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U. Ehmer · SciRah

Researcher profile · Semantic Scholar

U. Ehmer

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U. Ehmer — researcher profile on SciRah

h-index: 28
Works: 84
Citations: 2,641

Most-cited papers

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
P. Viatour, U. Ehmer, L. Saddic, C. Dorrell +11 more
2011Journal of Experimental Medicine219 citations Open access
Semantic Scholar
Human hepatic organoids for the analysis of human genetic diseases.
Y. Guan, Dan-Ling Xu, Phillip M. Garfin, U. Ehmer +8 more
2017JCI Insight215 citations Open access
Semantic Scholar
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice
Julia Weber, R. Öllinger, Mathias J. Friedrich, U. Ehmer +28 more
2015Proceedings of the National Academy of Sciences of the United States of America186 citations Open access
Semantic Scholar
Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP‐glucuronosyltransferase UGT1A4
U. Ehmer, A. Vogel, J. Schütte, Britta Krone +2 more
2004Hepatology169 citations Open access
Semantic Scholar
Control of proliferation and cancer growth by the Hippo signaling pathway
U. Ehmer, J. Sage
2015Molecular Cancer Research149 citations Open access
Semantic Scholar
Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.
A. Vogel, S. Kneip, A. Barut, U. Ehmer +3 more
2001Gastroenterology142 citations Open access
Semantic Scholar
Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach.
S. Kalthoff, U. Ehmer, N. Freiberg, M. Manns +1 more
2010Gastroenterology127 citations
Semantic Scholar
Interaction between Oxidative Stress Sensor Nrf2 and Xenobiotic-activated Aryl Hydrocarbon Receptor in the Regulation of the Human Phase II Detoxifying UDP-glucuronosyltransferase 1A10*
S. Kalthoff, U. Ehmer, N. Freiberg, M. Manns +1 more
2010Journal of Biological Chemistry124 citations Open access
Semantic Scholar
Promotion of growth factor signaling as a critical function of β-catenin during HCC progression
Eunsun Kim, Amanda Lisby, Connie Ma, N. Lo +4 more
2019Nature Communications99 citations Open access
Semantic Scholar
Age independent survival benefit for patients with hepatocellular carcinoma (HCC) without metastases at diagnosis: a population-based study
E. de Toni, A. Schlesinger-raab, M. Fuchs, W. Schepp +9 more
2019Gut97 citations Open access
Semantic Scholar
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer
R. Rad, Lena Rad, Wei Wang, Alexander J. Strong +41 more
2014Nature Genetics83 citations
Semantic Scholar
Regulation of localization and function of the transcriptional co-activator YAP by angiomotin
S. Moleirinho, Sany Hoxha, Vinay Mandati, G. Curtale +3 more
2017eLife77 citations Open access
Semantic Scholar
Hippo Signaling in the Liver – A Long and Ever-Expanding Story
S. Manmadhan, U. Ehmer
2019Front. Cell Dev. Biol.76 citations Open access
Semantic Scholar
Variability and Function of Family 1 Uridine-5′-Diphosphate Glucuronosyltransferases (UGT1A)
C. Strassburg, S. Kalthoff, U. Ehmer
2008Critical reviews in clinical laboratory sciences66 citations
Semantic Scholar
Genetic variability of aryl hydrocarbon receptor (AhR)-mediated regulation of the human UDP glucuronosyltransferase (UGT) 1A4 gene.
T. Erichsen, U. Ehmer, S. Kalthoff, T. Lankisch +4 more
2008Toxicology and Applied Pharmacology63 citations
Semantic Scholar
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression
Amy Tarangelo, N. Lo, R. Teng, Eunsun Kim +6 more
2015Nature Communications62 citations Open access
Semantic Scholar
Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.
T. Erichsen, A. Aehlen, U. Ehmer, S. Kalthoff +2 more
2010Journal of Hepatology52 citations
Semantic Scholar
Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation
U. Ehmer, S. Kalthoff, B. Fakundiny, B. Pabst +4 more
