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P. Kaldis · SciRah

Researcher profile · Semantic Scholar

P. Kaldis

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P. Kaldis — researcher profile on SciRah

h-index: 53
Works: 194
Citations: 11K

Most-cited papers

Cdks, cyclins and CKIs: roles beyond cell cycle regulation
Shu-Hui Lim, P. Kaldis
2013Development1,433 citations Open access
Semantic Scholar
Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
C. S. Tan, K. Go, Xavier Bisteau, Lingyun Dai +10 more
2018Science204 citations Open access
Semantic Scholar
Modulation of Protein-Interaction States through the Cell Cycle.
Lingyun Dai, T. Zhao, Xavier Bisteau, Wendi Sun +5 more
2018Cell153 citations Open access
Semantic Scholar
Metabolic Remodeling during Liver Regeneration.
Matias J. Caldez, N. V. van Hul, H. Koh, X. Teo +13 more
2018Developmental Cell115 citations Open access
Semantic Scholar
Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis
Lakshmi Gopinathan, S. L. Tan, V. C. Padmakumar, V. Coppola +2 more
2014Cancer Research109 citations Open access
Semantic Scholar
IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice
D. Hodge, C. Berthet, V. Coppola, W. Kastenmüller +14 more
2014Journal of Autoimmunity108 citations Open access
Semantic Scholar
Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk
J. Sanches, Li-Na Zhao, A. Salehi, C. Wollheim +1 more
2021The FEBS Journal97 citations Open access
Semantic Scholar
Cell size control – a mechanism for maintaining fitness and function
Teemu P. Miettinen, Matias J. Caldez, P. Kaldis, Mikael Björklund
2017Bioessays82 citations Open access
Semantic Scholar
The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations
Xavier Bisteau, Matias J. Caldez, P. Kaldis
2014Cancers82 citations Open access
Semantic Scholar
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
Victor S. Tapia, Michael J. D. Daniels, Pablo Palazón-Riquelme, Matthew R. Dewhurst +7 more
2019Journal of Biological Chemistry73 citations Open access
Semantic Scholar
A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
A. Heijink, V. Blomen, Xavier Bisteau, F. Degener +4 more
2015Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation
Z. Tu, M. B. Bayazit, Hong-Bin Liu, Jing-Jing Zhang +13 more
2016Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
TLR3 agonist and Sorafenib combinatorial therapy promotes immune activation and controls hepatocellular carcinoma progression
Victor Ho, T. Lim, Justin C. Lee, Jeffrey D. Steinberg +6 more
2015OncoTarget64 citations Open access
Semantic Scholar
Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality
Radosław Szmyd, Joanna Niska-Blakie, M. Diril, Patrícia Renck Nunes +8 more
2018Oncogene63 citations Open access
Semantic Scholar
Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis
Li-Na Wang, Z. Tu, Chao Liu, Hong-Bin Liu +3 more
2018Cell Death and Differentiation60 citations Open access
Semantic Scholar
Emi2 Is Essential for Mouse Spermatogenesis
Lakshmi Gopinathan, Radoslaw Szmyd, D. Low, M. Diril +7 more
2017Cell Reports58 citations Open access
Semantic Scholar
Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential
Li-Na Zhao, Mikael Björklund, Matias J. Caldez, Jie Zheng +1 more
2021Oncogene53 citations
Semantic Scholar
Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan
Deepak Adhikari, Kiran Busayavalasa, Jing-Jing Zhang, Meng-Wen Hu +6 more
2016Cell Research44 citations Open access
Semantic Scholar
Cell cycle regulation in NAFLD: when imbalanced metabolism limits cell division
Matias J. Caldez, Mikael Bjorklund, P. Kaldis
2020Hepatology International43 citations Open access
Semantic Scholar
Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
M. Diril, Xavier Bisteau, M. Kitagawa, Matias J. Caldez +4 more
2016PLoS Genetics40 citations Open access
Semantic Scholar
Less-well known functions of cyclin/CDK complexes.
N. Palmer, P. Kaldis
2020Seminars in Cell and Developmental Biology39 citations Open access
Semantic Scholar
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
Slim Mzoughi, Jia-Yi Fong, David Papadopoli, Cheryl M. Koh +35 more
2020Nature Communications39 citations Open access
Semantic Scholar
CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
C. Windpassinger, J. Piard, C. Bonnard, M. Alfadhel +33 more
2017American Journal of Human Genetics38 citations Open access
Semantic Scholar
Loss of hepatocyte cell division leads to liver inflammation and fibrosis
Matthew R. Dewhurst, Jin Rong Ow, Gözde Zafer, N. V. van Hul +5 more
2020PLoS Genetics37 citations Open access
Semantic Scholar
Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes*
So Yoon Kim, Ji-Hyeon Lee, M. Merrins, O. Gavrilova +4 more
2017Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II
Deepak Adhikari, M. Diril, Kiran Busayavalasa, Sanjiv Risal +8 more
2014Journal of Cell Biology36 citations Open access
Semantic Scholar
The Indispensable Role of Cyclin-Dependent Kinase 1 in Skeletal Development
M. Saito, Mieradili Mulati, S. Zakiah A. Talib, P. Kaldis +3 more
2016Scientific Reports34 citations Open access
Semantic Scholar
Protective functions of ZO-2/Tjp2 expressed in hepatocytes and cholangiocytes against liver injury and cholestasis
Jian-Liang Xu, P. Jaya P. Kausalya, N. V. van Hul, Matias J. Caldez +6 more
2019bioRxiv33 citations Open access
Semantic Scholar
Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress
Senthil Jayapal, C. Q. Wang, Xavier Bisteau, Matias J. Caldez +4 more
