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N. Obermajer · SciRah

Researcher profile · Semantic Scholar

N. Obermajer

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N. Obermajer — researcher profile on SciRah

h-index: 37
Works: 95
Citations: 5,038

Most-cited papers

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells.
N. Obermajer, Ravikumar Muthuswamy, Jamie L. Lesnock, R. Edwards +1 more
2011Blood486 citations Open access
Semantic Scholar
Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody.
P. Kocbek, N. Obermajer, M. Cegnar, J. Kos +1 more
2007Journal of Controlled Release446 citations
Semantic Scholar
PGE2-Induced CXCL12 Production and CXCR4 Expression Controls the Accumulation of Human MDSCs in Ovarian Cancer Environment
N. Obermajer, Ravikumar Muthuswamy, K. Odunsi, R. Edwards +1 more
2011Cancer Research437 citations Open access
Semantic Scholar
C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity
U. Švajger, M. Anderluh, M. Jeras, N. Obermajer
2010Cellular Signalling246 citations Open access
Semantic Scholar
Interleukin-23 dependent IL-17 drives Th1 responses following Mycobacterium bovis BCG vaccination
R. Gopal, Yin-Yao Lin, N. Obermajer, Samantha R. Slight +4 more
2011European Journal of Immunology182 citations Open access
Semantic Scholar
Potential hepatoprotective effects of fullerenol C60(OH)24 in doxorubicin-induced hepatotoxicity in rats with mammary carcinomas.
R. Injac, M. Perše, N. Obermajer, V. Djordjevic-Milic +4 more
2008Biomaterials172 citations
Semantic Scholar
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
Stephanie Downs-Canner, Sara E. Berkey, Greg M. Delgoffe, R. Edwards +4 more
2017Nature Communications157 citations Open access
Semantic Scholar
Quantification of live and dead probiotic bacteria in lyophilised product by real-time PCR and by flow cytometry
Mateja Kramer, N. Obermajer, B. Bogovič-Matijašić, I. Rogelj +1 more
2009Applied Microbiology and Biotechnology157 citations
Semantic Scholar
Conversion of Th17 into IL-17Aneg Regulatory T Cells: A Novel Mechanism in Prolonged Allograft Survival Promoted by Mesenchymal Stem Cell–Supported Minimized Immunosuppressive Therapy
N. Obermajer, F. Popp, Y. Soeder, J. Haarer +3 more
2014Journal of Immunology139 citations Open access
Semantic Scholar
Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells.
J. Rodríguez-Ubreva, F. Català-Moll, N. Obermajer, D. Álvarez-Errico +8 more
2017Cell Reports125 citations Open access
Semantic Scholar
PGE2-Driven Induction and Maintenance of Cancer-Associated Myeloid-Derived Suppressor Cells
N. Obermajer, Jeffrey L. Wong, R. Edwards, K. Odunsi +2 more
2012Immunological Investigations117 citations
Semantic Scholar
Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling
N. Obermajer, Jeffrey L. Wong, R. Edwards, Kong Chen +6 more
2013Journal of Experimental Medicine115 citations Open access
Semantic Scholar
PURIFICATION, CHARACTERIZATION AND CLONING OF A RICIN B-LIKE LECTIN FROM MUSHROOM Clitocybe nebularis WITH ANTIPROLIFERATIVE ACTIVITY AGAINST HUMAN LEUKEMIC T CELLS
J. Pohleven, N. Obermajer, J. Sabotič, S. Anžlovar +5 more
2008Biochimica et Biophysica Acta108 citations Open access
Semantic Scholar
Generation of myeloid-derived suppressor cells using prostaglandin E2
N. Obermajer, P. Kalinski
2012Transplantation Research106 citations Open access
Semantic Scholar
Human Tolerogenic Dendritic Cells Regulate Immune Responses through Lactate Synthesis.
Eros Marín, L. Bouchet-Delbos, Ophélie Renoult, C. Louvet +21 more
2019Cell Metabolism102 citations Open access
Semantic Scholar
γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways.
A. Hafner, N. Obermajer, J. Kos
2012Biochemical Journal100 citations
Semantic Scholar
Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation
U. Švajger, N. Obermajer, M. Jeras
