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J. Hartwig · SciRah

Researcher profile · Semantic Scholar

J. Hartwig

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J. Hartwig — researcher profile on SciRah

h-index: 84
Works: 215
Citations: 26K

Most-cited papers

Extracellular DNA traps promote thrombosis
T. Fuchs, A. Brill, D. Duerschmied, Daphne Schatzberg +6 more
2010Proceedings of the National Academy of Sciences of the United States of America2,500 citations Open access
Semantic Scholar
Paneth cells as a site of origin for intestinal inflammation
Timon E. Adolph, Michal Tomczak, L. Niederreiter, Hyun-Jeong Ko +22 more
2013Nature703 citations Open access
Semantic Scholar
Liquids and Structural Glasses Special Feature: An active biopolymer network controlled by molecular motors
G. Koenderink, Z. Dogic, Fumihiko Nakamura, P. Bendix +4 more
2009416 citations
Semantic Scholar
Filamins in cell signaling, transcription and organ development.
Alex-Xianghua Zhou, J. Hartwig, Levent M. Akyürek
2010Trends in Cell Biology326 citations
Semantic Scholar
The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling
R. Grozovsky, A. Begonja, Kaifeng Liu, G. Visner +3 more
2014Nature Medicine314 citations Open access
Semantic Scholar
Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice.
G. M. Thomas, Carla Carbó, B. Curtis, K. Martinod +8 more
2011Blood314 citations Open access
Semantic Scholar
Cytoskeletal mechanics of proplatelet maturation and platelet release
Jonathan N. Thon, A. Montalvo, S. Patel-Hett, Matthew T. Devine +6 more
2010Journal of Cell Biology293 citations Open access
Semantic Scholar
Structural basis of filamin A functions
Fumihiko Nakamura, Teresia M. Osborn, C. A. Hartemink, J. Hartwig +1 more
2007Journal of Cell Biology290 citations Open access
Semantic Scholar
The filamins
Fumihiko Nakamura, T. Stossel, J. Hartwig
2011Cell Adhesion & Migration285 citations Open access
Semantic Scholar
Protein 4.1R-dependent multiprotein complex: New insights into the structural organization of the red blood cell membrane
Marcela Salomao, Xi-Hui Zhang, Yang Yang, Soohee Lee +4 more
2008Proceedings of the National Academy of Sciences of the United States of America251 citations Open access
Semantic Scholar
Direct dynamin–actin interactions regulate the actin cytoskeleton
C. Gu, S. Yaddanapudi, Astrid Weins, Teresia M. Osborn +4 more
2010EMBO Journal239 citations Open access
Semantic Scholar
Dual roles for hepatic lectin receptors in the clearance of chilled platelets
Viktoria Rumjantseva, P. Grewal, H. Wandall, E. Josefsson +5 more
2009Nature Medicine221 citations Open access
Semantic Scholar
Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.
Anne Louise Tølbøll Sørensen, Viktoria Rumjantseva, Sara Nayeb-Hashemi, H. Clausen +3 more
2009Blood209 citations Open access
Semantic Scholar
Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.
A. J. Gerard Jansen, E. Josefsson, Viktoria Rumjantseva, Qiyong Peter Liu +8 more
2012Blood198 citations Open access
Semantic Scholar
CLEC-2 activates Syk through dimerisation
C. Hughes, A. Pollitt, Jun Mori, J. Eble +5 more
2010Blood174 citations Open access
Semantic Scholar
Differential Remodeling of Actin Cytoskeleton Architecture by Profilin Isoforms Leads to Distinct Effects on Cell Migration and Invasion
G. Mouneimne, Scott D. Hansen, L. Selfors, Lara J. Petrak +8 more
2012Cancer Cell159 citations Open access
Semantic Scholar
Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity
Astrid Weins, Johannes S. Schlondorff, Fumihiko Nakamura, B. Denker +3 more
2007Proceedings of the National Academy of Sciences of the United States of America157 citations Open access
Semantic Scholar
Microtubule and cortical forces determine platelet size during vascular platelet production
Jonathan N. Thon, H. Macleod, A. Begonja, Jie Zhu +4 more
2012Nature Communications155 citations Open access
Semantic Scholar
Differential stimulation of monocytic cells results in distinct populations of microparticles
M. Bernimoulin, E. Waters, Martina Foy, Brian M. Steele +8 more
2009Journal of Thrombosis and Haemostasis155 citations Open access
Semantic Scholar
Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.
S. Patel-Hett, Jennifer L. Richardson, H. Schulze, K. Drabek +7 more
2008Blood149 citations Open access
Semantic Scholar
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function
H. Falet, A. Pollitt, A. Begonja, Sarah E. Weber +4 more
2010Journal of Experimental Medicine130 citations Open access
Semantic Scholar
GLUT4 Vesicle Recruitment and Fusion Are Differentially Regulated by Rac, AS160, and Rab8A in Muscle Cells*
V. Randhawa, S. Ishikura, Ilana Talior-Volodarsky, A. W. Cheng +3 more
2008Journal of Biological Chemistry120 citations Open access
Semantic Scholar
B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.
M. Recher, S. Burns, M. A. de la Fuente, Stefano Volpi +31 more
2012Blood118 citations Open access
Semantic Scholar
Mechanics of proplatelet elaboration
J. Italiano, S. Patel-Hett, J. Hartwig
2007Journal of Thrombosis and Haemostasis118 citations Open access
Semantic Scholar
Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein.
M. Bender, Jonathan N. Thon, Allen J. Ehrlicher, Stephen K. Wu +5 more
2015Blood116 citations Open access
Semantic Scholar
FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly.
Antonija Jurak Begonja, K. Hoffmeister, J. Hartwig, H. Falet
2011Blood111 citations Open access
Semantic Scholar
A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.
E. Janssen, Mira Tohmé, M. Hedayat, Marion Leick +15 more
2016Journal of Clinical Investigation103 citations Open access
Semantic Scholar
Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex
Natalie S. Poulter, A. Pollitt, A. Davies, Dessislava Malinova +9 more
