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P. Piguet · SciRah

Researcher profile · Semantic Scholar

P. Piguet

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P. Piguet — researcher profile on SciRah

h-index: 47
Works: 108
Citations: 9,883

Most-cited papers

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection.
V. Kindler, A. Sappino, G. Grau, P. Piguet +1 more
1989Cell1,344 citations
Semantic Scholar
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria.
G. E. Grau, L. Fajardo, P. Piguet, B. Allet +2 more
1987Science767 citations
Semantic Scholar
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
P. Piguet, M. Collart, G. Grau, Y. Kapanci +1 more
1989Journal of Experimental Medicine602 citations Open access
Semantic Scholar
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease
P. Piguet, G. E. Grau, B. Allet, P. Vassalli
1987Journal of Experimental Medicine572 citations Open access
Semantic Scholar
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.
Y. Miyazaki, K. Araki, C. Vesin, Irène Garcia +4 more
1995Journal of Clinical Investigation377 citations Open access
Semantic Scholar
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions
P. Piguet, G. Grau, C. Hauser, P. Vassalli
1991Journal of Experimental Medicine327 citations Open access
Semantic Scholar
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.
G. E. Grau, H. Heremans, P. Piguet, P. Pointaire +3 more
1989Proceedings of the National Academy of Sciences of the United States of America323 citations Open access
Semantic Scholar
Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice.
P. Piguet, C. Vesin
1994European Respiratory Journal288 citations Open access
Semantic Scholar
Oxygen toxicity in mouse lung: pathways to cell death.
C. Barazzone, S. Horowitz, Y. Donati, I. Rodriguez +1 more
1998American Journal of Respiratory Cell and Molecular Biology281 citations Open access
Semantic Scholar
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria.
G. E. Grau, P. Piguet, H. Engers, J. A. Louis +2 more
1986Journal of Immunology257 citations
Semantic Scholar
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.
P. Piguet, G. E. Grau, C. Vesin, H. Loetscher +2 more
1992Immunology255 citations
Semantic Scholar
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide‐induced lethality
W. Lesslauer, H. Tabuchi, R. Gentz, M. Brockhaus +6 more
1991European Journal of Immunology248 citations
Semantic Scholar
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica.
P. Piguet, C. Vesin, G. Grau, Robert C. Thompson
1993Cytokine219 citations
Semantic Scholar
Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis.
P. Piguet, C. Ribaux, V. Karpuz, G. Grau +1 more
1993American Journal of Pathology191 citations
Semantic Scholar
Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis.
P. Piguet, G. Grau, P. Vassalli
1990American Journal of Pathology158 citations
Semantic Scholar
Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury.
Constance Barazzone, D. Belin, P. Piguet, J. Vassalli +1 more
1996Journal of Clinical Investigation144 citations Open access
Semantic Scholar
Role of ICAM-1 (CD54) in the development of murine cerebral malaria.
N. Favre, Chen Da Laperousaz, B. Ryffel, Niklaus A. Weiss +4 more
1999Microbes and infection143 citations Open access
Semantic Scholar
TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction.
G. Grau, F. Tacchini-Cottier, C. Vesin, G. Milon +3 more
1993European Cytokine Network142 citations
Semantic Scholar
Late administration of monoclonal antibody to leukocyte function‐antigen 1 abrogates incipient murine cerebral malaria
G. E. Grau, P. Pointaire, P. Piguet, C. Vesin +4 more
1991European Journal of Immunology140 citations
Semantic Scholar
Corynebacterium parvum- and Mycobacterium bovis bacillus Calmette-Guerin-induced granuloma formation is inhibited in TNF receptor I (TNF-RI) knockout mice and by treatment with soluble TNF-RI.
G. Senaldi, Songmei Yin, C. L. Shaklee, P. Piguet +2 more
1996Journal of Immunology135 citations Open access
Semantic Scholar
Keratinocyte growth factor protects alveolar epithelium and endothelium from oxygen-induced injury in mice.
C. Barazzone, Y. Donati, A. Rochat, C. Vesin +3 more
1999American Journal of Pathology122 citations Open access
Semantic Scholar
TNF‐induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
P. Piguet, C. Vesin, Jane Guo, Y. Donati +1 more
1998European Journal of Immunology112 citations Open access
Semantic Scholar
Prevention of experimental cerebral malaria by anticytokine antibodies. Interleukin 3 and granulocyte macrophage colony-stimulating factor are intermediates in increased tumor necrosis factor production and macrophage accumulation
G. E. Grau, Vincent Kindler, P. Piguet, Paul-Henri Lambert +1 more
1988Journal of Experimental Medicine96 citations Open access
Semantic Scholar
Thrombocytopenia in an animal model of malaria is associated with an increased caspase-mediated death of thrombocytes
P. Piguet, C.-D. Kan, C. Vesin
2002Apoptosis91 citations
Semantic Scholar
Role of polymorphonuclear neutrophil leukocytes and their integrin CD11a (LFA-1) in the pathogenesis of severe murine malaria
G. Senaldi, C. Vesin, R. Chang, G. E. Grau +1 more
1994Infection and Immunity90 citations Open access
Semantic Scholar
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia
G. E. Grau, K. Frei, P. Piguet, A. Fontana +4 more
1990Journal of Experimental Medicine86 citations Open access
Semantic Scholar
Functional analysis of T cell subsets from mice bearing the lpr gene.
J. Davignon, Ralph C. Budd, Rhodri Ceredig, P. Piguet +4 more
1985Journal of Immunology86 citations Open access
Semantic Scholar
Post-thymic T lymphocyte maturation during ontogenesis
