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I. Kirsch · SciRah

Researcher profile · Semantic Scholar

I. Kirsch

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I. Kirsch — researcher profile on SciRah

h-index: 57
Works: 155
Citations: 12K

Most-cited papers

A physical map of the human genome
J. Mcpherson, Marco A. Marra, L. Hillier, R. Waterston +109 more
2001Nature827 citations Open access
Semantic Scholar
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
G. Tonon, S. Modi, Li-Zi Wu, A. Kubo +8 more
2003Nature Genetics505 citations Open access
Semantic Scholar
Genetics and Cytogenetics of Multiple Myeloma
R. Fonseca, B. Barlogie, R. Bataille, C. Bastard +13 more
2004Cancer Research485 citations
Semantic Scholar
Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study.
George P. Kim, L. Colangelo, H. S. Wieand, S. Paik +3 more
2007Journal of Clinical Oncology345 citations
Semantic Scholar
Integration of cytogenetic landmarks into the draft sequence of the human genome
The BAC Resource Consortium, V. Cheung, N. Nowak, W. Jang +57 more
2001Nature327 citations Open access
Semantic Scholar
Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study.
Carmen J. Allegra, S. Paik, L. Colangelo, A. Parr +6 more
2003Journal of Clinical Oncology323 citations
Semantic Scholar
Karyotypic complexity of the NCI-60 drug-screening panel.
A. Roschke, G. Tonon, Kristen S Gehlhaus, Nicolas McTyre +5 more
2003Cancer Research289 citations
Semantic Scholar
Distinguishing right from left colon by the pattern of gene expression.
O. Glebov, L. Rodriguez, K. Nakahara, J. Jenkins +14 more
2003Cancer Epidemiology, Biomarkers and Prevention289 citations
Semantic Scholar
Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report
R. Fonseca, B. Barlogie, R. Bataille, C. Bastard +13 more
2004264 citations
Semantic Scholar
The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers.
E. Zudaire, N. Cuesta, V. Murty, K. Woodson +9 more
2008Journal of Clinical Investigation224 citations Open access
Semantic Scholar
High-throughput pairing of T cell receptor α and β sequences
B. Howie, A. Sherwood, Ashley D. Berkebile, J. Berka +7 more
2015Science Translational Medicine220 citations
Semantic Scholar
Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma.
A. Rook, J. Gelfand, M. Wysocka, A. Troxel +9 more
2015Blood212 citations Open access
Semantic Scholar
TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL
I. Kirsch, R. Watanabe, J. O'Malley, David W. Williamson +10 more
2015Science Translational Medicine210 citations Open access
Semantic Scholar
Measurable residual disease detection by high-throughput sequencing improves risk stratification for pediatric B-ALL.
B. Wood, David Wu, Beryl Crossley, Yunfeng Dai +13 more
2018Blood201 citations Open access
Semantic Scholar
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing &agr;&bgr; T cell clones
Tiago R. Matos, J. O'Malley, E. Lowry, D. Hamm +5 more
2017Journal of Clinical Investigation180 citations Open access
Semantic Scholar
Genetic counseling and testing in families with hereditary nonpolyposis colorectal cancer.
D. Hadley, J. Jenkins, E. Dimond, K. Nakahara +4 more
2003Archives of Internal Medicine177 citations
Semantic Scholar
Detection of minimal residual disease in B lymphoblastic leukemia by high-throughput sequencing of IGH
David Wu, R. Emerson, A. Sherwood, M. Loh +9 more
2014Clinical Cancer Research149 citations Open access
Semantic Scholar
Colon cancer screening practices after genetic counseling and testing for hereditary nonpolyposis colorectal cancer.
D. Hadley, J. Jenkins, E. Dimond, Márcia Cardim de Carvalho +2 more
2004Journal of Clinical Oncology149 citations
Semantic Scholar
Analysis of the V(D)J Recombination Efficiency at Lymphoid Chromosomal Translocation Breakpoints*
S. Raghavan, I. Kirsch, M. Lieber
2001Journal of Biological Chemistry148 citations Open access
Semantic Scholar
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
G. Tonon, S. Modi, Li-Zi Wu, A. Kubo +8 more
2003Nature Genetics147 citations Open access
Semantic Scholar
Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes.
A. Coxon, E. Rozenblum, Yoonsoo Park, N. Joshi +4 more
2005Cancer Research144 citations Open access
Semantic Scholar
Analytical evaluation of the clonoSEQ Assay for establishing measurable (minimal) residual disease in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple myeloma
T. Ching, M. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter +17 more
2020BMC Cancer140 citations Open access
Semantic Scholar
Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability.
A. Roschke, Kristen Stover, G. Tonon, A. Schäffer +1 more
2002Neoplasia119 citations Open access
Semantic Scholar
High-Throughput Sequencing of the T cell Receptor β gene identifies aggressive early-stage Mycosis Fungoides
A. de Masson, J. O'Malley, C. Elco, S. Garcia +11 more
2018Science Translational Medicine113 citations Open access
Semantic Scholar
The interactive online SKY/M‐FISH & CGH Database and the Entrez Cancer Chromosomes search database: Linkage of chromosomal aberrations with the genome sequence
