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X. Yang · SciRah

Researcher profile · Semantic Scholar

X. Yang

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X. Yang — researcher profile on SciRah

h-index: 24
Works: 77
Citations: 2,455

Most-cited papers

MicroRNA Expression Characterizes Oligometastasis(es)
Yves A. Lussier, H. Xing, J. Salama, N. Khodarev +16 more
2011PLoS ONE274 citations Open access
Semantic Scholar
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
M. van den Boogaard, Scott Smemo, Ozanna Burnicka-Turek, D. Arnolds +17 more
2014Journal of Clinical Investigation198 citations Open access
Semantic Scholar
Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.
Ze-Juan Li, Hao Huang, Yuan-Yuan Li, Xi Jiang +26 more
2012Blood182 citations Open access
Semantic Scholar
Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Ze-Juan Li, T. Herold, Chunjiang He, P. Valk +28 more
2013Journal of Clinical Oncology172 citations Open access
Semantic Scholar
Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm
Rangarajan D. Nadadur, M. Broman, B. Boukens, Stefan R. Mazurek +15 more
2016Science Translational Medicine156 citations Open access
Semantic Scholar
Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor Metastasis
Younghee Lee, X. Yang, Yong Huang, H. Fan +10 more
2010PLoS Comput. Biol.155 citations Open access
Semantic Scholar
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects
J. Priest, K. Osoegawa, Nebil Mohammed, Vivek Nanda +24 more
2016PLoS Genetics119 citations Open access
Semantic Scholar
Current and future directions in network biology
M. Zitnik, Michelle M. Li, Aydin Wells, Kimberly Glass +33 more
2023Bioinformatics Advances112 citations Open access
Semantic Scholar
The cardiac TBX5 interactome reveals a chromatin remodeling network essential for cardiac septation
Lauren Waldron, Jeffrey D. Steimle, T. Greco, Nicholas C. Gomez +9 more
2016Developmental Cell90 citations Open access
Semantic Scholar
Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation
Andrew D Hoffmann, X. Yang, Ozanna Burnicka-Turek, J. Bosman +6 more
2014PLoS Genetics83 citations Open access
Semantic Scholar
OrderedList - a bioconductor package for detecting similarity in ordered gene lists
C. Lottaz, X. Yang, S. Scheid, Rainer Spang
2006Bioinform.76 citations
Semantic Scholar
Single Sample Expression-Anchored Mechanisms Predict Survival in Head and Neck Cancer
X. Yang, Kelly Regan, Yong Huang, Qingbei Zhang +5 more
2012PLoS Comput. Biol.74 citations Open access
Semantic Scholar
Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development
Jeffrey D. Steimle, S. Rankin, Christopher E. Slagle, Jenna Bekeny +19 more
2018Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Similarities of Ordered Gene Lists
X. Yang, S. Bentink, S. Scheid, R. Spang
2006J. Bioinform. Comput. Biol.68 citations
Semantic Scholar
Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Ozanna Burnicka-Turek, Jeffrey D. Steimle, Wen-Hui Huang, Lindsay Felker +9 more
2016Human Molecular Genetics53 citations Open access
Semantic Scholar
Bridging Cancer Biology with the Clinic: Relative Expression of a GRHL2-Mediated Gene-Set Pair Predicts Breast Cancer Metastasis
X. Yang, Prabhakaran Vasudevan, Vishwas Parekh, A. Penev +1 more
2013PLoS ONE43 citations Open access
Semantic Scholar
GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns
X. Yang, Jianrong Li, Younghee Lee, Yves A. Lussier
2011Bioinform.43 citations Open access
Semantic Scholar
Research and applications: Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases
Younghee Lee, Hai-Quan Li, Jianrong Li, Ellen Rebman +7 more
2013J. Am. Medical Informatics Assoc.42 citations
Semantic Scholar
Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm
X. Yang, Rangarajan D. Nadadur, Catharina R. E. Hilvering, V. Bianchi +16 more
2017eLife37 citations Open access
Semantic Scholar
Kinase Inhibition-Related Adverse Events Predicted from in vitro Kinome and Clinical Trial Data
X. Yang, Yong Huang, Matthew G. Crowson, Jianrong Li +2 more
2010Journal of Biomedical Informatics37 citations Open access
Semantic Scholar
A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature)
X. Yang, F. Tang, Ji-Su Shin, J. Cunningham
2017Scientific Reports31 citations Open access
Semantic Scholar
Transcriptional Patterning of the Ventricular Cardiac Conduction System
Ozanna Burnicka-Turek, M. Broman, Jeffrey D. Steimle, B. Boukens +10 more
2020Circulation Research29 citations Open access
Semantic Scholar
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
X. Yang, Xiao Sun
2007BMC Bioinformatics29 citations Open access
Semantic Scholar
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
Megan Rowton, Carlos Perez-Cervantes, Suzy S. J. Hur, Jessica Jacobs-Li +21 more
2022Developmental Cell25 citations Open access
Semantic Scholar
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development
