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L. Trakhtenbrot · SciRah

Researcher profile · Semantic Scholar

L. Trakhtenbrot

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L. Trakhtenbrot — researcher profile on SciRah

h-index: 27
Works: 127
Citations: 4,839

Most-cited papers

Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient
N. Amariglio, A. Hirshberg, B. Scheithauer, Y. Cohen +9 more
2009PLoS Medicine915 citations Open access
Semantic Scholar
The MLL recombinome of acute leukemias in 2017
C. Meyer, T. Burmeister, D. Gröger, G. Tsaur +67 more
2017Leukemia615 citations Open access
Semantic Scholar
The MLL recombinome of acute leukemias in 2013
C. Meyer, J. Hofmann, T. Burmeister, D. Gröger +83 more
2013Leukemia439 citations Open access
Semantic Scholar
New insights to the MLL recombinome of acute leukemias
C. Meyer, E. Kowarz, J. Hofmann, Aline Renneville +48 more
2009Leukemia436 citations
Semantic Scholar
A role for common fragile site induction in amplification of human oncogenes.
A. Hellman, Eitan Zlotorynski, S. Scherer, Joseph Cheung +4 more
2002Cancer Cell310 citations Open access
Semantic Scholar
Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells
Hilah Gal, N. Amariglio, L. Trakhtenbrot, J. Jacob-Hirsh +9 more
2006Leukemia155 citations Open access
Semantic Scholar
Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation.
O. Ashur-Fabian, A. Avivi, L. Trakhtenbrot, K. Adamsky +6 more
2004Proceedings of the National Academy of Sciences of the United States of America112 citations Open access
Semantic Scholar
Three‐dimensional spectral precision distance microscopy of chromatin nanostructures after triple‐colour DNA labelling: a study of the BCR region on chromosome 22 and the Philadelphia chromosome
Arif Esa, Peter Edelmann, G. Kreth, L. Trakhtenbrot +4 more
2000Journal of Microscopy111 citations
Semantic Scholar
Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene: expression profiling, resistance to interferon therapy, and poor prognosis.
Ninette Cohen, G. Rozenfeld-Granot, I. Hardan, F. Brok-Simoni +3 more
2001Cancer Genetics and Cytogenetics109 citations
Semantic Scholar
Immature Leukemic CD34+CXCR4+ Cells from CML Patients Have Lower Integrin‐Dependent Migration and Adhesion in Response to the Chemokine SDF‐1
A. Peled, I. Hardan, L. Trakhtenbrot, E. Gur +10 more
2002Stem Cells87 citations
Semantic Scholar
Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup
J. Soulier, L. Trakhtenbrot, Vesna Najfeld, J. M. Lipton +7 more
2003Leukemia80 citations Open access
Semantic Scholar
Philadelphia-Chromosome-Positive T-Lymphoblastic Leukemia: Acute Leukemia or Chronic Myelogenous Leukemia Blastic Crisis
P. Raanani, L. Trakhtenbrot, G. Rechavi, E. Rosenthal +6 more
2005Acta Haematologica70 citations
Semantic Scholar
Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF
Chaim Kaplinsky, L. Trakhtenbrot, I. Hardan, M. Reichart +5 more
2003Bone Marrow Transplantation48 citations Open access
Semantic Scholar
P53 in blind subterranean mole rats – loss-of-function versus gain-of-function activities on newly cloned Spalax target genes
A. Avivi, O. Ashur-Fabian, A. Joel, L. Trakhtenbrot +5 more
2007Oncogene47 citations Open access
Semantic Scholar
Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization.
Ninette Cohen, I. Novikov, I. Hardan, Arif Esa +5 more
2000Cancer Genetics and Cytogenetics46 citations
Semantic Scholar
Fluorescence lifetime imaging of DAPI‐stained nuclei as a novel diagnostic tool for the detection and classification of B‐cell chronic lymphocytic leukemia
Gilad Yahav, A. Hirshberg, O. Salomon, N. Amariglio +2 more
2016Cytometry Part A45 citations Open access
Semantic Scholar
Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet™) combined morphological and cytogenetical analysis
A. Shimoni, Arnon Nagler, Chaim Kaplinsky, M. Reichart +9 more
2002Leukemia44 citations Open access
Semantic Scholar
The SIL gene is essential for mitotic entry and survival of cancer cells.
A. Erez, A. Castiel, L. Trakhtenbrot, M. Perelman +8 more
2007Cancer Research42 citations
Semantic Scholar
