Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

P. Ruffini · SciRah

Researcher profile · Semantic Scholar

P. Ruffini

Share profile

P. Ruffini — researcher profile on SciRah

h-index: 25
Works: 51
Citations: 3,420

Most-cited papers

Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2
A. Biragyn, P. Ruffini, C. Leifer, E. Klyushnenkova +7 more
2002Science888 citations
Semantic Scholar
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.
A. Biragyn, P. Ruffini, C. Leifer, E. Klyushnenkova +7 more
2002Science362 citations
Semantic Scholar
Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens
A. Biragyn, Munhsuren Surenhu, De Yang, P. Ruffini +4 more
2001Journal of Immunology311 citations
Semantic Scholar
Phase Ib pilot study to evaluate reparixin in combination with weekly paclitaxel in patients with HER-2 negative metastatic breast cancer (MBC)
A. Schott, L. Goldstein, M. Cristofanilli, P. Ruffini +5 more
2017Clinical Cancer Research204 citations Open access
Semantic Scholar
Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer.
G. Perrone, P. Ruffini, V. Catalano, C. Spino +15 more
2008European Journal of Cancer204 citations
Semantic Scholar
Cardiac toxicity of high-dose chemotherapy
P. Morandi, P. Ruffini, G. Benvenuto, R. Raimondi +1 more
2005Bone Marrow Transplantation163 citations
Semantic Scholar
CXCR1/2 inhibition enhances pancreatic islet survival after transplantation.
A. Citro, E. Cantarelli, P. Maffi, R. Nano +11 more
2012Journal of Clinical Investigation151 citations Open access
Semantic Scholar
A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer
L. Goldstein, R. Perez, D. Yardley, Linda K. Han +8 more
2020Breast Cancer Research102 citations Open access
Semantic Scholar
Intralesional Treatment of Stage III Metastatic Melanoma Patients with L19–IL2 Results in Sustained Clinical and Systemic Immunologic Responses
B. Weide, T. Eigentler, A. Pflugfelder, H. Zelba +9 more
2014Cancer immunology research89 citations Open access
Semantic Scholar
CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice
A. Citro, A. Valle, E. Cantarelli, A. Mercalli +8 more
2014Diabetes87 citations
Semantic Scholar
Safety and Pharmacokinetics of Escalating Doses of Human Recombinant Nerve Growth Factor Eye Drops in a Double-Masked, Randomized Clinical Trial
M. Ferrari, F. Mantelli, M. Sacchetti, M. I. Antonangeli +5 more
2013BioDrugs79 citations Open access
Semantic Scholar
A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida)
L. Goldstein, M. Mansutti, C. Lévy, Jenny C. Chang +49 more
2021Breast Cancer Research and Treatment77 citations Open access
Semantic Scholar
Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling
L. Brandolini, L. Cristiano, Alessia Fidoamore, M. de Pizzol +12 more
2015OncoTarget74 citations Open access
Semantic Scholar
Idiotypic vaccination for B-cell malignancies as a model for therapeutic cancer vaccines: from prototype protein to second generation vaccines.
P. Ruffini, S. Neelapu, L. Kwak, A. Biragyn
2002Haematologica68 citations
Semantic Scholar
Loco-regional immunotherapy with recombinant interleukin-2 and adherent lymphokine-activated killer cells (A-LAK) in recurrent glioblastoma patients
A. Boiardi, A. Silvani, P. Ruffini, L. Rivoltini +3 more
1994Cancer Immunology and Immunotherapy61 citations
Semantic Scholar
Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo.
A. Biragyn, P. Ruffini, M. Coscia, Linda K. Harvey +4 more
2004Blood60 citations Open access
Semantic Scholar
The CXCL8-CXCR1/2 Axis as a Therapeutic Target in Breast Cancer Stem-Like Cells
P. Ruffini
2019Frontiers in Oncology58 citations Open access
Semantic Scholar
Factors, including transforming growth factor β, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells
P. Ruffini, L. Rivoltini, A. Silvani, A. Boiardi +1 more
1993Cancer Immunology and Immunotherapy44 citations Open access
Semantic Scholar