T. Knutsen, Vasuki Gobu, R. Knaus, H. Padilla-Nash +5 more
2005Genes, Chromosomes and Cancer94 citations Open access
Semantic Scholar
Randomized comparison of group versus individual genetic education and counseling for familial breast and/or ovarian cancer.
K. Calzone, S. Prindiville, Oxana Jourkiv, J. Jenkins +8 more
2005Journal of Clinical Oncology90 citations
Semantic Scholar
The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications
K. Anderson, D. Auclair, G. Kelloff, C. Sigman +26 more
2017Clinical Cancer Research86 citations Open access
Semantic Scholar
CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma.
John H. Baird, M. Frank, Juliana K. Craig, Shabnum Patel +29 more
2020Blood77 citations Open access
Semantic Scholar
A rhodium(III) complex for high-affinity DNA base-pair mismatch recognition
H. Junicke, J. Hart, J. Kisko, O. Glebov +2 more
2003Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Randomized comparison of phone versus in-person BRCA1/2 predisposition genetic test result disclosure counseling
J. Jenkins, K. Calzone, E. Dimond, D. Liewehr +6 more
2007Genetics in Medicine68 citations Open access
Semantic Scholar
Sil overexpression in lung cancer characterizes tumors with increased mitotic activity
A. Erez, M. Perelman, S. Hewitt, Gadi Cojacaru +11 more
2004Oncogene67 citations Open access
Semantic Scholar
Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases.
Y. Hahn, T. Bera, Kristen S Gehlhaus, I. Kirsch +2 more
2004Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Genetic evidence that Sil is required for the sonic hedgehog response pathway
S. Izraeli, L. Lowe, Virginia L. Bertness, S. Campaner +3 more
2001Genesis62 citations
Semantic Scholar
Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping.
W. Reinhold, H. Kouros-Mehr, K. Kohn, A. Maunakea +11 more
2003Cancer Research58 citations
Semantic Scholar
Next generation sequencing in adult B cell acute lymphoblastic leukemia patients
O. S. Torra, M. Othus, David W. Williamson, B. Wood +7 more
2017Biology of Blood and Marrow Transplantation55 citations Open access
Semantic Scholar
DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators
J. Hart, O. Glebov, Russell J. Ernst, I. Kirsch +1 more
2006Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
High-throughput pairing of T cell receptor alpha and beta sequences (TECH2P.930)
A. Sherwood, B. Howie, Ashley D. Berkebile, J. Berka +8 more
2015Journal of Immunology51 citations
Semantic Scholar
The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr
A. Castiel, Michal Mark Danieli, Ahuvit David, Sharon Moshkovitz +5 more
2011Journal of Cell Science51 citations Open access
Semantic Scholar
Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration
K. Anderson, D. Auclair, S. Adam, A. Agarwal +46 more
2021Clinical Cancer Research49 citations Open access
Semantic Scholar
Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance.
A. Roschke, O. Glebov, S. Lababidi, Kristen S Gehlhaus +2 more
2008Neoplasia47 citations Open access
Semantic Scholar
Targeting Karyotypic Complexity and Chromosomal Instability of Cancer Cells
A. Roschke, I. Kirsch
2010Current Drug Targets44 citations Open access
Semantic Scholar
Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome.
D. Hadley, J. Jenkins, S. Steinberg, D. Liewehr +5 more
2008Journal of Clinical Oncology44 citations
Semantic Scholar
Sil Phosphorylation in a Pin1 Binding Domain Affects the Duration of the Spindle Checkpoint
S. Campaner, P. Kaldis, S. Izraeli, I. Kirsch
2005Molecular and Cellular Biology44 citations Open access
Semantic Scholar
A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome
I. Kirsch, Eric D. Green, R. Yonescu, R. Strausberg +13 more
2000Nature Genetics43 citations
Semantic Scholar
The SIL gene is essential for mitotic entry and survival of cancer cells.
A. Erez, A. Castiel, L. Trakhtenbrot, M. Perelman +8 more
2007Cancer Research42 citations
Semantic Scholar
Gene Expression Patterns Distinguish Colonoscopically Isolated Human Aberrant Crypt Foci from Normal Colonic Mucosa
O. Glebov, L. Rodriguez, P. Soballe, J. Denobile +3 more
2006Cancer Epidemiology, Biomarkers and Prevention39 citations Open access
Semantic Scholar
Predisposition to Arrhythmia and Autonomic Dysfunction in Nhlh1-Deficient Mice
T. Cogliati, D. Good, M. Haigney, Petra Delgado-Romero +3 more
2002Molecular and Cellular Biology38 citations Open access
Semantic Scholar
Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma
Bryan Rea, P. Haun, R. Emerson, M. Vignali +5 more
2018Journal of Clinical Pathology37 citations
Semantic Scholar
Gene expression differences in normal esophageal mucosa associated with regression and progression of mild and moderate squamous dysplasia in a high-risk Chinese population.
N. Joshi, L. L. Johnson, Wen-Qiang Wei, C. Abnet +7 more
2006Cancer Research35 citations Open access
Semantic Scholar
Multiple reciprocal translocations in salivary gland mucoepidermoid carcinomas.
G. Tonon, Kristen S Gehlhaus, R. Yonescu, F. Kaye +1 more
2004Cancer Genetics and Cytogenetics33 citations
Semantic Scholar

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