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K. Kume · SciRah

Researcher profile · Semantic Scholar

K. Kume

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K. Kume — researcher profile on SciRah

h-index: 15
Works: 77
Citations: 656

Most-cited papers

A Distinct Subpopulation of Bone Marrow Mesenchymal Stem Cells, Muse Cells, Directly Commit to the Replacement of Liver Components
Hirokatsu Katagiri, Yoshihiro Kushida, Makoto Nojima, Yasumasa Kuroda +9 more
2016American Journal of Transplantation83 citations Open access
Semantic Scholar
IFITM3 functions as PIP3-scaffold to amplify PI3K signaling in B-cells
Jaewoong Lee, Mark E. Robinson, Ning Ma, Dewan Artadji +25 more
2020Nature72 citations Open access
Semantic Scholar
Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells
Jaewoong Lee, Mark E. Robinson, Ning Ma, Dewan Artadji +25 more
2021Nature65 citations Open access
Semantic Scholar
Signaling input from divergent pathways subverts B-cell transformation
Lai N. Chan, Mark A. Murakami, Mark E. Robinson, Rebecca Caeser +25 more
2020Nature56 citations Open access
Semantic Scholar
Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel
Kei A. Sato, T. Hachiya, T. Iwaya, K. Kume +7 more
2016PLoS ONE48 citations Open access
Semantic Scholar
Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
T. Iwaya, T. Fukagawa, Yutaka Suzuki, Y. Takahashi +16 more
2013Clinical Cancer Research48 citations Open access
Semantic Scholar
α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15
K. Kume, Miyuki Ikeda, Sawako Miura, Kohei Ito +8 more
2016Scientific Reports37 citations Open access
Semantic Scholar
A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines
Fumitaka Endo, S. Nishizuka, K. Kume, Kazushige Ishida +6 more
2014PLoS ONE34 citations Open access
Semantic Scholar
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
T. Sadras, Mickaël Martin, K. Kume, Mark E. Robinson +26 more
2021Molecules and Cells27 citations Open access
Semantic Scholar
SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies.
Etienne Leveille, Lai N. Chan, A. Mirza, K. Kume +1 more
2022Cellular Signalling25 citations
Semantic Scholar
TAS1 trans-Acting siRNA Targets Are Differentially Regulated at Low Temperature, and TAS1 trans-Acting siRNA Mediates Temperature-Controlled At1g51670 Expression
K. Kume, K. Tsutsumi, Y. Saitoh
2010Bioscience, biotechnology and biochemistry22 citations
Semantic Scholar
W14/15 esterase gene haplotype can be a genetic landmark of cultivars and species of the genus Gentiana L
T. Hikage, Kiyomi Kogusuri, Claire Tanaka-Saito, Shuji Watanabe +6 more
2010Zeitschrift für Induktive Abstammungs- und Vererbungslehre18 citations
Semantic Scholar
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis
Lili Pan, Chao Hong, Lai N. Chan, G. Xiao +13 more
2021Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
Ductular reactions in the liver regeneration process with local inflammation after physical partial hepatectomy
Yuji Suzuki, Hirokatsu Katagiri, Ting Wang, Keisuke Kakisaka +3 more
2016Laboratory Investigation16 citations Open access
Semantic Scholar
Molecular Marker Identification for Relapse Prediction in 5-FU-Based Adjuvant Chemotherapy in Gastric and Colorectal Cancers
Kazushige Ishida, S. Nishizuka, Takehiro Chiba, Miyuki Ikeda +17 more
2012PLoS ONE15 citations Open access
Semantic Scholar
Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil
K. Ishida, Chie Ito, Y. Ohmori, K. Kume +8 more
2017Scientific Reports14 citations Open access
Semantic Scholar
Identification and functional analysis of SVP ortholog in herbaceous perennial plant Gentiana triflora: Implication for its multifunctional roles.
N. Yamagishi, K. Kume, T. Hikage, Yui Takahashi +5 more
2016Plant Science13 citations
Semantic Scholar
Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development.
T. Iwaya, G. Sawada, Suburu Amano, K. Kume +13 more
2017International Journal of Oncology9 citations Open access
Semantic Scholar
Evaluation of chemosensitivity prediction using quantitative dose–response curve classification for highly advanced/relapsed gastric cancer
Teppei Matsuo, S. Nishizuka, Kazushige Ishida, Fumitaka Endo +5 more
2013World Journal of Surgical Oncology8 citations Open access
Semantic Scholar
Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling
Jaewoong Lee, Mark E. Robinson, Ruifeng Sun, K. Kume +14 more
2023bioRxiv6 citations Open access
Semantic Scholar
Colony Lysate Arrays for Proteomic Profiling of Drug-Tolerant Persisters of Cancer Cell.
K. Kume, S. Nishizuka
2017Analytical Chemistry3 citations Open access
Semantic Scholar
Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation
K. Cosgun, Mark E. Robinson, Gauri Deb, Xin Yang +17 more
2020bioRxiv2 citations Open access
Semantic Scholar
Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis
Jaewoong Lee, G. Xiao, K. Cosgun, H. Geng +15 more
2019Blood2 citations Open access
Semantic Scholar
Systematic Protein Level Regulation via Degradation Machinery Induced by Genotoxic Drugs.
K. Kume, Kazushige Ishida, Miyuki Ikeda, Kazuhiro Takemoto +3 more