Ladarixin, an inhibitor of the interleukin‐8 receptors CXCR1 and CXCR2, in new‐onset type 1 diabetes: A multicentre, randomized, double‐blind, placebo‐controlled trial
L. Piemonti, B. Keymeulen, P. Gillard, T. Linn +11 more
2022Diabetes, obesity and metabolism43 citations Open access
Semantic Scholar
Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes
P. Maffi, T. Lundgren, G. Tufveson, E. Rafael +10 more
2020Diabetes Care39 citations Open access
Semantic Scholar
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines.
P. Ruffini, G. Grødeland, A. Fredriksen, B. Bogen
2010Vaccine35 citations
Semantic Scholar
Armed antibodies for cancer treatment: a promising tool in a changing era
R. Danielli, R. Patuzzo, P. Ruffini, A. Maurichi +4 more
2014Cancer Immunology and Immunotherapy31 citations Open access
Semantic Scholar
In vitro and in vivo stability and anti-tumour efficacy of an anti-EGFR/anti-CD3 F(ab')2 bispecific monoclonal antibody.
Donatella R. M. Negri, E. Tosi, O. Valota, S. Ferrini +6 more
1995British Journal of Cancer29 citations Open access
Semantic Scholar
Review: To What Extent are T Cells Tolerant to Immunoglobulin Variable Regions?
B. Bogen, P. Ruffini
2009Scandinavian Journal of Immunology28 citations Open access
Semantic Scholar
Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research.
B. Bogen, P. Ruffini, A. Corthay, A. Fredriksen +5 more
2006Haematologica27 citations
Semantic Scholar
Chemotherapy-related cardiotoxicity: new diagnostic and preventive strategies.
G. Benvenuto, R. Ometto, A. Fontanelli, A. Fortunato +3 more
2003Italian heart journal: official journal of the Italian Federation of Cardiology24 citations
Semantic Scholar
Immunotherapy of multiple myeloma.
P. Ruffini, L. Kwak
2001Seminars in hematology (Print)15 citations
Semantic Scholar
[Assessment of cardiotoxicity of high dose cyclophosphamide with electrocardiographic, echocardiographic, and troponin I monitoring in patients with breast tumors].
G. Benvenuto, L. La Vecchia, P. Morandi, P. Ruffini +1 more
2000Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology9 citations
Semantic Scholar
Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer
L. Goldstein, R. Perez, D. Yardley, Linda K. Han +8 more
2020Breast Cancer Research7 citations Open access
Semantic Scholar
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
P. Ruffini, A. Os, R. Dolcetti, G. Tjønnfjord +2 more
2014Journal of Translational Medicine7 citations Open access
Semantic Scholar
Genetic idiotypic and tumor cell-based vaccine strategies for indolent non Hodgkin's lymphoma.
P. Ruffini, M. Di Nicola, C. Carlo-Stella, S. Siena +1 more
2005Current Gene Therapy6 citations
Semantic Scholar
The therapeutic potential of an allosteric non‐competitive CXCR1/2 antagonist for diabetic nephropathy
C. Grasselli, S. Bombelli, V. D'Esposito, M. F. Di Tolla +11 more
2023Diabetes/Metabolism Research Reviews5 citations Open access
Semantic Scholar
SAT0232 A Phase IB Clinical Trial in Rheumatoid Arthritis of Dekavil (F8-IL10), A Novel Anti-Inflammatory Immunocytokine
M. Galeazzi, L. Bazzichi, G. Sebastiani, D. Neri +12 more
20145 citations
Semantic Scholar
Abstract OT2-3-01: Phase Ib pilot study to evaluate reparixin in combination with chemotherapy with weekly paclitaxel in patients with HER-2 negative metastatic breast cancer (MBC)
A. Schott, M. Wicha, M. Cristofanilli, P. Ruffini +3 more
20125 citations
Semantic Scholar
Abstract P6-03-01: A phase Ib study of the CXCR1/2 inhibitor reparixin in combination with weekly paclitaxel in metastatic HER2 negative breast cancer – First analysis
A. Schott, M. Wicha, R. Perez, G. Kato +7 more
20154 citations
Semantic Scholar
A phase II study of intratumoral application of L19IL2/L19TNF in melanoma patients in clinical stage III or stage IV M1a with presence of injectable cutaneous and/or subcutaneous lesions.
R. Danielli, R. Patuzzo, A. D. di Giacomo, G. Gallino +10 more
20144 citations
Semantic Scholar
