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R. Costa · SciRah

Researcher profile · Semantic Scholar

R. Costa

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R. Costa — researcher profile on SciRah

h-index: 61
Works: 103
Citations: 11K

Most-cited papers

Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase
I-Ching Wang, Yi-Ju Chen, D. Hughes, V. Petrovic +5 more
2005Molecular and Cellular Biology634 citations Open access
Semantic Scholar
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes
R. Costa, D. Grayson, J. Darnell
1989Molecular and Cellular Biology507 citations Open access
Semantic Scholar
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.
E. Lai, V. Prezioso, E. Smith, Oksana Litvin +2 more
1990Genes & Development455 citations Open access
Semantic Scholar
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.
V. Kalinichenko, Michael L. Major, Xin-He Wang, V. Petrovic +7 more
2004Genes & Development385 citations Open access
Semantic Scholar
The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix
D. Overdier, A. Porcella, R. Costa
1994Molecular and Cellular Biology363 citations Open access
Semantic Scholar
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
Xin-He Wang, H. Kiyokawa, Margaret B. Dennewitz, R. Costa
2002Proceedings of the National Academy of Sciences of the United States of America341 citations Open access
Semantic Scholar
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.
Il-man Kim, Timothy Ackerson, S. Ramakrishna, M. Tretiakova +7 more
2006Cancer Research340 citations Open access
Semantic Scholar
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung.
Lan Zhou, L. Lim, R. Costa, J. Whitsett
1996Journal of Histochemistry and Cytochemistry308 citations Open access
Semantic Scholar
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice.
T. Kalin, I-Ching Wang, Timothy Ackerson, Michael L. Major +4 more
2006Cancer Research286 citations Open access
Semantic Scholar
Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators
Michael L. Major, R. Lepe, R. Costa
2004Molecular and Cellular Biology280 citations Open access
Semantic Scholar
On the epigenetic regulation of the human reelin promoter
Ying Chen, Rajiv P. Sharma, R. Costa, E. Costa +1 more
2002Nucleic Acids Res.278 citations Open access
Semantic Scholar
Chk2 Mediates Stabilization of the FoxM1 Transcription Factor To Stimulate Expression of DNA Repair Genes
Yong-Jun Tan, P. Raychaudhuri, R. Costa
2006Molecular and Cellular Biology260 citations Open access
Semantic Scholar
FoxM1, a critical regulator of oxidative stress during oncogenesis
H. Park, Janai R. Carr, Ze-Bin Wang, Veronique Nogueira +5 more
2009EMBO Journal248 citations Open access
Semantic Scholar
Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.
Senthil K. Radhakrishnan, U. Bhat, D. Hughes, I-Ching Wang +2 more
2006Cancer Research231 citations Open access
Semantic Scholar
The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis.
Katherine Krupczak-Hollis, Xin-He Wang, V. Kalinichenko, G. Gusarova +6 more
2004Developmental Biology226 citations Open access
Semantic Scholar
Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver
Xin-He Wang, Elizabeth A. Quail, Nai-Jung Hung, Yong-Jun Tan +2 more
2001Proceedings of the National Academy of Sciences of the United States of America207 citations Open access
Semantic Scholar
FoxM1 dances with mitosis
R. Costa
2005Nature Cell Biology202 citations
Semantic Scholar
Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor.
V. Kalinichenko, L. Lim, D. Stolz, B. Shin +5 more
2001Developmental Biology193 citations Open access
Semantic Scholar
Premature Expression of the Winged Helix Transcription Factor HFH-11B in Regenerating Mouse Liver Accelerates Hepatocyte Entry into S Phase
Honggang Ye, A. Holterman, K. Yoo, R. Franks +1 more
1999Molecular and Cellular Biology190 citations Open access
Semantic Scholar
The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression
Ying Guo, R. Costa, H. Ramsey, Trevor Starnes +6 more
2002Proceedings of the National Academy of Sciences of the United States of America180 citations Open access
Semantic Scholar
Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury.
You-yang Zhao, Xiao-Pei Gao, Yi-Dan Zhao, M. K. Mirza +5 more
2006Journal of Clinical Investigation175 citations
Semantic Scholar
A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes.
R. Costa, D. Grayson, K. Xanthopoulos, J. Darnell
1988Proceedings of the National Academy of Sciences of the United States of America175 citations Open access
Semantic Scholar
Differential Regulation of Interleukin-8 and Intercellular Adhesion Molecule-1 by H2O2 and Tumor Necrosis Factor-α in Endothelial and Epithelial Cells*
Venkatesh Lakshminarayanan, D. Beno, R. Costa, K. Roebuck
1997Journal of Biological Chemistry174 citations Open access
Semantic Scholar
Genesis, a Winged Helix Transcriptional Repressor with Expression Restricted to Embryonic Stem Cells*
J. Sutton, R. Costa, M. G. Klug, L. Field +7 more
1996Journal of Biological Chemistry170 citations Open access
Semantic Scholar
The Forkhead Box M1 Transcription Factor Is Essential for Embryonic Development of Pulmonary Vasculature*
Il-man Kim, S. Ramakrishna, G. Gusarova, Helena M Yoder +2 more
2005Journal of Biological Chemistry167 citations Open access
Semantic Scholar
