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Brian J. Geist · SciRah

Researcher profile · Semantic Scholar

Brian J. Geist

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Brian J. Geist — researcher profile on SciRah

h-index: 8
Works: 20
Citations: 250

Most-cited papers

Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
S. Edavettal, P. Cejudo-Martı́n, B. Dasgupta, Danlin Yang +20 more
2022i Medicina71 citations Open access
Semantic Scholar
Characterization of critical reagents in ligand-binding assays: enabling robust bioanalytical methods and lifecycle management.
Brian J. Geist, Adrienne Clements Egan, Tong-Yuan Yang, Yu-Xin Dong +1 more
2013Bioanalysis54 citations
Semantic Scholar
Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
Xi Chen, Xi-Ling Jiang, Rajitha Doddareddy, Brian J. Geist +4 more
2018Journal of Pharmacology and Experimental Therapeutics26 citations Open access
Semantic Scholar
Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A
Song-Mao Zheng, F. Shen, B. Jones, D. Fink +7 more
2020mAbs19 citations Open access
Semantic Scholar
Discovery and characterization of single-domain antibodies for polymeric Ig receptor-mediated mucosal delivery of biologics
B. V. Maruthachalam, A. Zwolak, Xiefan Lin-Schmidt, Edward Keough +5 more
2020mAbs14 citations Open access
Semantic Scholar
Matrix effect in ligand-binding assay: the importance of evaluating emerging technologies.
Rebecca M. Crisino, Linlin Luo, Brian J. Geist, J. Zoghbi +1 more
2014Bioanalysis13 citations
Semantic Scholar
A novel approach for the simultaneous quantification of a therapeutic monoclonal antibody in serum produced from two distinct host cell lines
Brian J. Geist, Darryl L. Davis, T. McIntosh, Tong-Yuan Yang +4 more
2013mAbs9 citations Open access
Semantic Scholar
Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment
Ian White, Ninkka Tamot, Rajitha Doddareddy, J. Ho +9 more
2021mAbs8 citations Open access
Semantic Scholar
A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model
Song-Mao Zheng, D. Polidori, Yuanping Wang, Brian J. Geist +5 more
2022bioRxiv7 citations Open access
Semantic Scholar
A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model
Song-Mao Zheng, Jin Niu, Brian J. Geist, D. Fink +3 more
2020mAbs7 citations Open access
Semantic Scholar
Abstract ND07: JNJ-78306358: A first-in-class bispecific T cell redirecting HLA-G antibody
N. Obermajer, A. Zwolak, Kelly van de Ven, Shana Versmissen +31 more
2022Cancer Research6 citations
Semantic Scholar
Application of multiplexed pharmacokinetic immunoassay to quantify in vivo drug forms and coadministered biologics.
Nicole Woodbury, E. Bald, Brian J. Geist, Tong-Yuan Yang
2019Bioanalysis5 citations Open access
Semantic Scholar
Translational PK/PD and model‐informed development of JNJ‐67842125, a Fab reversal agent for JNJ‐64179375, a long‐acting thrombin inhibitor
Vivaswath S. Ayyar, Pharavee Jaiprasart, Brian J. Geist, Zheng Huang Devine +5 more
2021British Journal of Pharmacology4 citations Open access
Semantic Scholar
Monitoring Quality of Critical Reagents Used in Ligand Binding Assays with Liquid Chromatography Mass Spectrometry (LC‐MS)
Brian J. Geist, A. Clements-Egan, Tong-Yuan Yang
20173 citations
Semantic Scholar
A Novel Approach to Evaluate the Pharmacokinetic Biocomparability of a Monoclonal Antibody Derived from Two Different Cell Lines Using Simultaneous Crossover Design
Chao Han, T. McIntosh, Brian J. Geist, T. Jiao +6 more
2013AAPS Journal3 citations Open access
Semantic Scholar
In vitro and in vivo characterization of wild type BMP9 and a non-osteogenic variant in models of pulmonary arterial hypertension
Tobias G. Schips, Karl W. Kavalkovich, Lai Yung, S. Ibrahim +14 more
2025PLoS ONE1 citations Open access
Semantic Scholar
Therapeutic antibody development—Remington chapter
Brian J. Geist, Song-Mao Zheng, Yan Xu
20211 citations
Semantic Scholar
"…it is essential to continuously identify and evaluate emerging technologies, or look to novel approaches of existing technologies that can alleviate interference problems."
Rebecca M. Crisino, Linlin Luo, Brian J. Geist, J. Zoghbi +1 more
20140 citations
Semantic Scholar
A Novel Approach to Evaluate the Pharmacokinetic Biocomparability of a Monoclonal Antibody Derived from Two Different Cell Lines Using Simultaneous Crossover Design
Chao Han, T. McIntosh, Brian J. Geist, T. Jiao +6 more
2013AAPS Journal0 citations Open access
Semantic Scholar
Conference report: Bioanalysis highlights from the 2012 American Association of Pharmaceutical Scientists National Biotechnology Conference.
Rebecca M. Crisino, Brian J. Geist, Jian Li
2012Bioanalysis0 citations
Semantic Scholar

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