Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

I. Spiteri · SciRah

Researcher profile · Semantic Scholar

I. Spiteri

Share profile

I. Spiteri — researcher profile on SciRah

h-index: 27
Works: 50
Citations: 7,821

Most-cited papers

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
G. Vlachogiannis, S. Hedayat, A. Vatsiou, Y. Jamin +39 more
2018Science1,887 citations Open access
Semantic Scholar
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
A. Sottoriva, I. Spiteri, S. Piccirillo, Anestis Touloumis +5 more
2013Proceedings of the National Academy of Sciences of the United States of America1,722 citations Open access
Semantic Scholar
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
C. Blenkiron, Leonard D. Goldstein, Natalie Thorne, I. Spiteri +9 more
2007Genome Biology1,020 citations Open access
Semantic Scholar
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.
A. Lujambio, S. Ropero, E. Ballestar, M. Fraga +11 more
2007Cancer Research978 citations
Semantic Scholar
Longitudinal liquid biopsy and mathematical modelling of clonal evolution forecast waiting time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
K. Khan, D. Cunningham, B. Werner, G. Vlachogiannis +32 more
2018Cancer Discovery202 citations Open access
Semantic Scholar
Phenotypic plasticity and genetic control in colorectal cancer evolution
J. Househam, Timon Heide, George D. Cresswell, I. Spiteri +29 more
2021bioRxiv165 citations Open access
Semantic Scholar
Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping
J. Abraham, M. Maranian, I. Spiteri, R. Russell +6 more
2012BMC Medical Genomics165 citations Open access
Semantic Scholar
Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: an expression profile study.
L. Tracey, R. Villuendas, A. Dotor, I. Spiteri +5 more
2003Blood159 citations
Semantic Scholar
Characterisation of microRNA expression in post-natal mouse mammary gland development
Stefanie Avril-Sassen, Leonard D. Goldstein, J. Stingl, C. Blenkiron +7 more
2009BMC Genomics130 citations Open access
Semantic Scholar
Identification of genes involved in resistance to interferon-alpha in cutaneous T-cell lymphoma.
L. Tracey, R. Villuendas, P. Ortiz, A. Dopazo +11 more
2002American Journal of Pathology118 citations Open access
Semantic Scholar
The co-evolution of the genome and epigenome in colorectal cancer
Timon Heide, J. Househam, George D. Cresswell, I. Spiteri +27 more
2021bioRxiv111 citations Open access
Semantic Scholar
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A. Acar, D. Nichol, J. Fernández-Mateos, George D. Cresswell +15 more
2020Nature Communications111 citations Open access
Semantic Scholar
The pitfalls of platform comparison: DNA copy number array technologies assessed
C. Curtis, A. Lynch, M. Dunning, I. Spiteri +6 more
2009BMC Genomics109 citations Open access
Semantic Scholar
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.
E. Eskilsson, G. Røsland, K. M. Talasila, S. Knappskog +27 more
2016Neuro-Oncology104 citations Open access
Semantic Scholar
Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence
H. Ellis, M. Greenslade, B. Powell, I. Spiteri +2 more
2015Frontiers in Oncology100 citations Open access
Semantic Scholar
Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization
A. Sottoriva, I. Spiteri, D. Shibata, C. Curtis +1 more
2012Cancer Research79 citations Open access
Semantic Scholar
Evolutionary dynamics of residual disease in human glioblastoma
I. Spiteri, G. Caravagna, George D. Cresswell, A. Vatsiou +12 more
2018Annals of Oncology77 citations Open access
Semantic Scholar
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype
B. Lupo, F. Sassi, M. Pinnelli, F. Galimi +28 more
2020Science Translational Medicine75 citations Open access
Semantic Scholar
Measuring single cell divisions in human tissues from multi-region sequencing data
B. Werner, Jack Case, Marc J. Williams, K. Chkhaidze +11 more
2020Nature Communications74 citations Open access
Semantic Scholar
Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone
S. Piccirillo, I. Spiteri, A. Sottoriva, Anestis Touloumis +11 more
2014Cancer Research64 citations Open access
Semantic Scholar
Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia
M. Gubernator, Sadie C. Slater, H. Spencer, I. Spiteri +19 more
2015Arteriosclerosis, Thrombosis and Vascular Biology47 citations Open access
Semantic Scholar
Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast
Ana-Teresa Maia, I. Spiteri, Alvin J. X. Lee, Martin O’Reilly +3 more
2009Breast Cancer Research42 citations Open access
Semantic Scholar
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
George D. Cresswell, D. Nichol, I. Spiteri, Haider Tari +8 more
2020Nature Communications37 citations Open access
Semantic Scholar
The spatio-temporal evolution of lymph node spread in early breast cancer
P. Barry, A. Vatsiou, I. Spiteri, D. Nichol +21 more
2018Clinical Cancer Research35 citations Open access
Semantic Scholar
Calpastatin is associated with lymphovascular invasion in breast cancer.
S. Storr, R. Mohammed, C. Woolston, A. Green +6 more
2011Breast35 citations Open access
Semantic Scholar
Transcriptional Response of T Cells to IFN-α: Changes Induced in IFN-α-Sensitive and Resistant Cutaneous T Cell Lymphoma
L. Tracey, I. Spiteri, P. Ortiz, M. Lawler +2 more
200428 citations
Semantic Scholar
CD15 Expression Does Not Identify a Phenotypically or Genetically Distinct Glioblastoma Population
E. Kenney-Herbert, Talal M. Fael Al-Mayhani, S. Piccirillo, Joanna C. Fowler +3 more
2015Stem Cells Translational Medicine27 citations Open access
Semantic Scholar
PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
Anna Git, I. Spiteri, C. Blenkiron, M. Dunning +6 more
2008Breast Cancer Research27 citations Open access
Semantic Scholar
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer
H. Lote, I. Spiteri, L. Ermini, A. Vatsiou +26 more
2017Annals of Oncology26 citations Open access
Semantic Scholar
Longitudinal liquid biopsy and mathematical modelling of clonal evolution forecast waiting time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
K. Khan, D. Cunningham, Benjamin Werner, G. Vlachogiannis +34 more
201917 citations
Semantic Scholar
Abstract 5016: The human sub-ependymal zone harbors glioblastoma precursors and represents a distinct therapeutic target.
S. Piccirillo, I. Spiteri, A. Sottoriva, Anestis Touloumis +10 more
201316 citations
Semantic Scholar
HES5 silencing is an early and recurrent change in prostate tumourigenesis
C. Massie, I. Spiteri, H. Ross-Adams, Hayley J. Luxton +12 more
2015Endocrine-Related Cancer13 citations Open access
Semantic Scholar
Transcriptional response of T cells to IFN-alpha: changes induced in IFN-alpha-sensitive and resistant cutaneous T cell lymphoma.
L. Tracey, I. Spiteri, P. Ortiz, M. Lawler +2 more
2004Journal of Interferon and Cytokine Research13 citations
Semantic Scholar
Exploiting evolutionary herding to control drug resistance in cancer
A. Acar, D. Nichol, J. Fernández-Mateos, George D. Cresswell +12 more
2019bioRxiv12 citations Open access
Semantic Scholar
Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer
W. Cross, S. Nowinski, George D. Cresswell, M. Mossner +49 more
2020bioRxiv5 citations Open access
Semantic Scholar
Measuring single cell divisions in human cancers from multi-region sequencing data