S. Rankin, Jeffrey D. Steimle, X. Yang, Ariel B. Rydeen +6 more
2021bioRxiv23 citations Open access
Semantic Scholar
Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors
X. Yang, Andrew S. Goldstein, Yuxi Sun, Zhezhen Wang +3 more
2022Nucleic Acids Research20 citations Open access
Semantic Scholar
Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions
Hai-Quan Li, I. Achour, L. Bastarache, J. Berghout +10 more
2016npj Genomic Medicine20 citations Open access
Semantic Scholar
Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data
Bin Wang, J. Cunningham, X. Yang
2015Bioinform.18 citations Open access
Semantic Scholar
Detecting Common Gene Expression Patterns in Multiple Cancer Outcome Entities
X. Yang, S. Bentink, R. Spang
2005Biomedical microdevices17 citations
Semantic Scholar
A genomic link from heart failure to atrial fibrillation risk: FOG2 modulates a TBX5/GATA4-dependent atrial gene regulatory network
M. Broman, Rangarajan D. Nadadur, Carlos Perez-Cervantes, Ozanna Burnicka-Turek +22 more
2024Circulation16 citations
Semantic Scholar
Characteristics of nucleosome core DNA and their applications in predicting nucleosome positions.
Hong-De Liu, Jiansheng Wu, Jianming Xie, X. Yang +2 more
2008Biophysical Journal16 citations Open access
Semantic Scholar
SVM-Based Approach for Predicting DNA-Binding Residues in Proteins from Amino Acid Sequences
Xin Ma, Jiansheng Wu, Hong-De Liu, X. Yang +2 more
20092009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing13 citations
Semantic Scholar
Cancer Management and Research Dovepress Computational Prognostic Indicators for Breast Cancer
X. Yang, Xin-Lei Ai, J. Cunningham, Xinan +1 more
13 citations
Semantic Scholar
Curation-free biomodules mechanisms in prostate cancer predict recurrent disease
James L. Chen, Alexander W. Hsu, X. Yang, Jianrong Li +4 more
2013BMC Medical Genomics10 citations Open access
Semantic Scholar
Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers
X. Yang, Younghee Lee, Hong Fan, Xiao Sun +1 more
2010Chinese science bulletin = Kexue tongbao10 citations Open access
Semantic Scholar
Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia
X. Yang, Yong Huang, James L. Chen, Jianming Xie +2 more
2009BMC Bioinformatics9 citations Open access
Semantic Scholar
Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma
X. Yang, F. Tang, Ji-Su Shin, J. Cunningham
2017BMC Systems Biology8 citations Open access
Semantic Scholar
Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation
Andrew D Hoffmann, X. Yang, Ozanna Burnicka-Turek, J. Bosman +7 more
2016PLoS Genetics8 citations Open access
Semantic Scholar
Genetic Interactions between Chromosomes 11 and 18 Contribute to Airway Hyperresponsiveness in Mice
C. Ferreira, James L. Chen, Jianrong Li, K. Shimomura +4 more
2012PLoS ONE8 citations Open access
Semantic Scholar
Towards Mechanism Classifiers: Expression-anchored Gene Ontology Signature Predicts Clinical Outcome in Lung Adenocarcinoma Patients
X. Yang, Hai-Quan Li, Kelly Regan, Jianrong Li +3 more
2012American Medical Informatics Association Annual Symposium7 citations
Semantic Scholar
Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles
X. Yang, Bin Wang, J. Cunningham
2015BMC Medical Genomics6 citations Open access
Semantic Scholar
Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq
Xiangyi Sun, Zhezhen Wang, Johnathon M. Hall, Carlos Perez-Cervantes +4 more
2019bioRxiv5 citations Open access
Semantic Scholar
Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia
X. Yang, Mei-Yi Li, Bin Wang, Wanqi Zhu +6 more
2015BMC Bioinformatics5 citations Open access
Semantic Scholar
Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models
X. Yang, Younghee Lee, Yong Huang, James L. Chen +2 more
2010BMC Bioinformatics5 citations Open access
Semantic Scholar
Abstract 3405: MicroRNA expression characterizes oligometastasis(es)
R. Xing, Yves A. Lussier, J. Salama, N. Khodarev +16 more
20124 citations
Semantic Scholar
Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages
Megan Rowton, Carlos Perez-Cervantes, Ariel B. Rydeen, Suzy S. J. Hur +21 more
2020bioRxiv3 citations Open access
Semantic Scholar
Hedgehog signaling controls progenitor differentiation timing during heart development
Megan Rowton, Andrew D Hoffmann, Jeffrey D. Steimle, Suzy S. J. Hur +16 more
20183 citations Open access
Semantic Scholar
Meta-analysis of cancer gene-profiling data.
X. Yang, Xiao Sun
2010Methods in molecular biology3 citations
Semantic Scholar
Similarities of Ordered Gene Lists User’s Guide to the Bioconductor Package OrderedList
S. Scheid, C. Lottaz, X. Yang, R. Spang
20063 citations
Semantic Scholar
Coordinated Tbx3/Tbx5 transcriptional control of the adult ventricular conduction system
Ozanna Burnicka-Turek, K. Trampel, Brigitte Laforest, Michael T Broman +9 more
2025eLife2 citations Open access
Semantic Scholar

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