2015Nature Communications103 citations Open access
Semantic Scholar
The origin and function of platelet glycosyltransferases.
H. Wandall, Viktoria Rumjantseva, Anne Louise Tølbøll Sørensen, S. Patel-Hett +6 more
2012Blood101 citations Open access
Semantic Scholar
ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing.
M. Bender, A. Eckly, J. Hartwig, M. Elvers +9 more
2010Blood94 citations
Semantic Scholar
Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
E. Battinelli, J. Hartwig, J. Italiano
2007Current opinion in hematology94 citations
Semantic Scholar
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.
S. Patel-Hett, Hong-Bei Wang, A. Begonja, Jonathan N. Thon +6 more
2011Blood88 citations Open access
Semantic Scholar
Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott–Aldrich syndrome-like platelet defect
M. Bender, Simon Stritt, P. Nurden, J. V. van Eeuwijk +13 more
2014Nature Communications84 citations Open access
Semantic Scholar
Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton.
J. Moyer, Roberta B. Nowak, Nancy E. Kim, Sandra Larkin +4 more
2010Blood84 citations Open access
Semantic Scholar
Galactosylation does not prevent the rapid clearance of long-term, 4°C-stored platelets
M. Lozano, H. Wandall, K. Hoffmeister, Anne Louise Tølbøll Sørensen +4 more
200882 citations Open access
Semantic Scholar
Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.
Yanfeng Wang, R. Litvinov, Xin-Sheng Chen, Tami L. Bach +10 more
2008Journal of Clinical Investigation82 citations Open access
Semantic Scholar
RefilinB (FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape
Olivia Gay, Benoît Gilquin, Fumihiko Nakamura, Z. Jenkins +7 more
2011Proceedings of the National Academy of Sciences of the United States of America81 citations Open access
Semantic Scholar
SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.
Jianwu Bai, J. Hartwig, N. Perrimon
2007Developmental Cell80 citations Open access
Semantic Scholar
Molecular Basis of Filamin A-FilGAP Interaction and Its Impairment in Congenital Disorders Associated with Filamin A Mutations
Fumihiko Nakamura, Outi K. Heikkinen, O. Pentikäinen, Teresia M. Osborn +8 more
2009PLoS ONE75 citations Open access
Semantic Scholar
FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.
A. Begonja, F. Pluthero, Worawit Suphamungmee, Silvia Giannini +10 more
2015Blood61 citations Open access
Semantic Scholar
Loss of PIP5KIβ demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation
Yanfeng Wang, Xin-Sheng Chen, L. Lian, Tang K. Tang +6 more
2008Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread
Ellen A Bishai, Gurjit S. Sidhu, Wei Li, Jess Dhillon +4 more
2012Cellular Microbiology48 citations Open access
Semantic Scholar
Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott–Aldrich syndrome-like platelet defect
M. Bender, Simon Stritt, P. Nurden, J. V. van Eeuwijk +13 more
2014Nature Communications47 citations Open access
Semantic Scholar
Galactosylation does not prevent the rapid clearance of long-term, 4 degrees C-stored platelets.
H. Wandall, K. Hoffmeister, Anne Louise Tølbøll Sørensen, Viktoria Rumjantseva +3 more
2008Blood45 citations
Semantic Scholar
Documentation and Localization of Force-mediated Filamin A Domain Perturbations in Moving Cells
Fumihiko Nakamura, Mia Song, J. Hartwig, T. Stossel
2014Nature Communications44 citations Open access
Semantic Scholar
Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.
K. Machlus, Stephen K. Wu, D. Stumpo, T. Soussou +9 more
2016Blood40 citations Open access
Semantic Scholar
Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion
J. Rullo, H. Becker, S. Hyduk, J. Wong +6 more
2012Journal of Cell Biology37 citations Open access
Semantic Scholar
Cystic Fibrosis Transmembrane Conductance Regulator Interacts with Multiple Immunoglobulin Domains of Filamin A*
M. Playford, Elisa M. Nurminen, O. Pentikäinen, S. L. Milgram +3 more
2010Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia.
Yunzhe Lu, Toshihiko Hanada, Y. Fujiwara, Jennifer O. Nwankwo +5 more
2016Blood33 citations Open access
Semantic Scholar
WIP is critical for T cell responsiveness to IL-2
S. Le Bras, M. Massaad, Suresh Koduru, L. Kumar +3 more
2009Proceedings of the National Academy of Sciences of the United States of America28 citations Open access
Semantic Scholar

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K. Hoffmeister×11
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K. Hoffmeister — researcher profile on SciRah
Fumihiko Nakamura×9
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Fumihiko Nakamura — researcher profile on SciRah
H. Falet×9
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H. Falet — researcher profile on SciRah
J. Italiano×9
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J. Italiano — researcher profile on SciRah

×7

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T. Stossel — researcher profile on SciRah

Viktoria Rumjantseva×6

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Viktoria Rumjantseva — researcher profile on SciRah

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D. Wagner — researcher profile on SciRah

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A. Begonja — researcher profile on SciRah

S. Patel-Hett×5

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S. Patel-Hett — researcher profile on SciRah

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H. Wandall — researcher profile on SciRah

Anne Louise Tølbøll Sørensen×5

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Anne Louise Tølbøll Sørensen — researcher profile on SciRah

Jonathan N. Thon×4

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Jonathan N. Thon — researcher profile on SciRah