Jeffrey D. Steimle

Most-cited papers

1. TBX5: A Key Regulator of Heart Development

   Jeffrey D. Steimle, Ivan P. Moskowitz

   2016Current Topics in Developmental Biology178 citations Open access

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2. De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects

   J. Priest, K. Osoegawa, Nebil Mohammed, Vivek Nanda +24 more

   2016PLoS Genetics119 citations Open access

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3. The cardiac TBX5 interactome reveals a chromatin remodeling network essential for cardiac septation

   Lauren Waldron, Jeffrey D. Steimle, T. Greco, Nicholas C. Gomez +9 more

   2016Developmental Cell90 citations Open access

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4. Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation

   Andrew D Hoffmann, X. Yang, Ozanna Burnicka-Turek, J. Bosman +6 more

   2014PLoS Genetics83 citations Open access

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5. Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

   Jeffrey D. Steimle, S. Rankin, Christopher E. Slagle, Jenna Bekeny +19 more

   2018Proceedings of the National Academy of Sciences of the United States of America71 citations Open access

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6. Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

   Ozanna Burnicka-Turek, Jeffrey D. Steimle, Wen-Hui Huang, Lindsay Felker +9 more

   2016Human Molecular Genetics53 citations Open access

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7. Transcriptional Patterning of the Ventricular Cardiac Conduction System

   Ozanna Burnicka-Turek, M. Broman, Jeffrey D. Steimle, B. Boukens +10 more

   2020Circulation Research29 citations Open access

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8. Decoding the PITX2-controlled genetic network in atrial fibrillation

   Jeffrey D. Steimle, Francisco J. Grisanti Canozo, M. Park, Zachary A. Kadow +2 more

   2022JCI Insight26 citations Open access

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9. Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages

   Megan Rowton, Carlos Perez-Cervantes, Suzy S. J. Hur, Jessica Jacobs-Li +21 more

   2022Developmental Cell25 citations Open access

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10. Transcriptional dysregulation underlies both a monogenic arrhythmia syndrome and common modifier of cardiac repolarization

    K. Bersell, Tao Yang, J. Mosley, A. Glazer +30 more

    2022Circulation23 citations

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11. Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

    S. Rankin, Jeffrey D. Steimle, X. Yang, Ariel B. Rydeen +6 more

    2021bioRxiv23 citations Open access

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12. A genomic link from heart failure to atrial fibrillation risk: FOG2 modulates a TBX5/GATA4-dependent atrial gene regulatory network

    M. Broman, Rangarajan D. Nadadur, Carlos Perez-Cervantes, Ozanna Burnicka-Turek +22 more

    2024Circulation16 citations

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13. LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation.

    Idaliz M. Martínez Traverso, Jeffrey D. Steimle, Xiaolei Zhao, Jun Wang +1 more

    2022Development13 citations Open access

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14. The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model

    R. Polk, Péter Gergics, Jeffrey D. Steimle, Hui-Qing Li +3 more

    2015BMC Developmental Biology13 citations Open access

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15. ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

    Jeffrey D. Steimle, Chul Kim, Megan Rowton, Rangarajan D. Nadadur +11 more

    2021bioRxiv12 citations Open access

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16. Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation

    Andrew D Hoffmann, X. Yang, Ozanna Burnicka-Turek, J. Bosman +7 more

    2016PLoS Genetics8 citations Open access

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17. Regrowing the heart, one TREE at a time.

    Jeffrey D. Steimle, James F. Martin

    2023Cell Stem Cell3 citations Open access

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18. Regional and TBX5-Dependent Gene Expression in the Atria: Implications for Pulmonary Vein Development and Atrial Fibrillation

    Jeffrey D. Steimle, Brigitte Laforest, Rangarajan D. Nadadur, M. Broman +1 more

    2020Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension3 citations Open access

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19. Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages

    Megan Rowton, Carlos Perez-Cervantes, Ariel B. Rydeen, Suzy S. J. Hur +21 more

    2020bioRxiv3 citations Open access

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20. Hedgehog signaling controls progenitor differentiation timing during heart development

    Megan Rowton, Andrew D Hoffmann, Jeffrey D. Steimle, Suzy S. J. Hur +16 more

    20183 citations Open access

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21. Sweet and sour story of maternal diabetes and birth defects

    Jeffrey D. Steimle, James F. Martin

    2023Nature Cardiovascular Research1 citations

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22. Abstract MP245: Tet Proteins Regulate Second Heart Field Multipotent Progenitors Differentiating To Myocytes

    Shao-Hai Fang, Jia Li, Jeffrey D. Steimle, Lei Guo +8 more

    2021Circulation Research0 citations

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23. Abstract MP208: A Shared Fog2 / Tbx5-dependent Gene Regulatory Network Identified By Transcription Factor-dependent Non-coding RNA Profiling Modulates Cardiac Rhythm

    Linsin A. Smith, Carlos Perez-Cervantes, M. Broman, Rangarajan D. Nadadur +11 more

    2021Circulation Research0 citations

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24. Abstract 541: A Hedgehog-signaling Dependent Gene Regulatory Network Directly Delays Second Heart Field Differentiation to Prevent Congenital Heart Disease

    Megan Rowton, Ariel B. Rydeen, Perez-Cervantes Carlos, Nikita Deng +16 more

    2020Circulation Research0 citations

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25. Abstract 550: FOG2 Modulates a TBX5-Dependent Gene Regulatory Network for Cardiac Rhythm Homeostasis

    Sonja Lazarevic, M. Broman, Rangarajan D. Nadadur, Jeffrey D. Steimle +10 more

    2020Circulation Research0 citations

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26. Enhancing Pace: Identifying and Validating the Cis-Regulatory Landscape of the Sinoatrial Node

    Jeffrey D. Steimle, Chang-Ru Tsai, James F. Martin

    2020Circulation Research0 citations

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27. Abstract MP115: Transcriptional Patterning of the Ventricular Cardiac Conduction System

    Ozanna Burnicka-Turek, M. Broman, Jeffrey D. Steimle, B. Boukens +8 more

    20200 citations

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28. Abstract 10344: Transcriptional Patterning of the Cardiac Conduction System Prevents Arrhythmias

    Ozanna Burnicka-Turek, M. Broman, Jeffrey D. Steimle, B. Boukens +10 more

    2018Circulation0 citations

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29. Abstract 16157: A TBX5 Driven Gene Regulatory Network Prevents Atrial Fibrillation

    Rangarajan D. Nadadur, M. Broman, B. Boukens, Stefan R. Mazurek +7 more

    20150 citations

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