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L. Giovannoni · SciRah

Researcher profile · Semantic Scholar

L. Giovannoni

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L. Giovannoni — researcher profile on SciRah

h-index: 25
Works: 63
Citations: 2,624

Most-cited papers

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.
M. Santimaria, G. Moscatelli, G. Viale, L. Giovannoni +8 more
2003Clinical Cancer Research307 citations
Semantic Scholar
Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis.
F. Viti, Lorenzo Tarli, L. Giovannoni, Luciano Zardi +1 more
1999Cancer Research229 citations
Semantic Scholar
The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.
M. Johannsen, G. Spitaleri, G. Curigliano, J. Roigas +17 more
2010European Journal of Cancer182 citations
Semantic Scholar
Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study
R. Danielli, R. Patuzzo, A. D. di Giacomo, G. Gallino +11 more
2015Cancer Immunology and Immunotherapy168 citations Open access
Semantic Scholar
Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients.
S. Sauer, P. Erba, M. Petrini, A. Menrad +9 more
2009Blood168 citations
Semantic Scholar
A Dose-Escalation and Signal-Generating Study of the Immunocytokine L19-IL2 in Combination with Dacarbazine for the Therapy of Patients with Metastatic Melanoma
T. Eigentler, B. Weide, F. D. de Braud, G. Spitaleri +12 more
2011Clinical Cancer Research147 citations
Semantic Scholar
Antibody-Mediated Delivery of Interleukin-2 to the Stroma of Breast Cancer Strongly Enhances the Potency of Chemotherapy
Jessica Mårlind, Manuela Kaspar, E. Trachsel, R. Sommavilla +4 more
2008Clinical Cancer Research125 citations
Semantic Scholar
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage.
S. Demartis, A. Huber, F. Viti, L. Lozzi +4 more
1999Journal of Molecular Biology111 citations
Semantic Scholar
Antibody-Based Delivery of Interleukin-2 to Neovasculature Has Potent Activity Against Acute Myeloid Leukemia
Katrin L. Gutbrodt, C. Schliemann, L. Giovannoni, Katharina Frey +4 more
2013Science Translational Medicine105 citations
Semantic Scholar
Phase I/II study of the tumour-targeting human monoclonal antibody–cytokine fusion protein L19-TNF in patients with advanced solid tumours
G. Spitaleri, R. Berardi, Chiara Pierantoni, T. De Pas +8 more
2013Journal of Cancer Research and Clinical Oncology96 citations Open access
Semantic Scholar
Intralesional Treatment of Stage III Metastatic Melanoma Patients with L19–IL2 Results in Sustained Clinical and Systemic Immunologic Responses
B. Weide, T. Eigentler, A. Pflugfelder, H. Zelba +9 more
2014Cancer immunology research89 citations Open access
Semantic Scholar
The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity
T. Hemmerle, P. Probst, L. Giovannoni, A. Green +2 more
2013British Journal of Cancer88 citations Open access
Semantic Scholar
Isolated limb perfusion with the tumor‐targeting human monoclonal antibody–cytokine fusion protein L19‐TNF plus melphalan and mild hyperthermia in patients with locally advanced extremity melanoma
F. Papadia, V. Basso, R. Patuzzo, A. Maurichi +11 more
2013Journal of Surgical Oncology88 citations
Semantic Scholar
Radretumab Radioimmunotherapy in Patients with Brain Metastasis: A 124I-L19SIP Dosimetric PET Study
G. Poli, C. Bianchi, G. Virotta, A. Bettini +6 more
2013Cancer immunology research76 citations Open access
Semantic Scholar
Radioimmunotherapy with Radretumab in Patients with Relapsed Hematologic Malignancies
P. Erba, M. Sollini, E. Orciuolo, C. Traino +8 more
2012Journal of Nuclear Medicine72 citations Open access
Semantic Scholar
The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer
C. Catania, M. Maur, R. Berardi, A. Rocca +15 more
2015Cell Adhesion & Migration58 citations Open access
Semantic Scholar
Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients
D. Heuveling, R. de Bree, D. Vugts, M. Huisman +5 more
2013Journal of Nuclear Medicine54 citations Open access
Semantic Scholar
Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation
C. Schliemann, Katrin L. Gutbrodt, Andrea Kerkhoff, Michele Pohlen +15 more
2014Cancer immunology research45 citations Open access
Semantic Scholar
Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12.
R. Sommavilla, N. Pasche, E. Trachsel, L. Giovannoni +4 more
2010Protein engineering, design & selection : PEDS43 citations Open access
Semantic Scholar
Isolation of anti-angiogenesis antibodies from a large combinatorial repertoire by colony filter screening.
L. Giovannoni, Francesca Viti, Luciano Zardi, Dario Neri
2001Nucleic Acids Research43 citations Open access
Semantic Scholar
A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory 'armed antibody' for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate.
Mauro Galeazzi, L. Bazzichi, G. Sebastiani, D. Neri +12 more
2014The Israel Medical Association journal : IMAJ37 citations
Semantic Scholar
Radioimmunotherapy with Tenarad, a 131I-labelled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin's lymphoma
L. Aloj, L. D'Ambrosio, M. Aurilio, Anna Morisco +9 more
2014European Journal of Nuclear Medicine and Molecular Imaging33 citations
Semantic Scholar
A general method for the selection of high-level scFv and IgG antibody expression by stably transfected mammalian cells.
Kathrin Zuberbühler, A. Palumbo, C. Bacci, L. Giovannoni +4 more
2008Protein engineering, design & selection : PEDS32 citations Open access
Semantic Scholar
Armed antibodies for cancer treatment: a promising tool in a changing era
R. Danielli, R. Patuzzo, P. Ruffini, A. Maurichi +4 more
2014Cancer Immunology and Immunotherapy31 citations Open access
Semantic Scholar
Abundant in vitro expression of the oncofetal ED-B-containing fibronectin translates into selective pharmacodelivery of 131I-L19SIP in a prostate cancer patient
R. Locher, P. Erba, B. Hirsch, E. Bombardieri +4 more
2013Journal of Cancer Research and Clinical Oncology26 citations Open access
Semantic Scholar
Antibody Purification Using Membrane Adsorbers
L. Giovannoni, Marco Ventani, U. Gottschalk
200822 citations
Semantic Scholar
Combination of the immunocytokine F16-IL2 with doxorubicin or paclitaxel in patients with solid tumors: Results from two phase Ib trials.
F. D. de Braud, C. Catania, A. Onofri, Chiara Pierantoni +9 more
2011Journal of Clinical Oncology17 citations
Semantic Scholar
Combinations of the immunocytokine F16-IL2 with doxorubicin or with paclitaxel investigated in phase Ib studies in patients with advanced solid tumors.
F. D. de Braud, C. Catania, C. Masini, M. Maur +6 more
201015 citations
Semantic Scholar
Potentiating the activity of rituximab against mantle cell lymphoma in mice by targeting interleukin-2 to the neovasculature.
Niklas Börschel, C. Schwöppe, Caroline Zerbst, L. Angenendt +8 more
2015Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis14 citations
Semantic Scholar
A dose finding pharmacokinetic study of the tumor-targeting human L19-IL2 monoclonal antibody-cytokine fusion protein in patients with advanced solid tumors
G. Curigliano, G. Spitaleri, T. De Pas, C. Noberasco +6 more
200713 citations
Semantic Scholar
New Lasers For Ophthalmology: Retinal Photocoagulation With Pulsed Diode Lasers
R. Brancato, L. Giovannoni, R. Pratesi, U. Vanni
1987Other Conferences10 citations
Semantic Scholar
Recombinant antibodies for the selective targeting of tumor neovasculature.
F. Viti, L. Giovannoni, D. Neri
2002Current opinion in drug discovery & development9 citations
Semantic Scholar
Targeted ED-B fibronectin SPECT in vivo imaging in experimental atherosclerosis.
T. Dietrich, Dietmar Berndorff, T. Heinrich, T. Hucko +9 more
2015The Quarterly Journal of Nuclear Medicine and Molecular Imaging7 citations
Semantic Scholar
