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L. Daffonchio · SciRah

Researcher profile · Semantic Scholar

L. Daffonchio

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L. Daffonchio — researcher profile on SciRah

h-index: 17
Works: 71
Citations: 868

Most-cited papers

CXCR1/2 inhibition enhances pancreatic islet survival after transplantation.
A. Citro, E. Cantarelli, P. Maffi, R. Nano +11 more
2012Journal of Clinical Investigation151 citations Open access
Semantic Scholar
CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice
A. Citro, A. Valle, E. Cantarelli, A. Mercalli +8 more
2014Diabetes87 citations
Semantic Scholar
Efficacy and safety of levodropropizine and dihydrocodeine on nonproductive cough in primary and metastatic lung cancer.
G. Luporini, S. Barni, E. Marchi, L. Daffonchio
1998European Respiratory Journal68 citations Open access
Semantic Scholar
Efficacy and tolerability of levodropropizine in adult patients with non-productive cough. Comparison with dextromethorphan.
E. Catena, L. Daffonchio
1997Pulmonary Pharmacology & Therapeutics51 citations
Semantic Scholar
Possible involvement of eicosanoids in the pharmacological action of bromelain.
M. Vellini, D. Desideri, A. Milanese, Claudio Omini +3 more
1986Arzneimittel-Forschung44 citations
Semantic Scholar
Ladarixin, an inhibitor of the interleukin‐8 receptors CXCR1 and CXCR2, in new‐onset type 1 diabetes: A multicentre, randomized, double‐blind, placebo‐controlled trial
L. Piemonti, B. Keymeulen, P. Gillard, T. Linn +11 more
2022Diabetes, obesity and metabolism43 citations Open access
Semantic Scholar
Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes
P. Maffi, T. Lundgren, G. Tufveson, E. Rafael +10 more
2020Diabetes Care39 citations Open access
Semantic Scholar
Effectiveness of carbocysteine lysine salt monohydrate on models of airway inflammation and hyperresponsiveness.
C. Asti, Gabriella Melillo, Gianfranco Caselli, L. Daffonchio +3 more
1995Pharmacological Research39 citations
Semantic Scholar
Bradykinin and substance P potentiate acetylcholine-induced bronchospasm in guinea-pig.
C. Omini, G. Brunelli, Alicia Hernandez, L. Daffonchio
1989European Journal of Pharmacology39 citations
Semantic Scholar
Pharmacological modulation of bronchial anaphylaxis induced by aerosol challenge in anaesthetized guinea‐pigs
L. Daffonchio, I. W. Lees, A. Payne, B. Whittle
1987British Journal of Pharmacology34 citations Open access
Semantic Scholar
Inactivation of endothelin by polymorphonuclear leukocyte-derived lytic enzymes.
Paola Patrignani, A. Del Maschio, G. Bazzoni, L. Daffonchio +6 more
1991Blood31 citations
Semantic Scholar
Defibrotide, an antithrombotic substance which prevents myocardial contracture in ischemic rabbit heart.
Ferruccio Berti, G. Rossoni, Claudio Omini, G. Folco +3 more
1987European Journal of Pharmacology30 citations
Semantic Scholar
Effects of levodropropizine on vagal afferent C‐fibres in the cat
H. Shams, L. Daffonchio, P. Scheid
1996British Journal of Pharmacology27 citations Open access
Semantic Scholar
Stimulation of Cl- secretion by the mucoactive drug S-carboxymethylcysteine-lysine salt in the isolated rabbit trachea.
B. Colombo, P. Turconi, L. Daffonchio, G. Fedele +2 more
1994European Respiratory Journal26 citations Open access
Semantic Scholar
Airway hyperreactivity induced by active cigarette smoke exposure in guinea-pigs: possible role of sensory neuropeptides.
L. Daffonchio, A. Hernandez, L. Gallico, C. Omini
1990Pulmonary Pharmacology26 citations
Semantic Scholar
S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium
F. Guizzardi, S. Rodighiero, A. Binelli, S. Saino +10 more
2005Journal of molecular medicine25 citations
Semantic Scholar
Airway hyperreactivity follows anaphylactic microshock in anaesthetized guinea-pigs.
L. Daffonchio, A. Payne, I. W. Lees, B. Whittle
1989European Journal of Pharmacology23 citations
Semantic Scholar
Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine.
G. Ciabattoni, A. Boss, L. Daffonchio, J. Daugherty +4 more
1987Advances in prostaglandin, thromboxane, and leukotriene research22 citations
Semantic Scholar
