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George D. Cresswell · SciRah

Researcher profile · Semantic Scholar

George D. Cresswell

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George D. Cresswell — researcher profile on SciRah

h-index: 17
Works: 43
Citations: 1,447

Most-cited papers

Pervasive chromosomal instability and karyotype order in tumour evolution
T. Watkins, Emilia L. Lim, Marina Petković, S. Elizalde +51 more
2020Nature331 citations Open access
Semantic Scholar
Phenotypic plasticity and genetic control in colorectal cancer evolution
J. Househam, Timon Heide, George D. Cresswell, I. Spiteri +29 more
2021bioRxiv165 citations Open access
Semantic Scholar
Subclonal reconstruction of tumors using machine learning and population genetics
G. Caravagna, Timon Heide, Marc J. Williams, Luis Zapata +11 more
2020Nature Genetics119 citations Open access
Semantic Scholar
The co-evolution of the genome and epigenome in colorectal cancer
Timon Heide, J. Househam, George D. Cresswell, I. Spiteri +27 more
2021bioRxiv111 citations Open access
Semantic Scholar
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A. Acar, D. Nichol, J. Fernández-Mateos, George D. Cresswell +15 more
2020Nature Communications111 citations Open access
Semantic Scholar
Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications
George D. Cresswell, J. Apps, T. Chagtai, Borbála Mifsud +10 more
2016EBioMedicine78 citations Open access
Semantic Scholar
Evolutionary dynamics of residual disease in human glioblastoma
I. Spiteri, G. Caravagna, George D. Cresswell, A. Vatsiou +12 more
2018Annals of Oncology77 citations Open access
Semantic Scholar
Measuring single cell divisions in human tissues from multi-region sequencing data
B. Werner, Jack Case, Marc J. Williams, K. Chkhaidze +11 more
2020Nature Communications74 citations Open access
Semantic Scholar
Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells
D. Rosano, E. Sofyali, Heena Dhiman, Chiara Ghirardi +22 more
2024Cancer Discovery53 citations Open access
Semantic Scholar
EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers
E. Smyth, G. Vlachogiannis, S. Hedayat, Alice Harbery +29 more
2020Gut45 citations Open access
Semantic Scholar
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
George D. Cresswell, D. Nichol, I. Spiteri, Haider Tari +8 more
2020Nature Communications37 citations Open access
Semantic Scholar
Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm
Erica A. Oliveira, S. Milite, J. Fernández-Mateos, George D. Cresswell +16 more
2025Cancer Research35 citations Open access
Semantic Scholar
The spatio-temporal evolution of lymph node spread in early breast cancer
P. Barry, A. Vatsiou, I. Spiteri, D. Nichol +21 more
2018Clinical Cancer Research35 citations Open access
Semantic Scholar
Somatic TP53 Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors
T. D. Treger, T. Chagtai, R. Butcher, George D. Cresswell +7 more
2018Translational Oncology27 citations Open access
Semantic Scholar
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer
J. Fernández-Mateos, George D. Cresswell, Nick Trahearn, K. Webb +23 more
2024Nature Cancer25 citations Open access
Semantic Scholar
A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations
Ingrid M. Saldana-Guerrero, L. F. Montaño-Gutierrez, Katy Boswell, C. Hafemeister +33 more
2024bioRxiv19 citations Open access
Semantic Scholar
Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation
Sophia M. Blake, Stefan H. Stricker, Hanna Halavach, A. Poetsch +7 more
2016eLife19 citations Open access
Semantic Scholar
Epigenetically driven and early immune evasion in colorectal cancer evolution
Eszter Lakatos, V. Gunasri, Luis Zapata, J. Househam +18 more
2025Nature Genetics16 citations Open access
Semantic Scholar
Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States
Sally L. George, Claire Lynn, Reda Stankunaite, Debbie Hughes +50 more
2024Cancer Discovery16 citations Open access
Semantic Scholar
Exploiting evolutionary herding to control drug resistance in cancer
A. Acar, D. Nichol, J. Fernández-Mateos, George D. Cresswell +12 more
2019bioRxiv12 citations Open access
Semantic Scholar
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
