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K. Sourris · SciRah

Researcher profile · Semantic Scholar

K. Sourris

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K. Sourris — researcher profile on SciRah

h-index: 26
Works: 72
Citations: 2,740

Most-cited papers

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.
M. Coughlan, D. Thorburn, S. Penfold, A. Laskowski +10 more
2009Journal of the American Society of Nephrology467 citations Open access
Semantic Scholar
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
V. Thallas-Bonke, S. Thorpe, M. Coughlan, K. Fukami +6 more
2008Diabetes358 citations Open access
Semantic Scholar
Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes.
M. Coughlan, Tuong-Vi Nguyen, S. Penfold, G. Higgins +9 more
2016Clinical science158 citations
Semantic Scholar
Processed foods drive intestinal barrier permeability and microvascular diseases
M. Snelson, Sih-Min Tan, R. E. Clarke, Cassandra de Pasquale +18 more
2021Science Advances131 citations Open access
Semantic Scholar
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.
A. Tan, K. Sourris, Brooke E. Harcourt, V. Thallas-Bonke +8 more
2010AJP - Renal Physiology131 citations
Semantic Scholar
Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products-induced inflammation.
K. Sourris, Yi Ding, S. Maxwell, A. Al-sharea +20 more
2023Kidney International126 citations Open access
Semantic Scholar
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes.
K. Sourris, Brooke E. Harcourt, Peter H. Tang, A. L. Morley +7 more
2012Free Radical Biology & Medicine126 citations
Semantic Scholar
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial.
B. de Courten, Maximilian P. J. de Courten, G. Soldatos, Sonia L. Dougherty +10 more
2016American Journal of Clinical Nutrition123 citations Open access
Semantic Scholar
Targeted reduction of advanced glycation improves renal function in obesity.
Brooke E. Harcourt, K. Sourris, M. Coughlan, K. Walker +13 more
2011Kidney International115 citations Open access
Semantic Scholar
The Receptor For Advanced Glycation End-Products (RAGE) exerts renoprotective effects via the AT-2 receptor in Diabetic Nephropathy
K. Sourris, A. L. Morley, A. Koitka, P. Samuel +11 more
2010Diabetologia83 citations Open access
Semantic Scholar
Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy.
S. Penfold, M. Coughlan, Sheila K. Patel, P. Srivastava +9 more
2010Kidney International79 citations Open access
Semantic Scholar
Interactions Between Advanced Glycation End-Products (AGE) and their Receptors in the Development and Progression of Diabetic Nephropathy – are these Receptors Valid Therapeutic Targets
K. Sourris, J. Forbes
200968 citations
Semantic Scholar
Interactions between advanced glycation end-products (AGE) and their receptors in the development and progression of diabetic nephropathy - are these receptors valid therapeutic targets.
K. Sourris, J. Forbes
2009Current Drug Targets61 citations
Semantic Scholar
Deficiency in Mitochondrial Complex I Activity Due to Ndufs6 Gene Trap Insertion Induces Renal Disease
J. Forbes, Bi-Xia Ke, Tuong-Vi Nguyen, D. Henstridge +7 more
2013Antioxidants and Redox Signaling60 citations
Semantic Scholar
Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis
M. Coughlan, G. Higgins, Tuong-Vi Nguyen, S. Penfold +29 more
2016Diabetes52 citations Open access
Semantic Scholar
Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
K. Sourris, A. Watson, K. Jandeleit-Dahm
2020Handbook of Experimental Pharmacology48 citations
Semantic Scholar