2012Hepatology51 citations Open access
Semantic Scholar
Family 1 uridine-5′-diphosphate glucuronosyltransferases (UGT1A): from Gilbert’s syndrome to genetic organization and variability
C. Strassburg, T. Lankisch, M. Manns, U. Ehmer
2008Archives of Toxicology51 citations
Semantic Scholar
Polymorphisms of the Carcinogen Detoxifying UDP-Glucuronosyltransferase UGT1A7 in Proximal Digestive Tract Cancer
A. Vogel, J. Ockenga, U. Ehmer, A. Barut +4 more
2002Zeitschrift für Gastroenterologie - German Journal of Gastroenterology51 citations
Semantic Scholar
Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): a phase 3 randomised controlled trial.
P. Merle, J. Blanc, J. Phelip, G. Pelletier +89 more
2019The Lancet Gastroenterology and Hepatology46 citations Open access
Semantic Scholar
Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.
T. Lankisch, G. Behrens, U. Ehmer, Ulrike Möbius +7 more
2009Journal of Hepatology44 citations
Semantic Scholar
Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene
T. Lankisch, T. C. Gillman, T. Erichsen, U. Ehmer +5 more
2008Archives of Toxicology42 citations
Semantic Scholar
Real-World Data for Lenvatinib in Hepatocellular Carcinoma (ELEVATOR): A Retrospective Multicenter Study
S. Welland, C. Leyh, F. Finkelmeier, A. Jefremow +25 more
2022Liver Cancer39 citations Open access
Semantic Scholar
Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo
U. Ehmer, Anne-Flore Zmoos, Raymond K. Auerbach, Dedeepya Vaka +3 more
2014Cell Reports39 citations Open access
Semantic Scholar
Community-driven development of a modified progression-free survival ratio for precision oncology
A. Mock, C. Heilig, S. Kreutzfeldt, D. Huebschmann +101 more
2019ESMO Open36 citations Open access
Semantic Scholar
Atezolizumab and bevacizumab with transarterial chemoembolization in hepatocellular carcinoma: the DEMAND trial protocol.
N. Ben Khaled, M. Seidensticker, J. Ricke, J. Mayerle +18 more
2022Future Oncology33 citations
Semantic Scholar
Rapid allelic discrimination by TaqMan PCR for the detection of the Gilbert's syndrome marker UGT1A1*28.
U. Ehmer, T. Lankisch, T. Erichsen, S. Kalthoff +4 more
2008Journal of Molecular Diagnostics32 citations Open access
Semantic Scholar
Progression after Immunotherapy for Fibrolamellar Carcinoma
U. Bauer, Carolin Mogler, R. Braren, H. Algül +2 more
2019Visceral Medicine25 citations Open access
Semantic Scholar
Usefulness of 1,3 Beta-d-Glucan Detection in non-HIV Immunocompromised Mechanical Ventilated Critically Ill Patients with ARDS and Suspected Pneumocystis jirovecii Pneumonia
T. Lahmer, C. D. da Costa, J. Held, Sebastian Rasch +3 more
2017Mycopathologia25 citations
Semantic Scholar
RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo
Ryan J. Bourgo, U. Ehmer, J. Sage, E. Knudsen
2011Molecular Biology of the Cell15 citations Open access
Semantic Scholar
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
Thorsten Kaltenbacher, Jessica Löprich, Roman Maresch, Julia Weber +22 more
2022Nature Protocols14 citations
Semantic Scholar
Shared Regulation of UGT1A7 by Hepatocyte Nuclear Factor (HNF) 1α and HNF4α
U. Ehmer, S. Kalthoff, T. Lankisch, N. Freiberg +2 more
2010Drug Metabolism And Disposition13 citations
Semantic Scholar
Pseudallescheria boydii with Aspergillus fumigatus and Aspergillus terreus in a Critically Ill Hematopoietic Stem Cell Recipient with ARDS
T. Lahmer, M. Messer, U. Ehmer, S. Eser +4 more
2015Mycopathologia11 citations Open access
Semantic Scholar
High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy
U. Bauer, S. Gerum, F. Roeder, S. Münch +16 more
2021World Journal of Gastroenterology10 citations Open access
Semantic Scholar
Constitutive and Inducible Systems for Genetic In Vivo Modification of Mouse Hepatocytes Using Hydrodynamic Tail Vein Injection.
