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K. Ulbrich · SciRah

Researcher profile · Semantic Scholar

K. Ulbrich

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K. Ulbrich — researcher profile on SciRah

h-index: 65
Works: 288
Citations: 16K

Most-cited papers

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies.
K. Ulbrich, Kateřina Holá, V. Šubr, A. Bakandritsos +2 more
2016Chemical Reviews1,494 citations Open access
Semantic Scholar
Passive vs. Active Tumor Targeting using RGD-and NGR-modified Polymeric Nanomedicines
S. Kunjachan, Robert Pola, F. Gremse, Benjamin Theek +10 more
2014Nano letters (Print)293 citations Open access
Semantic Scholar
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.
M. Talelli, M. Iman, Amir K. Varkouhi, C. Rijcken +7 more
2010Biomaterials260 citations
Semantic Scholar
Structural and chemical aspects of HPMA copolymers as drug carriers.
K. Ulbrich, V. Šubr
2010Advanced Drug Delivery Reviews178 citations
Semantic Scholar
Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.
T. Etrych, L. Kovář, J. Strohalm, P. Chytil +2 more
2011Journal of Controlled Release165 citations
Semantic Scholar
Nanomedicines for Inflammatory Arthritis: Head-To-Head Comparison of Glucocorticoid-Containing Polymers, Micelles and Liposomes
Ling-Dong Quan, Yijia Zhang, B. Crielaard, Anand Dusad +12 more
2013ACS Nano145 citations Open access
Semantic Scholar
HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.
T. Etrych, V. Šubr, J. Strohalm, M. Sirova +2 more
2012Journal of Controlled Release130 citations
Semantic Scholar
N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation.
P. Chytil, T. Etrych, J. Kr̆íž, V. Šubr +1 more
2010European Journal of Pharmaceutical Sciences129 citations
Semantic Scholar
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy.
M. Talelli, S. Oliveira, C. Rijcken, Ebel H. E. Pieters +6 more
2013Biomaterials124 citations Open access
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Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound
R. Carlisle, James J. Choi, M. Bazan-Peregrino, R. Laga +5 more
2013Journal of the National Cancer Institute122 citations Open access
Semantic Scholar
Non-Invasive Optical Imaging of Nanomedicine Biodistribution
S. Kunjachan, F. Gremse, Benjamin Theek, P. Koczera +7 more
2012ACS Nano110 citations Open access
Semantic Scholar
Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage.
Hideaki Nakamura, T. Etrych, P. Chytil, Manami Ohkubo +3 more
2014Journal of Controlled Release97 citations
Semantic Scholar
Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting.
T. Etrych, J. Strohalm, P. Chytil, P. Černoch +3 more
2011European Journal of Pharmaceutical Sciences94 citations
Semantic Scholar
HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases
H. Dozono, S. Yanazume, Hideaki Nakamura, T. Etrych +8 more
2016Targeted oncology85 citations
Semantic Scholar
pH-triggered block copolymer micelles based on a pH-responsive PDPA (poly[2-(diisopropylamino)ethyl methacrylate]) inner core and a PEO (poly(ethylene oxide)) outer shell as a potential tool for the cancer therapy
F. Giacomelli, P. Štěpánek, C. Giacomelli, Vanessa Schmidt +3 more
201185 citations
Semantic Scholar
Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide–Generating Agents Improves the Therapeutic Effects of Nanomedicines
Waliul Islam, Jun Fang, T. Imamura, T. Etrych +3 more
2018Molecular Cancer Therapeutics76 citations
Semantic Scholar
Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.
T. Etrych, V. Šubr, R. Laga, B. Říhová +1 more
2014European Journal of Pharmaceutical Sciences67 citations
Semantic Scholar
HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release.
P. Chytil, E. Koziolová, T. Etrych, K. Ulbrich
2018Macromolecular Bioscience65 citations Open access
Semantic Scholar
HPMA copolymers: 30 years of advances.
T. Lammers, K. Ulbrich
2010Advanced Drug Delivery Reviews65 citations
Semantic Scholar
Polymer coatings for delivery of nucleic acid therapeutics.
R. Laga, R. Carlisle, M. Tangney, K. Ulbrich +1 more
2012Journal of Controlled Release64 citations Open access
Semantic Scholar
Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging.
Stefan Hoffmann, Lucie Vystrčilová, K. Ulbrich, T. Etrych +3 more
2012Biomacromolecules62 citations
Semantic Scholar
Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin.
Y. Chen, O. Tezcan, D. Li, N. Beztsinna +6 more
2017Nanoscale61 citations Open access
Semantic Scholar
Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo.
Hideaki Nakamura, Long Liao, Yuki Hitaka, K. Tsukigawa +4 more
2013Journal of Controlled Release60 citations
Semantic Scholar
Overcoming cellular multidrug resistance using classical nanomedicine formulations.
S. Kunjachan, Andrzej Błauż, D. Möckel, Benjamin Theek +8 more
2012European Journal of Pharmaceutical Sciences60 citations
Semantic Scholar
Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester.
Eliézer Jäger, A. Jäger, P. Chytil, T. Etrych +4 more
2013Journal of Controlled Release59 citations