Intralesional treatment of stage III metastatic melanoma patients with L19-IL2: Clinical and systemic immunological responses.
D. Neri, B. Weide, T. Eigentler, A. Pflugfelder +8 more
20144 citations
Semantic Scholar
Cloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera.
S. Cha, L. Kwak, P. Ruffini, H. Qin +2 more
2005JIM - Journal of Immunological Methods4 citations Open access
Semantic Scholar
Germ Cell Tumors Overexpress the Candidate Therapeutic target Cyclin B1 Independently of p53 function
U. de Giorgi, Ju-Ping Yuan, M. Moroni, S. Veronese +5 more
2015International Journal of Biological Markers3 citations Open access
Semantic Scholar
249-OR: A Randomized, Double-Blind Phase 2 Trial of the CXCR1/2 Inhibitor Ladarixin in Adult Patients with New-Onset Type 1 Diabetes
E. Bosi, P. Pozzilli, F. Giorgino, E. Cossu +8 more
20202 citations
Semantic Scholar
Association of intratumoral FOXP3-positive regulatory T cells (Tregs) with adverse prognosis in radically resected (R0), stage II- III gastric cancer (GC)
F. Graziano, P. Ruffini, G. Perrone, V. Catalano +7 more
20082 citations
Semantic Scholar
Abstract OT1-16-01: Trial In Progress: An Evaluation of FACIT-Fatigue in Patients with Locally Advanced or Metastatic Breast Cancer receiving Treatment with Taxane-based Chemotherapy
A. Fabi, S. Hager, Laura Lourdes, R. Pedersini +9 more
2023Cancer Research1 citations
Semantic Scholar
Abstract P3-11-07: A randomized phase II trial of reparixin, a CXCR1 inhibitor, in combination with paclitaxel in the treatment of mTNBC
L. Goldstein, M. Mansutti, C. Lévy, Jenny C. Chang +9 more
2020Poster Session Abstracts1 citations
Semantic Scholar
Improving cancer therapy by targeting cancer stem cells: Directions, challenges, and clinical results
P. Ruffini, V. Vaja, M. Allegretti
20151 citations Open access
Semantic Scholar
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
P. Ruffini, A. Os, R. Dolcetti, G. Tjønnfjord +2 more
2014Journal of Translational Medicine1 citations Open access
Semantic Scholar
Post-transplant complications Serum cardiac troponin I levels and ECG/Echo monitoring in breast cancer patients undergoing high-dose (7 g/m 2 ) cyclophosphamide
P. Morandi, P. Ruffini, G. Benvenuto, L. La Vecchia +2 more
20011 citations
Semantic Scholar
Abstract P5-07-09: Fatigue in patients with locally advanced or metastatic breast cancer undergoing single-agent taxane-based chemotherapy: de novo versus relapsed
A. Blaes, E. Gavioli, Renuka Wakade, Santiago Miracle +8 more
2023Cancer Research0 citations
Semantic Scholar
CXCR1/2 inhibition prevents paclitaxel- and oxaliplatin-induced peripheral neuropathy
P. Ruffini, L. Brandolini, R. Russo, A. Cimini +1 more
20160 citations
Semantic Scholar
Phase I, Randomized, Double-Masked, Vehicle-Controlled Study to Evaluate Safety, Tolerability and Pharmacokinetics of Recombinant Human Nerve Growth Factor Eye Drops in Healthy Volunteers
R. Buggage, P. Ruffini, M. Ferrari
20130 citations
Semantic Scholar
protective immunity in vivo efficiently into the class II processing pathway in vitro and induces Chemokine receptor-mediated delivery directs self-tumor antigen
S. Baskar, Ji-Ming Wang, L. Kwak, A. Biragyn +4 more
20130 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Allegretti×10
Invite
M. Allegretti — researcher profile on SciRah
L. Kwak×8
Invite
L. Kwak — researcher profile on SciRah
A. Biragyn×7
Invite
A. Biragyn — researcher profile on SciRah
L. Goldstein×7
Invite
L. Goldstein — researcher profile on SciRah

×7

Invite

S. McCanna — researcher profile on SciRah

Invite

M. Wicha — researcher profile on SciRah

L. Daffonchio×5

Invite

L. Daffonchio — researcher profile on SciRah

Invite

L. Piemonti — researcher profile on SciRah

L. Giovannoni×5

Invite

L. Giovannoni — researcher profile on SciRah

Invite

D. Neri — researcher profile on SciRah

Invite

B. Bogen — researcher profile on SciRah

Invite

A. Schott — researcher profile on SciRah