A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment.
G. Gusarova, I-Ching Wang, Michael L. Major, V. Kalinichenko +3 more
2007Journal of Clinical Investigation165 citations Open access
Semantic Scholar
Increased Hepatic Forkhead Box M1B (FoxM1B) Levels in Old-aged Mice Stimulated Liver Regeneration through Diminished p27Kip1 Protein Levels and Increased Cdc25B Expression*
Xin-He Wang, Katherine Krupczak-Hollis, Yong-Jun Tan, Margaret B. Dennewitz +2 more
2002Journal of Biological Chemistry165 citations Open access
Semantic Scholar
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.
Y. Yoshida, I-Ching Wang, Helena M Yoder, N. Davidson +1 more
2007Gastroenterology159 citations
Semantic Scholar
The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression
U. Samadani, R. Costa
1996Molecular and Cellular Biology154 citations Open access
Semantic Scholar
Deregulation of FoxM1b leads to tumour metastasis
H. Park, G. Gusarova, Ze-Bin Wang, Janai R. Carr +10 more
2011EMBO Molecular Medicine152 citations Open access
Semantic Scholar
FoxM1 Regulates Transcription of JNK1 to Promote the G1/S Transition and Tumor Cell Invasiveness*
I-Ching Wang, Yi-Ju Chen, D. Hughes, Timothy Ackerson +6 more
2008Journal of Biological Chemistry147 citations Open access
Semantic Scholar
Anaphase-Promoting Complex/Cyclosome-Cdh1-Mediated Proteolysis of the Forkhead Box M1 Transcription Factor Is Critical for Regulated Entry into S Phase
H. Park, R. Costa, L. Lau, A. Tyner +1 more
2008Molecular and Cellular Biology131 citations Open access
Semantic Scholar
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade.
Jharna Datta, S. Majumder, Huban Kutay, Tasneem Motiwala +6 more
2007Cancer Research126 citations Open access
Semantic Scholar
The FoxM1 Transcription Factor Is Required to Maintain Pancreatic β-Cell Mass
Hongjie Zhang, Amanda M. Ackermann, G. Gusarova, D. Lowe +4 more
2006124 citations Open access
Semantic Scholar
Haploinsufficiency of the Mouse Forkhead Box f1 Gene Causes Defects in Gall Bladder Development*
V. Kalinichenko, Yan Zhou, Dibyendu Bhattacharyya, Wooram Kim +3 more
2002Journal of Biological Chemistry120 citations Open access
Semantic Scholar
β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1
Amanda Ackermann Misfeldt, R. Costa, M. Gannon
2008Diabetes113 citations Open access
Semantic Scholar
Elevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis
F. Rausa, Yong-Jun Tan, He-Ping Zhou, K. Yoo +5 more
2000Molecular and Cellular Biology108 citations Open access
Semantic Scholar
A Conserved Phosphorylation Site within the Forkhead Domain of FoxM1B Is Required for Its Activation by Cyclin-CDK1*
Yi-Ju Chen, Carmen Dominguez-Brauer, Ze-Bin Wang, J. Asara +4 more
2009Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Decreased expression of hepatocyte nuclear factor 3 alpha during the acute-phase response influences transthyretin gene transcription
X. Qian, U. Samadani, A. Porcella, R. Costa
1995Molecular and Cellular Biology101 citations Open access
Semantic Scholar
The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives.
R. S. Peterson, L. Lim, H. Ye, He-Ping Zhou +2 more
1997Mechanisms of Development100 citations Open access
Semantic Scholar
Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region.
R. Costa, D. Grayson
1991Nucleic Acids Research98 citations Open access
Semantic Scholar
The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.
Hongjie Zhang, Amanda M. Ackermann, G. Gusarova, D. Lowe +4 more
2006Molecular Endocrinology92 citations
Semantic Scholar
FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors
Ze-Bin Wang, H. Park, Janai R. Carr, Yi-Ju Chen +6 more
2011Cancer Research91 citations Open access
Semantic Scholar
An N-terminal inhibitory domain modulates activity of FoxM1 during cell cycle
Hyun-Jung Park, Ze-Bin Wang, R. Costa, A. Tyner +2 more
2008Oncogene91 citations Open access
Semantic Scholar
HNF-3/Forkhead Homologue-4 (HFH-4) Is Expressed in Ciliated Epithelial Cells in the Developing Mouse Lung
J. Tichelaar, S. Wert, R. Costa, S. Kimura +1 more
1999Journal of Histochemistry and Cytochemistry91 citations Open access
Semantic Scholar
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors
I-Ching Wang, L. Meliton, M. Tretiakova, R. Costa +2 more
2008Oncogene89 citations Open access
Semantic Scholar
Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function.
T. Unterman, Ayeesha Fareeduddin, Michael Harris, R. Goswami +3 more
1994Biochemical and Biophysical Research Communications - BBRC89 citations
Semantic Scholar
Association between Hepatocyte Nuclear Factor 6 (HNF-6) and FoxA2 DNA Binding Domains Stimulates FoxA2 Transcriptional Activity but Inhibits HNF-6 DNA Binding
F. Rausa, Yong-Jun Tan, R. Costa
2003Molecular and Cellular Biology82 citations Open access
Semantic Scholar
The Winged Helix Transcriptional Activator HFH-3 Is Expressed in the Distal Tubules of Embryonic and Adult Mouse Kidney*
D. Overdier, Honggang Ye, R. S. Peterson, D. Clevidence +1 more
1997Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Control of Apolipoprotein AI Gene Expression through Synergistic Interactions between Hepatocyte Nuclear Factors 3 and 4*
D. C. Harnish, S. Malik, E. Kilbourne, R. Costa +1 more
1996Journal of Biological Chemistry79 citations Open access
Semantic Scholar

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