2016Journal of Proteome Research2 citations
Semantic Scholar
Color-imaging histodiagnostic approach for cancer
Akio Sugitachi, K. Otsuka, Toshimoto Kimura, M. Hakozaki +5 more
20152 citations Open access
Semantic Scholar
Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies
K. Cosgun, Huda Jumaa, Mark E. Robinson, Klaus M. Kistner +19 more
2023bioRxiv1 citations Open access
Semantic Scholar
Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies
Ruifeng Sun, Jaewoong Lee, Mark E. Robinson, K. Kume +11 more
2023Blood1 citations Open access
Semantic Scholar
Immunoglobulin Light Chains Control Permissiveness to Malignant B-Cell Transformation By RAS-Pathway Lesions
Lai N. Chan, K. Kume, C. Hurtz, Mark E. Robinson +2 more
2023Blood1 citations Open access
Semantic Scholar
Divergent MYC- and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies
K. Kume, Zhengshan Chen, Lai N. Chan, Mark E. Robinson +7 more
2022Blood1 citations Open access
Semantic Scholar
Identification of BCL6 As Synthetic Lethality in RAS-Driven B-Cell Transformation
Lai N. Chan, C. Hurtz, Etienne Leveille, K. Kume +4 more
2021Blood1 citations Open access
Semantic Scholar
Leveraging Pathway-Interference to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia
Lai N. Chan, Mark A. Murakami, C. Hurtz, K. Kume +6 more
2021Blood1 citations Open access
Semantic Scholar
Signaling input from divergent pathways subverts malignant B-cell transformation
Lai N. Chan, Mark A. Murakami, Mark E. Robinson, Rebecca Caeser +25 more
2020bioRxiv1 citations Open access
Semantic Scholar
Autonomous Ca2+ Oscillations Reflect Oncogenic Signaling in B-ALL Cells
K. Kume, Li-Ting Chen, Jaewoong Lee, M. Müschen
2019Blood1 citations Open access
Semantic Scholar
Ca2+ Oscillations and NFATC1 -Activation Enable Oncogenic Signaling in Pre-B Cell Transformation and Leukemogenesis
K. Kume, Li-Ting Chen, Jaewoong Lee, M. Müschen
20171 citations
Semantic Scholar
Abstract 1159: Downregulation of TMPRSS11B in squamous cell carcinoma
Suburu Amano, T. Iwaya, S. Nishizuka, K. Kume +5 more
20161 citations
Semantic Scholar
Abstract 5234: Tumor-unique mutation detection in cell-free DNA to monitor colorectal tumor burden using a cancer-associated gene sequencing panel
Kei A. Sato, S. Nishizuka, T. Iwaya, K. Kume +2 more
20151 citations
Semantic Scholar
Topical administration of a newly devised anticancer agent: A novel concept of cancer chemotherapy
Akio Sugitachi, N. Takahashi, K. Kume, Y. Ohmori +3 more
20141 citations
Semantic Scholar
Abstract 5201: MicroRNA 760 regulates gastric cancer progression by downregulation of histone mRNA expression
T. Iwaya, T. Fukagawa, Yutaka Suzuki, T. Sudo +8 more
20141 citations
Semantic Scholar
Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies
K. Cosgun, Mark E. Robinson, Salim Oulghazi, Liang Xu +17 more
2023Blood0 citations Open access
Semantic Scholar
Computational Discovery and Validation of NAD+ Biosynthesis As Unique Vulnerability in B-Lymphoid Malignancies
Qin Li, Mark E. Robinson, Etienne Leveille, Chang Zhang +8 more
2023Blood0 citations Open access
Semantic Scholar
MYC to BCL6 State-Transitions Determine Cell Size and Metabolic Fluctuations and Define a Novel Biorhythm in B-Cell Malignancies
Zhangliang Cheng, K. Kume, M. Müschen
2023Blood0 citations Open access
Semantic Scholar
STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia
K. Kume, Zhengshan Chen, Mark E. Robinson, Lai N. Chan +7 more
2023Blood0 citations Open access
Semantic Scholar
Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies
K. Kume, Jaewoong Lee, Zhangliang Cheng, Mark E. Robinson +8 more
2023Blood0 citations Open access
Semantic Scholar
CD25 recruits inhibitory phosphatases for feedback control of B-cell receptor signaling
Ruifeng Sun, Jaewoong Lee, Mark E. Robinson, K. Kume +9 more
2023Journal of Immunology0 citations Open access
Semantic Scholar
GSK3β Inhibition Is a Unique Vulnerability in Lymphoid Malignancies
K. Cosgun, Huda Jumaa, Mark E. Robinson, Lai N. Chan +5 more
2022Blood0 citations Open access
Semantic Scholar
BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation
Lai N. Chan, C. Hurtz, Mark E. Robinson, Etienne Leveille +6 more
2022Blood0 citations
Semantic Scholar
A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling
Jaewoong Lee, K. Kume, Mark E. Robinson, Ruifeng Sun +17 more
2022Blood0 citations Open access
Semantic Scholar
Structural Basis of Feedback Control of Oncogenic Signaling in B-Lymphoid Malignancies
Jaewoong Lee, Mark E. Robinson, Ning Ma, K. Kume +9 more
2021Blood0 citations Open access
Semantic Scholar
Pharmacological Targeting of PI3K-Dependent Central Tolerance Mechanisms in Refractory Pre-Germinal Center B-Cell Malignancies
K. Kume, Jaewoong Lee, Lai N. Chan, Mark E. Robinson +3 more
2021Blood0 citations Open access
Semantic Scholar
Identification of a Conserved Intracellular Loop (CIL) Structure That Scaffolds PIP3 to Amplify Oncogenic Signaling during Malignant B-Cell Transformation
Jaewoong Lee, Mark E. Robinson, Ning Ma, T. Sadras +8 more
2021Blood0 citations Open access
Semantic Scholar

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