 citations Open access
Semantic Scholar
Identification and targeting of long-term tumor-propagating cells in small cell lung cancer
N. Jahchan, Jing S. Lim, Becky Bola, K. Morris +19 more
2016Cell Reports83 citations Open access
Semantic Scholar
Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors
G. Krampitz, B. George, S. Willingham, J. Volkmer +15 more
2016Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model
A. Baumgart, P. Mazur, M. Anton, Martina Rudelius +9 more
2014Oncogene78 citations
Semantic Scholar
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin +27 more
2022Gut77 citations
Semantic Scholar
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
Zhentian Wang, Simone Hausmann, Ruitu Lyu, Tie-Mei Li +18 more
2020Cancer Cell74 citations Open access
Semantic Scholar
Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
P. Mazur, N. Reynoird, Timo Stellfeld, Natasha M. Flores +10 more
201674 citations
Semantic Scholar
MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer
B. Grüner, Hannes Hahne, P. Mazur, M. Trajkovic-Arsic +10 more
2012PLoS ONE60 citations Open access
Semantic Scholar
Multifaceted role for p53 in pancreatic cancer suppression
S. Mello, B. Flowers, P. Mazur, James J. Lee +8 more
2023Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Identification of Epidermal Pdx1 Expression Discloses Different Roles of Notch1 and Notch2 in Murine KrasG12D-Induced Skin Carcinogenesis In Vivo
P. Mazur, B. Grüner, H. Nakhai, B. Sipos +5 more
2010PLoS ONE48 citations Open access
Semantic Scholar
Immunotherapy in Pancreatic Adenocarcinoma: Beyond “Copy / Paste”
Robert Hester, P. Mazur, F. McAllister
2021Clinical Cancer Research41 citations Open access
Semantic Scholar
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer
Guozhen Gao, Simone Hausmann, Natasha M. Flores, Ana Morales Benitez +9 more
2023Nature Communications38 citations Open access
Semantic Scholar
Expression and Clinicopathological Significance of Notch Signaling and Cell-Fate Genes in Biliary Tract Cancer
P. Mazur, M. Riener, W. Jochum, G. Kristiansen +3 more
2012American Journal of Gastroenterology35 citations
Semantic Scholar
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities
Chang Xu, K. Huang, J. Law, J. Chua +37 more
2023Gut34 citations
Semantic Scholar
SMYD3 impedes small cell lung cancer sensitivity to alkylation damage through RNF113A methylation-phosphorylation crosstalk
Valentina Lukinović, Simone Hausmann, Gaël S. Roth, Clement Oyeniran +16 more
2022Cancer Discovery20 citations Open access
Semantic Scholar
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis
Alexandre G. Casanova, Gaël S. Roth, Simone Hausmann, Xiao-Yin Lu +19 more
2024Cell Discovery17 citations Open access
Semantic Scholar
Current methods in mouse models of pancreatic cancer.
P. Mazur, A. Herner, Florian Neff, J. Siveke
2015Methods in molecular biology11 citations
Semantic Scholar
Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase
P. Mazur, O. Gozani, J. Sage, N. Reynoird
2016Translational Cancer Research10 citations Open access
Semantic Scholar
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis
Alexandre G. Casanova, Gaël S. Roth, Simone Hausmann, Xiao-Yin Lu +15 more
2023bioRxiv9 citations Open access
Semantic Scholar
Antibody toolkit to investigate eEF1A methylation dynamics in mRNA translation elongation
Robert Mealey-Farr, Jinho Jeong, Juhyung Park, Shuo Liu +7 more
2023Journal of Biological Chemistry8 citations Open access
Semantic Scholar
Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides
Xiao-Yin Lu, Shane M. Lofgren, Yuehui Zhao, P. Mazur
2023Nature Biomedical Engineering4 citations
Semantic Scholar
Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
P. Mazur, A. Herner, S. Mello, Matthias Wirth +28 more
2024Nature Medicine3 citations Open access
Semantic Scholar
Abstract 4610: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
N. Jahchan, J. Dudley, P. Mazur, Natasha M. Flores +13 more
20143 citations
Semantic Scholar
Abstract PR11: Egfr is essential for Ras-driven pancreatic cancer development
B. Grüner, Clara Lubeseder-Martellato, T. Briel, P. Mazur +2 more
20112 citations
Semantic Scholar
Abstract B054: Histone lysine methyltransferase NSD3 governs transcriptional programs that drive pancreatic neuroendocrine tumors
M. E. Fuentes, Simone Hausmann, Natasha M. Flores, Xiao-Yin Lu +1 more
2022Cancer Research1 citations
Semantic Scholar
Abstract IA02: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer.
N. Jahchan, D. Joel, P. Mazur, J. Neal +3 more
20141 citations
Semantic Scholar
Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
P. Mazur, A. Herner, S. Mello, Matthias Wirth +28 more
2026Nature Medicine0 citations Open access
Semantic Scholar
Abstract 1194: Evolution of immune and stromal cell states during the gastric cancer continuum
Rui-Ping Wang, Shumei Song, Jiang-Jiang Qin, Katsuhiro Yoshimura +21 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 1305: Cellular and molecular landscape of metastatic gastric cancer
En-Yu Dai, Jiang-Jiang Qin, Jibo Wu, Natasha M. Flores +26 more
2023Cancer Research0 citations
Semantic Scholar
Abstract A080: METTL21A inhibits pancreatic ductal adenocarcinoma tumorigenesis through methylation of HSPA1/8
Xiao-Jie Yang, Mohamad Zoabi, Simone Hausmann, Natasha M. Flores +5 more
2022Cancer Research0 citations
Semantic Scholar

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