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H. Jumaa · SciRah

Researcher profile · Semantic Scholar

H. Jumaa

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H. Jumaa — researcher profile on SciRah

h-index: 55
Works: 192
Citations: 9,703

Most-cited papers

Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function
Supriya Sen, H. Jumaa, N. Webster
2013Nature Communications144 citations Open access
Semantic Scholar
Responsiveness of B cells is regulated by the hinge region of IgD
Rudolf Übelhart, E. Hug, Martina P. Bach, Thomas Wossning +10 more
2015Nature Immunology128 citations
Semantic Scholar
B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation
P. Maity, A. Blount, H. Jumaa, O. Ronneberger +2 more
2015Science Signaling127 citations
Semantic Scholar
Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia
K. Althaus, P. Möller, Gunalp Uzun, Anurag Singh +31 more
2021Haematologica121 citations Open access
Semantic Scholar
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
C. Minici, M. Gounari, Rudolf Übelhart, L. Scarfò +11 more
2017Nature Communications121 citations Open access
Semantic Scholar
Deletion of Splicing Factor SRSF3 in Hepatocytes Predisposes to Hepatocellular Carcinoma in Mice
Supriya Sen, Magda Langiewicz, H. Jumaa, Nicholas J. G. Webster
2014Hepatology107 citations Open access
Semantic Scholar
B cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies
G. Xiao, Lai N. Chan, Lars Klemm, D. Braas +16 more
2018Cell106 citations Open access
Semantic Scholar
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells
Seyedmehdi Shojaee, Lai N. Chan, M. Buchner, V. Cazzaniga +13 more
2016Nature Medicine105 citations Open access
Semantic Scholar
Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia
Zhengshan Chen, Seyedmehdi Shojaee, M. Buchner, H. Geng +22 more
2015Nature89 citations Open access
Semantic Scholar
Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma.
D. Schneider, Marcus Dühren-von Minden, Alabbas Alkhatib, Corinna S. Setz +12 more
2015Blood81 citations Open access
Semantic Scholar
CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor
M. Becker, E. Hobeika, H. Jumaa, M. Reth +1 more
2017Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling
P. Maity, Mayas Bilal, M. Koning, Marc Young +34 more
2020Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Zhengshan Chen, Seyedmehdi Shojaee, M. Buchner, H. Geng +25 more
201670 citations
Semantic Scholar
Pre-BCR Signaling In Precursor B-cell Acute Lymphoblastic Leukemia regulates PI3K/AKT, FOXO1, and MYC, and can be targeted by SYK inhibition
S. Köhrer, O. Havránek, F. Seyfried, C. Hurtz +18 more
2016Leukemia69 citations Open access
Semantic Scholar
Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia.
Niuscha Yaktapour, Rudolf Übelhart, J. Schüler, K. Aumann +7 more
2013Blood65 citations
Semantic Scholar
Cancer Biology and Signal Transduction PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival ( PIM 2 / 3 ) and CXCR 4-Mediated Microenvironmental Interactions ( PIM 1 )
Sarah Decker, Johannes Finter, A. J. Forde, S. Kissel +13 more
201463 citations
Semantic Scholar
Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.
S. Iacovelli, E. Hug, S. Bennardo, M. Duehren-von Minden +17 more
2015Blood61 citations Open access
Semantic Scholar
PI3K induces B-cell development and regulates B cell identity
Hend Abdelrasoul, Markus Werner, Corinna S. Setz, K. Okkenhaug +1 more
2018Scientific Reports55 citations Open access
Semantic Scholar
The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex
E. Dolezal, S. Infantino, F. Drepper, Theresa Börsig +9 more
2017Nature Immunology52 citations
Semantic Scholar
An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
M. Harms, Monica M. W. Habib, Simona Nemska, A. Nicolò +15 more
2020bioRxiv44 citations Open access
Semantic Scholar
IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia.
A. Alsadeq, L. Lenk, Anila Vadakumchery, A. Cousins +12 more
2018Blood43 citations Open access
Semantic Scholar
Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR
Corinna S. Setz, Ahmad Khadour, Valerio Renna, Joseena Iype +9 more
2019EMBO Journal38 citations Open access
Semantic Scholar
Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development
D. Tsiantoulas, M. Kiss, Barbara Bartolini-Gritti, A. Bergthaler +3 more
2017Scientific Reports38 citations Open access
Semantic Scholar
Control of B Cell Responsiveness by Isotype and Structural Elements of the Antigen Receptor.
E. Hobeika, P. Maity, H. Jumaa
2016Trends in immunology35 citations
Semantic Scholar
Activation loop phosphorylation regulates B‐Raf in vivo and transformation by B‐Raf mutants
Martin Köhler, M. Röring, B. Schorch, Katharina Heilmann +13 more
2015EMBO Journal35 citations Open access
Semantic Scholar
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia
L. Lenk, M. Carlet, F. Vogiatzi, L. Spory +19 more
2021Communications Biology33 citations Open access
Semantic Scholar
PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis
Corinna S. Setz, E. Hug, Ahmad Khadour, Hend Abdelrasoul +3 more