2010Immunology94 citations Open access
Semantic Scholar
Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds
B. Mirković, M. Renko, Samo Turk, Izidor Sosič +5 more
2011ChemMedChem85 citations Open access
Semantic Scholar
The role of cathepsin X in cell signaling
J. Kos, Z. Jevnikar, N. Obermajer
2009Cell Adhesion & Migration83 citations Open access
Semantic Scholar
Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells.
N. Obermajer, A. Premzl, Tina Zavašnik Bergant, B. Turk +1 more
2006Experimental Cell Research78 citations
Semantic Scholar
Neuroprotective role of γ‐enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X
A. Hafner, G. Glavan, N. Obermajer, M. Živin +2 more
2013Aging Cell77 citations Open access
Semantic Scholar
DHRS9 Is a Stable Marker of Human Regulatory Macrophages
P. Riquelme, G. Amodio, C. Macedo, A. Moreau +12 more
2017Transplantation74 citations Open access
Semantic Scholar
The role of cathepsin X in the migration and invasiveness of T lymphocytes
Z. Jevnikar, N. Obermajer, M. Bogyo, J. Kos
2008Journal of Cell Science72 citations
Semantic Scholar
Role of Cysteine Cathepsins in Matrix Degradation and Cell Signalling
N. Obermajer, Z. Jevnikar, B. Doljak, J. Kos
2008Connective Tissue Research67 citations
Semantic Scholar
Cysteine protease cathepsin X modulates immune response via activation of β2 integrins
N. Obermajer, U. Repnik, Z. Jevnikar, B. Turk +2 more
2008Immunology63 citations Open access
Semantic Scholar
Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells.
N. Obermajer, B. Doljak, P. Jamnik, U. P. Fonović +1 more
2009International Journal of Biochemistry and Cell Biology60 citations
Semantic Scholar
Synergistic COX2 induction by IFNγ and TNFα self-limits type-1 immunity in the human tumor microenvironment
Jeffrey L. Wong, N. Obermajer, K. Odunsi, R. Edwards +1 more
2016Cancer immunology research58 citations Open access
Semantic Scholar
Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X
N. Obermajer, U. Švajger, Mathew Bogyo, M. Jeras +1 more
2008Journal of Leukocyte Biology58 citations Open access
Semantic Scholar
Key role of the positive feedback between PGE2 and COX2 in the biology of myeloid-derived suppressor cells
N. Obermajer, P. Kalinski
2012Oncoimmunology50 citations Open access
Semantic Scholar
Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer.
J. Decock, N. Obermajer, S. Vozelj, Wouter Hendrickx +2 more
2008International Journal of Biological Markers50 citations
Semantic Scholar
Oncolytic Virus Promotes Tumor-Reactive Infiltrating Lymphocytes for Adoptive Cell Therapy
M. Feist, Zhi Zhu, En-Yong Dai, Cong-Rong Ma +10 more
2020Cancer Gene Therapy49 citations Open access
Semantic Scholar
Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells.
Špela Magister, N. Obermajer, B. Mirković, U. Švajger +6 more
2012European Journal of Cell Biology48 citations
Semantic Scholar
Engineered Lactic Acid Bacterium Lactococcus lactis Capable of Binding Antibodies and Tumor Necrosis Factor Alpha
M. Ravnikar, B. S̆trukelj, N. Obermajer, M. Lunder +1 more
2010Applied and Environmental Microbiology42 citations Open access
Semantic Scholar
Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer
Stephanie Downs-Canner, D. Magge, Roshni Ravindranathan, M. E. O'Malley +5 more
2015Annals of Surgical Oncology41 citations Open access
Semantic Scholar
Cysteine cathepsins: regulators of antitumour immune response
N. Obermajer, B. Doljak, J. Kos
2006Expert Opinion on Biological Therapy41 citations
Semantic Scholar
Gamma-1-Syntrophin Mediates Trafficking of Gamma-Enolase towards the Plasma Membrane and Enhances Its Neurotrophic Activity
A. Hafner, N. Obermajer, J. Kos
2011Neurosignals39 citations
Semantic Scholar
Promoting the accumulation of tumor-specific T cells in tumor tissues by dendritic cell vaccines and chemokine-modulating agents