Effect of vitamin D supplementation on inflammation and nuclear factor kappa-B activity in overweight/obese adults: a randomized placebo-controlled trial
Aya Mousa, N. Naderpoor, Josphin Johnson, K. Sourris +5 more
2017Scientific Reports48 citations Open access
Semantic Scholar
Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes
J. M. Forbes, J. Söderlund, F. Yap, M. Knip +14 more
2011Diabetologia47 citations Open access
Semantic Scholar
Advanced Glycation Urinary Protein-Bound Biomarkers and Severity of Diabetic Nephropathy in Man
M. Coughlan, Sheila K. Patel, G. Jerums, S. Penfold +8 more
2011American Journal of Nephrology40 citations Open access
Semantic Scholar
c-Jun NH2-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals
K. Sourris, J. Lyons, M. de Courten, Sonia L. Dougherty +7 more
2009Diabetes39 citations Open access
Semantic Scholar
Angiotensin II subtype 2 receptor blockade and deficiency attenuate the development of atherosclerosis in an apolipoprotein E-deficient mouse model of diabetes
A. Koitka, Zemin M Cao, P. Koh, A. Watson +8 more
2010Diabetologia38 citations Open access
Semantic Scholar
Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects
J. Forbes, K. Sourris, M. de Courten, Sonia L. Dougherty +10 more
2013Amino Acids37 citations
Semantic Scholar
A New Perspective on Therapeutic Inhibition of Advanced Glycation in Diabetic Microvascular Complications: Common Downstream Endpoints Achieved Through Disparate Therapeutic Approaches?
K. Sourris, Brooke E. Harcourt, J. Forbes
2009American Journal of Nephrology34 citations Open access
Semantic Scholar
Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes
G. Tesch, K. Sourris, S. Summers, D. McCarthy +12 more
2014Diabetologia32 citations Open access
Semantic Scholar
An Engineered Nanosugar Enables Rapid and Sustained Glucose-Responsive Insulin Delivery in Diabetic Mice.
Rong Xu, S. K. Bhangu, K. Sourris, D. Vanni +14 more
2023Advances in Materials31 citations Open access
Semantic Scholar
Increased liver AGEs induce hepatic injury mediated through an OST48 pathway
Ao-Wen Zhuang, F. Yap, C. Bruce, C. Leung +13 more
2017Scientific Reports27 citations Open access
Semantic Scholar
Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure
K. Sourris, J. Lyons, Sonia L. Dougherty, V. Chand +8 more
2014Clinical Chemistry and Laboratory Medicine24 citations
Semantic Scholar
RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis
Shinji Hagiwara, K. Sourris, M. Ziemann, Tieqiao Wu +14 more
2018Diabetes22 citations Open access
Semantic Scholar
Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy
K. Sourris, Brooke E. Harcourt, S. Penfold, F. Yap +6 more
2011International Journal of Experimental Diabetes Research20 citations Open access
Semantic Scholar
Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events in Diabetic Nephropathy?
K. Sourris, Henry Yao, G. Jerums, M. Cooper +2 more
2016Current Drug Targets18 citations
Semantic Scholar
The role of activator protein-1 (AP-1) complex in diabetes associated atherosclerosis: Insights from single cell RNA sequencing.
Abdul Waheed Khan, M. Aziz, K. Sourris, Man Ks Lee +10 more
2024Diabetes17 citations Open access
Semantic Scholar
Therapeutic Interruption of Advanced Glycation in Diabetic Nephropathy
K. Sourris, J. Forbes, M. E. Cooper
2008Annals of the New York Academy of Sciences17 citations
Semantic Scholar
Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis
Florence Ho, A. Watson, Mahmoud H. Elbatreek, Pamela W. M. Kleikers +6 more
2022Scientific Reports13 citations Open access
Semantic Scholar
miR-214 and its primary transcript Dnm3os regulate fibrosis and inflammation through RAGE signalling in diabetic kidney disease.