Release of Contracting Autacoids by Aortae of Normal and Atherosclerotic Rabbits
P. Patrignani, L. Daffonchio, Alicia Hernandez, R. de Caterina +2 more
1992Journal of Cardiovascular Pharmacology21 citations Open access
Semantic Scholar
Passive cigarette smoke exposure induces airway hyperreactivity to histamine but not to acetylcholine in guinea-pigs.
C. Omini, A. Hernandez, G. Zuccari, G. Clavenna +1 more
1990Pulmonary Pharmacology21 citations
Semantic Scholar
Interleukin-1β: A possible mediator of lung inflammation and airway hyperreactivity
A. Hernandez, C. Omini, L. Daffonchio
199119 citations
Semantic Scholar
Immediate anaphylactic bronchoconstriction induces airway hyperreactivity in anaesthetized guinea‐pigs
L. Daffonchio, A. Payne, I. W. Lees, B. Whittle
1988British Journal of Pharmacology18 citations Open access
Semantic Scholar
Prostaglandin D2 (PGD2) potentiates cholinergic responsiveness in guinea-pig trachea.
C. Omini, G. Brunelli, L. Daffonchio, C. Mapp +2 more
1986Journal of autonomic pharmacology15 citations
Semantic Scholar
Antioxidant activity of carbocysteine lysine salt monohydrate.
S. Pinamonti, L. Venturoli, M. Leis, M. Chicca +6 more
2001Panminerva Medica (Testo stampato)13 citations
Semantic Scholar
Effectiveness of levodropropizine against cigarette smoke-induced airway hyperreactivity: possible mechanism.
L. Daffonchio, Alicia Hernandez, Gabriella Melillo, Gaetano Clavenna +1 more
1993European Journal of Pharmacology13 citations
Semantic Scholar
Changes in airway reactivity to exogenous and endogenous acetylcholine and substance P after anaphylactic bronchoconstriction in anaesthetized guinea-pigs.
P. Nieri, L. Daffonchio, C. Omini, E. Martinotti +1 more
1992Journal of autonomic pharmacology13 citations
Semantic Scholar
Protective effect of ketoprofen lysine salt on interleukin-1β and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation
L. Daffonchio, R. Novellini, S. Bertuglia
2002Inflammation Research12 citations
Semantic Scholar
S‐Carbocysteine‐lysine salt monohydrate and cAMP cause non‐additive activation of the cystic fibrosis transmembrane regulator channel in human respiratory epithelium
G. Meyer, S. Doppierio, L. Daffonchio, D. Cremaschi
1997FEBS Letters12 citations
Semantic Scholar
Targeting CXCR1/2 in the first multicenter, double‐blinded, randomized trial in autologous islet transplant recipients
P. Witkowski, M. Wijkstrom, P. Bachul, Katherine A. Morgan +10 more
2021American Journal of Transplantation11 citations Open access
Semantic Scholar
Arachidonic acid metabolites and lung β-adrenoceptor desensitization
M. Abbracchio, L. Daffonchio, C. Omini
198610 citations
Semantic Scholar
Positive interaction between leukotriene C4 and histamine and other mediators on vascular tissues.
Claudio Omini, L. Daffonchio, G. Brunelli, Ferruccio Berti
1985Prostaglandins10 citations
Semantic Scholar
Effect of frusemide on Cl- channel in rat peritoneal mast cells.
G. Meyer, S. Doppierio, P. Vallin, L. Daffonchio
1996European Respiratory Journal8 citations Open access
Semantic Scholar
Effect of 3'-hydroxyfarrerol on airway hyperreactivity induced by acute cigarette smoke exposure in guinea pigs.
Alicia Hernandez, L. Daffonchio, Teresa Vigano, Ornella Letari +1 more
1994European Journal of Pharmacology8 citations
Semantic Scholar
Effect of S-carboxymethylcysteine lysine salt on mucociliary clearance in rabbits with secretory cell metaplasia.
L. Daffonchio, M. D. de Santi, C. Gardi, G. Lungarella +1 more
1994Research Communications in Molecular Pathology and Pharmacology8 citations
Semantic Scholar
Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea.
Isao Yamawaki, P. Geppetti, C. Bertrand, Olivier Huber +3 more
1993European Journal of Pharmacology8 citations
Semantic Scholar
Arachidonic acid metabolites induced β-adrenoceptor densitization in rat lung in vitro
L. Daffonchio, M. Abbracchio, Alicia Hernandez, E. Giani +2 more
19858 citations
Semantic Scholar
Levodropropizine does not affect P0.1 and breathing pattern in healthy volunteers and patients with chronic respiratory impairment.
Claudio Bruschi, Paola Crotti, E. Dacosto, Francesco Fanfulla +2 more
2003Pulmonary Pharmacology & Therapeutics7 citations