B. Werner, Jack Case, Marc J. Williams, K. Chkhaidze +11 more
2019bioRxiv3 citations Open access
Semantic Scholar
Intratumor heterogeneity and transcriptional profiling in glioblastoma: translational opportunities
S. Piccirillo, I. Spiteri
20153 citations Open access
Semantic Scholar
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data
Timon Heide, J. Househam, George D. Cresswell, I. Spiteri +28 more
2021bioRxiv1 citations Open access
Semantic Scholar
COMPLEX EVOLUTIONARY DYNAMICS GENERATES GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN INDIVIDUAL PATIENTS WITH GLIOBLASTOMA
C. Watts, S. Piccirillo, I. Spiteri, A. Sottoriva +4 more
20141 citations Open access
Semantic Scholar
in Human Cancer Cells Genetic Unmasking of an Epigenetically Silenced microRNA
A. Lujambio, S. Ropero, E. Ballestar, M. Fraga +11 more
20071 citations
Semantic Scholar
253e IMMUNE EDITING IN THE INVASIVE MARGIN AND NODE DEPOSITS OF COLORECTAL CANCER SELECTS FOR CELLULAR NEIGHBOURHOODS ENRICHED IN PDL1+ CANCER CELLS
V. Gunasri, Eszter Lakatos, N. Trahearn, Luis H Cisneros +20 more
2023Gastroenterology0 citations
Semantic Scholar
O47 Spatially resolving the dynamics of immune escape in advanced colorectal cancer
V. Gunasri, Eszter Lakatos, N. Trahearn, Luis H Cisneros +16 more
2023Oral presentations0 citations
Semantic Scholar
Abstract IA04: Understanding tumor heterogeneity in glioblastoma
S. Tavaré, A. Sottoriva, S. Piccirillo, I. Spiteri +4 more
20150 citations
Semantic Scholar
O11TRANSCRIPTIONAL PROFILING OF DISTINCT COMPARTMENTS IN HUMAN GLIOBLASTOMA REVEALS KEY DYSREGULATED PATHWAYS
S. Piccirillo, I. Spiteri, A. Sottoriva, Anestis Touloumis +4 more
20140 citations Open access
Semantic Scholar
O4.05GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN HUMAN GLIOBLASTOMA
S. Piccirillo, I. Spiteri, A. Sottoriva, Anestis Touloumis +5 more
20140 citations Open access
Semantic Scholar
O039 The interferonscape: Systems biology of interferon stimulated pathways and networks
S. Samarajiwa, I. Spiteri, A. Lynch, A. Jauhiainen +4 more
20120 citations
Semantic Scholar
Abstract 3342: Tumor-initiating cells in human glioblastoma are heterogeneous populations which reside in distinct environmental niches
S. Piccirillo, I. Spiteri, A. Sottoriva, Nicholas F. Marko +3 more
20120 citations
Semantic Scholar
Profiles and Cancer Stem Cell Organization Single-Molecule Genomic Data Delineate Patient-Specific Tumor
A. Sottoriva, I. Spiteri, D. Shibata, C. Curtis
20120 citations
Semantic Scholar
PS1-022. The InterferonScape: An insight into the Integrative Systems Biology of Interferon Stimulated Genes
Andy Lynch Shamith Samarajiwa, I. Spiteri, Mike L. Smith, C. Caldas +2 more
20110 citations
Semantic Scholar
Farmacogenómica: ¿Equilibrio entre ciencia y ética?
L. Tracey, I. Spiteri, Miguel Ángel Piris Pinilla
20020 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. Sottoriva×31
Invite
A. Sottoriva — researcher profile on SciRah
S. Tavaré×15
Invite
S. Tavaré — researcher profile on SciRah
George D. Cresswell×13
Invite
George D. Cresswell — researcher profile on SciRah
S. Piccirillo×11
Invite
S. Piccirillo — researcher profile on SciRah

×11

Invite

D. Nichol — researcher profile on SciRah

Invite

C. Curtis — researcher profile on SciRah

Invite

C. Watts — researcher profile on SciRah

Invite

C. Caldas — researcher profile on SciRah

Invite

Timon Heide — researcher profile on SciRah

Invite

T. Graham — researcher profile on SciRah

J. Fernández-Mateos×8

Invite

J. Fernández-Mateos — researcher profile on SciRah

Anestis Touloumis×8

Invite

Anestis Touloumis — researcher profile on SciRah