Semantic Scholar
Novel “soft” biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system
A. Jäger, D. Gromadzki, Eliézer Jäger, F. Giacomelli +7 more
201256 citations
Semantic Scholar
Poly[N-(2-hydroxypropyl)methacrylamide]-based tissue-embedding medium compatible with MALDI mass spectrometry imaging experiments.
Martin Strohalm, J. Strohalm, Filip Kaftan, Lukas Krasny +4 more
2011Analytical Chemistry55 citations
Semantic Scholar
Spectral analysis of doxorubicin accumulation and the indirect quantification of its DNA intercalation.
O. Hovorka, V. Šubr, D. Větvička, L. Kovář +6 more
2010European journal of pharmaceutics and biopharmaceutics53 citations
Semantic Scholar
Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents
Jun Fang, Rayhanul Islam, Waliul Islam, Hongzhuan Yin +4 more
2019Pharmaceutics52 citations Open access
Semantic Scholar
Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics.
M. Pechar, Robert Pola, R. Laga, K. Ulbrich +6 more
2011Biomacromolecules49 citations
Semantic Scholar
Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system.
Sergey K. Filippov, P. Chytil, P. Konarev, M. Dyakonova +7 more
2012Biomacromolecules46 citations
Semantic Scholar
Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications.
Eliézer Jäger, Anita Höcherl, O. Janoušková, A. Jäger +7 more
2016Nanoscale44 citations Open access
Semantic Scholar
Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution.
P. Chytil, Stefan Hoffmann, L. Schindler, L. Kostka +5 more
2013Journal of Controlled Release44 citations
Semantic Scholar
Polymer conjugates of acridine-type anticancer drugs with pH-controlled activation.
O. Sedláček, M. Hrubý, M. Studenovsky, D. Větvička +4 more
2012Bioorganic & Medicinal Chemistry43 citations
Semantic Scholar
Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice.
Hideaki Nakamura, E. Koziolová, T. Etrych, P. Chytil +3 more
2015European journal of pharmaceutics and biopharmaceutics41 citations
Semantic Scholar
Biodegradable Micellar HPMA-Based Polymer-Drug Conjugates with Betulinic Acid for Passive Tumor Targeting.
E. A. Lomkova, P. Chytil, O. Janoušková, T. Mueller +7 more
2016Biomacromolecules39 citations
Semantic Scholar
Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study.
Sergey K. Filippov, J. M. Franklin, P. Konarev, P. Chytil +8 more
2013Biomacromolecules39 citations Open access
Semantic Scholar
Polymer therapeutics with a coiled coil motif targeted against murine bcl1 leukemia.
Robert Pola, R. Laga, K. Ulbrich, I. Sieglová +5 more
2013Biomacromolecules39 citations
Semantic Scholar
Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics.
R. Laga, O. Janoušková, K. Ulbrich, Robert Pola +4 more
2015Biomacromolecules38 citations
Semantic Scholar
Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin.
Hideaki Nakamura, E. Koziolová, P. Chytil, K. Tsukigawa +5 more
2016Molecular Pharmaceutics37 citations
Semantic Scholar
Self-assembly of biodegradable copolyester and reactive HPMA-based polymers into nanoparticles as an alternative stealth drug delivery system
Eliézer Jäger, A. Jäger, T. Etrych, F. Giacomelli +6 more
201237 citations
Semantic Scholar
Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.
G. Lynn, P. Chytil, J. Francica, Anna Lagová +14 more
2019Biomacromolecules36 citations
Semantic Scholar
The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
B. Tomalová, M. Sirova, P. Rossmann, Robert Pola +9 more
2016Journal of Controlled Release36 citations
Semantic Scholar
iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties
P. Šácha, Tomáš Knedlík, J. Schimer, J. Tykvart +9 more
2016Angewandte Chemie36 citations Open access
Semantic Scholar
Synthesis of Well-Defined Semitelechelic Poly[N-(2-hydroxypropyl)methacrylamide] Polymers with Functional Group at the α-End of the Polymer Chain by RAFT Polymerization
V. Šubr, L. Kostka, J. Strohalm, T. Etrych +1 more
201336 citations
Semantic Scholar
Synthesis and Properties of Star HPMA Copolymer Nanocarriers Synthesised by RAFT Polymerisation Designed for Selective Anticancer Drug Delivery and Imaging.
P. Chytil, E. Koziolová, O. Janoušková, L. Kostka +2 more
2015Macromolecular Bioscience35 citations
Semantic Scholar
Click chemistry as a powerful and chemoselective tool for the attachment of targeting ligands to polymer drug carriers
Robert Pola, A. Braunova, R. Laga, M. Pechar +1 more
201435 citations
Semantic Scholar
Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo
Jan-Michael Prill, V. Šubr, N. Pasquarelli, Tatjana Engler +4 more
2014PLoS ONE34 citations Open access
Semantic Scholar
Coiled coil peptides and polymer-peptide conjugates: synthesis, self-assembly, characterization and potential in drug delivery systems.
M. Pechar, Robert Pola, R. Laga, A. Braunova +5 more
2014Biomacromolecules34 citations
Semantic Scholar
Hydrolytically Degradable Polymer Micelles for Anticancer Drug Delivery to Solid Tumors
P. Chytil, T. Etrych, L. Kostka, K. Ulbrich
201234 citations
Semantic Scholar

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