Semantic Scholar
Nedocromil sodium prevents airway hyperreactivity induced by cigarette smoke in anaesthetized guinea-pigs.
L. Daffonchio, A. Hernandez, C. Omini
1992Pulmonary Pharmacology7 citations
Semantic Scholar
Active sensitisation modifies β-adrenoceptor reactivity in guinea-pig trachea
L. Daffonchio, A. Hernandez, G. Brunelli, C. Omini
19897 citations
Semantic Scholar
Rat pulmonary artery responses to some mediators of anaphylaxis: modifications by indomethacin.
L. Daffonchio, M. Fano, Claudio Omini
1984Pharmacological Research Communications7 citations
Semantic Scholar
Effects of a new foam formulation of ketoprofen lysine salt in experimental models of inflammation and hyperalgesia.
L. Daffonchio, A. Bestetti, Gaetano Clavenna, G. Fedele +2 more
1995Arzneimittel-Forschung6 citations
Semantic Scholar
Effect of a mucoactive compound (CO 1408) on airway hyperreactivity and inflammation induced by passive cigarette smoke exposure in guinea-pigs.
A. Hernandez, L. Daffonchio, L. Brandolini, G. Zuccari
1994European Respiratory Journal6 citations Open access
Semantic Scholar
LG 30435, a new potential antiasthmatic agent.
Ferruccio Berti, L. Daffonchio, Fulvio Magni, C. Omini +2 more
1989European Respiratory Journal6 citations Open access
Semantic Scholar
Croton oil pleurisy induces pulmonary hyperreactivity.
Alicia Hernandez, L. Daffonchio, G. Brunelli, Roberto Pasargiklian +1 more
1988Pharmacological Research Communications6 citations
Semantic Scholar
Interference of the new antiinflammatory compound flunoxaprofen with eicosanoid formation in various biological systems.
F. Berti, G. Galli, C. Omini, G. Rossoni +6 more
1987Arzneimittel-Forschung6 citations
Semantic Scholar
PGD2 induces pulmonary hyperresponsiveness to acetylcholine in vivo in the guinea-pig.
G. Brunelli, L. Daffonchio, A. Hernandez, A. Sala +2 more
1987Journal of autonomic pharmacology6 citations
Semantic Scholar
Efficacy and Tolerability of Levodropropizine and Clobutinol in Elderly Patients with Nonproductive Cough
A. Pontiroli, L. Daffonchio
19975 citations
Semantic Scholar
Beta-adrenoceptor reactivity after epithelium removal in guinea-pig trachea in vitro.
L. Daffonchio, Alicia Hernandez, E. Martinotti, C. Omini
1990Pharmacological Research5 citations
Semantic Scholar
Defibrotide protects rabbit myocardium from ischemia: relationship with the eicosanoid system.
Ferruccio Berti, G. Rossini, Claudio Omini, L. Daffonchio +2 more
1987Polish journal of pharmacology and pharmacy5 citations
Semantic Scholar
Functional and biochemical modifications of lung beta-adrenoreceptors after in vivo desensitization: prevention by indomethacin.
M. Fano, M. P. Abbracchio, F. Cattabeni, L. Daffonchio +2 more
1986Journal of autonomic pharmacology5 citations
Semantic Scholar

Frequent co-authors

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C. Omini×17
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C. Omini — researcher profile on SciRah
A. Hernandez×11
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A. Hernandez — researcher profile on SciRah
Claudio Omini×10
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Claudio Omini — researcher profile on SciRah
G. Brunelli×8
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G. Brunelli — researcher profile on SciRah

Alicia Hernandez

×5

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Alicia Hernandez — researcher profile on SciRah

Ferruccio Berti×5

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Ferruccio Berti — researcher profile on SciRah

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P. Ruffini — researcher profile on SciRah

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L. Piemonti — researcher profile on SciRah

R. Novellini×4

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R. Novellini — researcher profile on SciRah

M. Allegretti×3

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M. Allegretti — researcher profile on SciRah

Gaetano Clavenna×3

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Gaetano Clavenna — researcher profile on SciRah

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I. W. Lees — researcher profile on SciRah