Eric K. Hubner, C. Lechler, T. Rösner, B. Kohnke-Ertel +2 more
2018Journal of Visualized Experiments10 citations Open access
Semantic Scholar
Sorafenib Versus Lenvatinib-Based Sequential Systemic Therapy for Advanced Hepatocellular Carcinoma: A Real-World Analysis
C. Leyh, U. Ehmer, D. Roessler, Alexander B. Philipp +9 more
2022Cancers9 citations Open access
Semantic Scholar
Septic Shock due to Myroides odoratus in a medical intensive care unit patient with severe necrotising pancreatitis
T. Lahmer, A. Beitz, U. Ehmer, Roland M. Schmid +1 more
2016Anaesthesia and Intensive Care9 citations
Semantic Scholar
Obesity and NK cells affect the expression of the long form of the leptin receptor Ob-Rb in liver of F344 rats.
C. Wrann, U. Ehmer, A. Lautenbach, Susanne D. Kuhlmann +1 more
2010Experimental and Toxicological Pathology9 citations
Semantic Scholar
Secondary sclerosing cholangitis after COVID-19 pneumonia: a report of two cases and review of the literature
U. Bauer, D. Pavlova, Rami Abbassi, T. Lahmer +3 more
2022Clinical Journal of Gastroenterology8 citations Open access
Semantic Scholar
Isavuconazole and Liposomal Amphotericin B as Successful Combination Therapy of Refractory Invasive Candidiasis in a Liver Transplant Recipient: A Case Report and Literature Review
Georgios Odysseos, U. Mayr, G. Bozsaki, Christian Seidensticker +4 more
2021Mycopathologia8 citations Open access
Semantic Scholar
LBA37 IMMUTACE: A biomarker-orientated, multi center phase II AIO study of transarterial chemoembolization (TACE) in combination with nivolumab performed for intermediate stage hepatocellular carcinoma (HCC)
A. Vogel, A. Saborowski, J. Hinrichs, T. Ettrich +9 more
2021Annals of Oncology8 citations Open access
Semantic Scholar
Transjugular intrahepatic portosystemic shunt creation (TIPS) in the angio-CT-a hybrid intervention with image fusion.
Jonathan Nadjiri, T. Waggershauser, M. Mühlmann, U. Ehmer +4 more
2023European Radiology7 citations Open access
Semantic Scholar
Liver transplantation versus watchful waiting in hepatocellular carcinoma patients with complete response to bridging therapy – a retrospective observational study
M. Schoenberg, U. Ehmer, A. Umgelter, J. Bucher +10 more
2020Transplant International7 citations Open access
Semantic Scholar
Fulminant Liver Failure after Treatment with a Checkpoint Inhibitor for Gastric Cancer: A Case Report and Review of the Literature
Miriam Dibos, J. Dumoulin, Carolin Mogler, S. Wunderlich +6 more
2023Journal of Clinical Medicine6 citations Open access
Semantic Scholar
An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes
Eric K. Hubner, C. Lechler, B. Kohnke-Ertel, Anne-Flore Zmoos +3 more
2017Journal of Gene Medicine2 citations Open access
Semantic Scholar
Regional transplant rates depend more on physician-dependent variables than on proximity to transplant center
E. Payani, N. Börner, Dionysios Kolliogiannis, S. Brunner +8 more
2023Langenbeck's archives of surgery (Print)1 citations Open access
Semantic Scholar
535 FXR-MEDIATED REGULATION OF THE HUMAN HEPATIC BILE ACID UDP-GLUCURONOSYLTRANSFERASE (UGT) 1A3 GENE IN CHOLESTASIS
T. Erichsen, A. Aehlen, U. Ehmer, T. Lankisch +2 more
20081 citations Open access
Semantic Scholar
Identification of two functional polymorphisms of the human hepatic Ugtla4 gene: Implications for drug therapy and genetic disease predisposition
U. Ehmer, A. Vogel, A. Barut, M. Manns +1 more
20031 citations
Semantic Scholar
238 High frequency of single nucleotide polymorphisms (SNPS) at the human UGT1A gene locus: differential alterations of glucuronidation of two novel SNPS of the hepatic UGT1A4 gene
U. Ehmer, A. Vogel, A. Barut, Britta Bleidistel +2 more
20031 citations
Semantic Scholar

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