2015Haematologica33 citations Open access
Semantic Scholar
Discovery of a chemical probe for PRDM9
A. Allali‐Hassani, M. Szewczyk, D. Ivanochko, S. Organ +26 more
2019Nature Communications31 citations Open access
Semantic Scholar
Liver-derived metabolites as signaling molecules in fatty liver disease
Umur Keles, Jin Rong Ow, K. B. Kuentzel, Na-Zhao Li +1 more
2022Cellular and Molecular Life Sciences30 citations Open access
Semantic Scholar
A novel function for CDK2 activity at meiotic crossover sites
N. Palmer, S. Zakiah A. Talib, Priti Singh, Christine M F Goh +3 more
2020PLoS Biology28 citations Open access
Semantic Scholar
Diverse roles for CDK‐associated activity during spermatogenesis
N. Palmer, S. Zakiah A. Talib, P. Kaldis
2019FEBS Letters28 citations Open access
Semantic Scholar
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype
Joanna Niska-Blakie, Lakshmi Gopinathan, K. Low, Yang Lay Kien +13 more
2019Cellular and Molecular Life Sciences28 citations Open access
Semantic Scholar
Cdk2 catalytic activity is essential for meiotic cell division in vivo
S. Chauhan, M. Diril, J. Lee, Xavier Bisteau +10 more
2016Biochemical Journal28 citations Open access
Semantic Scholar
Regulation of the Embryonic Cell Cycle During Mammalian Preimplantation Development.
N. Palmer, P. Kaldis
2016Current Topics in Developmental Biology27 citations
Semantic Scholar
Cyclin-Dependent Kinase 1 Is Essential for Muscle Regeneration and Overload Muscle Fiber Hypertrophy
Yutaka Kobayashi, Tomoyuki U. Tanaka, Mieradilli Mulati, Hiroki Ochi +5 more
2020Frontiers in Cell and Developmental Biology26 citations Open access
Semantic Scholar
Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death
Quentin Marlier, Florian Jibassia, Sébastien Verteneuil, J. Linden +5 more
2018Cell Death Discovery26 citations Open access
Semantic Scholar
Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis
Shu-Hui Lim, A. Bhinge, Sara Bragado Alonso, I. Aksoy +5 more
2017Molecular and Cellular Biology25 citations Open access
Semantic Scholar
CDK2 kinase activity is a regulator of male germ cell fate
Priti Singh, Ravi K. Patel, N. Palmer, J. Grenier +4 more
2019Development23 citations Open access
Semantic Scholar
Impairing Cohesin Smc1/3 Head Engagement Compensates for the Lack of Eco1 Function.
R. G. Huber, Irina Kulemzina, K. Ang, Alap P. Chavda +9 more
2016Structure23 citations Open access
Semantic Scholar
Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia
Joel H. L. Tan, H. Wollmann, A. V. van Pelt, P. Kaldis +1 more
2020Stem Cell Reports20 citations Open access
Semantic Scholar
Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
Jin Rong Ow, Matias J. Caldez, Gözde Zafer, Juat Chin Foo +9 more
2020eLife19 citations Open access
Semantic Scholar
MetaboKit: a comprehensive data extraction tool for untargeted metabolomics.
P. Narayanaswamy, Guo-Shou Teo, Jin Rong Ow, Adam Lau +3 more
2020Molecular Omics18 citations Open access
Semantic Scholar
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis
Xavier Bisteau, J. Lee, Vinayaka Srinivas, Joanna H. S. Lee +12 more
2020Oncogene16 citations Open access
Semantic Scholar
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
N. Palmer, S. Zakiah A. Talib, Chandrahas Koumar Ratnacaram, D. Low +11 more
2019Journal of Cell Biology15 citations Open access
Semantic Scholar
p27 is regulated independently of Skp2 in the absence of Cdk2
Shuhei Kotoshiba, Lakshmi Gopinathan, Elisabeth Pfeiffenberger, A. Rahim +4 more
2013Biochimica et Biophysica Acta15 citations Open access
Semantic Scholar
Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone
Akira Takahashi, Mieradili Mulati, M. Saito, Hoashi Numata +6 more
2018Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Pairing structural reconstruction with catalytic competence to evaluate the mechanisms of key enzymes in the folate‐mediated one‐carbon pathway
Li-Na Zhao, P. Kaldis
2022The FEBS Journal12 citations Open access
Semantic Scholar
Quo Vadis Cell Growth and Division?
P. Kaldis
2016Front. Cell Dev. Biol.12 citations Open access
Semantic Scholar

Frequent co-authors

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Xavier Bisteau×13
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Xavier Bisteau — researcher profile on SciRah
Matias J. Caldez×12
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Matias J. Caldez — researcher profile on SciRah
V. Coppola×8
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V. Coppola — researcher profile on SciRah
L. Tessarollo×8
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L. Tessarollo — researcher profile on SciRah

S. Zakiah A. Talib

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S. Zakiah A. Talib — researcher profile on SciRah

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N. Palmer — researcher profile on SciRah

Hyungwon Choi×6

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Hyungwon Choi — researcher profile on SciRah

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M. Diril — researcher profile on SciRah

N. V. van Hul×5

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N. V. van Hul — researcher profile on SciRah

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Kui Liu — researcher profile on SciRah

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H. Wollmann — researcher profile on SciRah

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Shu-Hui Lim — researcher profile on SciRah