N. Obermajer, J. Urban, E. Wieckowski, Ravikumar Muthuswamy +3 more
2018Nature Protocols37 citations
Semantic Scholar
Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness
N. Obermajer, B. Doljak, J. Kos
2009Molecular Cancer36 citations Open access
Semantic Scholar
Novel Findings in Drug-Induced Dendritic Cell Tolerogenicity
U. Švajger, N. Obermajer, M. Jeras
2010International Reviews of Immunology33 citations
Semantic Scholar
IFN‐γ‐rich environment programs dendritic cells toward silencing of cytotoxic immune responses
U. Švajger, N. Obermajer, M. Jeras
2014Journal of Leukocyte Biology31 citations
Semantic Scholar
Design, synthesis and activity evaluation of mannose-based DC-SIGN antagonists
N. Obermajer, S. Sattin, C. Colombo, M. Bruno +3 more
2010Molecular diversity31 citations Open access
Semantic Scholar
Cathepsin X cleavage of the β2 integrin regulates talin‐binding and LFA‐1 affinity in T cells
Z. Jevnikar, N. Obermajer, B. Doljak, Samo Turk +5 more
2011Journal of Leukocyte Biology28 citations Open access
Semantic Scholar
Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.
T. Tomašič, David Hajšek, U. Švajger, J. Luzar +4 more
2014European journal of medicinal chemistry27 citations Open access
Semantic Scholar
DC‐SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function
U. Švajger, N. Obermajer, M. Anderluh, J. Kos +1 more
2011Journal of Leukocyte Biology25 citations Open access
Semantic Scholar
Inactivation of harmful tumour-associated proteolysis by nanoparticulate system.
J. Kos, N. Obermajer, B. Doljak, P. Kocbek +1 more
2009International journal of pharmaceutics25 citations
Semantic Scholar
Positive feedback between PGE 2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
N. Obermajer, Ravikumar Muthuswamy, Jamie L. Lesnock, Robert P. Edwards +1 more
201124 citations
Semantic Scholar
Cathepsin X cleaves the β2 cytoplasmic tail of LFA‐1 inducing the intermediate affinity form of LFA‐1 and α‐actinin‐1 binding
Z. Jevnikar, N. Obermajer, Urša Pečar-Fonović, A. Karaoglanovic-Carmona +1 more
2009European Journal of Immunology24 citations Open access
Semantic Scholar
Cathepsin B, Cathepsin H, Cathepsin X and Cystatin C in Sera of Patients with Early-Stage and Inflammatory Breast Cancer
J. Decock, N. Obermajer, S. Vozelj, Wouter Hendrickx +2 more
200823 citations Open access
Semantic Scholar
Immunonanoparticles − an effective tool to impair harmful proteolysis in invasive breast tumor cells
N. Obermajer, P. Kocbek, U. Repnik, A. Kužnik +3 more
2007The FEBS Journal23 citations
Semantic Scholar
Rationale and prospects of mesenchymal stem cell therapy for liver transplantation
N. Obermajer, F. Popp, Christian Johnson, V. Benseler +1 more
2014Current Opinion in Organ Transplantation21 citations
Semantic Scholar

Frequent co-authors

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J. Kos×23
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J. Kos — researcher profile on SciRah
P. Kalinski×10
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P. Kalinski — researcher profile on SciRah
U. Švajger×10
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U. Švajger — researcher profile on SciRah
R. Edwards×7
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Z. Jevnikar — researcher profile on SciRah

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M. Jeras — researcher profile on SciRah

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B. Doljak — researcher profile on SciRah

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K. Odunsi — researcher profile on SciRah

Ravikumar Muthuswamy×4

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M. Anderluh — researcher profile on SciRah

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D. Bartlett — researcher profile on SciRah

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P. Kocbek — researcher profile on SciRah