I. Al Bakir, K. Curtius, George D. Cresswell, H. Grant +21 more
2025Gut11 citations Open access
Semantic Scholar
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer.
Elena Grassi, V. Vurchio, George D. Cresswell, Irene Catalano +22 more
2025Science Translational Medicine7 citations Open access
Semantic Scholar
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer
Eszter Lakatos, V. Gunasri, Luis Zapata, J. Househam +18 more
2024bioRxiv7 citations Open access
Semantic Scholar
Model-based tumor subclonal reconstruction
G. Caravagna, Timon Heide, Marc J. Williams, Luis Zapata +10 more
2019bioRxiv6 citations Open access
Semantic Scholar
Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping
Erica Oliveira, S. Milite, J. Fernández-Mateos, George D. Cresswell +16 more
2024bioRxiv5 citations Open access
Semantic Scholar
Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer
W. Cross, S. Nowinski, George D. Cresswell, M. Mossner +49 more
2020bioRxiv5 citations Open access
Semantic Scholar
Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer
W. Cross, S. Nowinski, George D. Cresswell, M. Mossner +50 more
2026Cancer Discovery4 citations Open access
Semantic Scholar
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer
Elena Grassi, V. Vurchio, George D. Cresswell, Irene Catalano +16 more
2024bioRxiv3 citations Open access
Semantic Scholar
Measuring single cell divisions in human cancers from multi-region sequencing data
B. Werner, Jack Case, Marc J. Williams, K. Chkhaidze +11 more
2019bioRxiv3 citations Open access
Semantic Scholar
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data
Timon Heide, J. Househam, George D. Cresswell, I. Spiteri +28 more
2021bioRxiv1 citations Open access
Semantic Scholar
Somatic TP 53 Mutations in Anaplastic Wilms Tumor
T. D. Treger, T. Chagtai, R. Butcher, George D. Cresswell +7 more
20191 citations
Semantic Scholar
259: GENOMIC BIOMARKER FROM SHALLOW WHOLE GENOME SEQUENCING PREDICTS FUTURE HIGH-GRADE DYSPLASIA AND COLORECTAL CANCER IN ULCERATIVE COLITIS
I. Al Bakir, George D. Cresswell, H. Grant, N. Nasreddin +19 more
2025Gastroenterology0 citations Open access
Semantic Scholar
Abstract A036 The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states
Sally L. George, Claire Lynn, Reda Stankunaite, Debbie Hughes +26 more
2024Cancer Research0 citations
Semantic Scholar
Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
George D. Cresswell, T. Chagtai, R. Al-Saadi, T. D. Treger +7 more
2024bioRxiv0 citations Open access
Semantic Scholar
Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis
I. Al Bakir, K. Curtius, George D. Cresswell, H. Grant +21 more
2024medRxiv0 citations Open access
Semantic Scholar
253e IMMUNE EDITING IN THE INVASIVE MARGIN AND NODE DEPOSITS OF COLORECTAL CANCER SELECTS FOR CELLULAR NEIGHBOURHOODS ENRICHED IN PDL1+ CANCER CELLS
V. Gunasri, Eszter Lakatos, N. Trahearn, Luis H Cisneros +20 more
2023Gastroenterology0 citations
Semantic Scholar
O47 Spatially resolving the dynamics of immune escape in advanced colorectal cancer
V. Gunasri, Eszter Lakatos, N. Trahearn, Luis H Cisneros +16 more
2023Oral presentations0 citations
Semantic Scholar
Abstract A045: Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer
A. Berner, C. Gabbutt, S. Nowinski, J. Househam +10 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PR06: Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
S. Nowinski, W. Cross, M. Mossner, George D. Cresswell +20 more
2020Oral Presentations - Proffered Abstracts0 citations
Semantic Scholar
Model-based tumor subclonal 1 reconstruction 2
G. Caravagna, Timon Heide, Marc J. Williams, Luis Zapata +11 more
20200 citations
Semantic Scholar
A Genomic Study of the Evolution of Paediatric Solid Tumours
George D. Cresswell
20180 citations
Semantic Scholar
Author response: Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation
Sophia M. Blake, Stefan H. Stricker, Hanna Halavach, A. Poetsch +7 more
20160 citations Open access
Semantic Scholar
subtype specific cancer evolution and epigenetic states
Sally L. George, Claire Lynn, Reda Stankunaite, Debbie Hughes +48 more
0 citations
Semantic Scholar

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