Phase I/II study of the tumor-targeting human L19-IL2 monoclonal antibody-cytokine fusion protein in patients with advanced renal cell carcinoma
M. Johannsen, A. Roemer, G. Spitaleri, G. Curigliano +6 more
20086 citations
Semantic Scholar
SAT0196 Dekavil (F8-IL10), A Novel Therapeutic Approach for Rheumatoid Arthritis: Ongoing Phase IB Clinical Trial Results
M. Galeazzi, G. Sebastiani, L. Bazzichi, E. Gonzalez +11 more
20155 citations
Semantic Scholar
SAT0232 A Phase IB Clinical Trial in Rheumatoid Arthritis of Dekavil (F8-IL10), A Novel Anti-Inflammatory Immunocytokine
M. Galeazzi, L. Bazzichi, G. Sebastiani, D. Neri +12 more
20145 citations
Semantic Scholar
FRI0194 A phase IB clinical trial with dekavil (F8-IL10), an anti-inflammatory immunocytokine for the treatment of rheumatoid arthritis, used in combination with methotrexate
Mauro Galeazzi, Caterina Baldi, K. Schwager, Dario Neri +2 more
20135 citations
Semantic Scholar
Radioimmunotherapy with 131I-L19SIP (Radretumab) in metastatic solid tumors: Preliminary results
G. Virotta, G. Poli, A. Bettini, C. Bianchi +5 more
20125 citations
Semantic Scholar
Tumor-targeting human L19IL2 monoclonal antibody-cytokine fusion protein in combination with DTIC in chemotherapy-naïve stage IV melanoma patients.
B. Weide, T. Eigentler, A. Romanini, F. D. de Braud +4 more
20105 citations
Semantic Scholar
Metal ion complexation and folding of linear peptides.
O. Spiga, M. Scarselli, A. Bernini, A. Ciutti +4 more
2002Biophysical Chemistry5 citations
Semantic Scholar
A phase II study of intratumoral application of L19IL2/L19TNF in melanoma patients in clinical stage III or stage IV M1a with presence of injectable cutaneous and/or subcutaneous lesions.
R. Danielli, R. Patuzzo, A. D. di Giacomo, G. Gallino +10 more
20144 citations
Semantic Scholar
Intralesional treatment of stage III metastatic melanoma patients with L19-IL2: Clinical and systemic immunological responses.
D. Neri, B. Weide, T. Eigentler, A. Pflugfelder +8 more
20144 citations
Semantic Scholar
Preliminary evaluation of radioimmunotherapy with Tenarad, a I-131 labeled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin lymphoma.
L. Aloj, L. D'Ambrosio, Michela Aurilio, R. Marreno +9 more
2011Journal of Clinical Oncology4 citations
Semantic Scholar
Immunoscintigraphic Detection of the EDB Domain of Fibronectin , a Marker of Angiogenesis , in Patients with Cancer 1
M. Santimaria, G. Moscatelli, G. Viale, L. Giovannoni +8 more
20033 citations
Semantic Scholar
Highly fluorescent protein labeling using dendritic peptide derivatives.
L. Giovannoni, L. Lozzi, Dario Neri, Paolo Neri
2000Journal of Peptide Research3 citations
Semantic Scholar
Experimental study of argon laser-induced microthrombosis during PGI2 infusion.
S. Boncinelli, P. Nerucci, M. Marsili, P. Lorenzi +4 more
1987European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes3 citations
Semantic Scholar
Phase I/II study of the tumor-targeting human L19-IL2 monoclonal antibody-cytokine fusion protein in combination with DTIC in metastatic melanoma patients.
Claus Garbe, Antonella Romanini, G. Spitaleri, L. Giovannoni +6 more
2016Journal of Clinical Oncology2 citations
Semantic Scholar
Results of a phase I/II dose-finding and efficacy study of the tumor-targeting 131I-L19SIP human recombinant mini-antibody in patients (pts) with cancer
P. Erba, M. Sollini, R. Boni, A. Traino +4 more
20102 citations
Semantic Scholar
NMR studies on Ni(II) induced cyclization of a histidine‐tagged peptide
O. Spiga, A. Bernini, M. Scarselli, A. Ciutti +4 more
2002Journal of Peptide Science2 citations
Semantic Scholar
AB0364 A Novel Approach for Rheumatoid Arthritis: Results of The Ongoing Clinical Trials with The Fully Human Immunocytokine Dekavil (F8-IL10)
Mauro Galeazzi, R. Voll, G. Sebastiani, L. Bazzichi +17 more
20161 citations
Semantic Scholar

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