Clonal expansion and not cell interconversion is the basis for the neuroblast and nonneuronal types of the SK-N-SH neuroblastoma cell line.
Ninette Cohen, D. Betts, G. Rechavi, N. Amariglio +1 more
2003Cancer Genetics and Cytogenetics37 citations
Semantic Scholar
Polyploidization of murine mesenchymal cells is associated with suppression of the long noncoding RNA H19 and reduced tumorigenicity.
Ofer Shoshani, H. Massalha, N. Shani, S. Kagan +6 more
2012Cancer Research35 citations Open access
Semantic Scholar
Assessment of the response to imatinib in chronic myeloid leukemia patients – comparison between the FISH, multiplex and RT‐PCR methods
P. Raanani, I. Ben-bassat, Shlomit Gan, L. Trakhtenbrot +7 more
2004European Journal of Haematology32 citations
Semantic Scholar
Translocation t(11;14) in newly diagnosed patients with multiple myeloma: Is it always favorable?
M. Leiba, Adrian Duek, N. Amariglio, A. Avigdor +11 more
2016Genes, Chromosomes and Cancer30 citations
Semantic Scholar
A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).
M. Koren-Michowitz, A. Shimoni, A. Vivante, L. Trakhtenbrot +5 more
2008Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis29 citations
Semantic Scholar
Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions.
A. Hirshberg, N. Yarom, N. Amariglio, R. Yahalom +6 more
2007Cancer Letters28 citations
Semantic Scholar
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII‐ and PI3K‐dependent mechanisms synergizing in leukemogenic rearrangements
Shahar Biechonski, D. Gourevich, Melanie Rall, N. Aqaqe +10 more
2017International Journal of Cancer27 citations Open access
Semantic Scholar
Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression.
L. Brodsky, J. Jacob-Hirsch, A. Avivi, L. Trakhtenbrot +7 more
2005Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Short Reduced Expression of Plakoglobin Correlates with Adverse Outcome in Patients with Neuroblastoma
Raya Amitay, D. Nass, D. Meitar, I. Goldberg +6 more
200125 citations
Semantic Scholar
Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia.
Rivka Yatuv, N. Rosenberg, A. Zivelin, H. Peretz +3 more
2001Blood25 citations
Semantic Scholar
Characterizing T Cells in SCID Patients Presenting with Reactive or Residual T Lymphocytes
A. Lev, A. Simon, L. Trakhtenbrot, I. Goldstein +5 more
2012Clinical and Developmental Immunology24 citations Open access
Semantic Scholar
Karyotypic evolution pathways in medulloblastoma/primitive neuroectodermal tumor determined with a combination of spectral karyotyping, G-banding, and fluorescence in situ hybridization.
Ninette Cohen, D. Betts, Uri Tavori, A. Toren +6 more
2004Cancer Genetics and Cytogenetics24 citations
Semantic Scholar
Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping (SKY)
Ninette Cohen, D. Betts, L. Trakhtenbrot, F. Niggli +4 more
2001Genes, Chromosomes and Cancer24 citations
Semantic Scholar
Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei.
Jutta Schwarz-Finsterle, S. Stein, Constance Groβmann, Eberhard Schmitt +5 more
2007Journal of Biochemical and Biophysical Methods23 citations
Semantic Scholar
Chromosomal Numerical Aberrations in Oral Lichen Planus
N. Yarom, T. Shani, N. Amariglio, S. Taicher +5 more
2009Journal of dentistry research21 citations
Semantic Scholar
COMBO‐FISH for focussed fluorescence labelling of gene domains: 3D‐analysis of the genome architecture of abl and bcr in human blood cells
Jutta Schwarz-Finsterle, S. Stein, C. Grossmann, Eberhard Schmitt +6 more
2005Cell Biology International19 citations
Semantic Scholar
Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia.
B. Bielorai, H. Golan, L. Trakhtenbrot, M. Reichart +6 more
2002Cancer Genetics and Cytogenetics18 citations
Semantic Scholar
SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis
Dhanoop Manikoth Ayyathan, Praveen Koganti, V. Marcu-Malina, T. Litmanovitch +4 more
2020Oncogene17 citations
Semantic Scholar
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer
Noa Rabinowicz, L. Mangala, K. Brown, Cintia Checa-Rodríguez +16 more
2017OncoTarget17 citations Open access
Semantic Scholar
Treatment with interferon alpha prior to discontinuation of imatinib in patients with chronic myeloid leukemia.