P. Piguet, C. Irlé, E. Kollatte, P. Vassalli
1981Journal of Experimental Medicine82 citations Open access
Semantic Scholar
TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk.
P. Piguet, C. Vesin, Y. Donati, C. Barazzone
1999Laboratory investigation; a journal of technical methods and pathology76 citations
Semantic Scholar
Role of TNFR1 and TNFR2 in TNF-induced platelet consumption in mice.
F. Tacchini-Cottier, C. Vesin, M. Redard, W. Buurman +1 more
1998Journal of Immunology75 citations Open access
Semantic Scholar
Role of CD40-CVD40L in mouse severe malaria.
P. Piguet, Chen Kan, C. Vesin, A. Rochat +2 more
2001American Journal of Pathology74 citations Open access
Semantic Scholar
Immunosuppressor cells from newborn mouse spleen are macrophages differentiating in vitro from monoblastic precursors
P. Piguet, C. Irlé, P. Vassalli
1981European Journal of Immunology73 citations
Semantic Scholar
Delayed Mortality and Attenuated Thrombocytopenia Associated with Severe Malaria in Urokinase- and Urokinase Receptor-Deficient Mice
P. Piguet, Chen Da Laperrousaz, C. Vesin, F. Tacchini-Cottier +2 more
2000Infection and Immunity72 citations Open access
Semantic Scholar
Platelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo.
E. Yi, H. Lee, S. Yin, P. Piguet +5 more
1996American Journal of Pathology72 citations
Semantic Scholar
Tumor necrosis factor alpha is involved in mouse growth and lymphoid tissue development
S. de Kossodo, G. E. Grau, T. Daneva, P. Pointaire +6 more
1992Journal of Experimental Medicine72 citations Open access
Semantic Scholar
Effective treatment of the pulmonary fibrosis elicited in mice by bleomycin or silica with anti-CD-11 antibodies.
P. Piguet, H. Rosen, C. Vesin, G. E. Grau
1993American Review of Respiratory Disease68 citations
Semantic Scholar
Intravenous keratinocyte growth factor protects against experimental pulmonary injury.
Jane Guo, Eunhee S. Yi, Andrew M. Havill, I. Sarosi +5 more
1998American Journal of Physiology66 citations
Semantic Scholar
Significance of cytokine production and adhesion molecules in malarial immunopathology.
G. Grau, G. Bieler, P. Pointaire, S. de Kossodo +4 more
1990Immunology Letters62 citations
Semantic Scholar
Cytokines involved in pulmonary fibrosis.
P. Piguet
1993International Review of Experimental Pathology58 citations
Semantic Scholar
Dietary supplementation with fish oil enhances in vivo synthesis of tumor necrosis factor.
Hernan R. Chang, D. Arsenijevic, Jean-Claude Pechère, P. Piguet +3 more
1992Immunology Letters58 citations
Semantic Scholar
Immunopathology of thrombocytopenia in experimental malaria.
G. E. Grau, P. Piguet, D. Gretener, C. Vesin +1 more
1988Immunology56 citations
Semantic Scholar
Activation of platelet caspases by TNF and its consequences for kinetics.
P. Piguet, C. Vesin, Chen Kan
2002Cytokine54 citations
Semantic Scholar
An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium
P. Piguet, C. Vesin, J. Ryser, G. Senaldi +2 more
1993Infection and Immunity51 citations Open access
Semantic Scholar
Role of the Tumor Necrosis Factor Receptor 2 (TNFR2) in Cerebral Malaria in Mice
P. Piguet, Chen-Da Kan, C. Vesin
2002Laboratory Investigation50 citations Open access
Semantic Scholar
Hyperoxia induces platelet activation and lung sequestration: an event dependent on tumor necrosis factor-alpha and CD11a.
C. Barazzone, F. Tacchini-Cottier, C. Vesin, A. Rochat +1 more
1996American Journal of Respiratory Cell and Molecular Biology47 citations
Semantic Scholar
Hyperoxia increases leptin production: a mechanism mediated through endogenous elevation of corticosterone.
C. Barazzone-Argiroffo, P. Muzzin, Y. Donati, Chen Kan +2 more
2001American Journal of Physiology - Lung cellular and Molecular Physiology46 citations Open access
Semantic Scholar
Resistance of TNF/LTα double deficient mice to bleomycin‐induced fibrosis
P. Piguet, S. Kaufman, C. Barazzone, M. Muller +2 more
199746 citations Open access
Semantic Scholar
Pulmonary platelet trapping induced by bleomycin: correlation with fibrosis and involvement of the beta 2 integrins.
P. Piguet, C. Vesin
1994International journal of experimental pathology (Print)46 citations
Semantic Scholar
Urokinase receptor (uPAR, CD87) is a platelet receptor important for kinetics and TNF-induced endothelial adhesion in mice.
P. Piguet, C. Vesin, Y. Donati, F. Tacchini-Cottier +2 more
1999Circulation45 citations Open access
Semantic Scholar
Involvement of tumour necrosis factor and other cytokines in immune-mediated vascular pathology.
G. Grau, P. Piguet, P. Vassalli, P. Lambert
1989International Archives of Allergy and Applied Immunology42 citations
Semantic Scholar

Frequent co-authors

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C. Vesin×22
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P. Vassalli×13
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G. Grau×12
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G. E. Grau×12
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C. Barazzone — researcher profile on SciRah

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Paul-Henri Lambert×6

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Pierre Vassalli×6

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Pierre Vassalli — researcher profile on SciRah

F. Tacchini-Cottier×6

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F. Tacchini-Cottier — researcher profile on SciRah

P. Pointaire×5

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P. Pointaire — researcher profile on SciRah

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Chen Kan — researcher profile on SciRah

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Y. Kapanci — researcher profile on SciRah