2018Cell Reports31 citations Open access
Semantic Scholar
Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins
Isabel Wilhelm, Ella Levit-Zerdoun, J. Jakob, S. Villringer +12 more
2019Science Signaling30 citations Open access
Semantic Scholar
Rheumatoid factor IgM autoantibodies control IgG homeostasis
A. Nicolò, Timm Amendt, Omar El Ayoubi, Marc Young +4 more
2022Frontiers in Immunology28 citations Open access
Semantic Scholar
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
T. Sadras, Mickaël Martin, K. Kume, Mark E. Robinson +26 more
2021Molecules and Cells27 citations Open access
Semantic Scholar
Autoreactivity and the positive selection of B cells
Rudolf Übelhart, H. Jumaa
2015European Journal of Immunology27 citations Open access
Semantic Scholar
Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation
E. Hug, E. Hobeika, M. Reth, H. Jumaa
2014Oncogene25 citations
Semantic Scholar
CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia
F. Ketzer, Hend Abdelrasoul, Mona Vogel, R. Marienfeld +4 more
2022Oncogenesis21 citations Open access
Semantic Scholar
Primary Immune Responses and Affinity Maturation Are Controlled by IgD
Timm Amendt, Omar El Ayoubi, A. Linder, Gabriele Allies +3 more
2021Frontiers in Immunology20 citations Open access
Semantic Scholar
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia
Hend Abdelrasoul, Anila Vadakumchery, Markus Werner, L. Lenk +17 more
2020Nature Communications20 citations Open access
Semantic Scholar
Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor
Joseena Iype, Moumita Datta, Ahmad Khadour, Rudolf Übelhart +6 more
2019Journal of Immunology20 citations Open access
Semantic Scholar
Autoreactive antibodies control blood glucose by regulating insulin homeostasis
Timm Amendt, Gabriele Allies, A. Nicolò, Omar El Ayoubi +5 more
2022Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens
Nereida Jiménez de Oya, M. De Giovanni, J. Fioravanti, Rudolf Übelhart +9 more
2017EMBO Molecular Medicine18 citations Open access
Semantic Scholar
The role of BCR isotype in B-cell development and activation.
Elena Surova, H. Jumaa
2014Advances in Immunology18 citations
Semantic Scholar
A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development
Alexandra Flemming, Qi-Quan Huang, Jian-Ping Jin, H. Jumaa +1 more
2015PLoS ONE17 citations Open access
Semantic Scholar
Memory IgM protects endogenous insulin from autoimmune destruction
Timm Amendt, H. Jumaa
2021EMBO Journal16 citations Open access
Semantic Scholar
Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia
Marco Benkisser-Petersen, M. Buchner, Arlette Dörffel, Marcus Dühren-von Minden +11 more
2016PLoS ONE15 citations Open access
Semantic Scholar
Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell
Rashmi Kumar, Martina P. Bach, F. Mainoldi, Mikako Maruya +6 more
2015Proceedings of the National Academy of Sciences of the United States of America15 citations Open access
Semantic Scholar
B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia
A. Mazzarello, Eva Gentner-Göbel, Marcus Dühren-von Minden, Tatyana N. Tarasenko +11 more
2021Journal of Clinical Investigation14 citations Open access
Semantic Scholar
Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4
P. Maity, Moumita Datta, A. Nicolò, H. Jumaa
2018Frontiers in Immunology14 citations Open access
Semantic Scholar
Assembly and Function of the Precursor B-Cell Receptor.
Rudolf Übelhart, Markus Werner, H. Jumaa
2015Current Topics in Microbiology and Immunology14 citations Open access
Semantic Scholar
Premature Terminal Differentiation Protects from Deregulated Lymphocyte Activation by ITK-Syk
Martina P. Bach, E. Hug, Markus Werner, J. Holch +7 more
2014Journal of Immunology11 citations Open access
Semantic Scholar
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia
Edwin Quinten, Julieta H. Sepulveda-Yanez, M. Koning, Janneke A. Eken +17 more
2023Haematologica10 citations Open access
Semantic Scholar
B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia
Vera Schmid, Ahmad Khadour, N. Ahmed, Caroline Brandl +4 more
2022Haematologica9 citations Open access
Semantic Scholar
Adaptive tolerance: Protection through self‐recognition
Timm Amendt, H. Jumaa
2022Bioessays6 citations Open access
Semantic Scholar

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M. Reth×10
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M. Reth — researcher profile on SciRah
E. Hobeika×9
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E. Hobeika — researcher profile on SciRah
Rudolf Übelhart×8
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Rudolf Übelhart — researcher profile on SciRah
P. Maity×8
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M. Müschen — researcher profile on SciRah

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Corinna S. Setz×6

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K. Zirlik — researcher profile on SciRah

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H. Veelken — researcher profile on SciRah

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E. Hug — researcher profile on SciRah