I. Hardan, A. Stanevsky, Yu. A. Volchek, T. Tohami +5 more
2012Cytokine17 citations
Semantic Scholar
Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma
L. Trakhtenbrot, I. Hardan, M. Koren-Michowitz, S. Oren +4 more
2010Genes, Chromosomes and Cancer17 citations
Semantic Scholar
Apaf1 in Chronic Myelogenous Leukemia (CML) Progression: Reduced Apaf1 Expression is Correlated with a H179R p53 Mutation During Clinical Blast Crisis
O. Ashur-Fabian, K. Adamsky, L. Trakhtenbrot, Y. Cohen +5 more
2007Cell Cycle17 citations Open access
Semantic Scholar
Determination of chromosome 13 status in bone marrow cells of patients with multiple myeloma using combined morphologic and fluorescence in situ hybridization analysis.
I. Hardan, R. Rothman, A. Gelibter, Ninette Cohen +8 more
2004Experimental Hematology16 citations Open access
Semantic Scholar
Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer.
T. Shani, A. Onn, Alaa Kabha, I. Ben-Dov +6 more
2010Oral Oncology15 citations
Semantic Scholar
Multiple Myeloma Presenting in Patients Younger than 50 Years of Age: A Single Institution Experience
Adrian Duek, L. Trakhtenbrot, A. Avigdor, A. Nagler +1 more
2020Acta Haematologica14 citations
Semantic Scholar
Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.
M. Koren-Michowitz, I. Hardan, Janina Berghoff, Galina Yshoev +4 more
2007Cancer Letters14 citations
Semantic Scholar
Co‐existence of multiple subclones in TEL‐AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1
R. Rothman, L. Trakhtenbrot, B. Bielorai, S. Izraeli +4 more
2005British Journal of Haematology14 citations
Semantic Scholar
Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients
B. Bielorai, L. Trakhtenbrot, N. Amariglio, R. Rothman +8 more
2004Bone Marrow Transplantation14 citations Open access
Semantic Scholar
The Multiparametric Scanning System for Evaluation of Minimal Residual Disease in Hematological Malignancies
L. Trakhtenbrot, G. Rechavi, N. Amariglio
2004Acta Haematologica14 citations
Semantic Scholar
The increased expression of 14q32 small nucleolar RNA transcripts in promyelocytic leukemia cells is not dependent on PML–RARA fusion gene
Yossi Cohen, K. Hertzog, O. Reish, M. Mashevich +4 more
2012Blood Cancer Journal13 citations Open access
Semantic Scholar
Co‐existence of clonal expanded autologous and transplacental‐acquired maternal T cells in recombination activating gene‐deficient severe combined immunodeficiency
A. Lev, A. Simon, J. Ben-ari, D. Takagi +6 more
2014Clinical and Experimental Immunology11 citations Open access
Semantic Scholar
SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia.
D. Betts, Racheli Stanchescu, F. Niggli, Ninette Cohen +3 more
2008Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis11 citations Open access
Semantic Scholar

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N. Amariglio×35
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N. Amariglio — researcher profile on SciRah
G. Rechavi×33
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G. Rechavi — researcher profile on SciRah
A. Nagler×11
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A. Nagler — researcher profile on SciRah
I. Hardan×11
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I. Hardan — researcher profile on SciRah

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Ninette Cohen — researcher profile on SciRah

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S. Izraeli — researcher profile on SciRah

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A. Toren — researcher profile on SciRah

F. Brok-Simoni×6

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F. Brok-Simoni — researcher profile on SciRah

A. Hirshberg×5

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A. Hirshberg — researcher profile on SciRah

M. Koren-Michowitz×5

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M. Koren-Michowitz — researcher profile on SciRah

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A. Avigdor — researcher profile on SciRah

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M. Reichart — researcher profile on SciRah