Shinji Hagiwara, J. Okabe, M. Ziemann, B. Drew +12 more
2025Diabetes9 citations Open access
Semantic Scholar
Targeted deletion of NADPH-Oxidase Nox4 from proximal tubules is dispensable for diabetic kidney disease development.
V. Thallas-Bonke, Sih-Min Tan, Runa Lindblom, M. Snelson +15 more
2020Nephrology, Dialysis and Transplantation8 citations
Semantic Scholar
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)
Ao-Wen Zhuang, F. Yap, Danielle J. Borg, D. McCarthy +7 more
2021Endocrinology, Diabetes & Metabolism6 citations Open access
Semantic Scholar
Proximal tubular deletion of superoxide dismutase-2 reveals disparate effects on kidney function in diabetes
Inez A. Trambas, Lilliana Bowen, V. Thallas-Bonke, M. Snelson +11 more
2025Redox Biology5 citations Open access
Semantic Scholar
SAT-301 RESISTANT STARCH AMELIORATES ADVANCED GLYCATION ENDPRODUCT-INDUCED GUT DYSBIOSIS AND ALBUMINURIA IN A MOUSE MODEL OF TYPE 2 DIABETES
M. Snelson, Sih-Min Tan, K. Sourris, V. Thallas-Bonke +4 more
2019Kidney International Reports5 citations Open access
Semantic Scholar
Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion
Ao-Wen Zhuang, F. Yap, D. McCarthy, S. Leung +8 more
2019Scientific Reports5 citations Open access
Semantic Scholar
Disparate Effects of Diabetes and Hyperlipidemia on Experimental Kidney Disease
A. Watson, E. Gould, S. Moody, P. Sivakumaran +7 more
2020Frontiers in Physiology4 citations Open access
Semantic Scholar
EZH2 inhibition via GSK-126 mitigates EndMT and atherosclerosis in diabetes: A translational epigenetic approach
M. Aziz, K. Sourris, J. Pinzon-Cortes, Tomasz J Block +7 more
2026Science Advances2 citations Open access
Semantic Scholar
Rapid, Precise, and Clinically Relevant Quantification of Urinary Albumin and Creatinine Using a NanoDrop UV/Vis Spectrophotometer
Keith Dias, K. Sourris, Jay C Jha, Karin Jandeleit-Dahm +1 more
2025Italian National Conference on Sensors2 citations Open access
Semantic Scholar
Mini Orals
J. Qian, S. Kotwal, S. Herath, J. Erlich +26 more
2020Nephrology2 citations Open access
Semantic Scholar
Intrinsic muscle stem cell dysfunction underlies functional deficits in models of type 1 diabetes
J. D. Chung, Jennifer Trieu, B. Parker, J. H. Nguyen +12 more
2026npj Regenerative Medicine1 citations Open access
Semantic Scholar
Nox5 in Human Peripheral Blood Mononuclear Cells: A Promising Biomarker for Unstable Diabetic Vascular Disease
Tomasz J Block, K. Sourris, A. Khan, P. Kantharidis +4 more
2022American Heart Journal1 citations
Semantic Scholar
Transflection infrared spectroscopy as a rapid screening tool for urinary 8-isoprostane
Adele Kincses, K. Sourris, Muthukumar Mohan, P. Kantharidis +2 more
2022Microchemical journal (Print)1 citations
Semantic Scholar
Thermally Processed Diet-Induced Albuminuria, Complement Activation and Intestinal Permeability Are Attenuated by Resistant Starch in Experimental Diabetes
M. Snelson, Sih-Min Tan, V. Thallas-Bonke, K. Sourris +5 more
20211 citations Open access
Semantic Scholar
Diabetic Nephropathy: Current and Novel Therapeutic Approaches to Prevent Its Development and Progression
K. Sourris, J. Forbes
20121 citations Open access
Semantic Scholar
Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes
J. M. Forbes, J. Söderlund, F. Yap, M. Knip +14 more
2011Diabetologia1 citations Open access
Semantic Scholar
Regulation of renal receptor for advanced glycation end products (RAGE) via paracrine estrogens
Brooke E. Harcourt, M. Coughlan, A. L. Morley, J. Pete +10 more
20101 citations
Semantic Scholar

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